Figure 3
From: Lack of correlation between MYCN expression and the Warburg effect in neuroblastoma cell lines
Neuroblastoma cell lines produced lactate in the presence of the oxidative phosphorylation inhibitor, rotenone. Culture media from neuroblastoma cell lines incubated â– with or â–¡ without rotenone to inhibit oxidative phosphorylation was assayed for extracellular lactate as a measure of glycolysis. BE(2)-C and NBL-S cell lines produced significantly more (*p < 0.01, #p < 0.05) lactate per mg of total cellular protein when cultured in the presence of rotenone.