McGuire JJ, Bertino JR: Enzymatic synthesis and function of folylpolyglutamates. Mol Cell Biochem. 1981, 38 Spec No (Pt 1): 19-48. 10.1007/BF00235686.
Article
CAS
PubMed
Google Scholar
McGuire JJ, Hsieh P, Coward JK, Bertino JR: Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its products. J Biol Chem. 1980, 255 (12): 5776-5788.
CAS
PubMed
Google Scholar
Moran RG, Colman PD, Rosowsky A, Forsch RA, Chan KK: Structural features of 4-amino antifolates required for substrate activity with mammalian folylpolyglutamate synthetase. Mol Pharmacol. 1985, 27 (1): 156-166.
CAS
PubMed
Google Scholar
Synold TW, Willits EM, Barredo JC: Role of folylpolygutamate synthetase (FPGS) in antifolate chemotherapy; a biochemical and clinical update. Leuk Lymphoma. 1996, 21 (1-2): 9-15.
Article
CAS
PubMed
Google Scholar
Baldwin SW, Tse A, Gossett LS, Taylor EC, Rosowsky A, Shih C, Moran RG: Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase. Biochemistry. 1991, 30 (7): 1997-2006. 10.1021/bi00221a037.
Article
CAS
PubMed
Google Scholar
Jackman AL, Taylor GA, Gibson W, Kimbell R, Brown M, Calvert AH, Judson IR, Hughes LR: ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Cancer Res. 1991, 51 (20): 5579-5586.
CAS
PubMed
Google Scholar
Rots MG, Willey JC, Jansen G, Van Zantwijk CH, Noordhuis P, DeMuth JP, Kuiper E, Veerman AJ, Pieters R, Peters GJ: mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method. Leukemia. 2000, 14 (12): 2166-2175. 10.1038/sj.leu.2401943.
Article
CAS
PubMed
Google Scholar
Barredo J, Moran RG: Determinants of antifolate cytotoxicity: folylpolyglutamate synthetase activity during cellular proliferation and development. Mol Pharmacol. 1992, 42 (4): 687-694.
CAS
PubMed
Google Scholar
Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE: Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood. 1994, 84 (2): 564-569.
CAS
PubMed
Google Scholar
Egan MG, Sirlin S, Rumberger BG, Garrow TA, Shane B, Sirotnak FM: Rapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation. J Biol Chem. 1995, 270 (10): 5462-5468. 10.1074/jbc.270.10.5399.
Article
CAS
PubMed
Google Scholar
Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE: Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity. Mol Pharmacol. 1997, 52 (1): 155-163.
CAS
PubMed
Google Scholar
Chen L, Qi H, Korenberg J, Garrow TA, Choi YJ, Shane B: Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene. J Biol Chem. 1996, 271 (22): 13077-13087. 10.1074/jbc.271.22.13077.
Article
CAS
PubMed
Google Scholar
Freemantle SJ, Taylor SM, Krystal G, Moran RG: Upstream organization of and multiple transcripts from the human folylpoly-gamma-glutamate synthetase gene. J Biol Chem. 1995, 270 (16): 9579-9584. 10.1074/jbc.270.16.9579.
Article
CAS
PubMed
Google Scholar
Turner FB, Taylor SM, Moran RG: Expression patterns of the multiple transcripts from the folylpolyglutamate synthetase gene in human leukemias and normal differentiated tissues. J Biol Chem. 2000, 275 (46): 35960-35968. 10.1074/jbc.M005228200.
Article
CAS
PubMed
Google Scholar
Leclerc GJ, Barredo JC: Folylpoly-gamma-glutamate synthetase gene mRNA splice variants and protein expression in primary human leukemia cells, cell lines, and normal human tissues. Clin Cancer Res. 2001, 7 (4): 942-951.
CAS
PubMed
Google Scholar
Turner FB, Andreassi 2nd JL, Ferguson J, Titus S, Tse A, Taylor SM, Moran RG: Tissue-specific expression of functional isoforms of mouse folypoly-gamma-glutamae synthetase: a basis for targeting folate antimetabolites. Cancer Res. 1999, 59 (24): 6074-6079.
CAS
PubMed
Google Scholar
Freemantle SJ, Moran RG: Transcription of the human folylpoly-gamma-glutamate synthetase gene. J Biol Chem. 1997, 272 (40): 25373-25379. 10.1074/jbc.272.40.25373.
Article
CAS
PubMed
Google Scholar
Leclerc GJ, Leclerc GM, Barredo JC: Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines. Cancer Cell Int. 2002, 2 (1): 1-10.1186/1475-2867-2-1.
Article
PubMed
PubMed Central
Google Scholar
Hanson RD, Connolly NL, Burnett D, Campbell EJ, Senior RM, Ley TJ: Developmental regulation of the human cathepsin G gene in myelomonocytic cells. J Biol Chem. 1990, 265 (3): 1524-1530.
CAS
PubMed
Google Scholar
Antequera F, Boyes J, Bird A: High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell. 1990, 62 (3): 503-514. 10.1016/0092-8674(90)90015-7.
Article
CAS
PubMed
Google Scholar
Razin A, Cedar H: DNA methylation and gene expression. Microbiol Rev. 1991, 55 (3): 451-458.
CAS
PubMed
PubMed Central
Google Scholar
Brown ST, Miranda GA, Galic Z, Hartman IZ, Lyon CJ, Aguilera RJ: Regulation of the RAG-1 promoter by the NF-Y transcription factor. J Immunol. 1997, 158 (11): 5071-5074.
CAS
PubMed
Google Scholar
Nomura M, Bartsch S, Nawata H, Omura T, Morohashi K: An E box element is required for the expression of the ad4bp gene, a mammalian homologue of ftz-f1 gene, which is essential for adrenal and gonadal development. J Biol Chem. 1995, 270 (13): 7453-7461. 10.1074/jbc.270.13.7453.
Article
CAS
PubMed
Google Scholar
Chodosh LA, Baldwin AS, Carthew RW, Sharp PA: Human CCAAT-binding proteins have heterologous subunits. Cell. 1988, 53 (1): 11-24. 10.1016/0092-8674(88)90483-7.
Article
CAS
PubMed
Google Scholar
Zhu QS, Qian B, Levy D: CCAAT/enhancer-binding protein alpha (C/EBPalpha) activates transcription of the human microsomal epoxide hydrolase gene (EPHX1) through the interaction with DNA-bound NF-Y. J Biol Chem. 2004, 279 (29): 29902-29910. 10.1074/jbc.M400438200.
Article
CAS
PubMed
Google Scholar
Mantovani R: The molecular biology of the CCAAT-binding factor NF-Y. Gene. 1999, 239 (1): 15-27. 10.1016/S0378-1119(99)00368-6.
Article
CAS
PubMed
Google Scholar
Kurioka H, Kishi H, Isshiki H, Tagoh H, Mori K, Kitagawa T, Nagata T, Dohi K, Muraguchi A: Isolation and characterization of a TATA-less promoter for the human RAG-1 gene. Mol Immunol. 1996, 33 (13): 1059-1066. 10.1016/S0161-5890(96)00062-4.
Article
CAS
PubMed
Google Scholar
Huang DY, Kuo YY, Lai JS, Suzuki Y, Sugano S, Chang ZF: GATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B gene. Nucleic Acids Res. 2004, 32 (13): 3935-3946. 10.1093/nar/gkh719.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cassel DL, Subudhi SK, Surrey S, McKenzie SE: GATA and NF-Y participate in transcriptional regulation of FcgammaRIIA in megakaryocytic cells. Blood Cells Mol Dis. 2000, 26 (6): 587-597. 10.1006/bcmd.2000.0337.
Article
CAS
PubMed
Google Scholar
Liang F, Schaufele F, Gardner DG: Functional interaction of NF-Y and Sp1 is required for type a natriuretic peptide receptor gene transcription. J Biol Chem. 2001, 276 (2): 1516-1522. 10.1074/jbc.M006350200.
Article
CAS
PubMed
Google Scholar
Cross SH, Bird AP: CpG islands and genes. Curr Opin Genet Dev. 1995, 5 (3): 309-314. 10.1016/0959-437X(95)80044-1.
Article
CAS
PubMed
Google Scholar
Rosowsky A: Chemistry and biological activity of antifolates. Prog Med Chem. 1989, 26: 1-252.
Article
CAS
PubMed
Google Scholar
MethPrimer - Design Primers for Methylation PCRs. [http://urogene.org/methprimer/index1.html]
Genomatix, MatInspector program. [http://www.genomatix.de/cgi-bin/tools/tools.pl]