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Table 3 Correlations between monocarboxylate transporters (MCTs) and CD147 expressions in prostate tumour samples and clinico-pathological data

From: Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer

   

MCT1

   

MCT2

  

MCT4

  

CD147

  

Variable

n

ISG %(n)

p

HSG %(n)

p

ISG %(n)

p

HSG %(n)

p

ISG %(n)

p

HSG %(n)

p

ISG %(n)

p

HSG %(n)

p

Age

  

0.391

 

0.073

 

0.023

 

0.117

 

0.247

 

< 0.001

 

0.518

 

< 0.001

> 64

93

19.4 (18)

 

40.9 (38)

 

32.6 (30)

 

48.4 (45)

 

18.5 (17)

 

8.6 (8)

 

17.2 (16)

 

16.1 (15)

 

> 64

73

16.4 (12)

 

53.4 (39)

 

17.8 (13)

 

58.9 (43)

 

24.0 (18)

 

42.3 (31)

 

16.2 (12)

 

54.1 (40)

 

PSA (ng/ml)

  

0.414

 

0.016

 

0.085

 

0.250

 

0.060

 

< 0.001

 

0.529

 

< 0.001

> 11

116

19 (22)

 

40.5 (47)

 

29.6 (34)

 

50.9 (116)

 

17.2 (20)

 

11.1 (13)

 

17.1 (20)

 

16.2 (19)

 

> 11

50

16 (8)

 

60.0 (30)

 

18.0 (9)

 

58.0 (50)

 

29.4 (15)

 

51.0 (26)

 

16.0 (8)

 

72.0 (36)

 

pT

  

0.511

 

0.145

 

0.528

 

0.297

 

0.210

 

< 0.001

 

0.396

 

< 0.001

2

130

18.5 (24)

 

43.8 (57)

 

26.4 (34)

 

51.5 (67)

 

19.2 (25)

 

14.5 (19)

 

16.0 (21)

 

24.4 (32)

 

3

36

16.7 (6)

 

55.6 (20)

 

25.0 (3)

 

58.3 (21)

 

27.0 (10)

 

54.1 (20)

 

19.4 (7)

 

63.9 (23)

 

Gleason score

  

0.251

 

0.170

 

0.386

 

0.857

 

0.692

 

0.011

 

0.850

 

0.012

< 7

57

15.8 (9)

 

52.6 (30)

 

31.6 (18)

 

54.4 (31)

 

24.6 (14)

 

10.5 (6)

 

15.8 (9)

 

21.1 (12)

 

7

100

21.0 (21)

 

41.0 (41)

 

22.2 (22)

 

53.0 (53)

 

18.8 (19)

 

28.4 (29)

 

17.8 (18)

 

36.6 (36)

 

> 7

9

0 (0)

 

66.7 (6)

 

33.3 (3)

 

44.4 (4)

 

22.2 (2)

 

44.4 (4)

 

11.1 (1)

 

66.7 (6)

 

Perineural

                 

Invasion

  

0.525

 

0.036

 

0.503

 

0.259

 

0.397

 

0.011

 

0.531

 

0.021

Absent

52

17.3 (9)

 

57.7 (30)

 

26.9 (14)

 

57.7 (30)

 

23.1 (12)

 

11.5 (6)

 

17.3 (9)

 

21.2 (11)

 

Present

114

18.4 (21)

 

41.2 (47)

 

25.7 (29)

 

50.9 (58)

 

20.0 (23)

 

28.4 (33)

 

16.5 (19)

 

38.3 (44)

 

Biochemical

                 

Recurrence

  

0.434

 

0.047

 

0.597

 

0.089

 

0.200

 

< 0.001

 

0.489

 

< 0.001

Absent

139

18.7 (26)

 

43.2 (60)

 

26.1 (36)

 

50.4 (70)

 

19.4 (27)

 

17.1 (24)

 

16.4 (23)

 

26.4 (37)

 

Present

27

14.8 (4)

 

63.0 (17)

 

25.9 (7)

 

66.7 (18)

 

28.6 (8)

 

53.6 (15)

 

18.5 (5)

 

66.7 (18)

 
  1. ISG, intermediate score group; HSG, high score group.