Expression of connexin isotypes in breast cancers before and after neoadjuvant chemotherapy (A). Dynamic changes in connexin isotype expression in the 50 (in Cx43, 51) matched breast cancer samples upon treatment (B-E). Cx26 (B) and Cx32 (C) levels mostly decreased, Cx43 (D) levels revealed the least change, while Cx46 (E) levels were mainly increased. Green lines represent decrease, red lines highlight increase. Violet symbols alone represent no change in expression.