Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM: Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010, 127 (12): 2893-2917. 10.1002/ijc.25516.
Article
CAS
PubMed
Google Scholar
Payne SJ, Bowen RL, Jones JL, Wells CA: Predictive markers in breast cancer–the present. Histopathology. 2008, 52 (1): 82-90.
Article
CAS
PubMed
Google Scholar
Cserni G, Francz M, Jaray B, Kalman E, Kovacs I, Kulka J, Orosz Z, Udvarhelyi N, Vass L: Pathologic diagnosis and histopathology record of breast cancer. Magy Onkol. 2010, 54 (3): 217-226. 10.1556/MOnkol.54.2010.3.3.
Article
PubMed
Google Scholar
Kuroi K, Toi M, Tsuda H, Kurosumi M, Akiyama F: Issues in the assessment of the pathologic effect of primary systemic therapy for breast cancer. Breast Cancer. 2006, 13 (1): 38-48. 10.2325/jbcs.13.38.
Article
PubMed
Google Scholar
Mittendorf EA, Jeruss JS, Tucker SL, Kolli A, Newman LA, Gonzalez-Angulo AM, Buchholz TA, Sahin AA, Cormier JN, Buzdar AU, et al: Validation of a novel staging system for disease-specific survival in patients with breast cancer treated with neoadjuvant chemotherapy. J Clin Oncol. 2011, 29 (15): 1956-1962. 10.1200/JCO.2010.31.8469.
Article
PubMed
PubMed Central
Google Scholar
Sahoo S, Lester SC: Pathology of breast carcinomas after neoadjuvant chemotherapy: an overview with recommendations on specimen processing and reporting. Arch Pathol Lab Med. 2009, 133 (4): 633-642.
PubMed
Google Scholar
Shien T, Shimizu C, Seki K, Shibata T, Hojo T, Ando M, Kohno T, Katsumata N, Akashi-Tanaka S, Kinoshita T, et al: Comparison among different classification systems regarding the pathological response of preoperative chemotherapy in relation to the long-term outcome. Breast Cancer Res Treat. 2009, 113 (2): 307-313. 10.1007/s10549-008-9935-2.
Article
PubMed
Google Scholar
Jeruss JS, Mittendorf EA, Tucker SL, Gonzalez-Angulo AM, Buchholz TA, Sahin AA, Cormier JN, Buzdar AU, Hortobagyi GN, Hunt KK: Combined use of clinical and pathologic staging variables to define outcomes for breast cancer patients treated with neoadjuvant therapy. J Clin Oncol. 2008, 26 (2): 246-252. 10.1200/JCO.2007.11.5352.
Article
CAS
PubMed
Google Scholar
Jeruss JS, Mittendorf EA, Tucker SL, Gonzalez-Angulo AM, Buchholz TA, Sahin AA, Cormier JN, Buzdar AU, Hortobagyi GN, Hunt KK: Staging of breast cancer in the neoadjuvant setting. Cancer Res. 2008, 68 (16): 6477-6481. 10.1158/0008-5472.CAN-07-6520.
Article
CAS
PubMed
PubMed Central
Google Scholar
Czyz J: The stage-specific function of gap junctions during tumourigenesis. Cell Mol Biol Lett. 2008, 13 (1): 92-102. 10.2478/s11658-007-0039-5.
Article
CAS
PubMed
Google Scholar
Goodenough DA, Paul DL: Gap junctions. Cold Spring Harb Perspect Biol. 2009, 1 (1): a002576-10.1101/cshperspect.a002576.
Article
PubMed
PubMed Central
Google Scholar
Vinken M, Vanhaecke T, Papeleu P, Snykers S, Henkens T, Rogiers V: Connexins and their channels in cell growth and cell death. Cell Signal. 2006, 18 (5): 592-600. 10.1016/j.cellsig.2005.08.012.
Article
CAS
PubMed
Google Scholar
Rackauskas M, Neverauskas V, Skeberdis VA: Diversity and properties of connexin gap junction channels. Medicina (Kaunas). 2010, 46 (1): 1-12.
Google Scholar
Houghton FD: Role of gap junctions during early embryo development. Reproduction. 2005, 129 (2): 129-135. 10.1530/rep.1.00277.
Article
CAS
PubMed
Google Scholar
Krysko DV, Leybaert L, Vandenabeele P, D'Herde K: Gap junctions and the propagation of cell survival and cell death signals. Apoptosis. 2005, 10 (3): 459-469. 10.1007/s10495-005-1875-2.
Article
CAS
PubMed
Google Scholar
Herve JC, Derangeon M, Sarrouilhe D, Giepmans BN, Bourmeyster N: Gap junctional channels are parts of multiprotein complexes. Biochim Biophys Acta. 2012, 1818 (8): 1844-1865. 10.1016/j.bbamem.2011.12.009.
Article
CAS
PubMed
Google Scholar
Locke D: Gap junctions in normal and neoplastic mammary gland. J Pathol. 1998, 186 (4): 343-349. 10.1002/(SICI)1096-9896(199812)186:4<343::AID-PATH189>3.0.CO;2-X.
Article
CAS
PubMed
Google Scholar
Pointis G, Fiorini C, Gilleron J, Carette D, Segretain D: Connexins as precocious markers and molecular targets for chemical and pharmacological agents in carcinogenesis. Curr Med Chem. 2007, 14 (21): 2288-2303. 10.2174/092986707781696564.
Article
CAS
PubMed
Google Scholar
Cronier L, Crespin S, Strale PO, Defamie N, Mesnil M: Gap junctions and cancer: new functions for an old story. Antioxid Redox Signal. 2009, 11 (2): 323-338. 10.1089/ars.2008.2153.
Article
CAS
PubMed
Google Scholar
Oviedo-Orta E, Errington RJ, Evans WH: Gap junction intercellular communication during lymphocyte transendothelial migration. Cell Biol Int. 2002, 26 (3): 253-263. 10.1006/cbir.2001.0840.
Article
CAS
PubMed
Google Scholar
Kanczuga-Koda L, Sulkowska M, Koda M, Rutkowski R, Sulkowski S: Increased expression of gap junction protein–connexin 32 in lymph node metastases of human ductal breast cancer. Folia Histochem Cytobiol. 2007, 45 (Suppl 1): S175-S180.
PubMed
Google Scholar
Kanczuga-Koda L, Sulkowski S, Lenczewski A, Koda M, Wincewicz A, Baltaziak M, Sulkowska M: Increased expression of connexins 26 and 43 in lymph node metastases of breast cancer. J Clin Pathol. 2006, 59 (4): 429-433. 10.1136/jcp.2005.029272.
Article
CAS
PubMed
PubMed Central
Google Scholar
McLachlan E, Shao Q, Laird DW: Connexins and gap junctions in mammary gland development and breast cancer progression. J Membr Biol. 2007, 218 (1–3): 107-121.
Article
CAS
PubMed
Google Scholar
Banerjee D, Gakhar G, Madgwick D, Hurt A, Takemoto D, Nguyen TA: A novel role of gap junction connexin46 protein to protect breast tumours from hypoxia. Int J Cancer. 2010, 127 (4): 839-848.
CAS
PubMed
PubMed Central
Google Scholar
Fattaneh A, Tavassoli PD: WHO Series, Tumours of the Breast and Female Genital Organs. 2003, 18-19.
Google Scholar
Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, et al: American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol. 2007, 25 (1): 118-145.
Article
CAS
PubMed
Google Scholar
Kononen J, Bubendorf L, Kallioniemi A, Barlund M, Schraml P, Leighton S, Torhorst J, Mihatsch MJ, Sauter G, Kallioniemi OP: Tissue microarrays for high-throughput molecular profiling of tumour specimens. Nat Med. 1998, 4 (7): 844-847. 10.1038/nm0798-844.
Article
CAS
PubMed
Google Scholar
Theurillat JP, Zurrer-Hardi U, Varga Z, Barghorn A, Saller E, Frei C, Storz M, Behnke S, Seifert B, Fehr M, et al: Distinct expression patterns of the immunogenic differentiation antigen NY-BR-1 in normal breast, testis and their malignant counterparts. Int J Cancer. 2008, 122 (7): 1585-1591.
Article
CAS
PubMed
Google Scholar
Sohl G, Willecke K: Gap junctions and the connexin protein family. Cardiovasc Res. 2004, 62 (2): 228-232. 10.1016/j.cardiores.2003.11.013.
Article
PubMed
Google Scholar
Krenacs T, Ficsor L, Varga SV, Angeli V, Molnar B: Digital microscopy for boosting database integration and analysis in TMA studies. Methods in molecular biology (Clifton, NJ). 2010, 664: 163-175. 10.1007/978-1-60761-806-5_16.
Article
Google Scholar
Miglietta L, Vanella P, Canobbio L, Naso C, Cerisola N, Meszaros P, Parodi MA, Morabito F: Prognostic value of estrogen receptor and Ki-67 index after neoadjuvant chemotherapy in locally advanced breast cancer expressing high levels of proliferation at diagnosis. Oncology. 2010, 79 (3–4): 255-261.
Article
CAS
PubMed
Google Scholar
Kyo N, Yamamoto H, Takeda Y, Ezumi K, Ngan CY, Terayama M, Miyake M, Takemasa I, Ikeda M, Doki Y, et al: Overexpression of connexin 26 in carcinoma of the pancreas. Oncol Rep. 2008, 19 (3): 627-631.
PubMed
Google Scholar
Tate AW, Lung T, Radhakrishnan A, Lim SD, Lin X, Edlund M: Changes in gap junctional connexin isoforms during prostate cancer progression. Prostate. 2006, 66 (1): 19-31. 10.1002/pros.20317.
Article
CAS
PubMed
Google Scholar
Liu X, Furuya T, Li D, Xu J, Cao X, Li Q, Xu Z, Sasaki K: Connexin 26 expression correlates with less aggressive phenotype of intestinal type-gastric carcinomas. Int J Mol Med. 2010, 25 (5): 709-716.
Article
CAS
PubMed
Google Scholar
Nomura S, Maeda K, Noda E, Inoue T, Fukunaga S, Nagahara H, Hirakawa K: Clinical significance of the expression of connexin26 in colorectal cancer. J Exp Clin Cancer Res. 2010, 29: 79-10.1186/1756-9966-29-79.
Article
PubMed
PubMed Central
Google Scholar
Bier A, Oviedo-Landaverde I, Zhao J, Mamane Y, Kandouz M, Batist G: Connexin43 pseudogene in breast cancer cells offers a novel therapeutic target. Mol Cancer Ther. 2009, 8 (4): 786-793. 10.1158/1535-7163.MCT-08-0930.
Article
CAS
PubMed
Google Scholar
Kamei J, Toyofuku T, Hori M: Negative regulation of p21 by beta-catenin/TCF signaling: a novel mechanism by which cell adhesion molecules regulate cell proliferation. Biochem Biophys Res Commun. 2003, 312 (2): 380-387. 10.1016/j.bbrc.2003.10.129.
Article
CAS
PubMed
Google Scholar
Lee SW, Tomasetto C, Paul D, Keyomarsi K, Sager R: Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumour cell lines. J Cell Biol. 1992, 118 (5): 1213-1221. 10.1083/jcb.118.5.1213.
Article
CAS
PubMed
Google Scholar
Conklin C, Huntsman D, Yorida E, Makretsov N, Turbin D, Bechberger JF, Sin WC, Naus CC: Tissue microarray analysis of connexin expression and its prognostic significance in human breast cancer. Cancer Lett. 2007, 255 (2): 284-294. 10.1016/j.canlet.2007.05.001.
Article
CAS
PubMed
Google Scholar
Kulka J, Tokes AM, Toth AI, Szasz AM, Farkas A, Borka K, Jaray B, Szekely E, Istok R, Lotz G, et al: Immunohistochemical phenotype of breast carcinomas predicts the effectiveness of primary systemic therapy. Magy Onkol. 2009, 53 (4): 335-343. 10.1556/MOnkol.53.2009.4.2.
Article
PubMed
Google Scholar
Neubauer H, Gall C, Vogel U, Hornung R, Wallwiener D, Solomayer E, Fehm T: Changes in tumour biological markers during primary systemic chemotherapy (PST). Anticancer Res. 2008, 28 (3B): 1797-1804.
PubMed
Google Scholar
van de Ven S, Smit VT, Dekker TJ, Nortier JW, Kroep JR: Discordances in ER, PR and HER2 receptors after neoadjuvant chemotherapy in breast cancer. Cancer Treat Rev. 2011, 37 (6): 422-430.
CAS
PubMed
Google Scholar
Varga Z, Caduff R, Pestalozzi B: Stability of the HER2 gene after primary chemotherapy in advanced breast cancer. Virchows Arch. 2005, 446 (2): 136-141. 10.1007/s00428-004-1164-4.
Article
CAS
PubMed
Google Scholar
Darb-Esfahani S, Loibl S, Muller BM, Roller M, Denkert C, Komor M, Schluns K, Blohmer JU, Budczies J, Gerber B, et al: Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapy. Breast Cancer Res. 2009, 11 (5): R69-10.1186/bcr2363.
Article
PubMed
PubMed Central
Google Scholar
Denkert C, Sinn BV, Issa Y, Maria Muller B, Maisch A, Untch M, von Minckwitz G, Loibl S: Prediction of Response to Neoadjuvant Chemotherapy: New Biomarker Approaches and Concepts. Breast Care (Basel). 2011, 6 (4): 265-272.
Google Scholar
Guiu S, Gauthier M, Coudert B, Bonnetain F, Favier L, Ladoire S, Tixier H, Guiu B, Penault-Llorca F, Ettore F, et al: Pathological complete response and survival according to the level of HER-2 amplification after trastuzumab-based neoadjuvant therapy for breast cancer. Br J Cancer. 2010, 103 (9): 1335-1342. 10.1038/sj.bjc.6605939.
Article
CAS
PubMed
PubMed Central
Google Scholar
Precht LM, Lowe KA, Atwood M, Beatty JD: Neoadjuvant chemotherapy of breast cancer: tumour markers as predictors of pathologic response, recurrence, and survival. Breast J. 2010, 16 (4): 362-368.
PubMed
Google Scholar
Untch M, Fasching PA, Konecny GE, Hasmuller S, Lebeau A, Kreienberg R, Camara O, Muller V, du Bois A, Kuhn T, et al: Pathologic complete response after neoadjuvant chemotherapy plus trastuzumab predicts favorable survival in human epidermal growth factor receptor 2-overexpressing breast cancer: results from the TECHNO trial of the AGO and GBG study groups. J Clin Oncol. 2011, 29 (25): 3351-3357. 10.1200/JCO.2010.31.4930.
Article
CAS
PubMed
Google Scholar
von Minckwitz G, Sinn HP, Raab G, Loibl S, Blohmer JU, Eidtmann H, Hilfrich J, Merkle E, Jackisch C, Costa SD, et al: Clinical response after two cycles compared to HER2, Ki-67, p53, and bcl-2 in independently predicting a pathological complete response after preoperative chemotherapy in patients with operable carcinoma of the breast. Breast Cancer Res. 2008, 10 (2): R30-10.1186/bcr1989.
Article
PubMed
PubMed Central
Google Scholar
Osako T, Horii R, Matsuura M, Ogiya A, Domoto K, Miyagi Y, Takahashi S, Ito Y, Iwase T, Akiyama F: Common and discriminative clinicopathological features between breast cancers with pathological complete response or progressive disease in response to neoadjuvant chemotherapy. J Cancer Res Clin Oncol. 2010, 136 (2): 233-241. 10.1007/s00432-009-0654-9.
Article
CAS
PubMed
Google Scholar