Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007, 114 (2): 97-109. 10.1007/s00401-007-0243-4.
Article
PubMed
PubMed Central
Google Scholar
Nakada M, Nakada S, Demuth T, Tran NL, Hoelzinger DB, Berens ME: Molecular targets of glioma invasion. Cell Mol Life Sci. 2007, 64 (4): 458-478. 10.1007/s00018-007-6342-5.
Article
CAS
PubMed
Google Scholar
Davis FG, Freels S, Grutsch J, Barlas S, Brem S: Survival rates in patients with primary malignant brain tumors stratified by patient age and tumor histological type: an analysis based on Surveillance, Epidemiology, and End Results (SEER) data, 1973-1991. J Neurosurg. 1998, 88 (1): 1-10. 10.3171/jns.1998.88.1.0001.
Article
CAS
PubMed
Google Scholar
Mangiola A, Lama G, Giannitelli C, De Bonis P, Anile C, Lauriola L, La Torre G, Sabatino G, Maira G, Jhanwar-Uniyal M, et al: Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications. Clin Cancer Res. 2007, 13 (23): 6970-6977. 10.1158/1078-0432.CCR-07-1229.
Article
CAS
PubMed
Google Scholar
Drappatz J, Norden AD, Wen PY: Therapeutic strategies for inhibiting invasion in glioblastoma. Expert Rev Neurother. 2009, 9 (4): 519-534. 10.1586/ern.09.10.
Article
PubMed
Google Scholar
Wrensch M, Minn Y, Chew T, Bondy M, Berger MS: Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol. 2002, 4 (4): 278-299. 10.1215/15228517-4-4-278.
PubMed
PubMed Central
Google Scholar
Chen P, Wiencke J, Aldape K, Kesler-Diaz A, Miike R, Kelsey K, Lee M, Liu J, Wrensch M: Association of an ERCC1 polymorphism with adult-onset glioma. Cancer Epidemiol Biomarkers Prev. 2000, 9 (8): 843-847.
CAS
PubMed
Google Scholar
Cohen S: Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J Biol Chem. 1962, 237: 1555-1562.
CAS
PubMed
Google Scholar
Morton CC, Byers MG, Nakai H, Bell GI, Shows TB: Human genes for insulin-like growth factors I and II and epidermal growth factor are located on 12q22----q24.1, 11p15, and 4q25----q27, respectively. Cytogenet Cell Genet. 1986, 41 (4): 245-249. 10.1159/000132237.
Article
CAS
PubMed
Google Scholar
Carpenter G, Cohen S: Epidermal growth factor. Annu Rev Biochem. 1979, 48: 193-216. 10.1146/annurev.bi.48.070179.001205.
Article
CAS
PubMed
Google Scholar
Wong RW, Guillaud L: The role of epidermal growth factor and its receptors in mammalian CNS. Cytokine Growth Factor Rev. 2004, 15 (2-3): 147-156. 10.1016/j.cytogfr.2004.01.004.
Article
CAS
PubMed
Google Scholar
Nicholas MK, Lukas RV, Jafri NF, Faoro L, Salgia R: Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas. Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. 2006, 12 (24): 7261-7270.
Article
CAS
Google Scholar
Bello L: Urinary epidermal growth factor (EGF) levels and epidermal growth factor receptor (EGF-R) expression in human cerebral tumors. Clinical considerations. J Neurosurg Sci. 1996, 40 (3-4): 167-182.
CAS
PubMed
Google Scholar
Shahbazi M, Pravica V, Nasreen N, Fakhoury H, Fryer AA, Strange RC, Hutchinson PE, Osborne JE, Lear JT, Smith AG, et al: Association between functional polymorphism in EGF gene and malignant melanoma. Lancet. 2002, 359 (9304): 397-401. 10.1016/S0140-6736(02)07600-6.
Article
CAS
PubMed
Google Scholar
Vishnoi M, Pandey SN, Modi DR, Kumar A, Mittal B: Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer. Hum Immunol. 2008, 69 (6): 360-367. 10.1016/j.humimm.2008.04.004.
Article
CAS
PubMed
Google Scholar
Watanabe Y, Fukui N, Muratake T, Kaneko N, Someya T: No association of EGF polymorphism with schizophrenia in a Japanese population. Neuroreport. 2005, 16 (4): 403-405. 10.1097/00001756-200503150-00019.
Article
CAS
PubMed
Google Scholar
Lim YJ, Kim JW, Song JY, Hong MS, Jin SY, Yoon SH, Park HJ, Choe BK, Lee JJ, Yim SV, et al: Epidermal growth factor gene polymorphism is different between schizophrenia and lung cancer patients in Korean population. Neurosci Lett. 2005, 374 (3): 157-160. 10.1016/j.neulet.2004.10.055.
Article
CAS
PubMed
Google Scholar
Goto Y, Ando T, Goto H, Hamajima N: No association between EGF gene polymorphism and gastric cancer. Cancer Epidemiol Biomarkers Prev. 2005, 14 (10): 2454-2456. 10.1158/1055-9965.EPI-05-0401.
Article
CAS
PubMed
Google Scholar
James MR, Hayward NK, Dumenil T, Montgomery GW, Martin NG, Duffy DL: Epidermal growth factor gene (EGF) polymorphism and risk of melanocytic neoplasia. J Invest Dermatol. 2004, 123 (4): 760-762. 10.1111/j.0022-202X.2004.23305.x.
Article
CAS
PubMed
Google Scholar
Costa BM, Ferreira P, Costa S, Canedo P, Oliveira P, Silva A, Pardal F, Suriano G, Machado JC, Lopes JM, et al: Association between functional EGF+61 polymorphism and glioma risk. Clin Cancer Res. 2007, 13 (9): 2621-2626. 10.1158/1078-0432.CCR-06-2606.
Article
CAS
PubMed
Google Scholar
Vauleon E, Auger N, Benouaich-Amiel A, Laigle-Donadey F, Kaloshi G, Lejeune J, Delattre JY, Thillet J, Sanson M: The 61 A/G EGF polymorphism is functional but is neither a prognostic marker nor a risk factor for glioblastoma. Cancer Genet Cytogenet. 2007, 172 (1): 33-37. 10.1016/j.cancergencyto.2006.07.013.
Article
CAS
PubMed
Google Scholar
Liu Y, Zhang H, Zhou K, Chen L, Xu Z, Zhong Y, Liu H, Li R, Shugart YY, Wei Q, et al: Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma. Carcinogenesis. 2007, 28 (9): 1906-1913. 10.1093/carcin/bgm073.
Article
CAS
PubMed
Google Scholar
Hawkins DM: The problem of overfitting. J Chem Inf Comput Sci. 2004, 44 (1): 1-12.
Article
CAS
PubMed
Google Scholar
Ron E, Modan B, Boice JD, Alfandary E, Stovall M, Chetrit A, Katz L: Tumors of the brain and nervous system after radiotherapy in childhood. N Engl J Med. 1988, 319 (16): 1033-1039.
Article
CAS
PubMed
Google Scholar
Jorissen RN, Walker F, Pouliot N, Garrett TP, Ward CW, Burgess AW: Epidermal growth factor receptor: mechanisms of activation and signalling. Exp Cell Res. 2003, 284 (1): 31-53. 10.1016/S0014-4827(02)00098-8.
Article
CAS
PubMed
Google Scholar
Pastore S, Mascia F, Mariani V, Girolomoni G: The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol. 2008, 128 (6): 1365-1374. 10.1038/sj.jid.5701184.
Article
CAS
PubMed
Google Scholar
Bhowmick DA, Zhuang Z, Wait SD, Weil RJ: A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease. Cancer Research. 2004, 64 (4): 1220-1223. 10.1158/0008-5472.CAN-03-3137.
Article
CAS
PubMed
Google Scholar
Sauter G, Maeda T, Waldman FM, Davis RL, Feuerstein BG: Patterns of epidermal growth factor receptor amplification in malignant gliomas. Am J Pathol. 1996, 148 (4): 1047-1053.
CAS
PubMed
PubMed Central
Google Scholar
Chakravarti A, Delaney MA, Noll E, Black PM, Loeffler JS, Muzikansky A, Dyson NJ: Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas. Clin Cancer Res. 2001, 7 (8): 2387-2395.
CAS
PubMed
Google Scholar
Tanabe KK, Lemoine A, Finkelstein DM, Kawasaki H, Fujii T, Chung RT, Lauwers GY, Kulu Y, Muzikansky A, Kuruppu D, et al: Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis. JAMA. 2008, 299 (1): 53-60. 10.1001/jama.2007.65.
Article
CAS
PubMed
Google Scholar
Kang S, Kim JW, Park NH, Song YS, Park SY, Kang SB, Lee HP: Epidermal growth factor 61 A/G polymorphism and uterine cervical cancer. International Journal Of Gynecological Cancer: Official Journal Of The International Gynecological Cancer Society. 2007, 17 (2): 492-496.
Article
CAS
Google Scholar
Liu X, Li L, Chen X, Wang X, Mu L, Li Y, Xu Q, Xie Q, Lu F: No association between EGF +61 A/G polymorphism and increased risk of glioma. Int J Biol Markers. 2009, 24 (2): 77-82.
CAS
PubMed
Google Scholar
Vishnoi M, Pandey SN, Modi DR, Kumar A, Mittal B: Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer. Hum Immunol. 2008, 69 (6): 360-367. 10.1016/j.humimm.2008.04.004.
Article
CAS
PubMed
Google Scholar
Goto Y, Ando T, Goto H, Hamajima N: No association between EGF gene polymorphism and gastric cancer. Cancer Epidemiology, Biomarkers & Prevention: A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology. 2005, 14 (10): 2454-2456.
Article
CAS
Google Scholar
Kang HG, Choi JE, Lee WK, Kam S, Cha SI, Kim CH, Jung TH, Park JY: +61A>G polymorphism in the EGF gene does not increase the risk of lung cancer. Respirology. 2007, 12 (6): 902-905. 10.1111/j.1440-1843.2007.01152.x.
Article
PubMed
Google Scholar
Gao LB, Wei YS, Zhou B, Wang YY, Liang WB, Li C, Li Y, Bai P, Fang WL, Xue H, et al: No association between epidermal growth factor and epidermal growth factor receptor polymorphisms and nasopharyngeal carcinoma. Cancer Genet Cytogenet. 2008, 185 (2): 69-73. 10.1016/j.cancergencyto.2008.04.019.
Article
CAS
PubMed
Google Scholar
Araujo AP, Ribeiro R, Pinto D, Pereira D, Sousa B, Mauricio J, Lopes C, Medeiros R: Epidermal growth factor genetic variation, breast cancer risk, and waiting time to onset of disease. DNA Cell Biol. 2009, 28 (5): 265-269. 10.1089/dna.2008.0823.
Article
CAS
PubMed
Google Scholar
Rosenthal N, Schwartz RS: In search of perverse polymorphisms. N Engl J Med. 1998, 338 (2): 122-124. 10.1056/NEJM199801083380210.
Article
CAS
PubMed
Google Scholar
Costa BM, Ferreira P, Costa S, Canedo P, Oliveira P, Silva A, Pardal F, Suriano G, Machado JC, Lopes JM, et al: Association between functional EGF+61 polymorphism and glioma risk. Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. 2007, 13 (9): 2621-2626.
Article
CAS
Google Scholar
Long AD, Langley CH: The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res. 1999, 9 (8): 720-731.
CAS
PubMed
PubMed Central
Google Scholar
Lanuti M, Liu G, Goodwin JM, Zhai R, Fuchs BC, Asomaning K, Su L, Nishioka NS, Tanabe KK, Christiani DC: A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome. Clin Cancer Res. 2008, 14 (10): 3216-3222. 10.1158/1078-0432.CCR-07-4932.
Article
CAS
PubMed
PubMed Central
Google Scholar
Niklinski J, Niklinska W, Chyczewski L, Becker HD, Pluygers E: Molecular genetic abnormalities in premalignant lung lesions: biological and clinical implications. Eur J Cancer Prev. 2001, 10 (3): 213-226. 10.1097/00008469-200106000-00004.
Article
CAS
PubMed
Google Scholar
Shibata T, Hanada S, Kokubu A, Matsuno Y, Asamura H, Ohta T, Sakamoto M, Hirohashi S: Gene expression profiling of epidermal growth factor receptor/KRAS pathway activation in lung adenocarcinoma. Cancer Sci. 2007, 98 (7): 985-991. 10.1111/j.1349-7006.2007.00483.x.
Article
CAS
PubMed
Google Scholar
Holick CN, Giovannucci EL, Rosner B, Stampfer MJ, Michaud DS: Prospective study of cigarette smoking and adult glioma: dosage, duration, and latency. Neuro Oncol. 2007, 9 (3): 326-334. 10.1215/15228517-2007-005.
Article
PubMed
PubMed Central
Google Scholar
Zheng T, Cantor KP, Zhang Y, Chiu BC, Lynch CF: Risk of brain glioma not associated with cigarette smoking or use of other tobacco products in Iowa. Cancer Epidemiol Biomarkers Prev. 2001, 10 (4): 413-414.
CAS
PubMed
Google Scholar
Zhou W, Liu G, Park S, Wang Z, Wain JC, Lynch TJ, Su L, Christiani DC: Gene-smoking interaction associations for the ERCC1 polymorphisms in the risk of lung cancer. Cancer Epidemiol Biomarkers Prev. 2005, 14 (2): 491-496. 10.1158/1055-9965.EPI-04-0612.
Article
CAS
PubMed
Google Scholar
Cui L, Pan XM, Ma CF, Shang-Guan J, Yu HB, Chen GX, Wang J: Association Between Epidermal Growth Factor Polymorphism and Esophageal Squamous Cell Carcinoma Susceptibility. Dig Dis Sci. 2010, 55: 40-5. 10.1007/s10620-008-0700-5.
Article
CAS
PubMed
Google Scholar
Jin G, Miao R, Deng Y, Hu Z, Zhou Y, Tan Y, Wang J, Hua Z, Ding W, Wang L, et al: Variant genotypes and haplotypes of the epidermal growth factor gene promoter are associated with a decreased risk of gastric cancer in a high-risk Chinese population. Cancer Sci. 2007, 98 (6): 864-868. 10.1111/j.1349-7006.2007.00463.x.
Article
CAS
PubMed
Google Scholar
Gao LB, Wei YS, Zhou B, Wang YY, Liang WB, Li C, Li Y, Bai P, Fang WL, Xue H, et al: No association between epidermal growth factor and epidermal growth factor receptor polymorphisms and nasopharyngeal carcinoma. Cancer Genet Cytogenet. 2008, 185 (2): 69-73. 10.1016/j.cancergencyto.2008.04.019.
Article
CAS
PubMed
Google Scholar
Li Y, Xie Q, Lu F, Zhao J, Mao P, Li Z, Liu S, Zhuang H: Association between epidermal growth factor 61A/G polymorphism and hepatocellular carcinoma susceptibility in Chinese patients. Liver Int. 2009, 30 (1): 112-8. 10.1111/j.1478-3231.2009.02134.x.
Article
PubMed
Google Scholar
Wang Y, Tian T, Hu Z, Tang J, Wang S, Wang X, Qin J, Huo X, Gao J, Ke Q, et al: EGF promoter SNPs, plasma EGF levels and risk of breast cancer in Chinese women. Breast Cancer Res Treat. 2008, 111 (2): 321-327. 10.1007/s10549-007-9784-4.
Article
CAS
PubMed
Google Scholar
Spindler KL, Nielsen JN, Ornskov D, Brandslund I, Jakobsen A: Epidermal growth factor (EGF) A61G polymorphism and EGF gene expression in normal colon tissue from patients with colorectal cancer. Acta Oncol. 2007, 46 (8): 1113-1117. 10.1080/02841860701338853.
Article
CAS
PubMed
Google Scholar
Randerson-Moor JA, Gaut R, Turner F, Whitaker L, Barrett JH, Silva Idos S, Swerdlow A, Bishop DT, Bishop JA: The relationship between the epidermal growth factor (EGF) 5'UTR variant A61G and melanoma/nevus susceptibility. J Invest Dermatol. 2004, 123 (4): 755-759. 10.1111/j.0022-202X.2004.23304.x.
Article
CAS
PubMed
Google Scholar
Amend KL, Elder JT, Tomsho LP, Bonner JD, Johnson TM, Schwartz J, Berwick M, Gruber SB: EGF gene polymorphism and the risk of incident primary melanoma. Cancer Res. 2004, 64 (8): 2668-2672. 10.1158/0008-5472.CAN-03-3855.
Article
CAS
PubMed
Google Scholar
Lanuti M, Liu G, Goodwin JM, Zhai R, Fuchs BC, Asomaning K, Su L, Nishioka NS, Tanabe KK, Christiani DC: A functional epidermal growth factor (EGF) polymorphism, EGF serum levels, and esophageal adenocarcinoma risk and outcome. Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. 2008, 14 (10): 3216-3222.
Article
CAS
Google Scholar
Casula M, Alaibac M, Pizzichetta MA, Bono R, Ascierto PA, Stanganelli I, Canzanella S, Palomba G, Zattra E, Palmieri G: Role of the EGF +61A>G polymorphism in melanoma pathogenesis: an experience on a large series of Italian cases and controls. BMC Dermatol. 2009, 9: 7-10.1186/1471-5945-9-7.
Article
PubMed
PubMed Central
Google Scholar
Araujo AP, Ribeiro R, Pereira D, Pinto D, Sousa B, Catarino R, Medeiros R: Ovarian cancer and genetic susceptibility: association of A61G polymorphism in the EGF gene. Exp Biol Med (Maywood). 2009, 234 (3): 241-245. 10.3181/0805-RM-146.
Article
CAS
Google Scholar
Pinto GR, Yoshioka FK, Clara CA, Santos MJ, Almeida JR, Burbano RR, Rey JA, Casartelli C: Association study of an epidermal growth factor gene functional polymorphism with the risk and prognosis of gliomas in Brazil. Int J Biol Markers. 2009, 24 (4): 277-281.
CAS
PubMed
Google Scholar