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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. To compare the value of fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT) and magnetic resonance imaging (MRI) in differentiating benign and malignant ovarian or adnexal tumors.

    Authors: Xianwen Hu, Dandan Li, Zhigang Liang, Yan Liao, Ling Yang, Rui Wang, Pan Wang and Jiong Cai
    Citation: BMC Cancer 2021 21:1080
    Content type: Research Published on:

  3. The management of ovarian cancer remains a challenge. Because of the lack of early symptoms, it is often diagnosed at a late stage when it is likely to have metastasized beyond ovaries. Currently, platinum bas...

    Authors: Zaynab Al-Eisawi, Philip Beale, Charles Chan, Jun Qing Yu, Nicholas Proschogo, Mark Molloy and Fazlul Huq
    Citation: BMC Cancer 2016 16:688
    Content type: Research article Published on:

  4. The purpose of this study was to evaluate invasive and metastatic potential of urothelial cancer by investigating differential expression of various clock genes/proteins participating in the 24 h circadian rhy...

    Authors: Jorunn Litlekalsoy, Kari Rostad, Karl-Henning Kalland, Jens G. Hostmark and Ole Didrik Laerum
    Citation: BMC Cancer 2016 16:549
    Content type: Research article Published on:

  7. Patients with locally advanced bladder cancer (cT3/4 cN0/N+ cM0) have a poor prognosis despite radical surgical therapy and perioperative chemotherapy. Preliminary data suggest that the combination of radiatio...

    Authors: Sebastian C. Schmid, Florestan J. Koll, Claus Rödel, Philipp Maisch, Andreas Sauter, Franziska Beckert, Anna Seitz, Hubert Kübler, Michael Flentje, Felix Chun, Stephanie E. Combs, Kilian Schiller, Jürgen E. Gschwend and Margitta Retz
    Citation: BMC Cancer 2020 20:8
    Content type: Study protocol Published on:

  8. IL-1beta has been implicated in inflammatory episode. In view of the inflammatory nature of cancer cachexia, we determined the predictive value of IL-1B-31 T/C, -511 C/T, +3954 C/T and IL-1RN VNTR gene polymor...

    Authors: Dianliang Zhang, Hongmei Zheng, Yanbing Zhou, Xingming Tang, Baojun Yu and Jieshou Li
    Citation: BMC Cancer 2007 7:45
    Content type: Research article Published on:

  9. Bronchial carcinoids are neuroendocrine tumors that present as typical (TC) and atypical (AC) variants, the latter being more aggressive, invasive and metastatic. Studies of tumor initiating cell (TIC) biology...

    Authors: Reza Bayat Mokhtari, Narges Baluch, Evgeniya Morgatskaya, Sushil Kumar, Angelo Sparaneo, Lucia Anna Muscarella, Sheyun Zhao, Hai-Ling Cheng, Bikul Das and Herman Yeger
    Citation: BMC Cancer 2019 19:864
    Content type: Research article Published on:

  10. Despite its relatively low incidence, pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer deaths because of the aggressive growth/metastasis of the tumor, the lack of early symptoms, and the p...

    Authors: Jesse Bakke, William C. Wright, Anthony E. Zamora, Peter Oladimeji, Jeremy Chase Crawford, Christopher T. Brewer, Robert J. Autry, William E. Evans, Paul G. Thomas and Taosheng Chen
    Citation: BMC Cancer 2019 19:253
    Content type: Research article Published on:

  11. Although sorafenib is the global standard first-line systemic treatment for unresectable hepatocellular carcinoma (HCC), it does not have reliable predictive or prognostic biomarkers. Circulating cell-free DNA...

    Authors: Chung Ryul Oh, Sun-Young Kong, Hyeon-Su Im, Hwa Jung Kim, Min Kyeong Kim, Kyong-Ah Yoon, Eun-Hae Cho, Ja-Hyun Jang, Junnam Lee, Jihoon Kang, Sook Ryun Park and Baek-Yeol Ryoo
    Citation: BMC Cancer 2019 19:292
    Content type: Research article Published on:

  12. Tumor suppression of Transforming Growth Factor (TGF-β) signaling pathway requires an adaptor protein, Embryonic Liver Fodrin (ELF). Disruption of ELF expression resulted in miscolocalization of Smad3 and Smad...

    Authors: Fei Ji, Shun-Jun Fu, Shun-Li Shen, Long-Juan Zhang, Qing-Hua Cao, Shao-Qiang Li, Bao-Gang Peng, Li-Jian Liang and Yun-Peng Hua
    Citation: BMC Cancer 2015 15:116
    Content type: Research article Published on:

  13. The Odontogenic Ameloblast-associated Protein (ODAM) is expressed in a wide range of normal epithelial, and neoplastic tissues, and we have posited that ODAM serves as a novel prognostic biomarker for breast c...

    Authors: James S Foster, Lindsay M Fish, Jonathan E Phipps, Charles T Bruker, James M Lewis, John L Bell, Alan Solomon and Daniel P Kestler
    Citation: BMC Cancer 2013 13:227
    Content type: Research article Published on:

  14. Ovarian cancer is a metastatic disease and one of the leading causes of gynaecology malignancy-related deaths in women. Cancer stem cells (CSCs) are key contributors of cancer metastasis and relapse. Integrins...

    Authors: Chantel Samardzija, Rodney B. Luwor, Michael A. Quinn, George Kannourakis, Jock K. Findlay and Nuzhat Ahmed
    Citation: BMC Cancer 2016 16:432
    Content type: Research article Published on:

  15. Pancreatic ductal adenocarcinoma (PDAC) ranks among the deadliest types of cancer, and it will be meaningful to search for new biomarkers with prognostic value to help clinicians tailor therapeutic strategies.

    Authors: Xiwen Chen, Linying Chen, Jikui Miao, Xingxin Huang, Xiahui Han, Liqin Zheng, Shuoyu Xu, Jianxin Chen and Lianhuang Li
    Citation: BMC Cancer 2024 24:652
    Content type: Research Published on:

  16. The aim of this study was to investigate the prognostic significance and various classifications for anatomic masticator space involvement (MSI) in patients with nasopharyngeal carcinoma (NPC).

    Authors: Dong-Hua Luo, Jing Yang, Hui-Zhi Qiu, Ting Shen, Qiu-Yan Chen, Pei-Yu Huang, Rui Sun, Chao-Nan Qian, Hai-Qiang Mai, Xiang Guo and Hao-Yuan Mo
    Citation: BMC Cancer 2014 14:653
    Content type: Research article Published on:

  17. In premenopausal women, endocrine adjuvant therapy for breast cancer primarily consists of tamoxifen alone or with ovarian suppressive strategies. Toremifene is a chlorinated derivative of tamoxifen, but with ...

    Authors: Ran Gu, Weijuan Jia, Yunjie Zeng, Nanyan Rao, Yue Hu, Shunrong Li, Jiannan Wu, Liang Jin, Lijuan Chen, Meijun Long, Kai Chen, Lili Chen, Qiaozhen Xiao, Mei Wu, Erwei Song and Fengxi Su
    Citation: BMC Cancer 2012 12:161
    Content type: Research article Published on:

  18. To evaluate the clinical outcome in patients with de novo metastatic nasopharyngeal carcinoma (NPC) treated or not treated with locoregional radiotherapy (LRRT) based on plasma Epstein–Barr virus (EBV) DNA lev...

    Authors: Xue-Song Sun, Li-Ting Liu, Sai-Lan Liu, Shan-Shan Guo, Yue-Feng Wen, Hao-Jun Xie, Qing-Nan Tang, Yu-Jing Liang, Xiao-Yun Li, Jin-Jie Yan, Jun Ma, Qiu-Yan Chen, Lin-Quan Tang and Hai-Qiang Mai
    Citation: BMC Cancer 2019 19:92
    Content type: Research article Published on:

  19. Standard treatments for small cell carcinoma of the cervix (SCCC) have not been established. In this study, we aimed to estimate the optimal treatment strategy for SCCC.

    Authors: Mariko Kawamura, Yutaro Koide, Taro Murai, Shunichi Ishihara, Yuuki Takase, Takayuki Murao, Dai Okazaki, Takahiro Yamaguchi, Kaoru Uchiyama, Yoshiyuki Itoh, Takeshi Kodaira, Yuta Shibamoto, Mika Mizuno, Fumitaka Kikkawa and Shinji Naganawa
    Citation: BMC Cancer 2021 21:1046
    Content type: Research article Published on:

  20. Palliative gastrectomy for patients with advanced gastric cancer remains controversial. The objective of the present meta-analysis was to analyze survival outcomes and establish a consensus on whether palliati...

    Authors: Jingxu Sun, Yongxi Song, Zhenning Wang, Xiaowan Chen, Peng Gao, Yingying Xu, Baosen Zhou and Huimian Xu
    Citation: BMC Cancer 2013 13:577
    Content type: Research article Published on:

  21. Hepatocellular carcinoma (HCC) has a high mortality rate, and the mechanisms underlying tumor development and progression remain unclear. However, inactivated tumor suppressor genes might play key roles. DNA m...

    Authors: Yuanxiao Du, Yuqiu Xu, Xuefeng Guo, Chao Tan, Xiaonian Zhu, Guoyu Liu, Xiao Lyu and Chunhua Bei
    Citation: BMC Cancer 2024 24:624
    Content type: Research Published on:

  23. Papillary thyroid microcarcinoma (PTMC) is defined as a papillary thyroid carcinoma less than or equal to 1.0 cm in size. Independent prognostic factors for clinical recurrence of PTMC have not been clearly de...

    Authors: Tae Yong Kim, Suck Joon Hong, Jung Min Kim, Won Gu Kim, Gyungyub Gong, Jin Sook Ryu, Won Bae Kim, Sung-Cheol Yun and Young Kee Shong
    Citation: BMC Cancer 2008 8:296
    Content type: Research article Published on:

  24. The risk of positive lymph nodes in patients with muscle-invasive bladder urothelial carcinoma (MIBC) can be used to guide treatment recommendations. However, little is known about the effect of age on lymph n...

    Authors: Zijian Tian, Lingfeng Meng, Xin Wang, Tongxiang Diao, Maolin Hu, Miao Wang, Ming Liu and Jianye Wang
    Citation: BMC Cancer 2020 20:851
    Content type: Research article Published on:

  25. The aim of this study was to determine whether checkpoint kinase 1 inihibitor (CHK1), LY2603618, and gemcitabine prolong overall survival (OS) compared to gemcitabine alone in patients with unresectable pancre...

    Authors: Berta Laquente, Jose Lopez-Martin, Donald Richards, Gerald Illerhaus, David Z. Chang, George Kim, Philip Stella, Dirk Richel, Cezary Szcylik, Stefano Cascinu, G. L. Frassineti, Tudor Ciuleanu, Karla Hurt, Scott Hynes, Ji Lin, Aimee Bence Lin…
    Citation: BMC Cancer 2017 17:137
    Content type: Research article Published on:

  26. Similarly to other tumor types, an imbalance between unrestrained cell proliferation and impaired apoptosis appears to be a major unfavorable feature of hepatocellular carcinoma (HCC). The members of IAP famil...

    Authors: Claudia Augello, Luca Caruso, Marco Maggioni, Matteo Donadon, Marco Montorsi, Roberto Santambrogio, Guido Torzilli, Valentina Vaira, Caterina Pellegrini, Massimo Roncalli, Guido Coggi and Silvano Bosari
    Citation: BMC Cancer 2009 9:125
    Content type: Research article Published on:

  27. Genomic sequencing in cancer (both tumour and germline), and development of therapies targeted to tumour genetic status, hold great promise for improvement of patient outcomes. However, the imminent introducti...

    Authors: Megan Best, Ainsley J. Newson, Bettina Meiser, Ilona Juraskova, David Goldstein, Kathy Tucker, Mandy L. Ballinger, Dominique Hess, Timothy E. Schlub, Barbara Biesecker, Richard Vines, Kate Vines, David Thomas, Mary-Anne Young, Jacqueline Savard, Chris Jacobs…
    Citation: BMC Cancer 2018 18:389
    Content type: Study protocol Published on:

  28. There is no established second-line treatment after failure of gemcitabine plus nab-paclitaxel (GnP) therapy for metastatic pancreatic cancer (MPC). The purpose of this study was to evaluate the efficacy and t...

    Authors: Masashi Sawada, Akiyoshi Kasuga, Takafumi Mie, Takaaki Furukawa, Takanobu Taniguchi, Koshiro Fukuda, Yuto Yamada, Tsuyoshi Takeda, Ryo Kanata, Masato Matsuyama, Takashi Sasaki, Masato Ozaka and Naoki Sasahira
    Citation: BMC Cancer 2020 20:449
    Content type: Research article Published on:

  29. Neo-adjuvant chemotherapy followed by radical cystectomy with extended pelvic lymph node dissection is considered to be the treatment of choice for patients with muscle invasive bladder cancer (MIBC). Despite ...

    Authors: Valérie Fonteyne, Piet Dirix, Sara Junius, Elke Rammant, Piet Ost, Gert De Meerleer, Martijn Swimberghe and Karel Decaestecker
    Citation: BMC Cancer 2017 17:308
    Content type: Study protocol Published on:

  30. PRECONNECT was an international, phase IIIb trial evaluating the safety and efficacy of trifluridine/tipiracil (FTD/TPI) for metastatic colorectal cancer (mCRC).

    Authors: Julien Taieb, Timothy Price, Loïck Vidot, Bénédicte Chevallier, Lucjan Wyrwicz and Jean-Baptiste Bachet
    Citation: BMC Cancer 2023 23:94
    Content type: Research Published on:

  31. Esophageal adenocarcinoma (EAC) incidence is increasing rapidly. Esophageal cancer has the second lowest 5-year survival rate of people diagnosed with cancer in Canada. Given the poor survival and the potentia...

    Authors: Hla-Hla Thein, Nathaniel Jembere, Kednapa Thavorn, Kelvin K. W. Chan, Peter C. Coyte, Claire de Oliveira, Chin Hur and Craig C. Earle
    Citation: BMC Cancer 2018 18:694
    Content type: Research article Published on:

  32. Pre-clinical studies have shown that furosemide slows cancer cell growth by acting on the Na-K-2Cl transporter, particularly for gastric cancer cells. However, epidemiological studies have not investigated fur...

    Authors: Peipei Liu, Úna C. McMenamin, Andrew D. Spence, Brian T. Johnston, Helen G. Coleman and Chris R. Cardwell
    Citation: BMC Cancer 2019 19:1017
    Content type: Research article Published on:

  33. To predict pathological complete response (pCR) in patients receiving neoadjuvant immunochemotherapy (nICT) for esophageal squamous cell carcinoma (ESCC), we explored the factors that influence pCR after nICT ...

    Authors: Yu Yang, Yan Yi, Zhongtang Wang, Shanshan Li, Bin Zhang, Zheng Sang, Lili Zhang, Qiang Cao and Baosheng Li
    Citation: BMC Cancer 2024 24:460
    Content type: Research Published on:

  34. Metastatic disease in tumors originating from the gastrointestinal tract can exhibit varying degrees of tumor burden at presentation. Some patients follow a less aggressive disease course, characterized by a l...

    Authors: Alessandro Ottaiano, Antonella De Luca, Mariachiara Santorsola, Giosuè Scognamiglio, Annabella Di Mauro, Paolo Chiodini, Matilde Lambiase, Alessandra Sacco, Antonella Petrillo, Vincenza Granata, Roberta Fusco, Edoardo Mercadante, Nicola Martucci, Giuseppe De Luca, Antonello La Rocca, Egidio Celentano…
    Citation: BMC Cancer 2023 23:1010
    Content type: Study Protocol Published on:

  35. In patients with advanced hepatocellular carcinoma (HCC), combination chemotherapy using 5- fluorouracil, cisplatin, and mitoxantrone (FMP) could achieve a response rate > 20%, but the beneficial effect was co...

    Authors: Chau-Ting Yeh, Hui-Chin Chen, Chang-Mu Sung, Cheng-Lung Hsu, Chen-Chun Lin, Kuang-Tse Pan, Jeng-Hwei Tseng and Chien-Fu Hung
    Citation: BMC Cancer 2011 11:117
    Content type: Research article Published on:

  36. Colorectal cancer (CRC) is one of the most common and comprehensively studied malignancies. Hypoxic conditions during formation of CRC may support the development of more aggressive cancers. Hypoxia inducible ...

    Authors: Agnieszka A Rawluszko, Katarzyna E Bujnicka, Karolina Horbacka, Piotr Krokowicz and Paweł P Jagodziński
    Citation: BMC Cancer 2013 13:526
    Content type: Research article Published on:

  37. Tumor necrosis factor-alpha (TNF-α), a key player in cancer-related inflammation, was recently demonstrated to be involved in the lymphatic metastasis of gallbladder cancer (GBC). Vascular endothelial growth f...

    Authors: HaiJie Hong, Lei Jiang, YanFei Lin, CaiLong He, GuangWei Zhu, Qiang Du, XiaoQian Wang, FeiFei She and YanLing Chen
    Citation: BMC Cancer 2016 16:240
    Content type: Research article Published on:

  38. An important component of the RAS signalling pathway, the RAS p21 oncogene, is frequently hyperactivated in breast cancer. Its expression in tumor tissue has been linked to poor clinical outcome. This study wa...

    Authors: Malgorzata Banys-Paluchowski, Tanja Fehm, Wolfgang Janni, Bahriye Aktas, Peter A. Fasching, Sabine Kasimir-Bauer, Karin Milde-Langosch, Klaus Pantel, Brigitte Rack, Sabine Riethdorf, Erich-Franz Solomayer, Isabell Witzel and Volkmar Müller
    Citation: BMC Cancer 2018 18:541
    Content type: Research article Published on:

  39. First full term pregnancy (FFTP) completed at a young age has been linked to low long term breast cancer risk, whereas late FFTP pregnancy age confers high long term risk, compared to nulliparity. Our hypothes...

    Authors: Wenyi Qin, Ke Zhang, Beth Kliethermes, Rachel L Ruhlen, Eva P Browne, Kathleen F Arcaro and Edward R Sauter
    Citation: BMC Cancer 2012 12:100
    Content type: Research article Published on:

  40. There is currently limited information regarding the prognostic ability of the dNLR-PNI (the combination of the derived neutrophil-to-lymphocyte ratio [dNLR] and prognostic nutritional index [PNI]) for hepatoc...

    Authors: Chang Liu, Lei Li, Wu-sheng Lu, Hua Du, Lu-nan Yan, Tian-fu Wen, Wu-ran Wei, Li Jiang and Ming-qing Xu
    Citation: BMC Cancer 2018 18:216
    Content type: Research article Published on:

  41. Small extracellular vesicles (sEVs) have great potential as new biomarkers in liquid biopsy. However, due to the limitations of sEVs extraction and component analysis procedures, further clinical applications ...

    Authors: Yifan Sun, Miao Li, Xiaoshan Zhang, Dongjie Xu, Jie Wu, Xinrui Gu, Adeel Khan, Han Shen and Zhiyang Li
    Citation: BMC Cancer 2023 23:614
    Content type: Research Published on:

  42. Prostate cancer (PCa) is becoming the most common malignancy in men worldwide. We investigated the effect of astragaloside IV combined with PESV on the gut microbiota and metabolite of PCa mice and the process...

    Authors: Xujun You, Junfeng Qiu, Qixin Li, Qing Zhang, Wen Sheng, Yiguo Cao and Wei Fu
    Citation: BMC Cancer 2024 24:472
    Content type: Research Published on:

  43. The Aurora kinase family members, Aurora-A, -B and -C, are involved in the regulation of mitosis, and alterations in their expression are associated with cell malignant transformation. To date no information o...

    Authors: Enke Baldini, Yannick Arlot-Bonnemains, Salvatore Sorrenti, Caterina Mian, Maria R Pelizzo, Enrico De Antoni, Silvio Palermo, Stefania Morrone, Susi Barollo, Angela Nesca, Costanzo G Moretti, Massimino D'Armiento and Salvatore Ulisse
    Citation: BMC Cancer 2011 11:411
    Content type: Research article Published on:

  44. Mutational analysis of the KRAS gene has recently been established as a complementary in vitro diagnostic tool for the identification of patients with colorectal cancer who will not benefit from anti-epidermal gr...

    Authors: Alfonso Sánchez-Muñoz, Elena Gallego, Vanessa de Luque, Luís G Pérez-Rivas, Luís Vicioso, Nuria Ribelles, José Lozano and Emilio Alba
    Citation: BMC Cancer 2010 10:136
    Content type: Research article Published on:

  45. Loss of heterozygosity (LOH) at chromosome arm 16q is frequently observed in human breast cancer, suggesting that one or more target tumor suppressor genes (TSGs) are located there. However, detailed mapping o...

    Authors: Anne-Marie Cleton-Jansen, Ronald van Eijk, Marcel Lombaerts, Marjanka K Schmidt, Laura J Van't Veer, Katja Philippo, Rhyenne ME Zimmerman, Johannes L Peterse, Vincent TBHM Smit, Tom van Wezel and Cees J Cornelisse
    Citation: BMC Cancer 2008 8:105
    Content type: Research article Published on:

  47. Brain metastasis represents a major complication with a significantly shorter overall survival of many oncological diseases, in particular of lung cancer, breast cancer and malignant melanoma patients. However...

    Authors: Annalen Bleckmann, Benjamin Kirchner, Manuel Nietert, Micha Peeck, Marko Balkenhol, Daniela Egert, T. Veit Rohde, Tim Beißbarth and Tobias Pukrop
    Citation: BMC Cancer 2020 20:973
    Content type: Research article Published on:

  48. Stomach cancer (SC) is a type of cancer, which is derived from the stomach mucous membrane. As there are non-specific symptoms or no noticeable symptoms observed at the early stage, newly diagnosed SC cases us...

    Authors: Erli Gu, Wei Song, Ajing Liu and Hong Wang
    Citation: BMC Cancer 2020 20:490
    Content type: Database Published on:

  49. Borderline resectable pancreatic cancer (BRPC) is a category of pancreatic cancer that is anatomically widely spread, and curative resection is uncommon with upfront surgery. Intensity-modulated radiation ther...

    Authors: Toshihiko Masui, Kazuyuki Nagai, Takayuki Anazawa, Asahi Sato, Yuichiro Uchida, Kenzo Nakano, Akitada Yogo, Akihiro Kaneda, Naoto Nakamura, Michio Yoshimura, Takashi Mizowaki, Norimitsu Uza, Akihisa Fukuda, Shigemi Matsumoto, Masashi Kanai, Hiroyoshi Isoda…
    Citation: BMC Cancer 2022 22:119
    Content type: Research Published on:

  50. There is evidence that derangement in serum electrolytes like sodium and potassium is associated with increased morbidity and mortality among hospitalized critically ill patients, but their role in the context...

    Authors: Arunangshu Ghoshal, Hans Garmo, Niklas Hammar, Ingmar Jungner, Håkan Malmström, Göran Walldius and Mieke Van Hemelrijck
    Citation: BMC Cancer 2018 18:1169
    Content type: Research article Published on:

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