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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 21 of 79

  1. Chemotherapy is an important therapeutic approach for non-small cell lung cancer (NSCLC). However, a successful long-term treatment can be prevented by the occurring of chemotherapy resistance frequently, and ...

    Authors: Jian Zhao, Wenfan Fu, Hongying Liao, Lu Dai, Zeyong Jiang, Youguang Pan, Haoda Huang, Yijun Mo, Siwen Li, Guangping Yang and Jun Yin
    Citation: BMC Cancer 2015 15:731
    Content type: Research article Published on:

  2. Urokinase plasminogen activator (uPA) is an extracellular matrix-degrading protease that is involved in the invasiveness and progression of cancer. There is good evidence that uPA expression is a clinically re...

    Authors: Ming-Chao Tsai, Yi-Hao Yen, Kuo-Chin Chang, Chao-Hung Hung, Chien-Hung Chen, Ming-Tsung Lin and Tsung-Hui Hu
    Citation: BMC Cancer 2019 19:1169
    Content type: Research article Published on:

  3. Accurate and early prognosis of disease is essential to clinical decision making, particularly in diseases, such as HCC, that are typically diagnosed at a late stage in the course of disease and therefore carr...

    Authors: Yunhong Tian, Jianlin Wu, Cristian Chagas, Yichao Du, Huan Lyu, Yunhong He, Shouliang Qi, Yong Peng and Jiani Hu
    Citation: BMC Cancer 2018 18:1187
    Content type: Research article Published on:

  4. In clinical studies, it has been observed that esophageal cancer (EC) patient prognosis can be very different even for those patients with tumors of the same TNM stage. Tumor length has been analysed as a poss...

    Authors: Zhao Yang Wang, Yuan Zhu Jiang, Wen Xiao, Xian Biao Xue, Xiang Wei Zhang and Lin Zhang
    Citation: BMC Cancer 2021 21:988
    Content type: Research article Published on:

  5. Serum carcinoembryonic antigen (CEA) levels are a predictor of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) efficacy and are associated with epidermal growth factor receptor (EGFR) gen...

    Authors: Yuan Gao, PingPing Song, Hui Li, Hui Jia and BaiJiang Zhang
    Citation: BMC Cancer 2017 17:484
    Content type: Research article Published on:

  7. Colorectal cancer (CRC) is one of the malignant tumors with the highest morbidity and mortality and poor prognosis. The mammalian gene family of Cab45/reticulocalbin/ERC-45/calumenin (CREC) consists of RCN1, R...

    Authors: Junya Ning, Min Liu, Jing Shen, Deping Wang, Lijuan Gao, Huiyu Li and Jimin Cao
    Citation: BMC Cancer 2023 23:878
    Content type: Research Published on:

  8. This study aimed to evaluate the value of chitinase activity in prognosticating the occurrence of metastasis in and prognosis of patients with colorectal cancer (CRC).

    Authors: Zhangfa Song, Engeng Chen, Jun Qian, Jianbin Xu, Gaoyang Cao, Wei Zhou, Fei Wang, Min Chen, Dengyong Xu, Xiaowei Wang, Xiaotong Hu, Zhenyu Ju, Xuefeng Huang and Xiujun Cai
    Citation: BMC Cancer 2019 19:629
    Content type: Research article Published on:

  11. Volume-based parameters, such as metabolic tumor volume (MTV) and total lesion glycolysis (TLG), on F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) are useful for predicting treatment response...

    Authors: Tomoka Kitao, Kenji Hirata, Katsumi Shima, Takashi Hayashi, Mitsunori Sekizawa, Toshiki Takei, Wataru Ichimura, Masao Harada, Keishi Kondo and Nagara Tamaki
    Citation: BMC Cancer 2016 16:576
    Content type: Research article Published on:

  12. Several previous studies have confirmed that thrombocytosis was related to reduced survival in many solid tumors. However, the prognostic significance of thrombocytosis in endometrial carcinoma (EC) was still ...

    Authors: Dan Nie, E. Yang and Zhengyu Li
    Citation: BMC Cancer 2019 19:73
    Content type: Research article Published on:

  13. Overexpression of cyclooxygenase-2 (COX-2) has been implicated in oncogenesis and progression of adenocarcinomas of the pancreatic head. The data on the prognostic importance of COX expression in these tumours...

    Authors: Ewa Pomianowska, Aasa R Schjølberg, Ole Petter F Clausen and Ivar P Gladhaug
    Citation: BMC Cancer 2014 14:458
    Content type: Research article Published on:

  14. Platelet and blood coagulation abnormalities frequently occur in cancer patients. Fibrinogen is an important hemostatic factor that regulates the hemostatic pathway. Hyperfibrinogenemia is increasing recognize...

    Authors: Xuefeng Yu, Fulan Hu, Qiang Yao, Chunfeng Li, Hongfeng Zhang and Yingwei Xue
    Citation: BMC Cancer 2016 16:480
    Content type: Research article Published on:

  16. Circular RNAs are a new class of endogenous non-coding RNA that can function as crucial regulators of diverse cellular processes. The diverse types of circular RNAs with varying cytogenetics in cancer have als...

    Authors: Zikang Zhang, Qing Xie, Dongmei He, Yuan Ling, Yuchao Li, Jiangbin Li and Hua Zhang
    Citation: BMC Cancer 2018 18:834
    Content type: Debate Published on:

  17. Apolipoprotein A1 (ApoA1) is a member of the apolipoprotein family with diverse functions. It is associated with the pathogenesis and prognosis of several types of tumors. However, the role of serum apolipopro...

    Authors: Xiaoling Huang, Ying Wang, Zhenyu Huang, Xuzheng Chen, Qiuyan Lin, Haobo Huang and Liping Fan
    Citation: BMC Cancer 2024 24:62
    Content type: Research Published on:

  18. Most NSCLCs metastasised out of the lungs at the time of diagnosis and cannot be surgically removed . Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with ...

    Authors: Qing Xia, Guojie Chen, Yanbei Ren, Tiansheng Zheng, Changxing Shen, Ming Li, Xiangyun Chen, Hong Zhai, Zhuang Li, Jianfang Xu, Aiqin Gu, Meiling Jin and Lihong Fan
    Citation: BMC Cancer 2021 21:721
    Content type: Study protocol Published on:

  19. Treatment of pulmonary recurrence from colorectal cancer involving the main bronchus usually entails palliation using interventional bronchoscopy, because the prognosis is generally very poor. Surgical experie...

    Authors: Andrea Imperatori, Nicola Rotolo, Lorenzo Dominioni, Elisa Nardecchia, Maria Cattoni, Laura Cimetti, Cristina Riva, Fausto Sessa and Daniela Furlan
    Citation: BMC Cancer 2015 15:567
    Content type: Case report Published on:

  20. Ubiquitin-specific peptidase 10 (USP10), a typical de-ubiquitinase, has been found to play a double-edged role in human cancers. Previously, we reported that the expression of USP10 was negatively correlated w...

    Authors: Zhi Zeng, Yina Li, Heng Zhou, Mingyang Li, Juan Ye, Dan Li, Yuxi Zhu, Yonggang Zhang, Xu Zhang, Yunchao Deng, Juan Li, Lijuan Gu and Jie Wu
    Citation: BMC Cancer 2024 24:773
    Content type: Research Published on:

  21. Immune-related genes (IRGs) have been confirmed to play an important role in tumorigenesis and tumor microenvironment formation in hepatocellular carcinoma (HCC). We investigated how IRGs regulates the HCC imm...

    Authors: Jialin Qu, Fenghao Sun, Yichen Hou, Haoran Qi, Xiaorong Sun and Ligang Xing
    Citation: BMC Cancer 2023 23:549
    Content type: Research Published on:

  22. Liquid biopsy can detect circulating cancer cells or tumor cell-derived DNA at various stages of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as apoptotic bodies, microvesi...

    Authors: Mickensone Andre, Allen Caobi, Jana S. Miles, Arti Vashist, Marco A. Ruiz and Andrea D. Raymond
    Citation: BMC Cancer 2024 24:322
    Content type: Review Published on:

  23. Relationship between cancer cell glycolysis and the landscape of tumor immune microenvironment in human cancers was investigated.

    Authors: Sehui Kim, Jaemoon Koh, Seung Geun Song, Jeemin Yim, Miso Kim, Bhumsuk Keam, Young Tae Kim, Jihun Kim, Doo Hyun Chung and Yoon Kyung Jeon
    Citation: BMC Cancer 2022 22:1120
    Content type: Research Published on:

  24. Suppressors of cytokine signaling (SOCS) are important negative feedback regulators of the JAK/STAT signaling pathway, and have been recently investigated for their role in the development of different cancers...

    Authors: Walid Sasi, Wen G Jiang, Anup Sharma and Kefah Mokbel
    Citation: BMC Cancer 2010 10:178
    Content type: Research article Published on:

  26. Although radiotherapy following mastectomy was demonstrated to reduce the recurring risk and improve the prognosis of patients with breast cancer, it is also notorious for comprehensive side effects, hence onl...

    Authors: Li Min, Cheng Zhang, Ruolan Ma, Xiaofan Li, Hua Yuan, Yihao Li, Ruxuan Chen, Caiyun Liu, Jianping Guo, Like Qu and Chengchao Shou
    Citation: BMC Cancer 2016 16:717
    Content type: Research article Published on:

  28. Transforming growth factor (TGF)-β plays a pivotal role in cancer progression through regulating cancer cell proliferation, invasion, and remodeling of the tumor microenvironment. Cancer-associated fibroblasts...

    Authors: Masafumi Horie, Akira Saito, Satoshi Noguchi, Yoko Yamaguchi, Mitsuhiro Ohshima, Yasuyuki Morishita, Hiroshi I Suzuki, Tadashi Kohyama and Takahide Nagase
    Citation: BMC Cancer 2014 14:580
    Content type: Research article Published on:

  29. An increasing number of studies have described the aberrant expression of homeobox (HOX) proteins in gastric cancer (GC), which is critically associated with the prognosis and clinicopathological characteristi...

    Authors: Xiao Jin, Lu Dai, Yilan Ma, Jiayan Wang, Haihao Yan, Ye Jin, Xiaojuan Zhu and Zheng Liu
    Citation: BMC Cancer 2020 20:866
    Content type: Research article Published on:

  30. Metastases to the thyroid gland are more frequent than previously thought, although most of them are occult or not clinically relevant. Overall, only 42 cases of metastases to thyroid from breast cancer have b...

    Authors: Matilde Pensabene, Brigida Stanzione, Ivana Cerillo, Giuseppe Ciancia, Immacolata Cozzolino, Raffaella Ruocco, Caterina Condello, Giuseppe Di Lorenzo, Mario Giuliano, Valeria Forestieri, Grazia Arpino, Sabino De Placido and Rossella Lauria
    Citation: BMC Cancer 2018 18:146
    Content type: Case report Published on:

  31. Circulating YB-1/p18 was detected in 78% of patients having a tumor disease. YB-1/p18 positivity was highly prevalent in all examined malignancies, including lung cancer (32/37; 87%), breast cancer (7/10; 70%), cancer

    Authors: Frank Tacke, Oliver Galm, Nicolas Kanig, Eray Yagmur, Sabine Brandt, Jonathan A Lindquist, Christiane S Eberhardt, Ute Raffetseder and Peter R Mertens
    Citation: BMC Cancer 2014 14:33
    Content type: Research article Published on:

  32. Osteoblastic bone reaction (OBR) refers to an increase in bone density at the site of bone metastasis or the appearance of new sclerotic bone lesions after anticancer treatment. OBR can be misunderstood as dis...

    Authors: Kensuke Kanaoka, Hiromitsu Sumikawa, Shunsuke Oyamada, Akihiro Tamiya, Yuji Inagaki, Yoshihiko Taniguchi, Keiko Nakao, Yoshinobu Matsuda and Kyoichi Okishio
    Citation: BMC Cancer 2023 23:834
    Content type: Research Published on:

  33. In the present study, we show that the combination of doxorubicin with the cyclin-dependent kinase inhibitor P276-00 was synergistic at suboptimal doses in the non-small cell lung carcinoma (NSCLC) cell lines ...

    Authors: Maggie J Rathos, Harshal Khanwalkar, Kavita Joshi, Sonal M Manohar and Kalpana S Joshi
    Citation: BMC Cancer 2013 13:29
    Content type: Research article Published on:

  34. Capture of cancer stage at diagnosis is important yet poorly reported by health services to population-based cancer registries. In this paper we describe current completeness of stage information for endometri...

    Authors: S. M. Evans, K. Ivanova, R. Rome, D. Cossio, CHC Pilgrim, J. Zalcberg, Y. Antill, L. Blake, A. Du Guesclin, A. Garrett, D. Giffard, N. Golobic, D. Moir, S. Parikh, A. Parisi, K. Sanday…
    Citation: BMC Cancer 2023 23:1222
    Content type: Research Published on:

  35. This retrospective study was performed to determine the prognostic potential of smoking and its combination with pre-treatment plasma Epstein-Barr virus (EBV) DNA levels in patients with nasopharyngeal carcino...

    Authors: Wanxia Li, Chao Yang, Feipeng Zhao, Junzheng Li, Zonghua Li, Ping Ouyang, Xiaofei Yuan, Shuting Wu, Yue Yuan, Linchong Cui, Huiru Feng, Danfan Lin, Zilu Chen, Juan Lu, Xiaohong Peng and Jing Chen
    Citation: BMC Cancer 2022 22:1262
    Content type: Research article Published on:

  36. The prognostic value of preoperative controlling nutritional status (CONUT) has been reported in many malignancies. In present study, we aimed to clarify the prognostic impact of CONUT in gastric cancer (GC) r...

    Authors: Xuechao Liu, Deyao Zhang, Enzi Lin, Yongming Chen, Wei Li, Yingbo Chen, Xiaowei Sun and Zhiwei Zhou
    Citation: BMC Cancer 2018 18:699
    Content type: Research article Published on:

  37. The clinical relevance of circulating tumor cell-white blood cell (CTC-WBC) clusters in cancer prognosis is a subject of ongoing debate. This study aims to unravel their contentious predictive value for patien...

    Authors: Mingguang Ju, Ziming Gao, Gaoxiang Gu, Haibo Huang, Anqi Sun, Chen Zheng, He Li, Yixiao Zhang and Kai Li
    Citation: BMC Cancer 2023 23:1224
    Content type: Research Published on:

  38. The optimal treatment for patients with brain metastasis from gestational trophoblastic neoplasia (GTN) has not been established. This study aims to investigate the clinical characteristics and the management ...

    Authors: Changji Xiao, Junjun Yang, Jing Zhao, Tong Ren, Fengzhi Feng, Xirun Wan and Yang Xiang
    Citation: BMC Cancer 2015 15:318
    Content type: Research article Published on:

  39. It was reported that tumor-expressed dickkopf-related (DKK) proteins affect micro-environment. However, the influence of DKK1 on colorectal cancer (CRC) liver oligometastases (CRCLOM) remains unclear.

    Authors: Qiaoqi Sui, Jian Zheng, Dingxin Liu, Jianhong Peng, Qingjian Ou, Jinghua Tang, Yuan Li, Lingheng Kong, Wu Jiang, Binyi Xiao, Xue Chao, Zhizhong Pan, Huizhong Zhang and Pei-Rong Ding
    Citation: BMC Cancer 2019 19:1210
    Content type: Research article Published on:

  40. Various parameters have been considered for predicting survival in pancreatic ductal adenocarcinoma. Information about western population is missing. The aim of this study is to assess the association between ...

    Authors: Mar Achalandabaso Boira, Marcello Di Martino, Carlos Gordillo, Magdalena Adrados and Elena Martín-Pérez
    Citation: BMC Cancer 2020 20:909
    Content type: Research article Published on:

  41. MicroRNAs are noncoding RNA molecules of ~ 22 nucleotides with diagnostic and therapeutic action [Curr Drug Targets, 2015. 16(12): p. 1381-403], affecting the expression of mRNAs involved in invasion, migratio...

    Authors: Olga D’Almeida, Omar Mothar, Esther Apraku Bondzie, Yolande Lieumo, Laure Tagne, Sumeet Gupta, Thomas Volkert, Stuart Levine and Jean-Bosco Tagne
    Citation: BMC Cancer 2019 19:136
    Content type: Research article Published on:

  42. Phospholipase Cγ1 (PLCγ1) is highly expressed in human tumours. Our previous studies reported that both stable and inducible PLCγ1 down-regulation can inhibit formation of breast-cancer-derived experimental lu...

    Authors: Rossano Lattanzio, Manuela Iezzi, Gianluca Sala, Nicola Tinari, Marco Falasca, Saverio Alberti, Simonetta Buglioni, Marcella Mottolese, Letizia Perracchio, Pier Giorgio Natali and Mauro Piantelli
    Citation: BMC Cancer 2019 19:747
    Content type: Research article Published on:

  43. To study the pattern and treatment outcome of rectal cancer (RC) with concurrent locoregional recurrence (LR) and distant metastasis (DM) after total mesorectal excision (TME) and to identify patient-, disease...

    Authors: Yikuan Chen, Yaqi Li, Shaobo Mo, Xiang Hu, Fangqi Liu, Sanjun Cai, Xiaoji Ma and Junjie Peng
    Citation: BMC Cancer 2022 22:1088
    Content type: Research Published on:

  44. The polycomb transcription factor Yin Yang 1 (YY1) overexpression can be causally implicated in experimental tumor growth and metastasization. To date, there is no clinical evidence of YY1 involvement in outco...

    Authors: Filomena de Nigris, Licciana Zanella, Francesco Cacciatore, Anna De Chiara, Flavio Fazioli, Gennaro Chiappetta, Gaetano Apice, Teresa Infante, Mario Monaco, Raffaele Rossiello, Gaetano De Rosa, Marco Alberghini and Claudio Napoli
    Citation: BMC Cancer 2011 11:472
    Content type: Research article Published on:

  45. This study explored the diagnostic power of preoperative circulating tumor cells (CTCs) for the presence of microvascular invasion (MVI) and the relationship between dynamic changes in postoperative CTCs and p...

    Authors: Jiangmin Zhou, Zhiwei Zhang, Honghao Zhou, Chao Leng, Bingwu Hou, Chenyang Zhou, Xinsheng Hu, Jinlin Wang and Xiaoping Chen
    Citation: BMC Cancer 2020 20:1047
    Content type: Research article Published on:

  47. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are used in treating cardiovascular diseases. Previous studies indicated that ACEIs/ARBs may benefit cancer patients by...

    Authors: Po-Chih Li, Ru-Yu Huang, Yu-Chien Yang, Kun-Pin Hsieh and Yi-Hsin Yang
    Citation: BMC Cancer 2022 22:430
    Content type: Research Published on:

  48. Chromosome 1 open reading frame 63 (C1orf63) is located on the distal short arm of chromosome 1, whose allelic loss has been observed in several human cancers. C1orf63 has been reported to be up-regulated in I...

    Authors: Chao-Qun Hong, Fan Zhang, Yan-Jie You, Wei-Li Qiu, Armando E. Giuliano, Xiao-Jiang Cui, Guo-Jun Zhang and Yu-Kun Cui
    Citation: BMC Cancer 2015 15:548
    Content type: Research article Published on:

  49. The incidence of colorectal cancer (CRC) is expected to increase by 80% in year 2035. Even though advantages in treatment of CRC have being made over the last decades, the outcome remains poor. Recently, sever...

    Authors: Nikoletta Dimitriou, Evangelos Felekouras, Ioannis Karavokyros, Andreas Alexandrou, Emmanuel Pikoulis and John Griniatsos
    Citation: BMC Cancer 2018 18:1202
    Content type: Research article Published on:

  50. Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored w...

    Authors: Sara Jansson, Pär-Ola Bendahl, Anna-Maria Larsson, Kristina E. Aaltonen and Lisa Rydén
    Citation: BMC Cancer 2016 16:433
    Content type: Research article Published on:

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