Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012;487:330.
Article
Google Scholar
Geigl JB, Obenauf AC, Schwarzbraun T, Speicher MR. Trends in Genetics TIG. 2008;24:64.
Article
CAS
Google Scholar
Beroukhim R, Getz G, Nghiemphu L, Barretina J, Hsueh T, Linhart D, Vivanco I, Lee JC, Huang JH, Alexander S, Du J, Kau T, Thomas RK, Shah K, Soto H, Perner S, Prensner J, Debiasi RM, Demichelis F, Hatton C, Rubin MA, Garraway LA, Nelson SF, Liau L, Mischel PS, Cloughesy TF, Meyerson M, Golub TA, Lander ES, Mellinghoff IK, Sellers WR. Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A. 2007;104:20007.
Article
CAS
Google Scholar
Mermel CH, Schumacher SE, Hill B, Meyerson ML, Beroukhim R, Getz G. GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. Genome Biol. 2011;12:R41.
Article
Google Scholar
Barresi V, Castorina S, Musso N, Capizzi C, Luca T, Privitera G, Condorelli DF. Chromosomal instability analysis and regional tumor heterogeneity in colon cancer. Cancer Genetics. 2017;210:9.
Article
CAS
Google Scholar
Marescalco MS, Capizzi C, Condorelli DF, Barresi V. Genome-wide analysis of recurrent copy-number alterations and copy-neutral loss of heterozygosity in head and neck squamous cell carcinoma. J Oral Pathol Med. 2014;43:20.
Article
CAS
Google Scholar
Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology. 2010;138:2073.
Article
CAS
Google Scholar
Curtis LJ, Georgiades IB, White S, Bird CC, Harrison DJ, Wyllie AH. J Pathol. 2000;192:440.
Article
CAS
Google Scholar
Hugen N, Simmer F, Mekenkamp LJM, Koopman M, van den Broek E, de Wilt JHW, Punt CJA, Ylstra B, Meijer GA, Nagtegaal ID. Oncotarget. 2015;6(25715).
Lengauer C, Kinzler KW, Vogelstein B. Nature. 1998;396:643.
Article
CAS
Google Scholar
Nakao K, Mehta KR, Fridlyand J, Moore DH, Jain AN, Lafuente A, Wiencke JW, Terdiman JP, Waldman FM. Carcinogenesis. 2004;25:1345.
Article
CAS
Google Scholar
Guinney J, Dienstmann R, Wang X, de Reynis A, Schlicker A, Soneson C, Marisa L, Roepman P, Nyamundanda G, Angelino P, Bot BM, Morris JS, Simon IM, Gerster S, Fessler E, De Sousa F, Melo E, Missiaglia E, Ramay H, Barras D, Homicsko K, Maru D, Manyam GC, Broom B, Boige V, Perez-Villamil B, Laderas T, Salazar R, Gray JW, Hanahan D, Tabernero J, Bernards R, Friend SH, Laurent-Puig P, Medema JP, Sadanandam A, Wessels L, Delorenzi M, Kopetz S, Vermeulen L, Tejpar S. Nat Med. 2015;21:1350.
Article
CAS
Google Scholar
Barresi V, Romano A, Musso N, Capizzi C, Consoli C, Martelli MP, Palumbo G, Raimondo FD, Condorelli DF. Genes Chromosomes and Cancer. 2010;49:1014.
Article
CAS
Google Scholar
Barresi V, Palumbo GA, Musso N, Consoli C, Capizzi C, Meli CR, Romano A, Di Raimondo F, Condorelli DF. Leuk Res. 2010;34:1539.
Article
CAS
Google Scholar
Sveen A, Johannessen B, Tengs T, Danielsen SA, Eilertsen IA, Lind GE, Berg KCG, Leithe E, Meza-Zepeda LA, Domingo E, Myklebost O, Kerr D, Tomlinson I, Nesbakken A, Skotheim RI, Lothe RA. Genome Medicine. 2017;9(46).
Barresi V, Trovato-Salinaro A, Spampinato G, Musso N, Castorina S, Rizzarelli E, Condorelli DF. FEBS Open Bio. 2016;6:794.
Article
CAS
Google Scholar
Benjamini Y, Hochberg Y. J R Stat Soc Ser B Methodol. 1995;57:289.
Google Scholar
Höglund P, Haila S, Socha J, Tomaszewski L, Saarialho-Kere U, Karjalainen-Lindsberg M-L, Airola K, Holmberg C, de la Chapelle A, Kere J. Nat Genet. 1996;14:316.
Article
Google Scholar
Melvin JE, Park K, Richardson L, Schultheis PJ, Shull GE. J Biol Chem. 1999;274:22855.
Article
CAS
Google Scholar
Agnel M, Vermat T, Culouscou JM. FEBS Lett. 1999;455:295.
Article
CAS
Google Scholar
Comelli EM, Lariani S, Zwahlen M-C, Fotopoulos G, Holzwarth JA, Cherbut C, Dorta G, Corthésy-Theulaz I, Grigorov M. Mamm Genome. 2009;20:516.
Article
CAS
Google Scholar
Schölzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J. Am J Pathol. 2000;156:595.
Article
Google Scholar
Brenna Ø, Furnes MW, Munkvold B, Kidd M, Sandvik AK, Gustafsson BI. Cell Tissue Res. 2016;365:331.
Article
CAS
Google Scholar
Fischer H, Stenling R, Rubio C, Lindblom A. BMC Physiol. 2001;1:1.
Article
CAS
Google Scholar
Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR. Nat Biotechnol. 2011;29:1120.
Article
CAS
Google Scholar
Fleming RE, Parkkila S, Parkkila AK, Rajaniemi H, Waheed A, Sly WS. J Clin Investig. 1995;96:2907.
Article
CAS
Google Scholar
Ciardiello F, Kim N, Saeki T, Dono R, Persico MG, Plowman GD, Garrigues J, Radke S, Todaro GJ, Salomon DS. Proc Natl Acad Sci U S A. 1991;88:7792.
Article
CAS
Google Scholar
Lee MS, McGuffey EJ, Morris JS, Manyam G, Baladandayuthapani V, Wei W, Morris VK, Overman MJ, Maru DM, Jiang Z-Q, Hamilton SR, Kopetz S. Br J Cancer. 2016;114:1352.
Article
CAS
Google Scholar
Missiaglia E, Jacobs B, D’Ario G, Di Narzo AF, Soneson C, Budinska E, Popovici V, Vecchione L, Gerster S, Yan P, Roth AD, Klingbiel D, Bosman FT, Delorenzi M, Tejpar S. Ann Oncol. 2014;25:1995.
Article
CAS
Google Scholar
Qu X, Sandmann T, Frierson H, Fu L, Fuentes E, Walter K, Okrah K, Rumpel C, Moskaluk C, Lu S, Wang Y, Bourgon R, Penuel E, Pirzkall A, Amler L, Lackner MR, Tabernero J, Hampton GM, Kabbarah O. Oncogene. 2016;35:6403.
Article
CAS
Google Scholar
Bacchi CE, Gown AM. Distribution and pattern of expression of villin, a gastrointestinal-associated cytoskeletal protein, in human carcinomas: a study employing paraffin-embedded tissue. Lab Invest. 1991;64:418.
CAS
PubMed
Google Scholar
Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H, Cronin N, Beuron F. Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation. PLoS One. 2017;12:e0170508.
Article
Google Scholar
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, Karsten U, van de Wetering M, Clevers H, Schlag PM, Birchmeier W, Behrens J. Mol Cell Biol. 2002;22:1184.
Article
CAS
Google Scholar
Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nature Protoc. 2009;4:44.
Article
CAS
Google Scholar
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Duffy SM, Goldberg RM, de la Chapelle A, Koshiji M, Bhaijee T, Huebner F, Hruban RH, Wood LD, Cuka N, Pardoll DM, Papadopoulos N, Kinzler KW, Zhou S, Cornish TC, Taube JM, Anders RA, Eshleman JR, Vogelstein B, Jr Diaz LA. N Engl J Med. 2015;372:2509.
Article
CAS
Google Scholar
Conway SJ, Izuhara K, Kudo Y, Litvin J, Markwald R, Ouyang G, Arron JR, Holweg CTJ, Kudo A. The role of periostin in tissue remodeling across health and disease. Cell Mol Life Sci. 2014;71:1279.
Article
CAS
Google Scholar
Huang R, Quan Y, Huang A, Min Z. Journal of Cancer Therapy. 2016;7:729.
Article
CAS
Google Scholar
Pelli A, Väyrynen JP, Klintrup K, Mäkelä J, Mäkinen MJ, Tuomisto A, Karttunen TJ. Histopathology. 2016;69:831.
Article
Google Scholar
Jaeger E, Leedham S, Lewis A, Segditsas S, Becker M, Cuadrado PR, Davis H, Kaur K, Heinimann K, Howarth K, East J, Taylor J, Thomas H, Tomlinson I, Tomlinson I. Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1. Nat Genet. 2012;44:699.
Article
CAS
Google Scholar
Rohlin A, Eiengård F, Lundstam U, Zagoras T, Nilsson S, Edsjö A, Pedersen J, Svensson J, Skullman S, Karlsson BG, Björk J, Nordling M. Genes Chromosom Cancer. 2016;55:95.
Article
CAS
Google Scholar
Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A. Cytokine Growth Factor Rev. 2016;27:81.
Article
CAS
Google Scholar
Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, Rodenas-Cuadrado P, Mallappa S, Clark S, Thomas H, Jeffery R, Poulsom R, Rodriguez-Justo M, Novelli M, Chetty R, Silver A, Sansom OJ, Greten FR, Wang LM, East JE, Tomlinson I, Leedham SJ. Nat Med. 2014;21:62.
Article
Google Scholar
Yan K, Wu Q, Yan DH, Lee CH, Rahim N, Tritschler I, DeVecchio J, Kalady MF, Hjelmeland AB, Rich JN. Genes Dev. 2014;28:1085.
Article
CAS
Google Scholar
Khambata-Ford S, Garrett CR, Meropol NJ, Basik M, Harbison CT, Wu S, Wong TW, Huang X, Takimoto CH, Godwin AK, Tan BR, Krishnamurthi SS, Burris HA, Poplin EA, Hidalgo M, Baselga J, Clark EA, Mauro DJ. J Clin Oncol. 2007;25:3230.
Article
CAS
Google Scholar
D. J. Jonker, C. S. Karapetis, C. Harbison, C. J. O’Callaghan, D. Tu, R. J. Simes, D. P. Malone, C. Langer, N. Tebbutt, T. J. Price, J. Shapiro, L. L. Siu, R. P. W. Wong, G. Bjarnason, M. J. Moore, J. R. Zalcberg, and S. Khambata-Ford, Br J Cancer 110, 648 (2014).
Schütte M, Risch T, Abdavi-Azar N, Boehnke K, Schumacher D, Keil M, Yildiriman R, Jandrasits C, Borodina T, Amstislavskiy V, Worth CL, Schweiger C, Liebs S, Lange M, Warnatz H-J, Butcher LM, Barrett JE, Sultan M, Wierling C, Golob-Schwarzl N, Lax S, Uranitsch S, Becker M, Welte Y, Regan JL, Silvestrov M, Kehler I, Fusi A, Kessler T, Herwig R, Landegren U, Wienke D, Nilsson M, Velasco JA, Garin-Chesa P, Reinhard C, Beck S, Schäfer R, Regenbrecht CRA, Henderson D, Lange B, Haybaeck J, Keilholz U, Hoffmann J, Lehrach H, Yaspo M-L. Nat Commun. 2017;8:14262.
Article
Google Scholar
Gratchev A, Siedow A, Bumke-Vogt C, Hummel M, Foss HD, Hanski ML, Kobalz U, Mann B, Lammert H, Mansmann U, Stein H, Riecken EO, Hanski C. Cancer Lett. 2001;168:71.
Article
CAS
Google Scholar
Iwase T, Kushima R, Mukaisho K, Mitsufuji S, Okanoue T, Hattori T. Pathology - Research and Practice. 2005;201:83.
Article
CAS
Google Scholar
Aihara E, Engevik KA, Montrose MH. Annu Rev Physiol. 2017;79:357.
Article
CAS
Google Scholar
Walsh MD, Clendenning M, Williamson E, Pearson S-A, Walters RJ, Nagler B, Packenas D, Win AK, Hopper JL, Jenkins MA, Haydon AM, Rosty C, English DR, Giles GG, McGuckin MA, Young JP, Buchanan DD. Mod Pathol. 2013;26:1642.
Article
CAS
Google Scholar
Kakar S, Aksoy S, Burgart LJ, Smyrk TC. Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survival. Mod Pathol. 2004;17:696.
Article
Google Scholar
Andrici J, Farzin M, Sioson L, Clarkson A, Watson N, Toon CW, Gill AJ. Mismatch repair deficiency as a prognostic factor in mucinous colorectal cancer. Mod Pathol. 2016;29:266.
Article
CAS
Google Scholar
Perez-Villamil B, Romera-Lopez A, Hernandez-Prieto S, Lopez-Campos G, Calles A, Lopez-Asenjo J-A, Sanz-Ortega J, Fernandez-Perez C, Sastre J, Alfonso R, Caldes T, Martin-Sanchez F, Diaz-Rubio E. BMC Cancer. 2012;12(260).
van Beelen Granlund A, Østvik AE, Brenna Ø, Torp SH, Gustafsson BI, Sandvik AK. Cell Tissue Res. 2013;352:639.
Article
CAS
Google Scholar
Oue N, Kuniyasu H, Noguchi T, Sentani K, Ito M, Tanaka S, Setoyama T, Sakakura C, Natsugoe S, Yasui W. Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasis. Oncology. 2007;72:371.
Article
CAS
Google Scholar
Kaprio T, Hagström J, Mustonen H, Koskensalo S, Andersson LC, Haglund C. REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PLoS One. 2014;9:e109600.
Article
Google Scholar
Altmann GG. Am J Anat. 1983;167:95.
Article
CAS
Google Scholar
Sasaki N, Sachs N, Wiebrands K, Ellenbroek SIJ, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, Li VSW, Lopez-Iglesias C, Peters PJ, van Rheenen J, van Oudenaarden A, Clevers H. Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon. Proc Natl Acad Sci. 2016;113:E5399.
Article
CAS
Google Scholar
Rothenberg ME, Nusse Y, Kalisky T, Lee JJ, Dalerba P, Scheeren F, Lobo N, Kulkarni S, Sim S, Qian D, Beachy PA, Pasricha PJ, Quake SR, Clarke MF. Gastroenterology. 2012;142:1195.
Article
CAS
Google Scholar
Davoli T, Uno H, Wooten EC, Elledge SJ. Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy. Science. 2017;20:355.
Google Scholar
Taylor AM, Shih J, Ha G, Gao GF, Zhang X, Berger AC, Schumacher SE, Wang C, Hu H, Liu J, Lazar AJ. Cancer genome atlas research Network, a.D. Cherniack, R. Beroukhim, M. Meyerson. Cancer Cell. 2018;33:676.
Article
CAS
Google Scholar
Nitsche U, Friess H, Agha A, Angele M, Eckel R, Heitland W, Jauch KW, Krenz D, Nüssler NC, Rau HG, Ruppert R, Schubert-Fritschle G, Wilhelm D, Werner J, Engel J. Prognosis of mucinous and signet-ring cell colorectal cancer in a population-based cohort. J Cancer Res Clin Oncol. 2016;142:2357.
Article
Google Scholar