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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. We evaluated the safety and efficacy of induction chemotherapy with bevacizumab followed by maintenance chemotherapy with bevacizumab for advanced non-small cell lung cancer (NSCLC) in this multicenter phase I...

    Authors: Yasuhiro Tsutani, Yoshihiro Miyata, Takeshi Masuda, Kazunori Fujitaka, Mihoko Doi, Yoshikazu Awaya, Shoichi Kuyama, Soichi Kitaguchi, Kazuhiro Ueda, Noboru Hattori and Morihito Okada
    Citation: BMC Cancer 2018 18:1231
    Content type: Research article Published on:

  2. Immunosenescence biomarkers and peripheral blood parameters are evaluated separately as possible predictive markers of immunotherapy. Here, we illustrate the use of a causal inference model to identify predict...

    Authors: Patricia Lorenzo-Luaces, Lizet Sanchez, Danay Saavedra, Tania Crombet, Wim Van der Elst, Ariel Alonso, Geert Molenberghs and Agustin Lage
    Citation: BMC Cancer 2020 20:772
    Content type: Research article Published on:

  3. Immune checkpoint inhibitors (ICI) combined with chemotherapy are efficacious for treating advanced non-small cell lung cancer (NSCLC); however, the effectiveness of this approach in the malignant pleural effu...

    Authors: Qi Wei, Taibing Deng, Junhua Wu, Hao Zeng, Chang Qi, Sihan Tan, Yuanyuan Zhang, Qin Huang, Xin Pu, Weiguo Xu, Weimin Li, Panwen Tian and Yalun Li
    Citation: BMC Cancer 2024 24:393
    Content type: Research Published on:

  4. The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dacomitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC)...

    Authors: Wen-Chien Cheng, Chi-Chien Lin, Wei-Chih Liao, Yu-Chao Lin, Chia-Hung Chen, Hung-Jen Chen, Chih-Yen Tu and Te-Chun Hsia
    Citation: BMC Cancer 2024 24:228
    Content type: Research Published on:

  5. Leptomeningeal metastasis (LM) is a severe complication of advanced non-small cell lung cancer (NSCLC). This retrospective study aimed to investigate the potential use of osimertinib for preventing LM in patie...

    Authors: Xia Wang, Jing Cai, Zhimin Zeng and Anwen Liu
    Citation: BMC Cancer 2021 21:873
    Content type: Research Published on:

  6. This study aimed to evaluate the prognostic significance of postoperative Creatine Kinase type M and B (CK-MB) to total Creatine Kinase (CK) ratio (CK-MB/CK) in colorectal cancer (CRC) patients after radical r...

    Authors: Lubei Rao, Pingyao Xu, Guiji Zhang, Ruiling Zu, Yajun Luo, Kaijiong Zhang, Ying Yang, Dongsheng Wang, Shuya He, Huaichao Luo and Bo Ye
    Citation: BMC Cancer 2024 24:543
    Content type: Research Published on:

  7. Treatment of locally advanced non-small-cell lung cancer is based on a combined approach. To study the impact of trimodal therapy for stage III-N2 NSCLC a single centre retrospective evaluation focusing on sur...

    Authors: Vasileios Askoxylakis, Judith Tanner, Jutta Kappes, Hans Hoffmann, Nils H Nicolay, Harald Rief, Juergen Debus, Michael Thomas and Marc Bischof
    Citation: BMC Cancer 2014 14:572
    Content type: Research article Published on:

  8. The initial therapeutic strategy for hormone receptor-positive (HR+), HER2-negative (HER2-) breast cancer is based on the first metastatic site; however, little evidence is available regarding the influence of...

    Authors: Jun Yamamura, Shunji Kamigaki, Junya Fujita, Hiroki Osato, Hironobu Manabe, Yumiko Tanaka, Wataru Shinzaki, Yukihiko Hashimoto and Yoshifumi Komoike
    Citation: BMC Cancer 2021 21:476
    Content type: Research article Published on:

  9. Kinase insert domain-containing receptor (KDR) plays a critical role in the metastasis of cancer and is used as a molecular target in cancer therapy. We investigated the characteristics of the -271 G>A polymor...

    Authors: She-Juan An, Zhi-Hong Chen, Qiu-Xiong Lin, Jian Su, Hua-Jun Chen, Jia-Ying Lin and Yi-Long Wu
    Citation: BMC Cancer 2009 9:144
    Content type: Research article Published on:

  10. Cyclooxygenase (COX)-2 has been implicated in tumour progression, angiogenesis and metastasis in non-small cell lung cancer (NSCLC). We speculated that inhibition of COX-2 activity might reduce expression of t...

    Authors: Yong Ming Zhu, Nor Saadah M Azahri, Danny CW Yu and Penella J Woll
    Citation: BMC Cancer 2008 8:218
    Content type: Research article Published on:

  11. Concurrent chemoradiotherapy (CCRT) has become the cornerstone of treatment for patients with locally advanced non-small cell lung cancer (LA-NSCLC). The aim of this study was to compare the efficacies and tox...

    Authors: Qiangqiang Zheng, Shihui Min and Yunfeng Zhou
    Citation: BMC Cancer 2022 22:674
    Content type: Research article Published on:

  12. Many studies have recently reported the association of concomitant medications with the response and survival in patients with non-small-cell lung cancer (NSCLC) treated with cancer immunotherapy. However, the...

    Authors: Kazuki Takada, Mototsugu Shimokawa, Shinkichi Takamori, Shinichiro Shimamatsu, Fumihiko Hirai, Tetsuzo Tagawa, Tatsuro Okamoto, Motoharu Hamatake, Yuko Tsuchiya-Kawano, Kohei Otsubo, Koji Inoue, Yasuto Yoneshima, Kentaro Tanaka, Isamu Okamoto, Yoichi Nakanishi and Masaki Mori
    Citation: BMC Cancer 2022 22:503
    Content type: Research article Published on:

  14. The purpose of this study was to review patient characteristics and evaluate the potential factors affecting prognosis in cases of brain metastasis (BM) from colorectal cancer (CRC).

    Authors: Xiao-Dong Gu, Yan-Tao Cai, Yi-Ming Zhou, Zhen-Yang Li, Jian-Bin Xiang and Zong-You Chen
    Citation: BMC Cancer 2015 15:902
    Content type: Research article Published on:

  15. Studies have indicated that individuals taking aspirin have a reduced risk of cancers and have also established chemo-preventive benefit of aspirin in colorectal cancer. However, research on the association be...

    Authors: Min-Chun Chuang, Yao-Hsu Yang, Meng-Jer Hsieh, Yu-Ching Lin, Tsung-Ming Yang, Pau-Chung Chen and Ming-Szu Hung
    Citation: BMC Cancer 2021 21:1257
    Content type: Research Published on:

  16. Although survival based outcomes of lung cancer patients have been well developed, institutional transition of cancer care, that is, when patients transfer from primary visiting hospitals to other hospitals, a...

    Authors: Kyu-Tae Han, Jongwha Chang, Dong-Woo Choi, Seungju Kim, Dong Jun Kim, Yoon-Jung Chang and Sun Jung Kim
    Citation: BMC Cancer 2022 22:452
    Content type: Research Published on:

  17. The role of remission status in limited disease (LD) small-cell lung cancer (SCLC) patients treated with definitive chemoradiotherapy (CRT) remains to be finally clarified.

    Authors: Farkhad Manapov, Maximilian Niyazi, Sabine Gerum, Olarn Roengvoraphoj, Chukwuka Eze, Minglun Li, Guido Hildebrandt, Rainer Fietkau, Gunther Klautke and Claus Belka
    Citation: BMC Cancer 2016 16:216
    Content type: Research article Published on:

  18. The treatment for lung oligometastasis from colorectal cancer (CRC) remains challenging. This retrospective study aimed to compare the local tumor control, survival and procedure-related complications in CRC p...

    Authors: Yuliang Li, Zitong Chen, Shuhui Tian, Xujian Han, Changjun Wang, Yongzheng Wang and Bin Liu
    Citation: BMC Cancer 2024 24:481
    Content type: Research Published on:

  19. Chaperonin-containing tailless complex polypeptide 1 (TCP1) subunit 3 (CCT3) has tumor-promoting effects in lung adenocarcinoma (LUAD). This study aims to investigate the molecular mechanisms of CCT3 in LUAD o...

    Authors: Junfeng Huang, Bingqi Hu, Ying Yang, Huanhuan Liu, Xingyu Fan, Jing Zhou and Liwen Chen
    Citation: BMC Cancer 2023 23:241
    Content type: Research Published on:

  20. MicroRNAs (miRNAs) are short, non-coding RNAs (~22 nt) that play important roles in the pathogenesis of human diseases by negatively regulating gene expression. Although miR-196a has been implicated in several...

    Authors: Xiang-hua Liu, Kai-hua Lu, Ke-ming Wang, Ming Sun, Er-bao Zhang, Jin-song Yang, Dan-dan Yin, Zhi-li Liu, Jing Zhou, Zhi-jun Liu, Wei De and Zhao-xia Wang
    Citation: BMC Cancer 2012 12:348
    Content type: Research article Published on:

  21. The increasing role of exercise training in cancer care is built on evidence that exercise can reduce side effects of treatment, improve physical functioning and quality of life. We and others have shown in mo...

    Authors: Gitte Holmen Olofsson, Marta Kramer Mikkelsen, Anne-Mette Ragle, Anne Birgitte Christiansen, Anne Pries Olsen, Lise Heide-Ottosen, Cecilia Bech Horsted, Cia Moon Scharbau Pedersen, Lotte Engell-Noerregaard, Torben Lorentzen, Gitte Fredberg Persson, Anders Vinther, Dorte Lisbet Nielsen and Per thor Straten
    Citation: BMC Cancer 2022 22:246
    Content type: Study protocol Published on:

  22. The clinical value of combined local radiation and epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) for medically inoperable and TKI-naïve early-stage lung adenocarcinoma patients with...

    Authors: Yuemei Sun, Mengwan Wu, Mingxiu Zhou, Xing Luo, Yan Guo, Hansong Bai, Zican Zhang, Wei Tian, Xiaoshan Wang, Yifeng Bai, Xueqiang Zhu, Haixia Pan, Ying Deng, Honglin Hu, Jianling Xia, Xinbao Hao…
    Citation: BMC Cancer 2020 20:646
    Content type: Research article Published on:

  23. Sorafenib is a multi-targeted kinase inhibitor with a demonstrated activity in renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC), and it is currently used for the treatment of these pathologies. On...

    Authors: Andrea Casadei Gardini, Elisa Chiadini, Luca Faloppi, Giorgia Marisi, Angelo Delmonte, Mario Scartozzi, Cristian Loretelli, Alessandro Lucchesi, Devil Oboldi, Alessandra Dubini, Giovanni Luca Frassineti and Paola Ulivi
    Citation: BMC Cancer 2016 16:429
    Content type: Case report Published on:

  24. Docetaxel monotherapy is one of the standard treatments for non-small-cell lung cancer in elderly patients. The addition of bevacizumab to docetaxel seems promising; however, the feasibility of this combinatio...

    Authors: Yusuke Takagi, Yukio Hosomi, Fumihiro Oshita, Hiroaki Okamoto, Nobuhiko Seki, Koichi Minato, Hiromi Aono, Kouzo Yamada, Yusuke Okuma, Naoya Hida, Takahiko Sakamoto, Yosuke Miura, Makiko Yomota, Akira Satoh, Hideo Kunitoh, Kentaro Sakamaki…
    Citation: BMC Cancer 2015 15:740
    Content type: Research article Published on:

  25. Excision repair cross-complementing group 1 (ERCC1) and group 2 (ERCC2), and X-ray repair cross-complementing group 1 (XRCC1) proteins play important roles in the repair of DNA damage and adducts. Single nucle...

    Authors: Zhihua Yin, Baosen Zhou, Qincheng He, Mingchuan Li, Peng Guan, Xuelian Li, Zeshi Cui, Xiaoxia Xue, Meng Su, Rui Ma, Weijun Bai, Shuyue Xia, Yanduo Jiang, Shun Xu, Yi Lv and Xun Li
    Citation: BMC Cancer 2009 9:439
    Content type: Research article Published on:

  26. Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar ...

    Authors: Roberto Ruiz-Cordero, Junsheng Ma, Abha Khanna, Genevieve Lyons, Waree Rinsurongkawong, Roland Bassett, Ming Guo, Mark J. Routbort, Jianjun Zhang, Ferdinandos Skoulidis, John Heymach, Emily B. Roarty, Zhenya Tang, L. Jeffrey Medeiros, Keyur P. Patel, Rajyalakshmi Luthra…
    Citation: BMC Cancer 2020 20:83
    Content type: Research article Published on:

  27. Recently studies have demonstrated that the long non-coding RNA (lncRNA) metastasis associated lung adenocarcinoma transcript 1 (MALAT1) may participate in the development and progression of lung cancer. In th...

    Authors: Jian-Zhong Wang, Jing-Jun Xiang, Li-Ge Wu, Yan-Sen Bai, Zhuo-Wang Chen, Xiang-Qian Yin, Qing Wang, Wen-Hao Guo, Ying Peng, Huan Guo and Ping Xu
    Citation: BMC Cancer 2017 17:167
    Content type: Research article Published on:

  28. Recent studies have shown that miR-372 plays important roles in hepatocellular carcinoma (HCC) progression. However, results have been conflicting regarding its expression levels and role in HCC.

    Authors: Gang Wu, Yawei Wang, Xiaojun Lu, Hui He, Haiyang Liu, Xiangyu Meng, Shuguan Xia, Kunming Zheng and Boqian Liu
    Citation: BMC Cancer 2015 15:182
    Content type: Research article Published on:

  30. E2F1 has been confirmed to be highly expressed in a variety of cancers. To better understand the prognostic value of E2F1 in cancer patients, this study was conducted to comprehensively evaluate the prognostic...

    Authors: Jingjing Li, Wen Bi, Fang Lu, Bei Pan, Mengqiu Xiong, Lubanga Nasifu, Zhenlin Nie and Bangshun He
    Citation: BMC Cancer 2023 23:509
    Content type: Research Published on:

  31. It was demonstrated that multifunctional protein APE1 (Apurinic/apyrimidinic endonuclease 1) is closely related to tumor immune microenvironment in a number of investigations, Meanwhile, the abundance of tumor...

    Authors: Yanping Li, Xiaolong Zhao, He Xiao, Bo Yang, Jie Liu, Wen Rao, Xiaoyan Dai, Mengxia Li, Nan Dai, Yuxin Yang and Dong Wang
    Citation: BMC Cancer 2021 21:233
    Content type: Research article Published on:

  32. Nutritional support, including nutritional counseling and oral nutritional supplements (ONS), has been recommended as a first-line strategy in patients with non-small cell lung cancer (NSCLC). Evidence on the ...

    Authors: Riccardo Caccialanza, Emanuele Cereda, Francesco Agustoni, Catherine Klersy, Amanda Casirati, Elisabetta Montagna, Simona Carnio, Silvia Novello, Michele Milella, Sara Pilotto, Ilaria Trestini, Lucio Buffoni, Alessandra Ferrari and Paolo Pedrazzoli
    Citation: BMC Cancer 2022 22:1212
    Content type: Study protocol Published on:

  33. Most patients with intrahepatic cholangiocarcinoma (ICC) have developed distant metastasis at the time of diagnosis, while there is rear related nomogram to predict the prognosis.

    Authors: Chen Yuan, Shubing Zou, Kai Wang and Zhigang Hu
    Citation: BMC Cancer 2024 24:227
    Content type: Research Published on:

  34. The cytokine Osteopontin is a mediator of tumor progression and cancer metastasis. In 2006, we reported that (in addition to the full-length form -a) splice variants of Osteopontin (forms -b and -c) are produc...

    Authors: Yu An, Gulimirerouzi Fnu, Changchun Xie and Georg F. Weber
    Citation: BMC Cancer 2023 23:373
    Content type: Research article Published on:

  35. Nonseminomatous germ cell tumors (NSGCTs) represent one of the main groups of germ cell tumors (GCTs), and they have a more invasive course than seminomatous GCTs. Human immunodeficiency virus (HIV) positivity...

    Authors: Ruili Li and Hongjun Li
    Citation: BMC Cancer 2019 19:244
    Content type: Case report Published on:

  36. Treatment outcomes of advanced non-small cell lung cancer (NSCLC) have substantially improved with immune checkpoint inhibitors (ICI), although only approximately 19% of patients respond to immunotherapy alone...

    Authors: Andrew F. Nyein, Shahla Bari, Stephanie Hogue, Yayi Zhao, Bradley Maller, Sybil Sha, Maria F. Gomez, Dana E. Rollison and Lary A. Robinson
    Citation: BMC Cancer 2022 22:101
    Content type: Research Published on:

  37. Multicenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organization...

    Authors: Yuan Liu, Jinzao Huang, Jyh-Cheng Chen, Wei Chen, Yuteng Pan and Jianfeng Qiu
    Citation: BMC Cancer 2024 24:688
    Content type: Research Published on:

  38. The purpose of the PROLUCA study is to investigate the efficacy of preoperative and early postoperative rehabilitation in a non-hospital setting in patients with operable lung cancer with special focus on exer...

    Authors: Maja S Sommer, Karen Trier, Jette Vibe-Petersen, Malene Missel, Merete Christensen, Klaus R Larsen, Seppo W Langer, Carsten Hendriksen, Paul Clementsen, Jesper H Pedersen and Henning Langberg
    Citation: BMC Cancer 2014 14:404
    Content type: Study protocol Published on:

  39. Post-surgical prognosis is usually poor for combined hepatocellular cholangiocarcinoma (CHCC-CC), a rare primary liver cancer. Although midkine (MK) is a prognostic biomarker for several known cancers, it is n...

    Authors: Ming-Chun Ma, Yi-Ju Chen, Tai-Jan Chiu, Jui Lan, Chien-Ting Liu, Yi-Ching Chen, Hsin-Ho Tien and Yen-Yang Chen
    Citation: BMC Cancer 2018 18:227
    Content type: Research article Published on:

  40. Immune checkpoint inhibitors (ICIs) can lead to life-threatening pneumonitis, and pre-existing interstitial lung abnormalities (ILAs) are a risk factor for checkpoint inhibitor pneumonitis (CIP). However, the ...

    Authors: Xinyue Wang, Jinkun Zhao, Ting Mei, Wenting Liu, Xiuqiong Chen, Jingya Wang, Richeng Jiang, Zhaoxiang Ye and Dingzhi Huang
    Citation: BMC Cancer 2024 24:269
    Content type: Research Published on:

  41. Several different gene expression signatures have been proposed to predict response to therapy and clinical outcome in lung adenocarcinoma. Herein, we investigate if elements of published gene sets can be repr...

    Authors: Jens Neumann, Friedrich Feuerhake, Gian Kayser, Thorsten Wiech, Konrad Aumann, Bernward Passlick, Paul Fisch, Martin Werner and Axel zur Hausen
    Citation: BMC Cancer 2010 10:77
    Content type: Research article Published on:

  42. Cuproptosis, an emerging form of programmed cell death, has recently been identified. However, the association between cuproptosis-related long non-coding RNA (lncRNA) signature and the prognosis in prostate c...

    Authors: Xiaofeng Cheng, Zhenhao Zeng, Heng Yang, Yujun Chen, Yifu Liu, Xiaochen Zhou, Cheng Zhang and Gongxian Wang
    Citation: BMC Cancer 2023 23:105
    Content type: Research Published on:

  43. Paclitaxel liposome (Lipusu) is known to be effective in non-small cell lung cancer (NSCLC) as first-line treatment. This study aimed to evaluate the effectiveness and safety of paclitaxel liposome based chemo...

    Authors: Ran Li, Hongge Liang, Jun Li, Zhenyu Shao, Donghong Yang, Jing Bao, Keqiang Wang, Wen Xi, Zhancheng Gao, Renhua Guo and Xinlin Mu
    Citation: BMC Cancer 2024 24:107
    Content type: Research Published on:

  44. The mean platelet volume/platelet count ratio (MPV/PC) ratio based on the preoperative peripheral MPV and PCcan be used to predict the prognosis of multiple malignant tumors.

    Authors: Qicheng Deng, Qifang Long, Yanan Liu, Zhujuan Yang, Yibei Du and Xin Chen
    Citation: BMC Cancer 2021 21:1282
    Content type: Research Published on:

  45. A primary pulmonary invasive mucinous adenocarcinoma (IMA) is a rare subtype of invasive adenocarcinoma of the lung. The prognosis of advanced IMA depending on chemotherapy regimen has not been fully investiga...

    Authors: Yoon Jung Jang, Dong-gon Hyun, Chang-Min Choi, Dae Ho Lee, Sang-We Kim, Shinkyo Yoon, Woo Sung Kim, Wonjun Ji and Jae Cheol Lee
    Citation: BMC Cancer 2021 21:731
    Content type: Research article Published on:

  46. This study aimed to analyze the pattern of lymphogenous and hematogenous metastases in patients with stage IVb thymic carcinomas and identify prognostic factors for their survivals.

    Authors: Yu Yang, Xing-Wen Fan, Hong-Bing Wang, Yin Xu, Dou-Dou Li and Kai-Liang Wu
    Citation: BMC Cancer 2017 17:217
    Content type: Research article Published on:

  48. Cutaneous squamous cell carcinoma (SCC) is associated with underlying immunosuppression, so it may be a prognostic marker in patients with subsequent cancer. We therefore conducted a nationwide population-base...

    Authors: Sigrun Alba Johannesdottir, Timothy L Lash, Annette Østergaard Jensen, Dóra Körmendiné Farkas and Anne Braae Olesen
    Citation: BMC Cancer 2012 12:126
    Content type: Research article Published on:

  49. The aim of this study was to assess the diagnostic utility of metabolic parameters on fluorine-18-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/computed tomography (CT) for predicting lymph n...

    Authors: Keita Nakanishi, Shota Nakamura, Tomoshi Sugiyama, Yuka Kadomatsu, Harushi Ueno, Masaki Goto, Naoki Ozeki, Takayuki Fukui, Shingo Iwano and Toyofumi Fengshi Chen-Yoshikawa
    Citation: BMC Cancer 2021 21:983
    Content type: Research Published on:

  50. Gastric cancer (GC) is one of the most prevalent malignant tumors in Asian countries. Studies have proposed that lncRNAs can be used as diagnostic and prognostic indicators of GC due to the high specificity of...

    Authors: Shuyu Xu, Wenlong Chen, Yiwen Wang, Yuxin Zhang, Rong Xia, Jiemiao Shen, Xing Gong, Yinyin Liang, Jiayi Xu, Hua Tang, Tie Zhao, Yi Zhang, Tao Chen and Chao Wang
    Citation: BMC Cancer 2022 22:721
    Content type: Research Published on:

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