Greenle RT, Hill-Harmon MB, Thun M: Errata. CA Cancer J Clin. 2001, 51: 15-36. 10.3322/canjclin.51.1.15.
Article
Google Scholar
Slamon D, Clark M, Wong S, Levin W, Ullrich A, McAuire W: Detection of c-erbB-2 amplification in breast cancer by in situ hybridization. Science. 1987, 235: 177-181. 10.1126/science.3798106.
Article
CAS
PubMed
Google Scholar
Menard S, Tagliabue E, Campiglio M, Pupa SM: Role of HER2 gene overexpression in breast carcinoma. J Cell Physiol. 2000, 182: 150-162. 10.1002/(SICI)1097-4652(200002)182:2<150::AID-JCP3>3.0.CO;2-E.
Article
CAS
PubMed
Google Scholar
Fernández Val JF, Losada J, Arregui Murua MA, Sarría R: Cell proliferation, nuclear ploidy, and EGFR and HER2/neu tyrosine kinase oncoproteins in infiltrating ductal breast carcinoma. Cancer Genetics and Cytogenetics. 2002, 138: 69-72. 10.1016/S0165-4608(02)00567-8.
Article
PubMed
Google Scholar
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A: The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer. 2001, 8: 11-31. 10.1677/erc.0.0080011.
Article
CAS
PubMed
Google Scholar
Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fahrenbacher L, Wolter JM, Paton V, Shak S, Lieberman G, et al: Multinational study of the efficacy and safety of humanized anti-Her2 monoclonal antibody in women who have Her2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol. 1999, 17: 2639-2648.
CAS
PubMed
Google Scholar
Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, Fleming T, Eiermann W, Wolter J, Pegram M, et al: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med. 2001, 344: 783-792. 10.1056/NEJM200103153441101.
Article
CAS
PubMed
Google Scholar
Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, Tripathy D, Baly D, Baughman SA, Twaddell T, Glaspy JA, et al: Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol. 1998, 16: 2659-2671.
CAS
PubMed
Google Scholar
Baselga J, Tripathy D, Mendelsohn J, Baughman S, Benz CC, Dantis L, Sklarin NT, Seidman AD, Hudis CA, Moore J, et al: Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol. 1996, 14: 737-744.
CAS
PubMed
Google Scholar
Romond EH, Perez EA, Bryant J, Suman VJ, Geyer CE, Davidson NE, Tan-Chiu E, Martino S, Paik S, Kaufman PA, et al: Trastuzumab plus chemotherapy for operable HER2-positive breast cancer. N Engl J Med. 2005, 353: 1673-1684. 10.1056/NEJMoa052122.
Article
CAS
PubMed
Google Scholar
Piccart-Gebhart MJ, Proctor M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I, Gianni L, Baselga J, Bell R, Jackisch C, et al: Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med. 2005, 353: 1659-1672. 10.1056/NEJMoa052306.
Article
CAS
PubMed
Google Scholar
Clynes RA, Towers TL, Presta LG, Ravetch JV: Inhibitory Fc receptors modulates in vivo cytotoxicity against tumor targets. Nat Med. 2000, 6: 443-446. 10.1038/74704.
Article
CAS
PubMed
Google Scholar
Sreedhar AS, Kalmar E, Csermely P, Shen YF: Hsp90 isoforms: functions, expression and clinical importance. FEBS Lett. 2004, 562: 11-15. 10.1016/S0014-5793(04)00229-7.
Article
PubMed
Google Scholar
Meares GP, Zmijewska AA, Jope RS: Heat shock protein-90 dampens and directs signaling stimulated by insulin-like growth factor-1 and insulin. FEBS Lett. 2004, 574: 181-186. 10.1016/j.febslet.2004.08.026.
Article
CAS
PubMed
PubMed Central
Google Scholar
Citri A, Kochupurakkal BS, Yarden Y: The achilles heel of ErbB-2/HER2: Regulation by the Hsp90 chaperone machine and potential for pharmacological intervention. Cell Cycle. 2004, 3: 51-60. 10.4161/cc.3.1.607.
Article
CAS
PubMed
Google Scholar
Wolfgang HS, Obermann MJ, Russo AA, Pavletich NP, Hartl FU: In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol. 1998, 143: 901-910. 10.1083/jcb.143.4.901.
Article
Google Scholar
Stirling PC, Bakhoum SF, Feigl AB, Leroux MR: Convergent evolution of clamp-like binding sites inn diverse chaperones. Nat Struct Mol Biol. 2006, 13: 865-870. 10.1038/nsmb1153.
Article
CAS
PubMed
Google Scholar
Fiore C, Tezeguet V, LeSaux A, Roux P, Schwimmer C, Dianoux AC, Noel F, Lauquin GJM, Brandolin G, Vignais PV: The mitochondrial ADP/ATP carrier: structural, physiological and pathological aspects. Biochimie. 1998, 80: 137-150. 10.1016/S0300-9084(98)80020-5.
Article
CAS
PubMed
Google Scholar
Jang JY, Choi Y, Jeon YK, Kim CW: Suppression of adenine nucleotide translocase-2 by vector-based siRNA in human breast cancer cells induces apoptosis and inhibits tumor growth in vitro and in vivo. Breast Cancer Research. 2008, 10: R11-10.1186/bcr1857.
Article
PubMed
PubMed Central
Google Scholar
Rao J: Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer. 2003, 3: 489-501. 10.1038/nrc1121.
Article
CAS
PubMed
Google Scholar
Werb Z: ECM and cell surface proteolysis: regulating cellular ecology. Cell. 1997, 91: 439-442. 10.1016/S0092-8674(00)80429-8.
Article
CAS
PubMed
Google Scholar
Fang J, Shing Y, Wiederschain D, Yan L, Butterfield C, Jackson G, Harper J, Tamvakopoulos G, Moses MA: Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model. Proc Nat l Acad Sci USA. 2000, 97: 3884-3889. 10.1073/pnas.97.8.3884.
Article
CAS
Google Scholar
Sternlicht MD, Werb Z: How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol. 2001, 17: 463-516. 10.1146/annurev.cellbio.17.1.463.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mignatti P, Tsuboi R, Robbins E, Rifkin DB: In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases. J Cell Biol. 1989, 108: 671-682. 10.1083/jcb.108.2.671.
Article
CAS
PubMed
Google Scholar
Cornelius LA, Nehring LC, Roby JD, Parks WC, Welgus HG: Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration. J Invest Dermatol. 1995, 105: 170-176. 10.1111/1523-1747.ep12317080.
Article
CAS
PubMed
Google Scholar
Hanemaaijer R, Koolwijk P, Le Clercq L, de Vree WJA, van Hinsbergh VWM: Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Biochem J. 1993, 296: 803-809.
Article
CAS
PubMed
PubMed Central
Google Scholar
Unemori EN, Bouhana KS, Werb Z: Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells. J Biol Chem. 1990, 265: 445-451.
CAS
PubMed
Google Scholar
Eric I, Tara LH: JNK and PI3K differentially regulate MMP-2 and MT1-MMP mRNA and protein in response to actin cytoskeleton reorganization in endothelial cells. Am J Physiol Cell Physiol. 2006, 291: 579-588. 10.1152/ajpcell.00300.2005.
Article
Google Scholar
García-Ruiz C, Colell A, Morales A, Calvo M, Enrich C, Fernández-Checa JC: Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha. J Biol Chem. 2002, 277: 16396-16402. 10.1074/jbc.M200877200.
Article
Google Scholar
Wang S, Liu Q, Zhang Y, Liu K, Yu P, Liu K, Luan J, Duan H, Lu Z, Wang F, Wu E, Yagasaki K, et al: Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. Molecular Cancer. 2009, 8: 81-95. 10.1186/1476-4598-8-81.
Article
PubMed
PubMed Central
Google Scholar
Le Bras M, Borgne-Sanchez A, Touat Z, El Dein OS, Deniaud A, Maillier E, Lecellier G, Rebouillat D, Lemair C, Kroemer G, Jacotot E, Brenner C: Chemosensitization by knockdown of adeninenucleotide translocase-2. Cancer Res. 2006, 66: 9143-9152. 10.1158/0008-5472.CAN-05-4407.
Article
CAS
PubMed
Google Scholar
Chevrollier A, Loiseau D, Chabi B, Renier G, Donay O, Malthiery Y, Stepien G: ANT2 isoform required for cancer cell glycolysis. J Bioenerg Biomembr. 2005, 37: 307-316. 10.1007/s10863-005-8642-5.
Article
CAS
PubMed
Google Scholar
Luciakova K, Barath P, Poliakova D, Persson A, Nelson BD: Repression of the human adenine nucleotide translocase-2 gene in growth-arrested human diploid cells. J Biol Chem. 2003, 278: 30624-30633. 10.1074/jbc.M303530200.
Article
CAS
PubMed
Google Scholar
Xu W, Mimnaugh E, Rosser MF, Nicchitta C, Marcu M, Yarden Y, Neckers L: Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90. J Biol Chem. 2001, 276: 3702-3708. 10.1074/jbc.M006864200.
Article
CAS
PubMed
Google Scholar
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A: The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer. 2001, 8: 11-31. 10.1677/erc.0.0080011.
Article
CAS
PubMed
Google Scholar
Braun S, Schlimok G, Heumos I, Schaller G, Riethdorf L, Riethmuller G, Pantel K: ErbB2 overexpression on occult metastatic cells in bone marrow predicts poor clinical outcome of stage I-III breast cancer patients. Cancer Res. 2001, 61: 1890-1895.
CAS
PubMed
Google Scholar
Ono M, Kuwano M: Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs. Clin Cancer Res. 2006, 12: 7242-7251. 10.1158/1078-0432.CCR-06-0646.
Article
CAS
PubMed
Google Scholar
Scaltriti M, Baselga J: The epidermal growth factor receptor pathway: a model for targeted therapy. Clin Cancer Res. 2006, 12: 5268-5272. 10.1158/1078-0432.CCR-05-1554.
Article
CAS
PubMed
Google Scholar
Zhou BP, et al: HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-κB pathways. J Biol Chem. 2000, 275: 8027-8031. 10.1074/jbc.275.11.8027.
Article
CAS
PubMed
Google Scholar
Prenzel N, Fische OM, Streit S, Hart S, Ullrich A: The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer. 2001, 8: 11-31. 10.1677/erc.0.0080011.
Article
CAS
PubMed
Google Scholar
Mahmut Y, Gerhard C: EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev. 2009, 28: 15-33. 10.1007/s10555-008-9169-0.
Article
Google Scholar