Skip to main content

Articles

Page 51 of 335

  1. While many studies investigated changes in working status in cancer survivors, most studies have been performed in survivors of breast cancer and few studies evaluated factors associated with changes in the wo...

    Authors: Danbee Kang, Ka Ryeong Bae, Ho Young Kim, Yeojin Ahn, Nayeon Kim, Youngmog Shim, Tae Sung Sohn, Woo Yong Lee, Ji Hyun Baek, Sun-Seog Kweon and Juhee Cho
    Citation: BMC Cancer 2022 22:917
    Content type: Research Published on:

  2. Extralevator abdominoperineal excision (ELAPE) has been recommended for treating low rectal cancer due to its potential advantages in improving surgical safety and oncologic outcomes as compared to conventiona...

    Authors: Shaowei Sun, Shengbo Sun, Xiangyun Zheng, Jiangtao Yu, Wenchang Wang, Qing Gong, Guowei Zhao, Jing Li and Huanhu Zhang
    Citation: BMC Cancer 2022 22:916
    Content type: Research Published on:

  3. The non-inferiority of dexamethasone (DEX) on day 1, with or without low-dose DEX on days 2 and 3, combined with oral NEPA (netupitant/palonosetron), compared with the guideline-consistent use of DEX was demon...

    Authors: Luigi Celio, Diego Cortinovis, Alessio Aligi Cogoni, Luigi Cavanna, Olga Martelli, Simona Carnio, Elena Collovà, Federica Bertolini, Fausto Petrelli, Alessandra Cassano, Rita Chiari, Francesca Zanelli, Salvatore Pisconti, Isabella Vittimberga, Antonietta Letizia, Andrea Misino…
    Citation: BMC Cancer 2022 22:915
    Content type: Research Published on:

  4. The aim of this study was to establish and validate a clinical prediction model for assessing the risk of metastasis and patient survival in Ewing's sarcoma (ES).

    Authors: Wenle Li, Shengtao Dong, Yuewei Lin, Huitao Wu, Mengfei Chen, Chuan Qin, Kelin Li, JunYan Zhang, Zhi-Ri Tang, Haosheng Wang, Kang Huo, Xiangtao Xie, Zhaohui Hu, Sirui Kuang and Chengliang Yin
    Citation: BMC Cancer 2022 22:914
    Content type: Research Published on:

  5. The modulation of perioperative inflammation seems crucial to improve postoperative morbidity and cancer-related outcomes in patients undergoing oncological surgery. Data from the literature suggest that perio...

    Authors: Joséphine Magnin, Isabelle Fournel, Alexandre Doussot, Jean-Marc Régimbeau, Philippe Zerbib, Guillaume Piessen, Laura Beyer-Berjot, Sophie Deguelte, Zaher Lakkis, Lilian Schwarz, David Orry, Ahmet Ayav, Fabrice Muscari, François Mauvais, Guillaume Passot, Nelson Trelles…
    Citation: BMC Cancer 2022 22:913
    Content type: Study protocol Published on:

  6. Lenvatinib is appropriate for reducing the production of nitric oxide (NO) and facilitating as block angiogenesis. However, to our knowledge, there are no data that support the correlation between NO and clini...

    Authors: Atsushi Kawamura, Haruki Uojima, Makoto Chuma, Xue Shao, Hisashi Hidaka, Takahide Nakazawa, Akira Take, Yoshihiko Sakaguchi, Kazushi Numata, Makoto Kako, Akito Nozaki, Shintaro Azuma, Kazue Horio, Chika Kusano and Koichiro Atsuda
    Citation: BMC Cancer 2022 22:912
    Content type: Research Published on:

  7. The histopathological growth patterns (HGPs) are a prognostic and predictive biomarker in colorectal cancer liver metastasis (CRLM). This study evaluates the relationship between the HGP and primary colorectal...

    Authors: Diederik J. Höppener, Jean-Luc P. L. Stook, Boris Galjart, Pieter M. H. Nierop, Iris D. Nagtegaal, Peter B. Vermeulen, Dirk J. Grünhagen, Cornelis Verhoef and Michail Doukas
    Citation: BMC Cancer 2022 22:911
    Content type: Research Published on:

  8. Controversy exists regarding the relationship of the outcome of patients with colorectal cancer (CRC) with the time from symptom onset to diagnosis. The aim of this study is to investigate this association, wi...

    Authors: Magdalena Esteva, Alfonso Leiva, María Ramos-Monserrat, Alejandro Espí, Luis González-Luján, Francesc Macià, Cristiane Murta-Nascimento, María A. Sánchez-Calavera, Rosa Magallón, Vanesa Balboa-Barreiro, Teresa Seoane-Pillado and Sonia Pertega-Díaz
    Citation: BMC Cancer 2022 22:910
    Content type: Research Published on:

  9. HuR/ELAVL1 (embryonic lethal abnormal vision 1) was a downstream target of miR-29b in some cancer cells. HuR protein exerts important prognostic effects of involving in the pathogenesis and development of acut...

    Authors: Yong-Jing Tang, Wei Wu, Qiao-Qian Chen, Shu-Han Liu, Zhi-Yuan Zheng, Zhao-Lei Cui, Jian-Ping Xu, Yan Xue and Dong-Hong Lin
    Citation: BMC Cancer 2022 22:909
    Content type: Research Published on:

  10. Less than 20 % of patients with resectable oesophageal adenocarcinoma obtain a pathological response following neoadjuvant chemotherapy. Studies using oesophageal cancer cell lines have shown that drug sensiti...

    Authors: Shereen El Mashed, Tracey R. O’Donovan, Elaine Kay, Anthony O’Grady, Damian McManus, Richard C. Turkington and Sharon L. McKenna
    Citation: BMC Cancer 2022 22:908
    Content type: Research Published on:

  11. Only a limited proportion of patients with metastatic colorectal cancer (mCRC) receives metastatic surgery (including local ablative therapy). The aim was to investigate whether hospital volume and hospital le...

    Authors: Malin Ljunggren, Caroline E. Weibull, Emma Rosander, Gabriella Palmer, Bengt Glimelius, Anna Martling and Caroline Nordenvall
    Citation: BMC Cancer 2022 22:907
    Content type: Research Published on:

  12. Older patients with cancer have poorer prognosis compared to younger patients. Moreover, prognosis is related to how cancer is identified, and where in the healthcare system patients present, i.e. routes to di...

    Authors: B. Danckert, N. L. Christensen, A. Z. Falborg, H. Frederiksen, G. Lyratzopoulos, S. McPhail, A. F. Pedersen, J. Ryg, L. A. Thomsen, P. Vedsted and H. Jensen
    Citation: BMC Cancer 2022 22:906
    Content type: Research Published on:

  13. Previous study has shown that chemokine-like factor (CKLF)-like MARVEL transmembrane domain-containing family member 4 (CMTM4) can bind and maintain programmed cell death ligand 1 (PD-L1) expression to promote...

    Authors: Shengkui Tan, Xuefeng Guo, Chunhua Bei, Huixia Zhang, Di Li, Xiaonian Zhu and Hongzhuan Tan
    Citation: BMC Cancer 2022 22:905
    Content type: Research article Published on:

  14. Accumulating evidence has revealed that the gut microbiota influences the effectiveness of immune checkpoint inhibitors (ICIs) in cancer patients. As a part of the human microbiome, Helicobacter pylori (H. pylori...

    Authors: Hebin Che, Qi Xiong, Jinxia Ma, Shixue Chen, Huan Wu, Hongli Xu and Baicun Hou
    Citation: BMC Cancer 2022 22:904
    Content type: Research Published on:

  15. The aim of this work was to screen and validate biomarkers of ovarian cancer-initiating cells to detect the mechanisms of recurrence of epithelial ovarian cancer (EOC).

    Authors: Jie Yin, Yiping Wen, Jing Zeng, Yanyan Zhang, Jiayu Chen, Yanmei Zhang, Tiantian Han, Xiaoying Li, Hong Huang, Yan Cai, Ying Jin, Yan Li, Wei Guo and Lingya Pan
    Citation: BMC Cancer 2022 22:903
    Content type: Research Published on:

  16. Increasing number of individuals will have first-degree relatives (FDRs) diagnosed with colorectal cancer (CRC), as a second primary malignancy (CRCa-2) after a non-CRC cancer. We aimed to estimate whether and...

    Authors: Guoqiao Zheng, Jan Sundquist, Kristina Sundquist and Jianguang Ji
    Citation: BMC Cancer 2022 22:902
    Content type: Research Published on:

  17. There is limited real-world evidence that describes patients with newly diagnosed multiple myeloma (NDMM) treated with the bortezomib, lenalidomide, and dexamethasone (VRd) triplet regimen. We evaluated patien...

    Authors: Rohan Medhekar, Tao Ran, Alex Z. Fu, Sharmila Patel and Shuchita Kaila
    Citation: BMC Cancer 2022 22:901
    Content type: Research Published on:

  18. Hexokinase 2 (HK2) is an enzyme that catalyses the conversion of glucose to glucose-6-phosphate, which has been found to be associated with malignant tumour growth. However, the potential immunological and cli...

    Authors: Yishan Huang, Fan Ouyang, Fengxia Yang, Ning Zhang, Weijiang Zhao, Hongwu Xu and Xiaojun Yang
    Citation: BMC Cancer 2022 22:900
    Content type: Research Published on:

  19. New-generation silicon-photomultiplier (SiPM)-based PET/CT systems exhibit an improved lesion detectability and image quality due to a higher detector sensitivity. Consequently, the acquisition time can be red...

    Authors: Pedro Fragoso Costa, Walter Jentzen, Alissa Brahmer, Ilektra-Antonia Mavroeidi, Fadi Zarrad, Lale Umutlu, Wolfgang P. Fendler, Christoph Rischpler, Ken Herrmann, Maurizio Conti, Robert Seifert, Miriam Sraieb, Manuel Weber and David Kersting
    Citation: BMC Cancer 2022 22:899
    Content type: Research Published on:

  20. Allogeneic stem cell transplantation (allo-SCT) is a potentially lifesaving treatment for high-risk hematological malignancy, but survivors experience markedly elevated rates of cardiovascular disease and asso...

    Authors: Hayley T. Dillon, Nicholas J. Saner, Tegan Ilsley, David Kliman, Andrew Spencer, Sharon Avery, David W. Dunstan, Robin M. Daly, Steve F. Fraser, Neville Owen, Brigid M. Lynch, Bronwyn A. Kingwell, Andre La Gerche and Erin J. Howden
    Citation: BMC Cancer 2022 22:898
    Content type: Study protocol Published on:

  21. Quality of life (QoL) has become an important measure for evaluating cancer patients’ treatment and prognosis. Breast cancer patients are at an increased risk of experiencing poor QoL during active treatment o...

    Authors: Mikiyas Amare Getu, Changying Chen, Panpan Wang, Eva Johanna Kantelhardt and Adamu Addissie
    Citation: BMC Cancer 2022 22:897
    Content type: Research Published on:

  22. The presence of mixed-lineage leukaemia rearrangement (MLL-r) in paediatric patients with acute myeloid leukaemia (AML) is a poor prognostic predictor. Whether allogeneic haematopoietic stem cell transplantati...

    Authors: Lu Bai, Yong-zhan Zhang, Chen-hua Yan, Yu Wang, Lan-ping Xu, Xiao-hui Zhang, Le-ping Zhang, Xiao-jun Huang and Yi-fei Cheng
    Citation: BMC Cancer 2022 22:896
    Content type: Research Published on:

  23. To evaluate the diagnostic performance of combined multiparametric 18F-fluorodeoxyglucose positron emission tomography (18FDG PET) with clinical characteristics in differentiating thymic epithelial tumors (TETs) ...

    Authors: Guanyun Wang, Lei Du, Xia Lu, Jiajin Liu, Mingyu Zhang, Yue Pan, Xiaolin Meng, Xiaodan Xu, Zhiwei Guan and Jigang Yang
    Citation: BMC Cancer 2022 22:895
    Content type: Research Published on:

  24. Pancreatic cancer (PC) is a highly malignant tumor featured with high intra-tumoral heterogeneity and poor prognosis. Cell-in-cell (CIC) structures have been reported in multiple cancers, and their presence is...

    Authors: Jianlu Song, Rexiati Ruze, Yuan Chen, Ruiyuan Xu, Xinpeng Yin, Chengcheng Wang, Qiang Xu and Yupei Zhao
    Citation: BMC Cancer 2022 22:894
    Content type: Research Published on:

  25. Globally breast cancer is the leading cause of cancer with an estimated 2.3 million new cases and 685,000 deaths in 2020. Late presentation is the hallmark of breast cancer in Ghana for which ignorance and fea...

    Authors: Josephine Nsaful, Florence Dedey, Edmund Nartey, Juliana Labi, Nii Armah Adu-Aryee and Joe Nat Clegg-Lamptey
    Citation: BMC Cancer 2022 22:893
    Content type: Research Published on:

  26. Worldwide 85% of cervical cancer (CC) related deaths occur in low- and middle-income countries. Sub-Saharan Africa is burdend by an overlapping high incidence of CC as well as HIV infection, a risk factor for ...

    Authors: Laura Glasmeyer, Ruby Doryn Mcharo, Liset Torres, Tessa Lennemann, Elizabeth Danstan, Nice Mwinuka, Mona Judick, William Mueller, Wilbert Mbuya, Michael Hölscher, Ralph Lellé, Christof Geldmacher, Arne Kroidl and John Rwegoshora France
    Citation: BMC Cancer 2022 22:892
    Content type: Research Published on:

  27. Alveolar soft part sarcoma (ASPS) is a rare histological subtype of soft-tissue sarcoma, which remains refractory to conventional cytotoxic chemotherapy. We aimed to characterize ASPS and investigate whether t...

    Authors: Tomohiro Fujiwara, Eiji Nakata, Toshiyuki Kunisada, Toshifumi Ozaki and Akira Kawai
    Citation: BMC Cancer 2022 22:891
    Content type: Research Published on:

  28. While individuals with normal gastrointestinal (GI) mucosa on endoscopy have a lower risk of colorectal cancer, risks of other cancers remain unexplored.

    Authors: Jiangwei Sun, Fang Fang, Ola Olén, Mingyang Song, Jonas Halfvarson, Bjorn Roelstraete, Hamed Khalili and Jonas F. Ludvigsson
    Citation: BMC Cancer 2022 22:890
    Content type: Research Published on:

  29. This study aimed to develop and externally validate contrast-enhanced (CE) T1-weighted MRI-based radiomics for the identification of epidermal growth factor receptor (EGFR) mutation, exon-19 deletion and exon-...

    Authors: Ying Fan, Yue Dong, Xinyan Sun, Huan Wang, Peng Zhao, Hongbo Wang and Xiran Jiang
    Citation: BMC Cancer 2022 22:889
    Content type: Research Published on:

  30. Histocompatibility minor 13 (HM13) is a signal sequence stubbed intramembrane cleavage catalytic protein that is essential for cell signaling, intracellular communication, and cancer. However, the expression o...

    Authors: Genhao Zhang, Xianping Lv, Qiankun Yang and Hongchun Liu
    Citation: BMC Cancer 2022 22:888
    Content type: Research Published on:

  31. EBV infection in nasopharyngeal cancer ensued in latent infection mode. In this latent infection various EBV oncoproteins such as EBNA1 and LMP1 was expressed. EBV oncoproteins could theoretically recruit immu...

    Authors: Soehartati A. Gondhowiardjo, Marlinda Adham, Lisnawati Rachmadi, Tubagus Djumhana Atmakusuma, Demak Lumban Tobing, Mahesa Auzan, Agustinus Darmadi Hariyanto, Dede Sulaeman, Tiara Bunga Mayang Permata and Handoko
    Citation: BMC Cancer 2022 22:887
    Content type: Research article Published on:

  33. Pyroptosis is a programmed cell death mediated by the gasdermin superfamily, accompanied by inflammatory and immune responses. Exogenously activated pyroptosis is still not well characterized in the tumor micr...

    Authors: Huihan Yu, Meiting Gong, Jian Qi, Chenggang Zhao, Wanxiang Niu, Suling Sun, Shuyang Li, Bo Hong, Junchao Qian, Hongzhi Wang, Xueran Chen and Zhiyou Fang
    Citation: BMC Cancer 2022 22:885
    Content type: Research Published on:

  34. Hepatocellular carcinoma (HCC) is a fatal disease characterized by early genetic alterations in telomerase reverse transcriptase promoter (TERTp) and β-catenin (CTNNB1) genes and immune cell activation in the ...

    Authors: Filip Ambrozkiewicz, Andriy Trailin, Lenka Červenková, Radka Vaclavikova, Vojtech Hanicinec, Mohammad Al Obeed Allah, Richard Palek, Vladislav Třeška, Ondrej Daum, Zbyněk Tonar, Václav Liška and Kari Hemminki
    Citation: BMC Cancer 2022 22:884
    Content type: Research Published on:

  35. Owing to the low ratio of patients benefitting from immunotherapy, patient stratification becomes necessary. An accurate patient stratification contributes to therapy for different tumor types. Therefore, this...

    Authors: Zirui Zhao, Haohan Liu, Deliang Fang, Xingyu Zhou, Shaoji Zhao, Chaoyue Zhang, Jinning Ye and Jianbo Xu
    Citation: BMC Cancer 2022 22:883
    Content type: Research Published on:

  36. Glioblastoma (GBM) is the most common primary intracranial tumor in the central nervous system, and resistance to temozolomide is an important reason for the failure of GBM treatment. We screened out that Solu...

    Authors: Lan Jiang, Jianke Yang, Qiancheng Xu, Kun Lv and Yunpeng Cao
    Citation: BMC Cancer 2022 22:882
    Content type: Research Published on:

  37. Glutathione Peroxidase 4 (GPX4) is a key protein that inhibits ferroptosis. However, its biological regulation and mechanism in endometrial cancer (EC) have not been reported in detail.

    Authors: Sitian Wei, Zhicheng Yu, Rui Shi, Lanfen An, Qi Zhang, Qian Zhang, Tangansu Zhang, Jun Zhang and Hongbo Wang
    Citation: BMC Cancer 2022 22:881
    Content type: Research Published on:

  38. Distinguishing patients at a greater risk of recurrence is essential for treating locoregional advanced nasopharyngeal carcinoma (NPC). This study aimed to explore the potential of aldo–keto reductase 1C4 (AKR...

    Authors: Shan-Shan Guo, Yan-Zhou Chen, Li-Ting Liu, Rong-Ping Liu, Yu-Jing Liang, Dong-Xiang Wen, Jing Jin, Lin-Quan Tang, Hai-Qiang Mai and Qiu-Yan Chen
    Citation: BMC Cancer 2022 22:880
    Content type: Research Published on:

  39. Pancreatic cancer (PC) is a highly lethal and aggressive disease with its incidence and mortality quite discouraging. A robust prognostic signature and novel biomarkers are urgently needed for accurate stratif...

    Authors: Chengcheng Wang, Yuan Chen, Yin Xinpeng, Ruiyuan Xu, Jianlu Song, Rexiati Ruze, Qiang Xu and Yupei Zhao
    Citation: BMC Cancer 2022 22:879
    Content type: Research Published on:

  40. Pre-treatment risk and prognostic groups are the cornerstone for deciding management in non-metastatic prostate cancer. All however, were developed in the pre-MRI era. Here we compared categorisation of cancer...

    Authors: Artitaya Lophatananon, Matthew H. V. Byrne, Tristan Barrett, Anne Warren, Kenneth Muir, Ibifuro Dokubo, Fanos Georgiades, Mostafa Sheba, Lisa Bibby and Vincent J. Gnanapragasam
    Citation: BMC Cancer 2022 22:878
    Content type: Research Published on:

  41. Breast cancer incidence is increasing rapidly in Latin America, with a higher proportion of cases among young women than in developed countries. Studies have linked inflammation to breast cancer development, b...

    Authors: Emma Fontvieille, Mathilde His, Carine Biessy, Anne-Sophie Navionis, Gabriela Torres-Mejía, Angélica Ángeles-Llerenas, Isabel Alvarado-Cabrero, Gloria Inés Sánchez, Edgar Navarro, Yorlany Rodas Cortes, Carolina Porras, Ana Cecilia Rodriguez, Maria Luisa Garmendia, José Luis Soto, Leonor Moyano, Peggy L. Porter…
    Citation: BMC Cancer 2022 22:877
    Content type: Research Published on:

  42. Evidences have indicated that miR-26a-5p regulates the malignant properties of various tumor cells. However, the influences of miR-26a-5p on proliferation, apoptosis and invasion are still vague in the cervica...

    Authors: Ming Li, Yubo Xiao, Minqi Liu, Qian Ning, Ziye Xiang, Xiang Zheng, Shengsong Tang and Zhongcheng Mo
    Citation: BMC Cancer 2022 22:876
    Content type: Research Published on:

  43. We studied the prognosis and clinicopathological background of lung adenocarcinoma predominance among patients who underwent lobectomy using data from the Japanese Joint Committee of Lung Cancer Registry.

    Authors: Hiroyuki Ito, Hiroshi Date, Yasushi Shintani, Etsuo Miyaoka, Ryoichi Nakanishi, Mitsutaka Kadokura, Shunsuke Endo, Masayuki Chida, Ichiro Yoshino and Hidemi Suzuki
    Citation: BMC Cancer 2022 22:875
    Content type: Research Published on:

  44. Breast cancer, comprising of several sub-phenotypes, is a leading cause of female cancer-related mortality in the UK and accounts for 15% of all cancer cases. Chemoresistant sub phenotypes of breast cancer rem...

    Authors: Layla Alnoumas, Lisa van den Driest, Zoe Apczynski, Alison Lannigan, Caroline H. Johnson, Nicholas J. W. Rattray and Zahra Rattray
    Citation: BMC Cancer 2022 22:874
    Content type: Research Published on:

  45. Lycorine (Lyc) is a natural alkaloid derived from medicinal plants of the Amaryllidaceae family. Lyc has been reported to inhibit the recurrence and metastasis of different kinds of tumors. However, Lyc’s effe...

    Authors: Fei Lv, XiaoQi Li and Ying Wang
    Citation: BMC Cancer 2022 22:873
    Content type: Research Published on:

  46. The determination of HER2 expression status contributes significantly to HER2-targeted therapy in breast carcinoma. However, an economical, efficient, and non-invasive assessment of HER2 is lacking. We aimed t...

    Authors: Aqiao Xu, Xiufeng Chu, Shengjian Zhang, Jing Zheng, Dabao Shi, Shasha Lv, Feng Li and Xiaobo Weng
    Citation: BMC Cancer 2022 22:872
    Content type: Research Published on:

  47. EphrinA (EFNA) are Eph receptor ligands that regulate various disease processes. Nonetheless, the expression characteristics of EFNAs in pan-cancer, their relationship with tumor immune microenvironment, and p...

    Authors: Zonglin Jiao, Xiao Feng, Yuqing Cui, Lei Wang, Junqing Gan, Yanbin Zhao and Qingwei Meng
    Citation: BMC Cancer 2022 22:871
    Content type: Research Published on:

  48. Aberrant fibroblast growth factor receptor (FGFR) signaling can substantially influence oncogenicity. Despite that FGFR gene abnormality is often detected by cancer genome profiling tests, there is no tumor-ag...

    Authors: Yohei Chiba, Kazuki Sudo, Yuki Kojima, Hitomi Okuma, Shinji Kohsaka, Ryunosuke Machida, Masahiko Ichimura, Kenta Anjo, Kazumi Kurishita, Natsuko Okita, Kenichi Nakamura, Ichiro Kinoshita, Masanobu Takahashi, Junichi Matsubara, Hitoshi Kusaba, Kan Yonemori…
    Citation: BMC Cancer 2022 22:869
    Content type: Study protocol Published on:

  49. Preoperative neoadjuvant chemoradiation (nCRT) has been the standard treatment for locally advanced rectal cancer. Serum biomarkers to stratify patients with respect to prognosis and response to nCRT are neede...

    Authors: Hanyang Wang, Dengbo Ji, Huifang Tian, Zhaoya Gao, Can Song, Jinying Jia, Xinxin Cui, Lijun Zhong, Jing Shen and Jin Gu
    Citation: BMC Cancer 2022 22:868
    Content type: Research Published on:

  50. LncRNA N6-methylandenosine (m6A) modification has been shown to be associated with the constitution of the tumor microenvironment (TME) and tumorigenesis. It’s essential to understand the mechanisms of lncRNA ...

    Authors: Bo Chen, Zhan Yang, Zhichao Lang, Qiqi Tao, Rongrong Zhang, Yating Zhan, Xuantong Xu, Kai Zhu, Jianjian Zheng, Zhengping Yu and Suhui Yu
    Citation: BMC Cancer 2022 22:867
    Content type: Research Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us