Table 7 Stratified analysis of association by WHO between the genotypes (alleles) and risk of glioma

I

GG

25/366

1(Reference)

1(Reference)

1(Reference)

GA

28/276

0.167

1.49(0.85-2.60)

0.160

1.50(0.85-2.64)

0.041

1.92(1.03-3.61)

AA

7/51

0.123

2.01(0.83-4.88)

0.102

2.11(0.86-5.16)

0.062

2.55(0.95-6.84)

additive

0.071

1.44(0.97-2.14)

0.060

1.47(0.98-2.19)

0.018

1.69(1.09-2.61)

G

78/1008

1(Reference)

#

A

42/378

0.071

1.44(0.97-2.13)

II

GG

103/366

1(Reference)

1(Reference)

1(Reference)

GA

109/276

0.033

1.40(1.03-1.92)

0.036

1.40(1.02-1.91)

0.013

1.52(1.09-2.13)

AA

22/51

0.125

1.53(0.89-2.65)

0.128

1.53(0.89-2.64)

0.098

1.63(0.91-2.92)

additive

0.024

1.30(1.04-1.64)

0.026

1.30(1.03-1.63)

0.012

1.37(1.07-1.75)

G

315/1008

1(Reference)

#

A

153/378

0.025

1.30(1.03-1.62)

III

GG

62/366

0.484

1(Reference)

1(Reference)

1(Reference)

GA

49/276

0.821

1.05(0.70-1.57)

0.806

1.05(0.70-1.58)

0.583

1.13(0.74-1.73)

AA

5/51

0.263

0.58(0.22-1.51)

0.264

0.58(0.22-1.51)

0.276

0.56(0.19-1.60)

additive

0.555

0.91(0.66-1.25)

0.564

0.91(0.66-1.256)

0.726

0.94(0.67-1.32)

G

173/1008

1(Reference)

#

A

59/378

0.559

0.91(0.66-1.25)

IV

GG

108/366

1(Reference)

1(Reference)

1(Reference)

GA

119/276

0.014

1.46(1.08-1.98)

0.006

1.55(1.13-2.12)

0.006

1.59(1.14-2.22)

AA

35/51

0.001

2.33(1.44-3.76)

0.001

2.32(1.42-3.81)

0.0002

2.65(1.58-4.45)

additive

0.0002

1.50(1.21-1.87)

0.0002

1.53(1.23-1.91)

<0.001

1.62(1.28-2.04)

G

335/1008

1(Reference)

#

A

189/378

0.0002

1.50(1.22-1.86)

I+ II

GG

128/366

1(Reference)

1(Reference)

1(Reference)

GA

137/276

0.017

1.42(1.07-1.89)

0.019

1.41(1.06-1.89)

0.003

1.59(1.17-2.16)

AA

29/51

0.056

1.63(0.99-2.68)

0.057

1.63(0.99-2.68)

0.034

1.78(1.04-3.03)

additive

0.008

1.33(1.08-1.64)

0.009

1.33(1.07-1.64)

0.002

1.43(1.14-1.79)

G

393/1008

1(Reference)

#

A

195/378

0.008

1.32(1.07-1.63)

III+ IV

GG

170/366

1(Reference)

1(Reference)

1(Reference)

GA

168/276

0.045

1.31(1.01-1.71)

0.025

1.36(1.04-1.78)

0.015

1.42(1.07-1.88)

AA

40/51

0.023

1.69(1.07-2.65)

0.033

1.65(1.04-2.61)

0.016

1.79(1.11-2.89)

additive

0.007

1.30(1.07-1.58)

0.007

1.31(1.08-1.60)

0.003

1.37(1.11-1.68)

G

508/1008

1(Reference)

#

A

248/378

0.007

1.30(1.07-1.58)