Malvezzi M, Bertuccio P, Rosso T, Rota M, Levi F, La Vecchia C, Negri E. European cancer mortality predictions for the year 2015: does lung cancer have the highest death rate in EU women? Ann Oncol. 2015;26:779–86.
Article
CAS
PubMed
Google Scholar
Ilie M, Hofman V, Dietel M, Soria JC, Hofman P. Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients. Virchows Arch. 2016;468(5):511–25.
Article
CAS
PubMed
Google Scholar
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA cancer J. 2012;62:10–29.
Article
Google Scholar
Malhotra J, Malvezzi M, Negri E, La Vecchia C, Boffetta P. Risk factors for lung cancer worldwide. Eur Respir J. 2016;48(3):889–902.
Article
PubMed
Google Scholar
Young RP, Hopkins RJ, Hay BA, Epton MJ, Mills GD, Black PN, Gardner HD, Sullivan R, Gamble GD. COPD prevalence is increased in lung cancer, independent of age, sex and smoking history. Eur Respir J. 2009;34:380–6.
Article
CAS
PubMed
Google Scholar
Wilson DO, Weissfeld JL, Balkan A, et al. Association of radiographic emphysema and airflow obstruction with lung cancer. Am J Respir Crit Care Med. 2008;178:738–44.
Article
PubMed
PubMed Central
Google Scholar
Skillrud DM, Offord KP, Miller RD. Higher risk of lung Cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled Study. Ann Intern Med. 1986;105:503–7.
Article
CAS
PubMed
Google Scholar
Wasswa-kintu S, Gan WQ, Man SF, Pare PD, Sin DD. Relationship between reduced forced expiratory volume in one second and the risk of lung cancer: a systematic review and meta-analysis. Thorax. 2005;60(7):570–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Calabrò E, Randi G, La Vecchia C, Sverzellati N, Marchiano A, Villani M, Zompatori M, Cassandro R, Harari S, Pastorino U. Lung function predicts lung cancer risk in smokers: a tool for targeting screening programmes. Eur Respir J. 2010;35:146–51.
Article
PubMed
Google Scholar
Gullon JA, Suarez I, Medina A, Rubinos G, Fernandez R, Gonzalez I. Role of emphysema and airway obstruction in prognosis of lung cancer. Lung Cancer. 2011;71:182–5.
Article
CAS
PubMed
Google Scholar
Smith BM, Schwartzman K, Kovacina B, et al. Lung cancer histologies associated with emphysema on computed tomography. Lung Cancer. 2012;76:61–6.
Article
PubMed
Google Scholar
Gao YH, Guan WJ, Liu Q, Wang HQ, Zhu YN, Chen RC, Zhang GJ. Impact of COPD and emphysema on survival of patients with lung cancer: a meta-analysis of observational studies. Respirology. 2016;21(2):269–79.
Article
PubMed
Google Scholar
Murakami J, Ueda K, Sano F, Hayashi M, Nishimoto A, Hamano K. Pulmonary emphysema and tumor microenvironment in primary lung cancer. J Surg Res. 2016;200(2):690–7.
Article
PubMed
Google Scholar
Zhai R, Yu X, Shafer A, Wain JC, Christiani DC. The impact of coexisting COPD on survival of patients with early-stage non-small cell lung cancer undergoing surgical resection. Chest. 2014;145(2):346–53.
Article
PubMed
Google Scholar
Kuo CH, Wu CY, Lee KY, Lin SM, Chung FT, Lo YL, Liu CY, Hsiung TC, Yang CT. Wu YC. Chronic obstructive pulmonary disease in stage I non-small cell lung cancer that underwent anatomic resection: the role of a recurrence promoter. COPD. 2014;11(4):407–13.
Article
PubMed
Google Scholar
Wiegman CH, Michaeloudes C, Haji G, et al. Oxidative stress-induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol. 2015;136:769–80.
Article
CAS
PubMed
PubMed Central
Google Scholar
Senft D, Ronai ZA. Regulators of mitochondrial dynamics in cancer. Curr Opin Cell Biol. 2016;39:43–52.
Article
CAS
PubMed
PubMed Central
Google Scholar
Remark R, Becker C, Gomez JE, Damotte D, Dieu-Nosjean MC, Sautès-Fridman C, Fridman WH, Powell CA, Altorki NK, Merad M, Gnjatic S. The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome. Am J Respir Crit Care Med. 2015;191(4):377–90.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wu P, Wu D, Zhao L, et al. Inverse role of distinct subsets and distribution of macrophage in lung cancer prognosis: a meta-analysis. Oncotarget. 2016;7(26):40451–60.
PubMed
PubMed Central
Google Scholar
EL M, LA O'N. Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal. Eur J Immunol. 2016;46(1):13–21. https://doi.org/10.1002/eji.201445427.
Article
CAS
Google Scholar
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102:15545–50.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gentles AJ, Newman AM, Liu CL, et al. The prognostic landscape of genes and infiltrating immune cells across human cancers. Nat Med. 2015;21:938–45.
Article
CAS
PubMed
PubMed Central
Google Scholar
Li JR, Sun CH, Li W, et al. Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells. Nucleic Acids Res. 2016;44(D1):D944–51.
Article
CAS
PubMed
Google Scholar
Fedchenko N, Reifenrath J. Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue - a review. Diagn Pathol. 2014;9:221.
Article
PubMed
PubMed Central
Google Scholar
Ishibashi H, Suzuki T, Suzuki S, et al. Sex steroid hormone receptors in human thymoma. J Clin Endocrinol Metab. 2003;88:2309–17.
Article
CAS
PubMed
Google Scholar
Hanzelmann S, Castelo R, Guinney J. GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinformatics. 2013;14:7.
Article
PubMed
PubMed Central
Google Scholar
Bao Z, Zhang C, Yan W, et al. BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas. J Trans Med. 2013;11:100.
Article
CAS
Google Scholar
Xue J, Schmidt SV, Sander J, et al. Transcriptome-based network analysis reveals a Spectrum model of human Macrophage activation. Immunity. 2014;40:274–88.
Article
CAS
PubMed
PubMed Central
Google Scholar
Okayama H, Kohno T, Ishii Y, et al. Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. Cancer Res. 2012;72:100–11.
Article
CAS
PubMed
Google Scholar
Aramburu A, Zudaire I, Pajares MJ, et al. Combined clinical and genomic signatures for the prognosis of early stage non-small cell lung cancer based on gene copy number alterations. BMC Genomics. 2015;16:752.
Article
PubMed
PubMed Central
Google Scholar
Lu H, Li G, Liu L, et al. Regulation and function of mitophagy in development and cancer. Autophagy. 2013;9:1720–36.
Article
CAS
PubMed
Google Scholar
Kulikov AV, Luchkina EA, Gogvadze V, Zhivotovsky B. Mitophagy: Link to cancer development and therapy. Biochem Biophys Res Commun. 2017;15;482(3):432–9. https://doi.org/10.1016/j.bbrc.2016.10.088.
Ito S, Araya J, Kurita Y, et al. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis. Autophagy. 2015;11:547–59.
Article
PubMed
PubMed Central
Google Scholar
Mizumura K, Cloonan SM, Nakahira K, et al. Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD. J Clin Invest. 2014;124:3987–4003.
Article
CAS
PubMed
PubMed Central
Google Scholar
Marnett LJ. Oxyradicals and DNA damage. Toxicology. 2000;21:361–70.
CAS
Google Scholar
Geeraerts X, Bolli E, Fendt SM, Van Ginderachter JA, Macrophage Metabolism A. Therapeutic target for cancer, atherosclerosis, and Obesity. Front Immunol. 2017;8:289.
Article
PubMed
PubMed Central
Google Scholar
Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012;148:228–43.
Article
CAS
PubMed
Google Scholar
Lu W, Sun J, Yoon YS, et al. Mitochondrial protein PGAM5 regulates Mitophagic protection against cell necroptosis. PLoS One. 2016;11:e0147792.
Article
PubMed
PubMed Central
Google Scholar
Chen G, Han Z, Feng D, et al. A regulatory signaling loop comprising the PGAM5 phosphatase and CK2 controls receptor-mediated mitophagy. Mol Cell. 2014;54:362–77.
Article
CAS
PubMed
Google Scholar
Moriwaki K, Farias Luz N, Balaji S, et al. The mitochondrial phosphatase PGAM5 is dispensable for necroptosis but promotes Inflammasome activation in macrophages. J Immunol. 2016;196(1):407–15.
Article
CAS
PubMed
Google Scholar
Vlahos R, Bozinovski S. Role of alveolar macrophages in chronic obstructive pulmonary disease. Front Immunol. 2014;5:1–7.
Article
CAS
Google Scholar