Warburg O, Wind F, Neglein E: Metabolism of tumours in the body. J Gen Physiol. 1927, 8: 519-530. 10.1085/jgp.8.6.519.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gatenby RA, Gillies RJ: Why do cancers have high aerobic glycolysis?. Nat Rev Cancer. 2004, 4: 891-899. 10.1038/nrc1478.
Article
CAS
PubMed
Google Scholar
Izumi H, Torigoe T, Ishiguchi H, Uramoto H, Yoshida Y, Tanabe M, Ise T, Murakami T, Yoshida T, Nomoto M, Kohno K: Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Cancer Treat Rev. 2003, 29: 541-549. 10.1016/S0305-7372(03)00106-3.
Article
CAS
PubMed
Google Scholar
Semenza GL, Artemov D, Bedi A, Bhujwalla Z, Chiles K, Feldser D, Laughner E, Ravi R, Simons J, Taghavi P, Zhong H: The metabolism of tumours: 70 years later. Novartis Found Symp. 2001, 240: 251-260.
Article
CAS
PubMed
Google Scholar
Halestrap AP, Price NT: The proton-linked monocarboxylate transporter MCT. Family: structure, function and regulation. Biochem J. 1999, 343: 281-299. 10.1042/0264-6021:3430281.
Article
CAS
PubMed
PubMed Central
Google Scholar
Pinheiro C, Longatto-Filho A, Scapulatempo C, Ferreira L, Martins S, Pellerin L, Rodrigues M, Alves VA, Schmitt F, Baltazar F: Increased expression of monocarboxylate transporters 1, 2 and 4 in colorectal carcinomas. Virchows Arch. 2008, 452: 139-146. 10.1007/s00428-007-0558-5.
Article
CAS
PubMed
Google Scholar
Pinheiro C, Longatto-Filho A, Ferreira L, Pereira S, Etlinger D, Moreira M, Jubé L, Queiroz G, Schmitt F, Baltazar F: Increasing expression of monocarboxylate transporters 1 and 4 along progression to invasive cervical carcinoma. Int J Gynec Pathol. 2008, 27: 568-574. 10.1097/PGP.0b013e31817b5b40.
Article
Google Scholar
Wahl ML, Owen JA, Burd R, Herlands RA, Nogami S, Rodeck U, Berd D, Leeper DB, Owen CS: Regulation of intracellular pH in human melanoma:potential therapeutic implications. Mol Cancer Ther. 2002, 37: 617-628.
Google Scholar
Pinheiro C, Albergaria A, Paredes J, Sousa B, Dufloth R, Vieira D, Schmitt F, Baltazar F: Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma. Histopathology. 2010, 56: 860-867. 10.1111/j.1365-2559.2010.03560.x.
Article
PubMed
Google Scholar
Pinheiro C, Reis RM, Ricardo S, Longatto-Filho A, Schmitt F, Baltazar F: Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44. J Biomed Biotechnol. 2010, 2010: 427694-Epub 2010 May 4
Article
PubMed
PubMed Central
Google Scholar
Koukourakis MI, Giatromanolaki A, Bougioukas G, Sivridis E: Lung cancer: a comparative study of metabolism related protein expression in cancer cells and tumour associated stroma. Cancer Biol Ther. 2007, 6: 1476-1479. 10.4161/cbt.6.9.4635.
Article
CAS
PubMed
Google Scholar
Gomes N, Vizcaíno JR, Pinheiro C, Baltazar F: Monocarboxylate transporters 2 and 4 are upregulated in prostate carcinoma. Virchows Arch. 2009, 455 (Supplement: Suppl. 1): 233-
Google Scholar
Gomes N, Vizcaíno JR, Pinheiro C, Baltazar F: Characterization of monocarboxylate transporters expression in prostate carcinoma. Microsc Microanal. 2009, 15 (Supplement S3): 17-18.
Article
CAS
Google Scholar
Hao J, Chen H, Madigan MC, Cozzi PJ, Beretov J, Xiao W, Delprado WJ, Russell PJ, Li Y: Co-expression of CD147 (EMMPRIN), CD44v3-10, MDRI and monocarboxylate transporters is associated with prostate cancer drug resistance and progression. Br J Cancer. 2010, 103 (7): 1008-1018. 10.1038/sj.bjc.6605839.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kirk P, Wilson MC, Heddle C, Brown MH, Barclay AN, Halestrap AP: CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J. 2000, 19: 3896-3904. 10.1093/emboj/19.15.3896.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP: Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J Biol Chem. 2005, 280: 27213-27221. 10.1074/jbc.M411950200.
Article
CAS
PubMed
Google Scholar
Deora AA, Philp N, Hu J, Bok D, Rodriguez-Boulan E: Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. Proc Natl Acad Sci USA. 2005, 102: 16245-16250. 10.1073/pnas.0504419102.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gallagher SM, Castorino JJ, Wang D, Philp NJ: Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. Cancer Res. 2007, 67: 4182-4189. 10.1158/0008-5472.CAN-06-3184.
Article
CAS
PubMed
Google Scholar
Nabeshima K, Iwasaki H, Koga K, Hojo H, Suzumiya J, Kikuchi M: Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression. Pathol Int. 2006, 56: 359-367. 10.1111/j.1440-1827.2006.01972.x.
Article
CAS
PubMed
Google Scholar
Gabison EE, Hoang-Xuan T, Mauviel A, Menashi S: EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie. 2005, 87: 361-368. 10.1016/j.biochi.2004.09.023.
Article
CAS
PubMed
Google Scholar
Riethdorf S, Reimers N, Assmann V, Kornfeld JW, Terracciano L, Sauter G, Pantel K: High incidence of EMMPRIN expression in human tumors. Int J Cancer. 2006, 19: 1800-1810.
Article
Google Scholar
Zhao-Dong H, Xue-Cheng B, Wei-jun Q, He H, Dai Q, Zou J, Ye Y, Liang Y, Zeng G, Chen Z, Zhong W: CD147 Expression indicates unfavourable prognosis in prostate cancer. Pathol Oncol. 2009, 15: 369-374. 10.1007/s12253-008-9131-z.
Article
Google Scholar
Zhong WD, Han ZD, He HC, Bi XC, Dai QS, Zhu G, Ye YK, Liang YX, Qin WJ, Zhang Z, Zeng GH, Chen ZN: CD147, MMP-1, MMP-2 and MMP-9 protein expression as significant prognostic factors in human prostate cancer. Oncology. 2008, 75: 230-236. 10.1159/000163852.
Article
CAS
PubMed
Google Scholar
Madigan MC, Kingsley EA, Cozzi PJ, Madigan MC, Kingsley EA, Cozzi PJ, Delprado W, Russel P, Li Y: The role of extracellular matrix metalloproteinase inducer protein in prostate cancer progression. Cancer Immunol Immunother. 2008, 57: 1367-1379. 10.1007/s00262-008-0473-x.
Article
CAS
PubMed
Google Scholar
Han ZD, He HC, Bi XC, Qin WJ, Dai QS, Zou J, Ye YK, Liang YX, Zeng GH, Zhu G, Chen ZN, Zhong WD: Expression and clinical significance of CD147 in genitourinary carcinomas. J Surg Res. 2010, 160: 260-267. 10.1016/j.jss.2008.11.838.
Article
CAS
PubMed
Google Scholar
Epstein J, Allsbrook W, Amin M, Egevad LL, ISUP Grading Committee: The 2005 International Society of Urological Pathology (ISUP) Consensus conference on gleason grading of prostatic carcinoma. Am J Sur Pathol. 2005, 29: 1228-1242. 10.1097/01.pas.0000173646.99337.b1.
Article
Google Scholar
Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A: AJCC cancer staging manual. 2010, Chicago:Springer, 7
Google Scholar
Damber JE, Aus G: Prostate cancer. Lancet. 2008, 371: 1710-1721. 10.1016/S0140-6736(08)60729-1.
Article
PubMed
Google Scholar
Mathupala SP, Parajuli P, Sloan AE: Silencing of monocarboxylate transporters via small interfering ribonucleic acid inhibits glycolysis and induces cell death in malignant glioma: an in vitro study. Neurosurgery. 2004, 55: 1410-1419.
Article
PubMed
Google Scholar
Sonveaux P, Vegran F, Schroeder T, Wergin M, Verrax J, Rabbani ZN, Saedeleer CJ, Kennedy KM, Diepart C, Jordan BF, Kelley MJ, Gallez B, Wahl ML, Feron O, Dewhirst MW: Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest. 2008, 118: 3930-3942.
CAS
PubMed
PubMed Central
Google Scholar
Slomiany MG, Grass GD, Robertson AD: Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res. 2009, 69: 1293-1301. 10.1158/0008-5472.CAN-08-2491.
Article
CAS
PubMed
PubMed Central
Google Scholar
Legaspi A, Jeevanandam M, Starnes HF, Brennan MF: Whole body lipid and energy metabolism in the cancer patient. Metabolism. 1987, 36: 958-963. 10.1016/0026-0495(87)90132-6.
Article
CAS
PubMed
Google Scholar
Luo J, Zha S, Gage WR, Dunn TA, Hicks JL, Bennett CJ, Ewing CM, Platz EA, Ferdinandusse S, Wanders RJ, Trent JM, Isaacs WB, De Marzo AM: α-Methylacyl-CoA racemase: a new molecular marker for prostate cancer. Cancer Res. 2002, 62: 2220-2226.
CAS
PubMed
Google Scholar
McClelland G, Khanna S, Brooks G: Peroxisomal membrane monocarboxylate transporters: evidence for a redox shuttle system?. Biochem Biophys Res Commun. 2003, 304: 130-135. 10.1016/S0006-291X(03)00550-3.
Article
CAS
PubMed
Google Scholar