Table 5 Stratified analysis of association by Smoking status between the genotypes (alleles) and risk of glioma

Never

genotype

GG

148/239

1(Reference)

1(Reference)

1(Reference)

GA

193/180

0.0002

1.73(1.30-2.31)

0.0002

1.73(1.29-2.31)

0.0002

1.72(1.29-2.30)

AA

40/35

0.016

1.85(1.12-3.04)

0.018

1.82(1.11-3.00)

0.020

1.81(1.10-2.99)

Genetic model

additive

0.0002

1.50(1.21-1.86)

0.0003

1.49(1.20-1.85)

0.0003

1.49(1.20-1.84)

Allele

G

489/658

1(Reference)

#

A

273/250

0.0003

1.47(1.19-1.81)

Ever

genotype

GG

31/55

1(Reference)

1(Reference)

1(Reference)

GA

35/45

0.311

1.38(0.74-2.57)

0.395

1.32(0.70-2.51)

0.527

1.23(0.64-2.36)

AA

6/8

0.625

1.33(0.42-4.19)

0.905

1.07(0.34-3.43)

0.941

1.05(0.32-3.37)

Genetic model

additive

0.359

1.25(0.78-2.00)

0.572

1.15(0.78-1.87)

0.684

1.11(0.68-1.81)

Allele

G

97/155

1(Reference)

#

A

47/61

0.373

1.23(0.78-1.95)

Current

genotype

GG

68/70

1(Reference)

1(Reference)

1(Reference)

GA

45/51

0.718

0.91(0.54-1.53)

0.874

0.96(0.56-1.63)

0.878

0.96(0.56-1.63)

AA

16/7

0.077

2.35(0.91-6.08)

0.092

2.28(0.88-5.96)

0.090

2.29(0.88-5.99)

Genetic model

additive

0.275

1.23(0.85-1.80)

0.254

1.25(0.85-1.83)

0.249

1.25(0.85-1.84)

Allele

G

181/191

1(Reference)

#

A

77/65

0.259

1.25(0.85-1.84)