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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Wilms’ tumour gene 1 (WT1) is clearly recognized as a tumour promoter in diversiform of human malignancies. Nevertheless, knowledge of its expression, functions and potential molecular mechanisms in non-small ...

    Authors: Xuebing Li, Wenzhe An, Hongli Pan, Yaguang Fan, Hua Huang, Yixuan Wang, Wang Shen, Lingling Zu, Fanrong Meng and Xuexia Zhou
    Citation: BMC Cancer 2023 23:824
    Content type: Research Published on:

    The Correction to this article has been published in BMC Cancer 2023 23:909

  3. Lung cancer is the leading cause of cancer deaths worldwide. Surgery, radiotherapy at conventional and high dose and chemotherapy are the mainstay for lung cancer treatment. Insufficient migration and activati...

    Authors: Seyer Safi, Philipp Beckhove, Arne Warth, Axel Benner, Falk Roeder, Stefan Rieken, Juergen Debus, Hendrik Dienemann, Hans Hoffmann and Peter E. Huber
    Citation: BMC Cancer 2015 15:988
    Content type: Study protocol Published on:

  4. Epithelial–mesenchymal transition (EMT) plays a significant role in tumor progression and invasion. Snail is a known regulator of EMT in various malignant tumors. This study investigated the role of Snail in g...

    Authors: Na Ri Shin, Eun Hui Jeong, Chang In Choi, Hyun Jung Moon, Chae Hwa Kwon, In Sun Chu, Gwang Ha Kim, Tae Yong Jeon, Dae Hwan Kim, Jae Hyuk Lee and Do Youn Park
    Citation: BMC Cancer 2012 12:521
    Content type: Research article Published on:

  5. Recently it has been recognized that stromal markers could be used as a clinically relevant biomarker for therapy response and prognosis. Here, we report on a serum marker for stromal activation, A Disintegrin...

    Authors: Sanne ten Hoorn, Cynthia Waasdorp, Martijn G. H. van Oijen, Helene Damhofer, Anne Trinh, Lan Zhao, Lisanne J. H. Smits, Sanne Bootsma, Gabi W. van Pelt, Wilma E. Mesker, Linda Mol, Kaitlyn K. H. Goey, Miriam Koopman, Jan Paul Medema, Jurriaan B. Tuynman, Inti Zlobec…
    Citation: BMC Cancer 2022 22:394
    Content type: Research Published on:

  6. CD133 (prominin-1) is widely believed to be a cancer stem cell marker in various solid tumor types, and CD133 has been correlated with tumor-initiating capacity. Recently, the nuclear location of CD133 express...

    Authors: Yao-Li Chen, Ping-Yi Lin, Ying-Zi Ming, Wei-Chieh Huang, Rong-Fu Chen, Po-Ming Chen and Pei-Yi Chu
    Citation: BMC Cancer 2017 17:474
    Content type: Research article Published on:

  7. Chemotherapy-induced neutropenia (CIN) has been demonstrated to be a prognostic factor in several cancer conditions. We previously found a significant prognostic value of CIN on overall survival (OS), in a poo...

    Authors: Piera Gargiulo, Laura Arenare, Cesare Gridelli, Alessandro Morabito, Fortunato Ciardiello, Vittorio Gebbia, Paolo Maione, Alessia Spagnuolo, Giuliano Palumbo, Giovanna Esposito, Carminia Maria Della Corte, Floriana Morgillo, Gianfranco Mancuso, Raimondo Di Liello, Adriano Gravina, Clorinda Schettino…
    Citation: BMC Cancer 2021 21:549
    Content type: Research Published on:

  8. Comorbidity has been established as one of the important predictors of poor prognosis in lung cancer. In this study, we analyzed the prevalence of main comorbidities and its association with hospital readmissi...

    Authors: Dawei Zhu, Ruoxi Ding, Yong Ma, Zhishui Chen, Xuefeng Shi and Ping He
    Citation: BMC Cancer 2021 21:557
    Content type: Research article Published on:

  9. This study aimed to conduct a comprehensive analysis, evaluating the prognostic significance of the baseline Advanced Lung Cancer Inflammation Index (ALI) and Gustave Roussy Immune (GRIm) Score in patients und...

    Authors: Hao Jiang, Borui Li, Min Wu, Qimei Wang and Yijin Li
    Citation: BMC Cancer 2024 24:428
    Content type: Research Published on:

  10. The lymphocytes played an important role in the natural history of cancer. The aim of this study was to explore the prognostic value of lymphocyte count and percentage for survival in advanced cancer patients ...

    Authors: Weiwei Zhao, Peng Wang, Huixun Jia, Menglei Chen, Xiaoli Gu, Minghui Liu, Zhe Zhang, Wenwu Cheng and Zhenyu Wu
    Citation: BMC Cancer 2017 17:514
    Content type: Research article Published on:

  11. Fatty acid (FA) metabolism is considered the emerging cause of tumor development and metastasis, driving poor prognosis. Long non-coding RNAs (lncRNAs) are closely related to cancer progression and play import...

    Authors: Erbao Chen, Jing Yi, Jing Jiang, Zhilin Zou, Yuqian Mo, Qingqi Ren, Zewei Lin, Yi Lu, Jian Zhang and Jikui Liu
    Citation: BMC Cancer 2022 22:1037
    Content type: Research Published on:

  12. Six hypothetical health states for lung cancer or a related health state reflective of disease severity were developed: 1) Stage I, 2) Stage II, 3) Stage IIIa, 4) Stage IIIB, 5) Stage IV, and 6) Pulmonary nodule....

    Authors: Eun-Jung Kim, Minsu Ock, Kyu-pyo Kim, Nuri Hyun Jung, Hyeon-Jeong Lee, Seon-Ha Kim and Min-Woo Jo
    Citation: BMC Cancer 2018 18:1081
    Content type: Research article Published on:

  13. The goal of therapy for many patients with advanced stage malignancies, including those with metastatic gastric and esophageal cancers, is to extend overall survival while also maintaining quality of life. Aft...

    Authors: Xiaoyuan Ma, Eric Pierce, Harsh Anand, Natalie Aviles, Paul Kunk and Negin Alemazkoor
    Citation: BMC Cancer 2023 23:910
    Content type: Research Published on:

  14. Immune checkpoint inhibitors (ICIs) have been used to successfully treat primary liver cancer (PLC); however, identifying modifiable patient factors associated with therapeutic benefits is challenging. Obesity...

    Authors: Lu-shan Xiao, Rui-ning Li, Hao Cui, Chang Hong, Chao-yi Huang, Qi-mei Li, Cheng-yi Hu, Zhong-yi Dong, Hong-bo Zhu and Li Liu
    Citation: BMC Cancer 2022 22:737
    Content type: Research Published on:

  15. Raf-1 kinase inhibitor protein (RKIP) has been reported to negatively regulate signal kinases of major survival pathways. RKIP activity is modulated in part by phosphorylation on Serine 153 by protein kinase C...

    Authors: Sara Huerta-Yepez, Nam K Yoon, Angeles Hernandez-Cueto, Vei Mah, Clara M Rivera-Pazos, Devasis Chatterjee, Mario I Vega, Erin L Maresh, Steve Horvath, David Chia, Benjamin Bonavida and Lee Goodglick
    Citation: BMC Cancer 2011 11:259
    Content type: Research article Published on:

  16. The incidence of Human Papillomavirus (HPV) associated oropharyngeal cancer (OPC) is increasing. HPV-associated OPC appear to have better prognosis than HPV-negative OPC. The aim of this study was to robustly ...

    Authors: Mererid Evans, Robert Newcombe, Alison Fiander, James Powell, Martin Rolles, Selvam Thavaraj, Max Robinson and Ned Powell
    Citation: BMC Cancer 2013 13:220
    Content type: Research article Published on:

  17. Venous thromboembolism (VTE) is highly prevalent in cancer patients and can cause severe morbidity. VTE treatment is essential, but anticoagulation increases the risk of major bleeding. The purpose was to eval...

    Authors: Jennifer Howlett, Eric Benzenine, Jonathan Cottenet, Pascal Foucher, Philippe Fagnoni and Catherine Quantin
    Citation: BMC Cancer 2020 20:461
    Content type: Research article Published on:

  18. MEK1 (MAP2K1) and MEK2 (MAP2K2) are closely related dual-specificity protein kinases which function by phosphorylating both serine/threonine and tyrosine residues of their substrates ERK1 and ERK2, controlling...

    Authors: J. Gomez-Millan, B. Pajares, L. Perez-Villa, A. Carnero, M. Alvarez, V. De Luque, F. Rivas, J. M. Trigo, M. D. Toledo, E. Alba and J. A. Medina
    Citation: BMC Cancer 2016 16:829
    Content type: Research article Published on:

  19. The relationship of neutrophil/lymphocyte ratio (NLR) to prognosis of HER2-positive breast cancer (BC) is not well studied. We aimed to assess the prognostic role of NLR in HER2-positive BC patients treated wi...

    Authors: Nianhua Ding, Juan Huang, Ningsha Li, Jiaqi Yuan, Shouman Wang and Zhi Xiao
    Citation: BMC Cancer 2020 20:235
    Content type: Research article Published on:

  20. Tumor cell-monocyte interactions play crucial roles in shaping up the pro-tumorigenic phenotype and functional output of tumor-associated macrophages. Within the tumor microenvironment, such heterotypic cell–c...

    Authors: Asif Amin, Aabid Mustafa Koul, Umer Majeed Wani, Faizah Farooq, Basit Amin, Zubair Wani, Asif Lone, Ayub Qadri and Raies A. Qadri
    Citation: BMC Cancer 2023 23:926
    Content type: Research Published on:

  21. To evaluate the safety and effectiveness of computed tomography (CT)-guided radioactive 125I seeds brachytherapy (RISB) for lung oligometastases (LO) from colorectal cancer (CRC).

    Authors: Mengyao Song, Xueliang Zhou, Rongna Hou, Milan Sigdel, Yiming Liu, Chengzhi Zhang, Kaihao Xu, Xinwei Han and Dechao Jiao
    Citation: BMC Cancer 2024 24:265
    Content type: Research Published on:

  22. Systemic inflammation is crucial for the development and progression of cancers. The advanced lung cancer inflammation index (ALI) is considered to be a better indicator of systemic inflammation than current b...

    Authors: Lilong Zhang, Kailiang Zhao, Tianrui kuang, Kunpeng Wang, Dongqi Chai, Zhendong Qiu, Rongqiang Liu, Wenhong Deng and Weixing Wang
    Citation: BMC Cancer 2023 23:101
    Content type: Research Published on:

  23. Non-small cell cancer (NSCLC) patients with concomitant epidermal growth factor receptor (EGFR) and TP53 mutations have a poor prognosis with the treatment of tyrosine kinase inhibitors (TKIs), and may benefit...

    Authors: Haiyan Sun, Peng Ren, Yongzi Chen, Lan Lan, Zhuchen Yan, Yinli Yang, Bin Wang, Cong Wang, Yanwei Li, Ling Li, Yu Zhang, Yanyang Li, Zuolin Wang, Zhanyu Pan and Zhansheng Jiang
    Citation: BMC Cancer 2023 23:198
    Content type: Research Published on:

  24. Two mature microRNAs (miRNAs), hsa-miR-125a-3p and hsa-miR-125a-5p (collectively referred to as hsa-miR-125a-3p/5p), are derived from 3' and 5' ends of pre-miR-125a, respectively. Although impaired regulation ...

    Authors: Lili Jiang, Qin Huang, Siyang Zhang, Qingfu Zhang, Jihong Chang, Xueshan Qiu and Enhua Wang
    Citation: BMC Cancer 2010 10:318
    Content type: Research article Published on:

  25. Hepatocellular carcinoma (HCC) is one of the most common human cancers with poor prognosis in the world. HCC has become the second leading cause of cancer-related death in China. It is urgent to identify novel...

    Authors: Yuchen Qi, Yujing Zhang, Jianwen Li, Mengting Cai, Bo Zhang, Zhangtao Yu, Yuhang Li, Junkai Huang, Xu Chen, Yinghui Song and Sulai Liu
    Citation: BMC Cancer 2023 23:637
    Content type: Research Published on:

  26. Various cancer stem cell (CSC) biomarkers and the genes encoding them in head and neck squamous cell carcinoma (HNSCC) have been identified and evaluated. However, the validity of these factors in the prognosi...

    Authors: Su Il Kim, Seon Rang Woo, Joo Kyung Noh, Min Kyeong Lee, Young Chan Lee, Jung Woo Lee, Moonkyoo Kong, Seong-Gyu Ko and Young-Gyu Eun
    Citation: BMC Cancer 2022 22:1077
    Content type: Research Published on:

  27. The COVID-19 pandemic is predicted to significantly affect patients with lung cancer, owing to its rapid progression and high mortality. Studies on lung cancer diagnosis and treatment during an epidemic are la...

    Authors: Ji Young Park, Ye Jin Lee, Taehee Kim, Chang Youl Lee, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung and Seung Hun Jang
    Citation: BMC Cancer 2020 20:1040
    Content type: Research article Published on:

  28. Immigrants make up an important share of European populations which has led to a growing interest in research on migrants’ health. Many studies have assessed migrants’ cancer mortality patterns, yet few have s...

    Authors: Katrien Vanthomme, Michael Rosskamp, Harlinde De Schutter and Hadewijch Vandenheede
    Citation: BMC Cancer 2021 21:328
    Content type: Research article Published on:

  29. Lung cancer is the most common oncological cause of death in the Western world. Early diagnosis is critical for successful treatment. However, no effective screening methods exist. A promising approach could b...

    Authors: Charlotte Feil, Frank Staib, Martin R. Berger, Thorsten Stein, Irene Schmidtmann, Andreas Forster and Carl C. Schimanski
    Citation: BMC Cancer 2021 21:917
    Content type: Research Published on:

  30. Thyroid transcription factor (TTF)-1 expression is a diagnostic marker and a good prognostic indicator for lung adenocarcinoma. However, its good prognostic ability might be due to epidermal growth factor rece...

    Authors: Ji Young Park, Seung Hun Jang, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung, Jinwon Seo, Chang Youl Lee, Yousang Ko and Yong-Bum Park
    Citation: BMC Cancer 2019 19:574
    Content type: Research article Published on:

  31. Anxiety is a prevalent comorbidity in lung cancer (LC) patients associated with a decline in quality of life. Dehydroepiandrosterone (DHEA), a neuroactive steroid, levels rise in response to stress. Prior rese...

    Authors: Jia-Rong Wu, Vincent Chin -Hung Chen, Yu-Hung Fang, Ching-Chuan Hsieh and Shu-I Wu
    Citation: BMC Cancer 2024 24:476
    Content type: Research Published on:

  34. Osteopontin (OPN) and thrombospondin-1 (TSP-1) are extracellular matrix proteins secreted by stromal and tumor cells. These proteins appear to have a key role in the tumor microenvironment for cancer developme...

    Authors: Mathieu Rouanne, Julien Adam, Aïcha Goubar, Angélique Robin, Caroline Ohana, Emilie Louvet, Jiemin Cormier, Olaf Mercier, Peter Dorfmüller, Soly Fattal, Vincent Thomas de Montpreville, Thierry Lebret, Philippe Dartevelle, Elie Fadel, Benjamin Besse, Ken André Olaussen…
    Citation: BMC Cancer 2016 16:483
    Content type: Research article Published on:

  35. The prognosis of patients with NSCLC harboring oncogenic driver gene alterations, such as EGFR gene mutations or ALK fusion, has improved dramatically with the advent of corresponding molecularly targeted drugs. ...

    Authors: Shoko Sonobe Shimamura, Takehito Shukuya, Tetsuhiko Asao, Daisuke Hayakawa, Kana Kurokawa, Shiting Xu, Keita Miura, Yoichiro Mitsuishi, Ken Tajima, Rina Shibayama, Naoko Shimada, Fumiyuki Takahashi and Kazuhisa Takahashi
    Citation: BMC Cancer 2022 22:323
    Content type: Research Published on:

  36. The role of the PRDM5 in esophageal squamous cell carcinoma (ESCC) has not been revealed. This study investigated the relationship between PRDM5 expression and survival outcome in esophageal squamous cell carc...

    Authors: Jing Guo, Qiuxing Yang, Sheng Wei, Jingjing Shao, Tianye Zhao, Liyuan Guo, Jia Liu, Jia Chen and Gaoren Wang
    Citation: BMC Cancer 2022 22:745
    Content type: Research article Published on:

  37. Anaemia is highly prevalent in gastric cancer (GC) patients. The role of initial haemoglobin levels in predicting the prognosis of GC patients treated by chemotherapy has not been well determined. Our present ...

    Authors: Wen-Huan Li, Ji-Yu Zhang, Wen-Hui Liu and Xian-Xian Chen
    Citation: BMC Cancer 2020 20:414
    Content type: Research article Published on:

  38. Globally, endometrial cancer is the fourth most common malignant tumor in women and the number of women being diagnosed is increasing. Tumor progression is strongly related to the cell survival-promoting funct...

    Authors: Jun Zhang, Ziwei Wang, Rong Zhao, Lanfen An, Xing Zhou, Yingchao Zhao and Hongbo Wang
    Citation: BMC Cancer 2020 20:1030
    Content type: Research article Published on:

  39. Aquaporins (AQPs) have been recognized to promote tumor progression, invasion, and metastasis and are therefore recognized as promising targets for novel anti-cancer therapies. Potentially relevant AQPs in dis...

    Authors: Arne Warth, Thomas Muley, Michael Meister, Esther Herpel, Anita Pathil, Hans Hoffmann, Philipp A Schnabel, Christian Bender, Andreas Buness, Peter Schirmacher and Ruprecht Kuner
    Citation: BMC Cancer 2011 11:161
    Content type: Research article Published on:

  40. Gut microbiome has been linked to a regulatory role in cancer progression. However, whether broad-spectrum antibiotics (ATB) associated gut microbiome dysbiosis contributes to an impaired T cell immune functio...

    Authors: Ke Xu, Jixu Cai, Jun Xing, Xu Li, Beishou Wu, Zhuxian Zhu and Ziqiang Zhang
    Citation: BMC Cancer 2022 22:1182
    Content type: Research Published on:

  41. The metastasis-promoting protein S100A4 induces expression of ephrin-A1 and osteopontin in osteosarcoma cell lines. The aim of this study was to investigate S100A4-mediated stimulation of ephrin-A1 and osteopo...

    Authors: Ane Kongsgaard Rud, Marius Lund-Iversen, Gisle Berge, Odd Terje Brustugun, Steinar K Solberg, Gunhild M Mælandsmo and Kjetil Boye
    Citation: BMC Cancer 2012 12:333
    Content type: Research article Published on:

  43. Lung adenocarcinoma (LUAD) is a major subtype of lung cancer and closely associated with poor prognosis. N6-methyladenosine (m6A), one of the most predominant modifications in mRNAs, is found to participate in...

    Authors: Hao Zhou, Miaosen Zheng, Muqi Shi, Jinjie Wang, Zhanghao Huang, Haijian Zhang, Youlang Zhou and Jiahai Shi
    Citation: BMC Cancer 2021 21:938
    Content type: Research Published on:

  44. EGFR inhibitor and immunotherapy have been approved for adjuvant treatment in resectable non-small cell lung cancer (NSCLC). Limited reports of molecular and clinical characteristics as prognostic factors in N...

    Authors: T. Thamrongjirapat, D. Muntham, P. Incharoen, N. Trachu, P. Sae-Lim, N. Sarachai, K. Khiewngam, N. Monnamo, N. Kantathut, M. Ngodngamthaweesuk, T. Ativitavas, P. Chansriwong, C. Nitiwarangkul, R. Ruangkanchanasetr, A. Kositwattanarerk, E. Sirachainan…
    Citation: BMC Cancer 2024 24:200
    Content type: Research Published on:

  45. Epidemiological research on small cell lung cancer (SCLC) is limited and based on cancer registry data. We evaluated the feasibility and validity of using primary care electronic health records (The Health Imp...

    Authors: Lucía Cea Soriano, Jihong Zong and Luis A. García Rodríguez
    Citation: BMC Cancer 2019 19:91
    Content type: Research article Published on:

  46. To compare adenocarcinoma (AC) and adenosquamous carcinoma (ASC) prognoses in patients with FIGO stage IB–IIA cervical cancer who underwent radical hysterectomy.

    Authors: Xiaojing Zhang, Zunfu Lv, Xiaoxian Xu, Zhuomin Yin and Hanmei Lou
    Citation: BMC Cancer 2020 20:664
    Content type: Research article Published on:

  48. Mucin 1 (MUC1) contributes to the growth and metastasis of various cancers, including lung cancer, and MUC1 gene length polymorphisms are associated with susceptibility to lung cancer and its prognosis. In contra...

    Authors: Yasushi Horimasu, Nobuhisa Ishikawa, Sonosuke Tanaka, Chihiro Hirano, Hiroshi Iwamoto, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori and Nobuoki Kohno
    Citation: BMC Cancer 2017 17:263
    Content type: Research article Published on:

  49. The prognostic nutritional index (PNI), an immunity and nutrition based prognostic score, was correlated with clinical outcomes in different tumors. However, the prognostic significance of PNI has not been inv...

    Authors: Bin Li, Zheng Lu, Shengzheng Wang, Junqing Hou, Gang Xia, Heng Li, Bo Yin and Wei Lu
    Citation: BMC Cancer 2020 20:361
    Content type: Research article Published on:

  50. Stereotactic ablative radiotherapy (SABR) has become an established treatment option for medically-inoperable early-stage (Stage I-IIA) non-small cell lung cancer (ES-NSCLC). SABR is able to obtain high rates ...

    Authors: David A. Palma, Hanbo Chen, Houda Bahig, Stewart Gaede, Stephen Harrow, Joanna M. Laba, X. Melody Qu, George B. Rodrigues, Brian P. Yaremko, Edward Yu, Alexander V. Louie, Inderdeep Dhaliwal and Christopher J. Ryerson
    Citation: BMC Cancer 2019 19:1206
    Content type: Study protocol Published on:

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