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  1. High risk type human papilloma viruses (HR-HPV) induce carcinomas of the uterine cervix by expressing viral oncogenes E6 and E7. Oncogene E7 of HR-HPV disrupts the pRb/E2F interaction, which negatively regulat...

    Authors: Tatiana A Ivanova, Daria A Golovina, Larisa E Zavalishina, Galina M Volgareva, Alexey N Katargin, Yulia Y Andreeva, Georgy A Frank, Fjodor L Kisseljov and Natalia P Kisseljova
    Citation: BMC Cancer 2007 7:47
  2. Breast cancer is one of the most extensively studied cancers and its genetic basis is well established. Dermatoglyphic traits are formed under genetic control early in development but may be affected by enviro...

    Authors: Chintamani, Rohan Khandelwal, Aliza Mittal, Sai Saijanani, Amita Tuteja, Anju Bansal, Dinesh Bhatnagar and Sunita Saxena
    Citation: BMC Cancer 2007 7:44
  3. Cancer-cachexia induces a variety of metabolic disorders on protein turnorver, decreasing protein synthesis and increasing protein degradation. Controversly, insulin, other hormones, and branched-chain amino a...

    Authors: Gislaine Ventrucci, Maria Alice R Mello and Maria Cristina C Gomes-Marcondes
    Citation: BMC Cancer 2007 7:42
  4. The disappointing results of surgical therapy alone of ductal pancreatic cancer can only be improved using multimodal approaches. In contrast to adjuvant therapy, neoadjuvant chemoradiation is able to facilita...

    Authors: Thomas B Brunner, Gerhard G Grabenbauer, Thomas Meyer, Henriette Golcher, Rolf Sauer and Werner Hohenberger
    Citation: BMC Cancer 2007 7:41
  5. The study was designed to investigate immunocompetence in relation to cancer progression in rat and to assess the effect of the traditional Chinese anti-cancer medicine, "Shenyang" prescription, on immunity.

    Authors: Canhua Jiang, Dongxia Ye, Weiliu Qiu, Xiuli Zhang, Zhiyuan Zhang, Di He, Ping Zhang and Wantao Chen
    Citation: BMC Cancer 2007 7:40
  6. Current histo-pathological prognostic factors are not very helpful in predicting the clinical outcome of breast cancer due to the disease's heterogeneity. Molecular profiling using a large panel of genes could...

    Authors: Maïa Chanrion, Hélène Fontaine, Carmen Rodriguez, Vincent Negre, Frédéric Bibeau, Charles Theillet, Alain Hénaut and Jean-Marie Darbon
    Citation: BMC Cancer 2007 7:39
  7. Primary small cell carcinoma (SCC) of the esophagus is a rare and aggressive tumor with poor prognosis. In this study, we report the clinicopathological characteristics of 21 cases of small cell carcinoma of t...

    Authors: Jing-Ping Yun, Mei-Fang Zhang, Jin-Hui Hou, Qiu-Hong Tian, Jia Fu, Xiao-Man Liang, Qiu-Liang Wu and Tie-Hua Rong
    Citation: BMC Cancer 2007 7:38
  8. Shared Pathology Informatics Network (SPIN) is a tissue resource initiative that utilizes clinical reports of the vast amount of paraffin-embedded tissues routinely stored by medical centers. SPIN has an infor...

    Authors: Ashokkumar A Patel, Dilipkumar Gupta, David Seligson, Eyas M Hattab, Ulysses J Balis, Thomas M Ulbright, Isaac S Kohane, Jules J Berman, John R Gilbertson, Sarah Dry, Osvaldo Schirripa, Hong Yu, Michael J Becich and Anil V Parwani
    Citation: BMC Cancer 2007 7:37
  9. Neoadjuvant chemotherapy has been considered the standard care in locally advanced breast cancer. However, about 20% of the patients do not benefit from this clinical treatment and, predictive factors of respo...

    Authors: Daniel G Tiezzi, Jurandyr M Andrade, Alfredo Ribeiro-Silva, Fábio E Zola, Heitor RC Marana and Marcelo G Tiezzi
    Citation: BMC Cancer 2007 7:36
  10. The inability of cancer cells to present antigen on the cell surface via MHC class I molecules is one of the mechanisms by which tumor cells evade anti-tumor immunity. Alterations of Jak-STAT components of int...

    Authors: Teresa Rodríguez, Rosa Méndez, Ana Del Campo, Pilar Jiménez, Natalia Aptsiauri, Federico Garrido and Francisco Ruiz-Cabello
    Citation: BMC Cancer 2007 7:34
  11. Abnormalities in Human Leukocyte Antigen (HLA) class I expression are common in colorectal cancer. Since HLA expression is required to activate tumor antigen-specific cytotoxic T-lymphocytes (CTL), HLA class I...

    Authors: Jan Willem F Dierssen, Noel FCC de Miranda, Soldano Ferrone, Marjo van Puijenbroek, Cees J Cornelisse, Gert Jan Fleuren, Tom van Wezel and Hans Morreau
    Citation: BMC Cancer 2007 7:33
  12. In general, prognosis and impact of prognostic/predictive factors are assessed with Kaplan-Meier plots and/or the Cox proportional hazard model. There might be substantive differences from the results using th...

    Authors: Patricia Tai, Judith-Anne W Chapman, Edward Yu, Dennie Jones, Changhong Yu, Fei Yuan and Lee Sang-Joon
    Citation: BMC Cancer 2007 7:31
  13. The STAT (Signal Transducers and Activators of Transcription) transcription factor family mediates cellular responses to a wide range of cytokines. Activated STATs (particularly STAT3) are found in a range of ...

    Authors: James R Matthews, Susan MR Watson, Maxine CL Tevendale, Christine J Watson and Alan R Clarke
    Citation: BMC Cancer 2007 7:29
  14. Hepatocellular carcinoma is the most common cause of primary liver neoplasms and is one of the main causes of death in patients with liver cirrhosis. High Alpha fetoprotein serum levels have been found in 60–7...

    Authors: Oscar Arrieta, Bernardo Cacho, Daniela Morales-Espinosa, Ana Ruelas-Villavicencio, Diana Flores-Estrada and Norma Hernández-Pedro
    Citation: BMC Cancer 2007 7:28
  15. Authors: Lucely Cetina, Alicia Garcia, Jesús Uribe, Myrna Candelaria, Carlos Lopez-Graniel, Aaron Gonzalez, David Cantu, Lesbia Rivera, Jose Hinojosa and Alfonso Dueñas-Gonzalez
    Citation: BMC Cancer 2007 7(Suppl 1):A19

    This article is part of a Supplement: Volume 7 Supplement 1

  16. Authors: Lucely Cetina, Alicia Garcia-Arias, Maria de Jesus Uribe, Alma Astorga, Myrna Candelaria, Aida Mota, Roque Guadarrama, Lesbia Rivera, Jose Hinojosa and Alfonso Dueñas-Gonzalez
    Citation: BMC Cancer 2007 7(Suppl 1):A17

    This article is part of a Supplement: Volume 7 Supplement 1

  17. Authors: María de Lourdes Mora-García, Alfonso Duenas-González, Jorge Hernández-Montes, Benny Weiss-Steider, Edelmiro Santiago-Osorio, Vianney Francisco Ortíz-Navarrete, Víctor Hugo Rosales, David Cantú, Marcela Lizano-Soberón and Alberto Monroy-García
    Citation: BMC Cancer 2007 7(Suppl 1):A12

    This article is part of a Supplement: Volume 7 Supplement 1

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