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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 11 of 79

  1. Although polypharmacy has been described among cancer patients, very few studies have focused on those with lung cancer. We aimed to assess whether polypharmacy and comorbidity have an impact on systemic paren...

    Authors: Hélène Pluchart, Sébastien Bailly, Sébastien Chanoine, Denis Moro-Sibilot, Pierrick Bedouch and Anne-Claire Toffart
    Citation: BMC Cancer 2023 23:585
    Content type: Research Published on:

  2. Recently, microRNA-20a (miR-20a) has been reported to influence the clinical features and may have prognostic value in human cancers. The present meta-analysis assessed the prognostic role of miR-20a in variou...

    Authors: Donghua Huang, Yizhong Peng, Kaige Ma, Xiangyu Deng, Lu Tang, Doudou Jing and Zengwu Shao
    Citation: BMC Cancer 2018 18:1189
    Content type: Research article Published on:

  3. Inflammatory factors have increasingly become a more cost-effective prognostic indicator for gastric cancer (GC). The goal of this study was to develop a prognostic score system for gastric cancer patients bas...

    Authors: Shaobo Zhang, Hongxia Xu, Wei Li, Jiuwei Cui, Qingchuan Zhao, Zengqing Guo, Junqiang Chen, Qinghua Yao, Suyi Li, Ying He, Qiuge Qiao, Yongdong Feng, Hanping Shi and Chunhua Song
    Citation: BMC Cancer 2024 24:711
    Content type: Research Published on:

  4. Clear cell renal cell carcinoma (ccRCC) is a common malignant tumor of the urinary system characterized by poor prognosis and difficult treatment. It has been reported that iron metabolism dysregulation is a c...

    Authors: Jiyue Wu, Qing Bi, Xiang Zheng, Huawei Cao, Changzhen Hao, Zejia Sun and Wei Wang
    Citation: BMC Cancer 2022 22:1204
    Content type: Research Published on:

  5. Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with a high prevalence and poor prognosis. It is an urgent problem to deeply understand the molecular mechanism of ESCC and ...

    Authors: Honggang Liu, Menglong Jiang, Fenghui Ma, Jiapei Qin, Xin Zhou, Liqun Xu, Xiaolong Yan and Tao Jiang
    Citation: BMC Cancer 2023 23:696
    Content type: Research Published on:

  6. 8000 cases of renal cancer are diagnosed each year in the UK, with a five-year survival rate of 50 %. Treatment options are limited; a potential therapeutic target is the Src family kinases (SFKs). SFKs have r...

    Authors: Antonia K. Roseweir, Tahir Qayyum, Zhi Lim, Rachel Hammond, Alasdair I. MacDonald, Sioban Fraser, Grenville M. Oades, Michael Aitchison, Robert J. Jones and Joanne Edwards
    Citation: BMC Cancer 2016 16:229
    Content type: Research article Published on:

  8. The Wnt inhibitor Dickkopf-1 (DKK-1) has been linked to the progression of malignant bone disease by impairing osteoblast activity. In addition, there is increasing data to suggest direct tumor promoting effec...

    Authors: Tilman D Rachner, Stefanie Thiele, Andy Göbel, Andrew Browne, Susanne Fuessel, Kati Erdmann, Manfred P Wirth, Michael Fröhner, Tilman Todenhöfer, Michael H Muders, Matthias Kieslinger, Martina Rauner and Lorenz C Hofbauer
    Citation: BMC Cancer 2014 14:649
    Content type: Research article Published on:

  9. Outcome of consecutive patients with locally advanced non-small cell lung cancer and histopathologically proven mediastional lymph node metastases treated with induction chemotherapy, neoadjuvant radiochemothe...

    Authors: Christoph Pöttgen, Martin Stuschke, Britta Graupner, Dirk Theegarten, Thomas Gauler, Verena Jendrossek, Lutz Freitag, Jehad Abu Jawad, Eleni Gkika, Jeremias Wohlschlaeger, Stefan Welter, Matthias Hoiczyk, Martin Schuler, Georgios Stamatis and Wilfried Eberhardt
    Citation: BMC Cancer 2015 15:363
    Content type: Research article Published on:

  10. Baseline cardiovascular disease (CVD) can impact the patterns of treatment and hence the outcomes of patients with lung cancer. This study aimed to characterize treatment trends and survival outcomes of patien...

    Authors: Atul Batra, Dropen Sheka, Shiying Kong and Winson Y. Cheung
    Citation: BMC Cancer 2020 20:1004
    Content type: Research article Published on:

  11. Osimertinib—the third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)—has been widely used as a first-line treatment for patients with metastatic EGFR-mutant non-small cell lung...

    Authors: Soei Gen, Ichidai Tanaka, Masahiro Morise, Junji Koyama, Yuta Kodama, Akira Matsui, Ayako Miyazawa, Tetsunari Hase, Yoshitaka Hibino, Toshihiko Yokoyama, Tomoki Kimura, Norio Yoshida, Mitsuo Sato and Naozumi Hashimoto
    Citation: BMC Cancer 2022 22:654
    Content type: Research Published on:

  12. The short arm of human chromosome 3 is involved in the development of many cancers including lung cancer. Three bona fide lung cancer tumor suppressor genes namely RBSP3 (AP20 region),NPRL2 and RASSF1A (LUCA regi...

    Authors: Vera N Senchenko, Ekaterina A Anedchenko, Tatiana T Kondratieva, George S Krasnov, Alexei A Dmitriev, Veronika I Zabarovska, Tatiana V Pavlova, Vladimir I Kashuba, Michael I Lerman and Eugene R Zabarovsky
    Citation: BMC Cancer 2010 10:75
    Content type: Research article Published on:

  13. The development of lung adenocarcinoma (LUAD) involves the interactions between cell proliferation and death. Autophagy-dependent ferroptosis, a distinctive cell death process, was implicated in a multitude of...

    Authors: Huikai Miao, Qiannan Ren, Hongmu Li, Mingyue Zeng, Dongni Chen, Chunmei Xu, Youfang Chen and Zhesheng Wen
    Citation: BMC Cancer 2022 22:225
    Content type: Research Published on:

  14. The St Gallen surrogate molecular subtype definitions classify the oestrogen (ER) positive breast cancer into the luminal A and luminal B subtypes according to proliferation rate and/or expression of human epi...

    Authors: Anna-Karin Falck, Mårten Fernö, Pär-Ola Bendahl and Lisa Rydén
    Citation: BMC Cancer 2013 13:558
    Content type: Research article Published on:

  15. Pemetrexed is widely used for the treatment of advanced non-squamous non-small-cell lung cancer (NSCLC). However, factors that can predict the benefits of pemetrexed therapy have not yet been defined.

    Authors: Sojung Park, Hyun Jung Kim, Chang–Min Choi, Dae Ho Lee, Sang–We Kim, Jung–Shin Lee, Woo Sung Kim, Se Hoon Choi, Jin Kyung Rho and Jae Cheol Lee
    Citation: BMC Cancer 2016 16:417
    Content type: Research article Published on:

  16. The resistance of lung cancer to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is one of the unconquered frontiers in chemotherapy. Mitogen-inducible gene 6 (Mig-6) is known to inhibit ...

    Authors: Da Hyun Kang, Sung Soo Jung, Min-Kyung Yeo, Da Hye Lee, Geon Yoo, Sang Yeon Cho, In-Jae Oh, Ju-Ock Kim, Hee Sun Park, Chaeuk Chung and Jeong Eun Lee
    Citation: BMC Cancer 2020 20:571
    Content type: Research article Published on:

  17. Single nucleotide polymorphism (SNP) 309 resulting in a T or G allele in the promoter of MDM2, the negative regulator of p53, has been suggested to affect cancer predisposition and age of onset, primarily in fema...

    Authors: Hui Wan Chua, Daniel Ng, Serena Choo, San San Lum, Huihua Li, Li Ying Soh, Kanaga Sabapathy and Adeline Seow
    Citation: BMC Cancer 2010 10:88
    Content type: Research article Published on:

  18. To evaluate the insulin receptor isoform mRNA expression status in non-small cell lung cancer (NSCLC) patients.

    Authors: Liyan Jiang, Wei Zhu, Katie Streicher, Chris Morehouse, Philip Brohawn, Xiaoxiao Ge, Zhengwei Dong, Xiaolu Yin, Guanshan Zhu, Yi Gu, Koustubh Ranade, Brandon W Higgs, Yihong Yao and Jiaqi Huang
    Citation: BMC Cancer 2014 14:131
    Content type: Research article Published on:

  19. The CXC chemokine, CXCL12, and its receptor, CXCR4 promote metastases of a variety of solid tumors, including non-small cell lung cancer (NSCLC). The expression of CXCR4 on tumor cells may represent a critical...

    Authors: Karen L Reckamp, Robert A Figlin, Marie D Burdick, Steven M Dubinett, Robert M Elashoff and Robert M Strieter
    Citation: BMC Cancer 2009 9:213
    Content type: Research article Published on:

  20. Stereotactic irradiation (SBRT) is a standard of care for inoperable stage I lung cancer and brain oligometastases from lung cancer but is controversial for extracranial oligometastases. We assessed outcomes o...

    Authors: Manon Kissel, Isabelle Martel-Lafay, Justine Lequesne, Jean-Christophe Faivre, Cécile Le Péchoux, Dinu Stefan, Victor Barraux, Cédric Loiseau, Jean-Michel Grellard, Serge Danhier, Delphine Lerouge, Christos Chouaid, Radj Gervais and Juliette Thariat
    Citation: BMC Cancer 2019 19:1237
    Content type: Research article Published on:

  22. Metal-regulatory transcription factor 1 (MTF1), a conserved metal-binding transcription factor in eukaryotes, regulates the proliferation of cancer cells by activating downstream target genes and then particip...

    Authors: Yujing Cheng, Chan Zhang, Qi Li, Xin Yang, Wanlu Chen, KunHua He and Mingwei Chen
    Citation: BMC Cancer 2024 24:778
    Content type: Research Published on:

  23. NSCLC patients with EGFR mutation were at a higher incidence of developing brain metastasis (BM). Patients with BM are associated with high mortality. Reducing BM incidence becomes increasingly significant for...

    Authors: Wen Ouyang, Jing Yu, Yan Zhou, Jing Hu, Zhao huang, Junhong Zhang and Conghua Xie
    Citation: BMC Cancer 2020 20:699
    Content type: Research article Published on:

  24. For some patients with advanced cancer not knowing prognosis is essential. Yet, in an era of informed decision-making, the potential protective function of unawareness is easily overlooked. We aimed to investi...

    Authors: Naomi C. A. van der Velden, Hanneke W. M. van Laarhoven, Sjaak A. Burgers, Lizza E. L. Hendriks, Filip Y. F. L. de Vos, Anne-Marie C. Dingemans, Joost Jansen, Jan-Maarten W. van Haarst, Joyce Dits, Ellen MA Smets and Inge Henselmans
    Citation: BMC Cancer 2022 22:941
    Content type: Research Published on:

  25. Lung cancer causes approximately one million deaths each year worldwide and protein p53 has been shown to be involved in the intricate processes regulating response to radiation and/or chemotherapeutic treatme...

    Authors: Michael Bergqvist, Daniel Brattström, Anders Larsson, Patrik Hesselius, Ola Brodin and Gunnar Wagenius
    Citation: BMC Cancer 2004 4:66
    Content type: Research article Published on:

  26. Recent studies have reported a relationship between prognosis and neutrophil-to-lymphocyte ratio (NLR) in patients with head and neck cancer (HNC). As the results are still controversial, we conducted a meta-a...

    Authors: Yalian Yu, Hongbo Wang, Aihui Yan, Hailong Wang, Xinyao Li, Jiangtao Liu and Wei Li
    Citation: BMC Cancer 2018 18:383
    Content type: Research article Published on:

  27. Clear cell renal cell carcinoma (ccRCC) is associated with a high prevalence of cancer-related deaths. The survival rates of patients are significantly lower in late-stage ccRCC than in early-stage ccRCC, due ...

    Authors: Jun Wang, Xiaoming He, Yuanyuan Mi, Yong Q. Chen, Jie Li and Rong Wang
    Citation: BMC Cancer 2024 24:463
    Content type: Research Published on:

  28. Increasing evidence indicates that site-distant metastases are associated with survival outcomes in patients with epithelial ovarian cancer. This study aimed to investigate the prognostic values of site-distan...

    Authors: Bo Wang, Shixuan Wang and Wu Ren
    Citation: BMC Cancer 2021 21:609
    Content type: Research article Published on:

  29. Serum CYFRA 21–1 is one of the most important serum markers in the diagnosis of non-small cell lung cancer (NSCLC), especially squamous-cell carcinoma. However, it remains unknown whether pretreatment serum CY...

    Authors: Akira Ono, Toshiaki Takahashi, Keita Mori, Hiroaki Akamatsu, Takehito Shukuya, Tetsuhiko Taira, Hirotsugu Kenmotsu, Tateaki Naito, Haruyasu Murakami, Takashi Nakajima, Masahiro Endo and Nobuyuki Yamamoto
    Citation: BMC Cancer 2013 13:354
    Content type: Research article Published on:

  30. Esophageal cancer (EC) is a frequently occurring cancer with poor prognosis despite combined therapeutic strategies. Many biomarkers have been proposed as predictors of adverse events. We sought to assess the ...

    Authors: Meilan Chen, Jizheng Huang, Zhenli Zhu, Jun Zhang and Ke Li
    Citation: BMC Cancer 2013 13:539
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2014 14:892

  31. Lung cancer is the third most common type of cancer in the UK. Treatment outcomes are poor and UK deaths from lung cancer are higher than any other cancer. Prehabilitation has shown to be an important means of...

    Authors: Kelly Wade-Mcbane, Alex King, Catherine Urch, Julian Jeyasingh-Jacob, Andrew Milne and Clair Le Boutillier
    Citation: BMC Cancer 2023 23:747
    Content type: Research Published on:

  32. Cancer survivors who develop breast cancer as a second malignancy (BCa-2) are common. Yet, little is known about the prognosis of BCa-2 compared to first primary breast cancer (BCa-1).

    Authors: Chengshi Wang, Kejia Hu, Lei Deng, Wei He, Fang Fang, Rulla M. Tamimi and Donghao Lu
    Citation: BMC Cancer 2021 21:491
    Content type: Research article Published on:

  33. There is emerging evidence showing a significant relationship between overall survival (OS) in non-small cell lung cancer NSCLC patients and weight change during chemotherapy or chemoradiation. A high neutroph...

    Authors: B. A. Derman, J. N. Macklis, M. S. Azeem, S. Sayidine, S. Basu, M. Batus, F. Esmail, J. A. Borgia, P. Bonomi and M. J. Fidler
    Citation: BMC Cancer 2017 17:141
    Content type: Research article Published on:

  34. It is unknown whether and to what degree trials submitted to the US FDA to support drug approval adhere to NCCN guideline-recommended care in their baseline and surveillance CNS imaging protocols.

    Authors: John Sharp and Vinay Prasad
    Citation: BMC Cancer 2022 22:70
    Content type: Research Published on:

  35. This study was aimed at identifying prognostic biomarkers for stage II-IIIA non-small cell lung cancer (NSCLC) according to histology and at investigating the effect of vorinostat on the expression of these bi...

    Authors: Eunju Lee, DongHao Jin, Bo Bin Lee, Yujin Kim, Joungho Han, Young Mog Shim and Duk-Hwan Kim
    Citation: BMC Cancer 2015 15:982
    Content type: Research article Published on:

  36. The Will Rogers phenomenon [WRP] describes an apparent improvement in outcome for patients’ group due to tumor grade reclassification. Staging of cancers is important to select appropriate treatment and to est...

    Authors: Mary R. Nittala, Eswar K. Mundra, S. Packianathan, Divyang Mehta, Maria L. Smith, William C. Woods, Shawn McKinney, Barbara S. Craft and Srinivasan Vijayakumar
    Citation: BMC Cancer 2021 21:554
    Content type: Research article Published on:

  37. The prognostic roles of three lymph node classifications, number of positive lymph nodes (NPLN), log odds of positive lymph nodes (LODDS), and lymph node ratio (LNR) in lung adenocarcinoma are unclear. We aim ...

    Authors: Suyu Wang, Yue Yu, Wenting Xu, Xin Lv, Yufeng Zhang and Meiyun Liu
    Citation: BMC Cancer 2021 21:653
    Content type: Research Published on:

  38. To evaluate and compare the prognostic performance of four nutritional indicators body mass index (BMI), serum albumin (ALB), prognostic nutritional index (PNI) and nutritional risk index (NRI) in oral cancer ...

    Authors: Xiaodan Bao, Fengqiong Liu, Jing Lin, Qing Chen, Lin Chen, Fa Chen, Jing Wang, Yu Qiu, Bin Shi, Lizhen Pan, Lisong Lin and Baochang He
    Citation: BMC Cancer 2020 20:146
    Content type: Research article Published on:

  39. Despite today’s advances in the treatment of cancer, breast cancer-related mortality remains high, in part due to the lack of effective targeted therapies against breast tumor types that do not respond to stan...

    Authors: Carolina Di Benedetto, Justin Oh, Zainab Choudhery, Weiquan Shi, Gilmer Valdes and Paola Betancur
    Citation: BMC Cancer 2022 22:1056
    Content type: Research Published on:

  40. Extensive-stage small cell lung cancer (ES-SCLC) is an aggressive disease with poor survival, and platinum-etoposide chemotherapy is indicated as the mainstay of treatment. In this study, we compared the effic...

    Authors: Shiyu Jiang, Liling Huang, Hongnan Zhen, Peijie Jin, Jing Wang and Zhihuang Hu
    Citation: BMC Cancer 2021 21:1308
    Content type: Research Published on:

  41. Among the most common forms of cancer worldwide, breast cancer posed a serious threat to women. Recent research revealed a lack of oxygen, known as hypoxia, was crucial in forming breast cancer. This research ...

    Authors: Chaoran Qiu, Wenjun Wang, Shengshan Xu, Yong Li, Jingtao Zhu, Yiwen Zhang, Chuqian Lei, Weiwen Li, Hongsheng Li and Xiaoping Li
    Citation: BMC Cancer 2024 24:402
    Content type: Research Published on:

  42. Criteria for admitting patients with incurable diseases to the medical intensive care unit (MICU) remain unclear and have ethical implications.

    Authors: Claire Andréjak, Nicolas Terzi, Stéphanie Thielen, Emmanuel Bergot, Gérard Zalcman, Pierre Charbonneau and Vincent Jounieaux
    Citation: BMC Cancer 2011 11:159
    Content type: Research article Published on:

  43. Unplanned hospitalization during cancer treatment is costly, can disrupt treatment, and affect patient quality of life. However, incidence and risks factors for hospitalization during lung cancer radiotherapy ...

    Authors: Sarah Z. Hazell, Nicholas Mai, Wei Fu, Chen Hu, Cole Friedes, Alex Negron, Khinh Ranh Voong, Josephine L. Feliciano, Peijin Han, Samantha Myers, Todd R. McNutt and Russell K. Hales
    Citation: BMC Cancer 2020 20:334
    Content type: Research article Published on:

  44. Nodular ground-glass opacities (nGGO) are a specific type of lung adenocarcinoma. ALK rearrangements and driver mutations such as EGFR and K-ras are frequently found in all types of lung adenocarcinoma. EGFR muta...

    Authors: Sung-Jun Ko, Yeon Joo Lee, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Jin-Haeng Chung, Tae Jung Kim, Kyung Won Lee, Kwhanmien Kim, Sanghoon Jheon, Hyojin Kim, Jae Ho Lee and Choon-Taek Lee
    Citation: BMC Cancer 2014 14:312
    Content type: Research article Published on:

  45. Angiogenesis assessment is important for personalized therapeutic intervention in patients with non-small-cell lung cancer (NSCLC). This study investigated whether radiologic parameters obtained by dynamic con...

    Authors: Yu-Sen Huang, Jenny Ling-Yu Chen, Hsin-Ming Chen, Li-Hao Yeh, Jin-Yuan Shih, Ruoh-Fang Yen and Yeun-Chung Chang
    Citation: BMC Cancer 2021 21:348
    Content type: Research article Published on:

  46. NRF2 is the key regulator of oxidative stress in normal cells and aberrant expression of the NRF2 pathway due to genetic alterations in the KEAP1 (Kelch-like ECH-associated protein 1)-NRF2 (nuclear factor eryt...

    Authors: Akhileshwar Namani, Md. Matiur Rahaman, Ming Chen and Xiuwen Tang
    Citation: BMC Cancer 2018 18:46
    Content type: Research article Published on:

  47. Concomitant platinum-based chemotherapy and radiotherapy (CT-RT) is the recommended treatment for unresectable locally advanced stage III non-small cell lung cancer (NSCLC). We conducted a phase II study to ev...

    Authors: Delphine Lerouge, Alain Rivière, Eric Dansin, Christos Chouaid, Cécile Dujon, Roland Schott, Armelle Lavole, Vincent Le Pennec, Elizabeth Fabre, Jacky Crequit, Francis Martin, Stéphanie Dehette, Pierre Fournel, Bénédicte Precheur-Agulhon, Eric Lartigau and Gérard Zalcman
    Citation: BMC Cancer 2014 14:231
    Content type: Research article Published on:

  48. Approximately one third of all patients with CRC present with, or subsequently develop, colorectal liver metastases (CRLM). The objective of this population-based analysis was to assess the impact of resection...

    Authors: Alexander R. Siebenhüner, Ulrich Güller and Rene Warschkow
    Citation: BMC Cancer 2020 20:246
    Content type: Research article Published on:

  49. We aimed to study the mortality and intensity of health care in patients with advanced lung cancer who received systemic anti-cancer treatment (SACT) compared with patients who were not eligible for SACT (no-S...

    Authors: Kersti Oselin, Heti Pisarev, Keit Ilau and Raul-Allan Kiivet
    Citation: BMC Cancer 2021 21:274
    Content type: Research article Published on:

  50. Large gap exists between clinical practice and recommended care and large room exists for the improvement of care quality for non-small cell lung cancer (NSCLC) in China. Results of some studies have shown tha...

    Authors: Xinyu Wang, Shaofei Su, Shouyi Li, Han Bao, Meiqi Zhang, Dan Liu, Hao Jiang, Jiaying Wang and Meina Liu
    Citation: BMC Cancer 2017 17:603
    Content type: Research article Published on:

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