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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  2. AminoIndexâ„¢ Cancer Screening (AICS (lung)) was developed as a screening test for lung cancer using a multivariate analysis of plasma-free amino acid (PFAA) profiles. According to the developed index composed o...

    Authors: Masahiko Higashiyama, Ryohei Miyazaki, Hiroshi Yamamoto, Takashi Anayama, Shinya Kikuchi, Kentaro Hirohashi, Jiro Okami, Tomohiro Maniwa, Toru Kimura, Kazumasa Orihashi and Fumio Imamura
    Citation: BMC Cancer 2020 20:1100
    Content type: Research article Published on:

  3. Lung adenocarcinoma (LUAD) is an extraordinarily malignant tumor, with rapidly increasing morbidity and poor prognosis. Immunotherapy has emerged as a hopeful therapeutic modality for lung adenocarcinoma. Furt...

    Authors: Qianhe Ren, Qifan Li, Chenye Shao, Pengpeng Zhang, Zhuangzhuang Hu, Jun Li, Wei Wang and Yue Yu
    Citation: BMC Cancer 2023 23:897
    Content type: Research Published on:

  4. Magnetic resonance imaging (MRI) enables a more sensitive detection of brain metastasis and stereotactic irradiation (SRI) efficiently controls brain metastasis. In limited-stage small cell lung cancer (LS-SCL...

    Authors: Yuichi Ozawa, Minako Omae, Masato Fujii, Takashi Matsui, Masato Kato, Shinya Sagisaka, Kazuhiro Asada, Masato Karayama, Toshihiro Shirai, Kazumasa Yasuda, Yutaro Nakamura, Naoki Inui, Kazunari Yamada, Koshi Yokomura and Takafumi Suda
    Citation: BMC Cancer 2015 15:589
    Content type: Research article Published on:

  5. Pygopus 2 (Pygo2) is a Pygo family member and an important component of the Wnt signaling transcriptional complex. Despite this data, no clinical studies investigating Pygo2 expression in lung cancer have yet ...

    Authors: Yang Liu, Qian-Ze Dong, Si Wang, Chang-Qing Fang, Yuan Miao, Liang Wang, Ming-Zhu Li and En-Hua Wang
    Citation: BMC Cancer 2013 13:346
    Content type: Research article Published on:

  6. The efficacy of bevacizumab in non-small cell lung cancer (NSCLC) patients is unsatisfactory, and the selection of suitable patients is still challenging. Given the epigenetic modifications can contribute to a...

    Authors: Butuo Li, Chao Jiang, Yiyue Xu, Xinyu Fan, Linlin Yang, Bing Zou, Bingjie Fan and Linlin Wang
    Citation: BMC Cancer 2022 22:828
    Content type: Research Published on:

  8. In a previously published report we characterized the expression of the metastasis-associated proteins S100A4, osteopontin (OPN) and ephrin-A1 in a prospectively collected panel of non-small cell lung cancer (...

    Authors: Ane Kongsgaard Rud, Kjetil Boye, Miriam Øijordsbakken, Marius Lund-Iversen, Ann Rita Halvorsen, Steinar K Solberg, Gisle Berge, Åslaug Helland, Odd Terje Brustugun and Gunhild M Mælandsmo
    Citation: BMC Cancer 2013 13:540
    Content type: Research article Published on:

  9. N6-methyladenine (m6A) is the most common modification of mRNA and IncRNA in higher organisms. m6A has been confirmed to be related to the formation and progression of tumors and m6A-related genes can be used as ...

    Authors: Jialin Qu, Li Wang, Man Jiang, Zhimin Wei, Guangming Fu and Xiaochun Zhang
    Citation: BMC Cancer 2021 21:1265
    Content type: Research Published on:

  10. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) combined with cytotoxic chemotherapy are highly effective in the treatment of advanced non–small-cell lung cancer (NSCLC) with EGFR mutat...

    Authors: Kai Shang, Hongxiang Huang, Yongkang Xu, Yangyang Liu, Zhihui Lu and Li Chen
    Citation: BMC Cancer 2022 22:1295
    Content type: Research article Published on:

  11. COPD patients are at increased risk of developing non-small cell lung carcinoma that has a worse prognosis. Oxidative stress contributes to carcinogenesis and is increased in COPD patients due to mitochondrial...

    Authors: F. Ng Kee Kwong, A. G. Nicholson, S. Pavlidis, I. M. Adcock and K. F. Chung
    Citation: BMC Cancer 2018 18:1238
    Content type: Research article Published on:

  12. This study aimed to identify potential predictive factors for the survival of advanced non small-cell lung cancer (NSCLC) patients undergoing first-line platinum-based chemotherapy.

    Authors: Jun Ying, Danfei Zhou, Tongjie Gu, Jianda Huang and Haijian Liu
    Citation: BMC Cancer 2019 19:288
    Content type: Research article Published on:

  13. This study aimed to investigate the clinical utility of diverse aneuploid circulating tumor cell (CTC) subtypes and particularly CTC-associated white blood cell (CTC-WBC) clusters in predicting treatment respo...

    Authors: Ying Wang, Yanxia Liu, Zhiyun Zhang, Baohua Lu, Yuan Gao, Li Tong, Mingming Hu, Peter Ping Lin, Baolan Li and Tongmei Zhang
    Citation: BMC Cancer 2023 23:578
    Content type: Research Published on:

  14. Basement membrane (BM) is an important component of the extracellular matrix, which plays an important role in the growth and metastasis of tumor cells. However, few biomarkers based on BM have been developed ...

    Authors: Xuezhou Zhang, Baoan Hong, Hongwei Li, Jiahui Zhao, Mingchuan Li, Dechao Wei, Yongxing Wang and Ning Zhang
    Citation: BMC Cancer 2024 24:746
    Content type: Research Published on:

  15. Although postoperative adjuvant chemoradiotherapies prevent recurrence for some patients with ampullary cancer, the recurrence rate is as high as 29 % in patients with stage I cancer. In an effort to identify ...

    Authors: Cheng-Lin Wu, Ying-Jui Chao, Ta-Ming Yang, Yi-Ling Chen, Kung-Chao Chang, Hui-Ping Hsu, Yan-Shen Shan and Ming-Derg Lai
    Citation: BMC Cancer 2015 15:903
    Content type: Research article Published on:

  16. The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) encodes for a multifunctional receptor involved in lysosomal enzyme trafficking, fetal organogenesis, cytotoxic T cell-induced apoptosis a...

    Authors: Timothy A Jamieson, David M Brizel, J Keith Killian, Yoshihiko Oka, Hong-Seok Jang, Xiaolong Fu, Robert W Clough, Robin T Vollmer, Mitchell S Anscher and Randy L Jirtle
    Citation: BMC Cancer 2003 3:4
    Content type: Research article Published on:

  17. Ezrin, a member of the ezrin/radixin/moesin (ERM) protein family, plays a pivotal role in tumor invasion and metastasis. This study is aimed to investigate the clinicopathological significance of upregulated e...

    Authors: Jienan Kong, Yan Li, Shuangping Liu, Haidan Jin, Yongjun Shang, Chengshi Quan, Yulin Li and Zhenhua Lin
    Citation: BMC Cancer 2013 13:520
    Content type: Research article Published on:

  18. New immunotherapeutic strategies based on predictors are urgently needed. Toll-like receptor adaptor interacting with SLC15A4 on the lysosome (TASL) was recently confirmed to fulfill an important role in the i...

    Authors: Huanyu Li, Xiaoyu Sun, Yanyun Zhao, Changzhu Zhang, Kai Jiang, Jie Ren, Lijuan Xing and Miao He
    Citation: BMC Cancer 2023 23:528
    Content type: Research Published on:

  19. The prognostic significance of TP53 concurrent mutations in patients with epidermal growth factor receptor (EGFR)- or anaplastic lymphoma kinase (ALK)- mutated advanced non–small-cell lung cancer (NSCLC) who r...

    Authors: Kang Qin, Helei Hou, Yu Liang and Xiaochun Zhang
    Citation: BMC Cancer 2020 20:328
    Content type: Research article Published on:

  20. The prognosis of lung cancer with synchronous brain metastasis (LCBM) is very poor, and patients often die within a short time. However, little is known about the early mortality and related factors in patient...

    Authors: Heng Shen, Gang Deng, Qianxue Chen and Jin Qian
    Citation: BMC Cancer 2021 21:825
    Content type: Research Published on:

  22. Transporter associated with antigen processing 1 (TAP1) is a molecule involved in processing and presentation of major histocompatibility complex class I restricted antigens, including tumor-associated antigen...

    Authors: Zewei Tu, Kuangxun Li, Qiankun Ji, Yuyang Huang, Shigang Lv, Jingying Li, Lei Wu, Kai Huang and Xingen Zhu
    Citation: BMC Cancer 2023 23:133
    Content type: Research Published on:

  23. Selection of the best lymph node for dissection is a controversial topic in clinical stage-I non-small cell lung cancer (NSCLC). Here, we sought to identify the clinicopathologic predictors of regional lymph n...

    Authors: Fei Zhao, Fu-Xi Zhen, Yue Zhou, Chen-Jun Huang, Yue Yu, Jun Li, Qi-Fan Li, Cheng-Xiang Zhu, Xiao-Yu Yang, Shu-Hui You, Qian-Ge Wu, Xue-Yun Qin, Yi Liu, Liang Chen and Wei Wang
    Citation: BMC Cancer 2019 19:444
    Content type: Research article Published on:

  24. The BH3-only members of the Bcl-2 protein family have been proposed to play a key role in the control of apoptosis and in the initiation of the apoptotic pathways. In this study, we evaluated the expression of...

    Authors: Jun Sakakibara-Konishi, Satoshi Oizumi, Junko Kikuchi, Eiki Kikuchi, Hidenori Mizugaki, Ichiro Kinoshita, Hirotoshi Dosaka-Akita and Masaharu Nishimura
    Citation: BMC Cancer 2012 12:286
    Content type: Research article Published on:

  25. Background The methylation of SHOX2 and RASSF1A shows promise as a potential biomarker for the early screening of lung cancer, offering a solution to remedy the limitations of morphological diagnosis. The aim of ...

    Authors: Jiaping Zhao, Yu Lu, Xiaosha Ren, Tingting Bian, Jia Feng, Hui Sun, Lei Liu, Bin She, Yifei Liu and Honggang Ke
    Citation: BMC Cancer 2024 24:687
    Content type: Research Published on:

  26. This study aimed to evaluate the feasibility and prognostic accuracy of incorporating the number of positive lymph nodes (PLN) into the TNM staging system for non-small cell lung cancer (NSCLC) patients.

    Authors: Xiaoling Shang, Jia Liu, Zhenxiang Li, Jiamao Lin and Haiyong Wang
    Citation: BMC Cancer 2019 19:591
    Content type: Research article Published on:

  27. This study aimed to develop an innovative inflammation-nutrition biomarker score (INS) system to stratify the prognoses of patients with cancer.

    Authors: Hailun Xie, Guotian Ruan, Lishuang Wei, Heyang Zhang, Qi Zhang, Yizhong Ge, Shiqi Lin, Mengmeng Song, Xi Zhang, Xiaoyue Liu, Xiaowei Zhang, Xiangrui Li, Kangping Zhang, Ming Yang, Meng Tang, Li Deng…
    Citation: BMC Cancer 2022 22:1311
    Content type: Research Published on:

  28. Immunotherapy has made significant advances in the treatment of extensive-stage small-cell lung cancer (ES-SCLC), but data in combination with radiotherapy are scarce. This study aims to assess the safety and ...

    Authors: Lijuan Li, Dan Yang, Yanmei Min, Anyan Liao, Jing Zhao, Leilei Jiang, Xin Dong, Wei Deng, Huiming Yu, Rong Yu, Jun Zhao and Anhui Shi
    Citation: BMC Cancer 2023 23:318
    Content type: Research Published on:

  29. Lung cancer is one of the most common type of cancer and, despite significant advances in screening and diagnosis approaches, a large proportion of patients at diagnosis still present advanced stages of the di...

    Authors: Alya Boutabba, Fadoua Missaoui, Akram Dlala, Hela Kamoun, Khalil Ben Salem, Amira Gabsi, Hadhemi Rejeb, Anne Letessier, Benoit Miotto and Raja Marrakchi
    Citation: BMC Cancer 2024 24:417
    Content type: Research Published on:

  30. Colorectal cancer (CRC) is one of the most prevalent types of malignant tumours. Metastasis is the leading cause of cancer-related mortality, with lung metastases accounting for 32.9% of all metastatic CRCs. H...

    Authors: Wei Dai, Caiyao Guo, Yu Wang, Yumei Li, Renjian Xie, Junhong Wu, Baole Yao, Dong Xie, Ling He, Yingying Li, Hao Huang, Yun Wang and Shenglan Liu
    Citation: BMC Cancer 2023 23:323
    Content type: Research Published on:

  31. Whether serum lactate dehydrogenase-to-albumin ratio (LAR) influenced the outcomes of colorectal cancer (CRC) patients after radical surgery remained unclear. Therefore, this study sought to examine how LAR in...

    Authors: Xin-Peng Shu, Ying-Chun Xiang, Fei Liu, Yong Cheng, Wei Zhang and Dong Peng
    Citation: BMC Cancer 2023 23:915
    Content type: Research Published on:

  32. Immunotherapy targeting PD-1/PD-L1 has revolutionized the treatment of extensive-stage small cell lung cancer (ES-SCLC). However, clinical trials suggest differential efficacy of anti-PD-1 agents and anti-PD-L...

    Authors: Boyu Qin, Lingli Xin, Chen Liang, Lingling Li, Qi Song, Yaping Long, Xiaoling Zhang, Dan Wang, Weiwei Shi, Jing Zhang, Yi Hu, Bo Yang and Qi Xiong
    Citation: BMC Cancer 2024 24:100
    Content type: Research Published on:

  34. We recently found that epiplakin 1 (EPPK1) alterations were present in 12% of lung adenocarcinoma (LUAD) cases and were associated with a poor prognosis in early-stage LUAD when combined with other molecular a...

    Authors: Ken Arimura, Michael Kammer, S. M. Jamshedur Rahman, Chen Sheau-Chiann, Shilin Zhao, Chen Heidi, Rosana Eisenberg, Yong Zou, Sanja Antic, Bradley Richmond, Etsuko Tagaya, Eric Grogan, Pierre Massion and Fabien Maldonado
    Citation: BMC Cancer 2024 24:441
    Content type: Research Published on:

  35. Selective lateral pelvic lymph node (LPN) dissection (LPND) following neoadjuvant chemoradiotherapy (nCRT) for rectal cancer is widely recognized. This study aimed to determine the effects of nCRT before LPND ...

    Authors: Zhongshi Xie, Qichen Chen, Bo Feng, Yujuan Jiang, Xin Wang, Wei Xing and Qian Liu
    Citation: BMC Cancer 2024 24:115
    Content type: Research Published on:

  36. The role of neutrophil–lymphocyte ratio (NLR) as a predictor for survival in single fraction SBRT-treated non-small cell lung cancer (NSCLC) patients remains unclear. We performed an observational cohort study...

    Authors: Karen Huang, Sharan Prasad, Sung Jun Ma, Han Yu, Austin J. Iovoli, Mark K. Farrugia, Elizabeth U. Dexter, Todd L. Demmy, Nadia K. Malik and Anurag K. Singh
    Citation: BMC Cancer 2023 23:254
    Content type: Research Published on:

  37. To investigate how the negative regulation of CD44st by miR-138-5p affects the invasive ability of breast cancer cell lines and prognosis in postoperative breast cancer patients.

    Authors: Fang Xin Jian, Peng Xiao Bao, Wang Fu Li, Yan Hai Cui and Hang Guan Hong
    Citation: BMC Cancer 2023 23:269
    Content type: Research Published on:

  38. The Veterans Health Administration (VHA) is the largest integrated health care system in the United States (US). Among VHA patients, the rate of use of concurrent chemoradiation therapy (CCRT) among those with...

    Authors: Anna Hung, Kyung Min Lee, Julie A. Lynch, Yanhong Li, Pradeep Poonnen, Olga V. Efimova, Bradley J. Hintze, Trudy Buckingham, Candice Yong, Brian Seal, Michael J. Kelley and Shelby D. Reed
    Citation: BMC Cancer 2021 21:824
    Content type: Research Published on:

  39. The role of TNFα in cancer is complex with both pro-tumourigenic and anti-tumourigenic roles proposed. We hypothesised that anatomical microlocalisation is critical for its function.

    Authors: Chandra M Ohri, Aarti Shikotra, Ruth H Green, David A Waller and Peter Bradding
    Citation: BMC Cancer 2010 10:323
    Content type: Research article Published on:

  40. Postoperative adjuvant cisplatin-based chemotherapy had been the standard care in patients with completely resected high-risk stage IB to IIIA non-small cell lung cancer (NSCLC) for decades. However, the survi...

    Authors: Pengfei Zhao, Hongchao Zhen, Hong Zhao, Lei Zhao and Bangwei Cao
    Citation: BMC Cancer 2022 22:328
    Content type: Research Published on:

  41. Immunotherapy is a novel hotspot for the treatment of pancreatic adenocarcinoma (PAAD). However, potential biomarkers which could identify the inflamed tumor microenvironment (TME) are urgently required.

    Authors: Shuping Si, Lei Wang, Hui Cao, Yuhua Xu and Qiang Zhan
    Citation: BMC Cancer 2022 22:211
    Content type: Research Published on:

  42. The objective of this study was to evaluate the radiation dose and response in terms of local-regional progression-free survival (LRPFS) and overall survival (OS) of patients with stage IV non-small cell lung ...

    Authors: Wei-Wei Ouyang, Sheng-Fa Su, Yin-Xiang Hu, Bing Lu, Zhu Ma, Qing-Song Li, Hui-Qin Li and Yi-Chao Geng
    Citation: BMC Cancer 2014 14:491
    Content type: Research article Published on:

  44. Long non-coding RNA P73 antisense RNA 1 T (non-protein coding), also known as Lnc RNA TP73-AS1, is dysregulated in various tumors but the correlation between its expression and clinicopathological parameters a...

    Authors: Caizhi Chen, Jingjing Wang, Yeqian Feng, Ye Liang, Yan Huang and Wen Zou
    Citation: BMC Cancer 2022 22:581
    Content type: Research Published on:

  45. Recent studies have shown that immune-related adverse events (irAEs) caused by immune checkpoint inhibitors were associated with clinical benefit in patients with melanoma or lung cancer. In advanced gastric c...

    Authors: Ken Masuda, Hirokazu Shoji, Kengo Nagashima, Shun Yamamoto, Masashi Ishikawa, Hiroshi Imazeki, Masahiko Aoki, Takahiro Miyamoto, Hidekazu Hirano, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato and Narikazu Boku
    Citation: BMC Cancer 2019 19:974
    Content type: Research article Published on:

  46. Lung cancer is the most common cause of cancer related death worldwide. The majority of cases are detected at a late stage when prognosis is poor. The EarlyCDT®-Lung Test detects autoantibodies to abnormal cel...

    Authors: F. M. Sullivan, Eoghan Farmer, Frances S. Mair, Shaun Treweek, Denise Kendrick, Cathy Jackson, Chris Robertson, Andrew Briggs, Colin McCowan, Laura Bedford, Ben Young, Kavita Vedhara, Stephanie Gallant, Roberta Littleford, John Robertson, Herb Sewell…
    Citation: BMC Cancer 2017 17:187
    Content type: Study protocol Published on:

  47. Small-cell lung cancer (SCLC) is a highly aggressive and lethal malignancy that accounts for 10–15% of lung cancers, and it is generally divided into limited and extensive stage. The standard of care for patie...

    Authors: Deyu Li, Zhangzhou Huang, Jiangming Zhong, Li Lin, Guifeng Zhang, Wu Zhuang and Zhenhua Liu
    Citation: BMC Cancer 2023 23:753
    Content type: Study protocol Published on:

  48. Pathological stage IB-IIIA lung adenocarcinoma with an epidermal growth factor receptor (EGFR) mutation (Mt) has a high recurrence rate even after complete resection. However, there have been few reports on t...

    Authors: Tetsuya Isaka, Hiroyuki Ito, Tomoyuki Yokose, Haruhiro Saito, Hiroyuki Adachi, Kotaro Murakami, Jun Miura, Noritake Kikunishi and Yasushi Rino
    Citation: BMC Cancer 2022 22:966
    Content type: Research Published on:

  49. CCRT is presently the standard treatment for LA-NSCLC. RP is one of the main obstacles to the completion of thoracic radiation therapy, resulting in limited survival benefits in NSCLC patients. This research a...

    Authors: Kuifei Chen, Shuling Li, Meng Chen, Zhicheng Jin, Xuefeng Sun, Suna Zhou and Haihua Yang
    Citation: BMC Cancer 2024 24:257
    Content type: Research Published on:

  50. Despite the wide-spread use of immune checkpoint inhibitors (ICIs) in cancer chemotherapy, reports on patients developing acquired resistance (AR) to ICI therapy are scarce. Therefore, we first investigated th...

    Authors: Kazutaka Hosoya, Daichi Fujimoto, Takeshi Morimoto, Toru Kumagai, Akihiro Tamiya, Yoshihiko Taniguchi, Toshihide Yokoyama, Tadashi Ishida, Hirotaka Matsumoto, Katsuya Hirano, Ryota Kominami, Keisuke Tomii, Hidekazu Suzuki, Tomonori Hirashima, Satoshi Tanaka, Junji Uchida…
    Citation: BMC Cancer 2021 21:346
    Content type: Research article Published on:

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