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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Our previous study showed FOXM1 expression was significantly up-regulated in cervical cancer, and was associated with poor prognosis. To clarify miRNAs-FOXM1 modulation pathways, in this study, we investigated...

    Authors: Shanyang He, Bing Liao, Yalan Deng, Chang Su, Jiuling Tuo, Jun Liu, Shuzhong Yao and Lin Xu
    Citation: BMC Cancer 2017 17:673
    Content type: Research article Published on:

  2. Interactions between cancer cells and the surrounding microenvironment are crucial determinants of cancer progression. During this process, bi-directional communication among tumor cells and cancer associated ...

    Authors: Francesca Andriani, Elena Landoni, Mavis Mensah, Federica Facchinetti, Rosalba Miceli, Elda Tagliabue, Marta Giussani, Maurizio Callari, Loris De Cecco, Mario Paolo Colombo, Luca Roz, Ugo Pastorino and Gabriella Sozzi
    Citation: BMC Cancer 2018 18:899
    Content type: Research article Published on:

  3. Several studies have proved that Polygenic Risk Score (PRS) is a potential candidate for realizing precision screening. The effectiveness of low-dose computed tomography (LDCT) screening for lung cancer has be...

    Authors: Zixuan Zhao, Shuyan Gu, Yi Yang, Weijia Wu, Lingbin Du, Gaoling Wang and Hengjin Dong
    Citation: BMC Cancer 2024 24:73
    Content type: Research Published on:

  4. Forkhead box D1, the core transcription factor member of FOX family, has gradually seen as a key cancerous regulatory. However, its expression and carcinogenicity in head and neck squamous cell carcinoma (HNSC...

    Authors: Jin Li, Tingyuan Yan, Xiang Wu, Xueping Ke, Xin Li, Yumin Zhu, Jianrong Yang and Zhongwu Li
    Citation: BMC Cancer 2021 21:1205
    Content type: Research Published on:

  5. Lung adenocarcinoma (LUAD) is the most prevalent non-small cell lung cancer (NSCLC). Patients with LUAD have a poor 5-year survival rate. The use of immune checkpoint inhibitors (ICIs) for the treatment of LUA...

    Authors: Weishuang Ma, Jiaming Liang, Junjian Mo, Siyuan Zhang, Ningdong Hu, Dongbo Tian and Zisheng Chen
    Citation: BMC Cancer 2021 21:1096
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2021 21:1146

  6. Genomic initiatives such as The Cancer Genome Atlas (TCGA) contain data from -omics profiling of thousands of tumor samples, which may be used to decipher cancer signaling, and related alterations. Managing an...

    Authors: Marta Lucchetta, Isabelle da Piedade, Mohamed Mounir, Marina Vabistsevits, Thilde Terkelsen and Elena Papaleo
    Citation: BMC Cancer 2019 19:824
    Content type: Research article Published on:

  7. Lung tuberculosis (TB) and lung cancer have a complex relationship. Data concerning TB treatment in lung cancer patients are still incomplete. The aim of this study was to investigate the effects of anti-cance...

    Authors: Mei Chai and Qingming Shi
    Citation: BMC Cancer 2020 20:1121
    Content type: Research article Published on:

  8. Epithelial cell adhesion molecule (EpCAM) has been used as surrogate marker for the quantification of circulating tumour cells (CTC). Our aim was to prospectively study the value of a real-time RT-PCR assay fo...

    Authors: Gregory Sergeant, Tania Roskams, Jos van Pelt, François Houtmeyers, Raymond Aerts and Baki Topal
    Citation: BMC Cancer 2011 11:47
    Content type: Research article Published on:

  9. The prognostic nutritional index (PNI), which is an easily calculated nutritional index, is significantly associated with patient outcomes in various solid malignancies. This study aimed to evaluate the progno...

    Authors: Takaaki Oba, Kazuma Maeno, Daiya Takekoshi, Mayu Ono, Tokiko Ito, Toshiharu Kanai and Ken-ichi Ito
    Citation: BMC Cancer 2020 20:160
    Content type: Research article Published on:

  10. Almost all of the extracellular matrix (ECM) components can be degraded by the endoproteinases matrix metalloproteinases (MMPs). Important regulators of MMPs, and thereby of the extracellular environment, are ...

    Authors: Camilla Böckelman, Ines Beilmann-Lehtonen, Tuomas Kaprio, Selja Koskensalo, Taina Tervahartiala, Harri Mustonen, Ulf-Håkan Stenman, Timo Sorsa and Caj Haglund
    Citation: BMC Cancer 2018 18:679
    Content type: Research article Published on:

  11. Non-small cell lung cancer (NSCLC) patients with interstitial lung disease (ILD) need to be approached carefully given the high incidence of pulmonary toxicity. Pemetrexed (PEM) is the key drug for the treatme...

    Authors: Motoyasu Kato, Takehito Shukuya, Fumiyuki Takahashi, Keita Mori, Kentaro Suina, Tetsuhiko Asao, Ryota Kanemaru, Yuichiro Honma, Keiko Muraki, Koji Sugano, Rina Shibayama, Ryo Koyama, Naoko Shimada and Kazuhisa Takahashi
    Citation: BMC Cancer 2014 14:508
    Content type: Research article Published on:

  12. Opioid receptors have become increasingly implicated in cancer progression and long-term patient outcomes. However, the expression and significance of the κ-opioid receptor (KOR) in hepatocellular carcinoma (H...

    Authors: Dongtai Chen, Yonghua Chen, Yan Yan, Jiahao Pan, Wei Xing, Qiang Li and Weian Zeng
    Citation: BMC Cancer 2017 17:553
    Content type: Research article Published on:

  13. Cancer cachexia in elderly patients may substantially impact physical function and medical dependency. The aim of this study was to estimate the impact of cachexia on activity of daily living (ADL), length of ...

    Authors: Tateaki Naito, Taro Okayama, Takashi Aoyama, Takuya Ohashi, Yoshiyuki Masuda, Madoka Kimura, Hitomi Shiozaki, Haruyasu Murakami, Hirotsugu Kenmotsu, Tetsuhiko Taira, Akira Ono, Kazushige Wakuda, Hisao Imai, Takuya Oyakawa, Takeshi Ishii, Shota Omori…
    Citation: BMC Cancer 2017 17:800
    Content type: Research article Published on:

  14. This study aimed to comprehensively investigate the effect of spread through air spaces (STAS) on clinicopathologic features, molecular characteristics, immunohistochemical expression, and prognosis in lung ad...

    Authors: Meng Jia, Shili Yu, Jiaqi Yu, Yuemin Li, Hongwen Gao and Ping-Li Sun
    Citation: BMC Cancer 2020 20:705
    Content type: Research article Published on:

  15. This retrospective cohort study examined the impact of tetracyclines (TCs) and proton pump inhibitors (PPIs) alone or in combination on the efficacy of epidermal growth factor receptor tyrosine kinase inhibito...

    Authors: Hui-Hsia Hsieh, Tien-Yuan Wu, Chi-Hua Chen, Yu-Hung Kuo and Mann-Jen Hour
    Citation: BMC Cancer 2023 23:151
    Content type: Research Published on:

  16. Brain metastases were rare in esophageal cancer patients. Using the Surveillance, Epidemiology, and End Results (SEER) database, the present study investigated the incidence, risk and prognostic factors of bra...

    Authors: Shizhao Cheng, Lei Yang, Xin Dai, Jing Wang and Xingpeng Han
    Citation: BMC Cancer 2021 21:1057
    Content type: Research Published on:

  17. Cancer stemness has been proven to affect tumorigenesis, metastasis, and drug resistance in various cancers, including lung squamous cell carcinoma (LUSC). We intended to develop a clinically applicable stemne...

    Authors: Jinzhi Lai, Xinyi Lin, Huangna Zheng, Bilan Xie and Deqiang Fu
    Citation: BMC Cancer 2023 23:525
    Content type: Research Published on:

  18. PTPRF interacting protein alpha 1 (PPFIA1) is reportedly related to the occurrence and progression of several kinds of malignancies. However, its role in esophageal squamous cell carcinoma (ESCC) is unclear. T...

    Authors: Yongyin Gao, Lizhao Guan, Ran Jia, Wanyi Xiao, Youming Han, Yue Li, Peng Tang, Zhentao Yu and Hongdian Zhang
    Citation: BMC Cancer 2023 23:417
    Content type: Research Published on:

  19. MicroRNAs (miRNAs) have been reported to play significant roles in non-small-cell lung cancer (NSCLC). However, the roles of microRNA (miR)-1915-3p in NSCLC remain unclear. In this study, we aimed to explore t...

    Authors: Hongli Pan, Zhenhua Pan, Fengjie Guo, Fanrong Meng, Lingling Zu, Yaguang Fan, Yang Li, Mengjie Li, Xinxin Du, Xiuwen Zhang, Yi Shao, Mingming Wei, Xuebing Li and Qinghua Zhou
    Citation: BMC Cancer 2021 21:1218
    Content type: Research Published on:

  20. Peripheral blood leukocyte (PBL) DNA methylation may serve as a surrogate marker to evaluate the susceptibility to and prognosis of gastric cancer (GC). In this study, blood-derived DNA methylation levels of t...

    Authors: Chuang Nie, Xu Han, Rongrong Wei, Anastasiia Leonteva, Jia Hong, Xinyu Du, Jing Wang, Lin Zhu, Yashuang Zhao, Yingwei Xue, Haibo Zhou and Wenjing Tian
    Citation: BMC Cancer 2021 21:551
    Content type: Research Published on:

  21. To determine the psychometric properties and minimal clinically important differences (MCIDs) of the World Health Organization Quality of Life-BREF (WHOQOL-BREF) in advanced stage lung cancer patients.

    Authors: Mark de Mol, Sabine Visser, Joachim G. J. V. Aerts, Paul Lodder, Jolanda de Vries and Brenda L. den Oudsten
    Citation: BMC Cancer 2018 18:1173
    Content type: Research article Published on:

  22. To explore the factors that affect the prognosis of overall survival (OS) and cancer-specific survival (CSS) of patients with stage IIIC1 cervical cancer and establish nomogram models to predict this prognosis.

    Authors: Yifan Feng, Ye Wang, Yangqin Xie, Shuwei Wu, Yuyang Li and Min Li
    Citation: BMC Cancer 2021 21:450
    Content type: Research Published on:

  23. Early screening and detection of lung cancer is essential for the diagnosis and prognosis of the disease. In this paper, we investigated the feasibility of serum Raman spectroscopy for rapid lung cancer screen...

    Authors: Linfang Yan, Huiting Su, Jiafei Liu, Xiaozheng Wen, Huaichao Luo, Yu Yin and Xiaoqiang Guo
    Citation: BMC Cancer 2024 24:791
    Content type: Research Published on:

  24. Anterior gradient 2 (AGR2) is a protein disulfide isomerase-like protein widely expressed in many normal tissues as well as cancers. In our study, non-neoplastic bronchial epithelial cells as well as non-small...

    Authors: Mohammed Alavi, Vei Mah, Erin L. Maresh, Lora Bagryanova, Steve Horvath, David Chia, Lee Goodglick and Alvin Y. Liu
    Citation: BMC Cancer 2015 15:655
    Content type: Research article Published on:

  25. The microscopic residual tumor at the bronchial margin after radical surgery (R1 resection) affects prognosis negatively in non-small-cell lung cancer (NSCLC) patients. For patients with good performance statu...

    Authors: Meixiang Zhou, Tao Li, Yongmei Liu, Changjin Sun, Na Li, Yong Xu, Jiang Zhu, Zhenyu Ding, Yongsheng Wang, Meijuan Huang, Feng Peng, Jin Wang, Li Ren, You Lu and Youling Gong
    Citation: BMC Cancer 2015 15:36
    Content type: Research article Published on:

  26. Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC) and is the leading cause of cancer death worldwide. Its progression is characterized by genomic instability. In turn,...

    Authors: Shuyang Li, Wei Wang, Huihan Yu, Siyu Zhang, Wenxu Bi, Suling Sun, Bo Hong, Zhiyou Fang and Xueran Chen
    Citation: BMC Cancer 2023 23:1115
    Content type: Research Published on:

  27. Patients with gastric cancer have an increased nutritional risk and experience a significant skeletal muscle loss after surgery. We aimed to determine whether muscle loss during the first postoperative year an...

    Authors: Kyung Won Kim, Koeun Lee, Jung-Bok Lee, Taeyong Park, Seungwoo Khang, Heeryeol Jeong, Chang-Seok Ko, Jeong-Hwan Yook, Byung-Sik Kim and In-Seob Lee
    Citation: BMC Cancer 2021 21:157
    Content type: Research article Published on:

  28. Repair pathway genes play an important role in the development of lung cancer. The study aimed to assess the correlation between single nucleotide polymorphisms (SNPs) in DNA repair gene (GTF2H1 and RAD54L2) and ...

    Authors: Tingting Geng, Miao Li, Rong Chen, Shuangyu Yang, Guoquan Jin, Tinabo Jin and Fulin Chen
    Citation: BMC Cancer 2022 22:1181
    Content type: Research Published on:

  29. Deregulation of the EGFR signaling pathway is one of the most frequently observed genetic abnormalities that drives cancer development. Although mutations in the downstream components of the EGFR signaling pat...

    Authors: Toshihito Suda, Takanori Hama, Shu Kondo, Yuki Yuza, Mamoru Yoshikawa, Mitsuyoshi Urashima, Takakuni Kato and Hiroshi Moriyama
    Citation: BMC Cancer 2012 12:416
    Content type: Research article Published on:

  30. MicroRNAs (miRNAs) play an important role in the regulation of cell growth, differentiation, apoptosis, and carcinogenesis. Detection of their expression may lead to identifying novel markers for breast cancer.

    Authors: Zheng-sheng Wu, Qiang Wu, Chao-qun Wang, Xiao-nan Wang, Yan Wang, Jing-jing Zhao, Shan-shan Mao, Gui-hong Zhang, Nong Zhang and Xiao-chun Xu
    Citation: BMC Cancer 2010 10:542
    Content type: Research article Published on:

  31. The expression alterations of B4GALT1 have been noted in some types of cancer and they are related to cancer cell proliferation, invasiveness, metastasis, and drug resistance. We aimed to establish the express...

    Authors: Huyang Xie, Yu Zhu, Junyu Zhang, Zheng Liu, Hangcheng Fu, Yifan Cao, Gaoxiang Li, Yijun Shen, Bo Dai, Jiejie Xu and Dingwei Ye
    Citation: BMC Cancer 2018 18:590
    Content type: Research article Published on:

  32. Maintenance therapy for non-small cell lung cancer (NSCLC) aims to extend disease control after first-line chemotherapy with active and well-tolerated agents. The utility of continuation maintenance therapy re...

    Authors: Nabil Mubarak, Rabab Gaafar, Samir Shehata, Tarek Hashem, Dani Abigeres, Hamdy A Azim, Gamal El-Husseiny, Hamed Al-Husaini and Zhixin Liu
    Citation: BMC Cancer 2012 12:423
    Content type: Research article Published on:

  33. A pathologically confirmed negative margin is required when performing sublobar resection in patients with early stage peripheral lung adenocarcinoma. However, the optimal margin distance to ensure complete tu...

    Authors: Pan Yin, Bingqing Yue, Ji Zhang, Dong Liu, Dongyu Bai, Guang Zhao, Chutong Huang, Guojun Geng, Jie Jiang, Yongxiang Su, Xiuyi Yu and Jingyu Chen
    Citation: BMC Cancer 2021 21:533
    Content type: Research Published on:

  34. This study aimed to identify new pyroptosis-associated tumor antigens for use in mRNA vaccines and the screening of sensitive LUAD populations suitable for vaccination. The association between tumor immune inf...

    Authors: Fang Zhou, Meng Wang, Zheng Wang, Wei Li and Xike Lu
    Citation: BMC Cancer 2024 24:28
    Content type: Research Published on:

  35. The insurance reimbursement rate of medical cost affects the quality and quantity of health services provided in China. The nature of this relationship, however, has not been reliably described in the field of...

    Authors: Xi Li, Qi Zhou, Xinyu Wang, Shaofei Su, Meiqi Zhang, Hao Jiang, Jiaying Wang and Meina Liu
    Citation: BMC Cancer 2018 18:683
    Content type: Research article Published on:

  36. There have been few data on the chemotherapy in elderly advanced non-small cell lung cancer (NSCLC) patients with poor performance status (PS), and usefulness of chemotherapy for such patients remains unclear....

    Authors: Satoshi Ikeda, Hiroshige Yoshioka, Satoshi Ikeo, Mitsunori Morita, Naoyuki Sone, Takashi Niwa, Akihiro Nishiyama, Toshihide Yokoyama, Akimasa Sekine, Takashi Ogura and Tadashi Ishida
    Citation: BMC Cancer 2017 17:797
    Content type: Research article Published on:

  37. Immunotherapy based on the application of immune checkpoint inhibitors (ICIs) is one of the standard treatments for advanced non-small cell lung cancer (NSCLC). Non-alcoholic fatty liver Disease (NAFLD) has de...

    Authors: Yi Li, Bingxin Gong, Yusheng Guo, Weiwei Liu, Chao Chen, Shanshan Jiang, Feng Pan, Jiyu Song, Lian Yang and Guofeng Zhou
    Citation: BMC Cancer 2024 24:535
    Content type: Research Published on:

  38. Although many intratumoral biomarkers have been reported to predict clear cell renal cell carcinoma (ccRCC) patient prognosis, combining intratumoral and clinical indicators could predict ccRCC prognosis more ...

    Authors: Chao Wang, Keqin Dong, Yuning Wang, Guang Peng, Xu Song, Yongwei Yu, Pei Shen and Xingang Cui
    Citation: BMC Cancer 2021 21:890
    Content type: Research Published on:

  39. Venous thromboembolism (VTE) occurs when blood clots in the leg, pelvic or other deep vein (deep vein thrombosis) with or without transport of the thrombus into the pulmonary arterial circulation (pulmonary em...

    Authors: Gareth O Griffiths, Sarah Burns, Simon I Noble, Fergus R Macbeth, David Cohen and Timothy S Maughan
    Citation: BMC Cancer 2009 9:355
    Content type: Study protocol Published on:

  40. Tissue inhibitor of metalloproteinase 1 (TIMP-1) is a natural inhibitor of the matrix metalloproteinases (MMPs) which are proteolytic enzymes involved in degradation of extracellular matrix thereby favoring tu...

    Authors: Karina Dahl Steffensen, Marianne Waldstrøm, Rikke Kølby Christensen, Annette Bartels, Nils Brünner and Anders Jakobsen
    Citation: BMC Cancer 2010 10:185
    Content type: Research article Published on:

  41. Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) readministration to lung cancer patients is common owing to the few options available. Impact of clinical factors on prognosis of EGFR-mu...

    Authors: Yu-Mu Chen, Chien-Hao Lai, Kun-Ming Rau, Cheng-Hua Huang, Huang-Chih Chang, Tung-Ying Chao, Chia-Cheng Tseng, Wen-Feng Fang, Yu-Hsiu Chung, Yi-Hsi Wang, Mao-Chang Su, Kuo-Tung Huang, Shih-Feng Liu, Hung-Chen Chen, Ya-Chun Chang, Yu-Ping Chang…
    Citation: BMC Cancer 2016 16:868
    Content type: Research article Published on:

  42. Cystatins are a class of proteins that can inhibit cysteine protease and are widely distributed in human bodily fluids and secretions. Cystatin SN (CST1), a member of the CST superfamily, is abnormally express...

    Authors: Jian Yang, Gaomeng Luo, Chang Li, Zhunlin Zhao, Sheng Ju, Qifan Li, Zhike Chen, Cheng Ding, Xin Tong and Jun Zhao
    Citation: BMC Cancer 2022 22:589
    Content type: Research Published on:

  43. We aim to identify the multifaceted risk factors that can affect the development of severe radiation pneumonitis (RP) in patients with non-small cell lung cancer (NSCLC) treated with curative high-dose radioth...

    Authors: Hakyoung Kim, Jeongeun Hwang, Sun Myung Kim, Juwhan Choi and Dae Sik Yang
    Citation: BMC Cancer 2023 23:992
    Content type: Research Published on:

  44. Heterogeneous ribonucleoproteins (hnRNPs) are involved in the metastasis-related network. Our previous study demonstrated that hnRNP K is associated with epithelial-to-mesenchymal transition (EMT) in A549 cell...

    Authors: Liping Li, Songxin Yan, Hua Zhang, Min Zhang, Guofu Huang and Miaojuan Chen
    Citation: BMC Cancer 2019 19:894
    Content type: Research article Published on:

  45. Lung cancer in young patients is rare and has unique clinicopathological features. However, the molecular features of lung cancer in these patients are unclear. In this study, we aimed to describe the molecula...

    Authors: Zhen Chen, Xiao Teng, Jing Zhang, Ke Huang, Qian Shen, He Cao, Huisong Luo, Yanting Yuan and Xiaodong Teng
    Citation: BMC Cancer 2019 19:777
    Content type: Research article Published on:

  46. At the present time, there is a lack of data about the involvement of flotillins and stomatin in the development of non-small cell lung cancer (NSCLC) and soft tissue sarcomas (STS). Moreover, changes in expre...

    Authors: Ksenia A Arkhipova, Anastasia N Sheyderman, Konstantin K Laktionov, Valeria V Mochalnikova and Irina B Zborovskaya
    Citation: BMC Cancer 2014 14:100
    Content type: Research article Published on:

  47. There are increasing numbers of studies of pleural tags (PTs). The purpose of this case series was to classify the PTs in patients with peripheral pulmonary adenocarcinoma based on radiologic-pathologic compar...

    Authors: Yao Meng, Jie Gao, Chongchong Wu, Mei Xie, Xidong Ma, Xuelei Zang, Jialin Song, Meng Zhou, Shikun Guo, Yemei Huang, Hengyu Deng, Hongli Li, Bo Wei and Xinying Xue
    Citation: BMC Cancer 2022 22:919
    Content type: Research Published on:

  48. The aim of the present study was to assess the efficacy of postoperative chemoradiotherapy (POCRT) following surgery in non-small-cell lung cancer patients with N2 lymph node metastasis (N2-NSCLC).

    Authors: Liyu Su, Mingqiu Chen, Huiyan Su, Yaqing Dai, Shaoxing Chen and Jiancheng Li
    Citation: BMC Cancer 2019 19:1023
    Content type: Research article Published on:

  49. Small-cell lung cancer (SCLC) is a highly proliferative, rapidly growing tumor with a poor prognosis, even in cases of limited disease (LD). Timely and accurate high-intensity therapy is necessary. For concurr...

    Authors: Seo Ree Kim, Ji Hyung Hong, Soo-Yoon Sung, Yeo Hyung Kim, Sang Hoon Chun, Hyun Woo Lee, Jung Soo Lee and Yoon Ho Ko
    Citation: BMC Cancer 2021 21:340
    Content type: Research article Published on:

  50. The landscape of non-small cell lung cancer (NSCLC) therapy is rapidly changing. This analysis aimed to understand patient characteristics, diagnosis and treatment patterns in patients with metastatic NSCLC (m...

    Authors: Hollie Bailey, Adam Lee, Laura Eccles, Yong Yuan, Helen Burlison, Cameron Forshaw and Nebibe Varol
    Citation: BMC Cancer 2023 23:603
    Content type: Research Published on:

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