Table 2 Thresholds for identification of specifically or shared downregulated DEGs
From: Gene expression profiles in genome instability-based classes of colorectal cancer
CRC groups | |||
|---|---|---|---|
specifically downregulated DEGs | |||
HB vs N | LB vs N | MSI vs N | |
HB | FC < −2 and FDR < 0.05 | FC > −2 and FDR > 0.05 | FC > − 2 and FDR > 0.05 |
LB | FC > −2 and FDR > 0.05 | FC < − 2 and FDR < 0.05 | FC > − 2 and FDR > 0.05 |
MSI | FC > − 2 and FDR > 0.05 | FC > − 2 and FDR > 0.05 | FC < − 2 and FDR < 0.05 |
shared downregulated DEGs | |||
HB vs N | LB vs N | MSI vs N | |
HB and LB | FC < −2 and FDR < 0.05 | FC < −2 and FDR < 0.05 | FC > − 2 and FDR > 0.05 |
LB and MSI | FC > −2 and FDR > 0.05 | FC < − 2 and FDR < 0.05 | FC < − 2 and FDR < 0.05 |
HB and MSI | FC < − 2 and FDR < 0.05 | FC > − 2 and FDR > 0.05 | FC < − 2 and FDR < 0.05 |
HB, LB and MSI | FC < − 2 and FDR < 0.05 | FC < − 2 and FDR < 0.05 | FC < − 2 and FDR < 0.05 |