Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.
Article
Google Scholar
Bruix J, Sherman M. American Association for the Study of liver D. management of hepatocellular carcinoma: an update. Hepatology. 2011;53(3):1020–2.
Article
Google Scholar
Dutkowski P, Linecker M, DeOliveira ML, Mullhaupt B, Clavien PA. Challenges to liver transplantation and strategies to improve outcomes. Gastroenterology. 2015;148(2):307–23.
Article
Google Scholar
Sugawara Y, Hibi T. Surgical treatment of hepatocellular carcinoma. Biosci Trends. 2021;15(3):138–41.
Article
Google Scholar
Gunsar F. Liver transplantation for hepatocellular carcinoma beyond the Milan criteria. Exp Clin Transplant. 2017;15(Suppl 2):59–64.
Google Scholar
Barreto SG, Strasser SI, McCaughan GW, Fink MA, Jones R, McCall J, et al. Expansion of liver transplantation criteria for hepatocellular carcinoma from Milan to UCSF in Australia and New Zealand and justification for Metroticket 2.0. Cancers (Basel). 2022;14(11):2777.
Article
CAS
Google Scholar
Kim WR, Mannalithara A, Heimbach JK, Kamath PS, Asrani SK, Biggins SW, et al. MELD 3.0: the model for end-stage liver disease updated for the modern era. Gastroenterology. 2021;161(6):1887–1895 e1884.
Article
Google Scholar
Zheng SS, Xu X, Wu J, Chen J, Wang WL, Zhang M, et al. Liver transplantation for hepatocellular carcinoma: Hangzhou experiences. Transplantation. 2008;85(12):1726–32.
Article
CAS
Google Scholar
Shimamura T, Goto R, Watanabe M, Kawamura N, Takada Y. Liver transplantation for hepatocellular carcinoma: how should we improve the thresholds? Cancers (Basel). 2022;14(2):419.
Article
CAS
Google Scholar
Karsch-Bluman A, Benny O. Necrosis in the tumor microenvironment and its role in Cancer recurrence. Adv Exp Med Biol. 2020;1225:89–98.
Article
CAS
Google Scholar
Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev. 2007;26(2):225–39.
Article
CAS
Google Scholar
Atanasov G, Dietel C, Feldbrugge L, Benzing C, Krenzien F, Brandl A, et al. Tumor necrosis and infiltrating macrophages predict survival after curative resection for cholangiocarcinoma. Oncoimmunology. 2017;6(8):e1331806.
Article
Google Scholar
Kuroe T, Watanabe R, Kojima M, Morisue R, Sugano M, Kuwata T, et al. Evaluation of the morphological features and unfavorable prognostic impact of dirty necrosis in renal cell carcinoma. J Cancer Res Clin Oncol. 2021;147(4):1089–100.
Article
Google Scholar
Tata A, Woolman M, Ventura M, Bernards N, Ganguly M, Gribble A, et al. Rapid detection of necrosis in breast Cancer with desorption electrospray ionization mass spectrometry. Sci Rep. 2016;6:35374.
Article
CAS
Google Scholar
Wei T, Zhang XF, Bagante F, Ratti F, Marques HP, Silva S, et al. Tumor necrosis impacts prognosis of patients undergoing curative-intent hepatocellular carcinoma. Ann Surg Oncol. 2021;28(2):797–805.
Article
Google Scholar
Ye Q, Zhang Q, Tian Y, Zhou T, Ge H, Wu J, et al. Method of tumor pathological micronecrosis quantification via deep learning from label fuzzy proportions. IEEE J Biomed Health Inform. 2021;25(9):3288–99.
Article
Google Scholar
Wang Y, Ge H, Hu M, Pan C, Ye M, Yadav DK, et al. Histological tumor micronecrosis in resected specimens after R0 hepatectomy for hepatocellular carcinomas is a factor in determining adjuvant TACE: a retrospective propensity score-matched study. Int J Surg. 2022;105:106852.
Article
Google Scholar
Cong WM, Bu H, Chen J, Dong H, Zhu YY, Feng LH, et al. Practice guidelines for the pathological diagnosis of primary liver cancer: 2015 update. World J Gastroenterol. 2016;22(42):9279–87.
Article
Google Scholar
Le NQK, Do DT, Nguyen TT, Le QA. A sequence-based prediction of Kruppel-like factors proteins using XGBoost and optimized features. Gene. 2021;787:145643.
Article
CAS
Google Scholar
Le NQK, Kha QH, Nguyen VH, Chen YC, Cheng SJ, Chen CY. Machine learning-based Radiomics signatures for EGFR and KRAS mutations prediction in non-small-cell lung Cancer. Int J Mol Sci. 2021;22(17):9254.
Article
Google Scholar
Mandrekar JN. Receiver operating characteristic curve in diagnostic test assessment. J Thorac Oncol. 2010;5(9):1315–6.
Article
Google Scholar
Richards CH, Mohammed Z, Qayyum T, Horgan PG, McMillan DC. The prognostic value of histological tumor necrosis in solid organ malignant disease: a systematic review. Future Oncol. 2011;7(10):1223–35.
Article
CAS
Google Scholar
Atanasov G, Schierle K, Hau HM, Dietel C, Krenzien F, Brandl A, et al. Prognostic significance of tumor necrosis in hilar Cholangiocarcinoma. Ann Surg Oncol. 2017;24(2):518–25.
Article
Google Scholar
Kollmann D, Selzner N, Selzner M. Bridging to liver transplantation in HCC patients. Langenbeck's Arch Surg. 2017;402(6):863–71.
Article
Google Scholar
Lee SW, Yen CL, Cheng YC, Shun Yang S, Lee TY. The radiological prognostic factors of transcatheter arterial chemoembolization to hepatocellular carcinoma. Medicine (Baltimore). 2022;101(41):e30875.
Article
CAS
Google Scholar
Kardashian A, Florman SS, Haydel B, Ruiz RM, Klintmalm GB, Lee DD, Taner CB, Aucejo F, Tevar AD, Humar A, Verna EC, Halazun KJ, Chapman WC, Vachharajani N, Hoteit M, Levine MH, Nguyen MH, Melcher ML, Langnas AN, Carney CA, Mobley C, Ghobrial M, Amundsen B, Markmann JF, Sudan DL, Jones CM, Berumen J, Hemming AW, Hong JC, Kim J, Zimmerman MA, Nydam TL, Rana A, Kueht ML, Fishbein TM, Markovic D, Busuttil RW, Agopian VG. Liver transplantation outcomes in a U.S. multicenter cohort of 789 patients with hepatocellular carcinoma presenting beyond Milan criteria. Hepatology 2020, 72(6):2014–2028.
Google Scholar
Najmi Varzaneh F, Pandey A, Aliyari Ghasabeh M, Shao N, Khoshpouri P, Pandey P, et al. Prediction of post-TACE necrosis of hepatocellular carcinoma usingvolumetric enhancement on MRI and volumetric oil deposition on CT, with pathological correlation. Eur Radiol. 2018;28(7):3032–40.
Article
Google Scholar
Yao FY, Kerlan RK Jr, Hirose R, Davern TJ 3rd, Bass NM, Feng S, et al. Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis. Hepatology. 2008;48(3):819–27.
Article
Google Scholar
Gyori GP, Felsenreich DM, Silberhumer GR, Soliman T, Berlakovich GA. Multimodality locoregional treatment strategies for bridging HCC patients before liver transplantation. Eur Surg. 2017;49(5):236–43.
Article
Google Scholar
Clavien PA, Lesurtel M, Bossuyt PM, Gores GJ, Langer B, Perrier A, Group OLTfHC. Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report. Lancet Oncol. 2012;13(1):e11–22.
Article
Google Scholar
Chaiteerakij R, Zhang X, Addissie BD, Mohamed EA, Harmsen WS, Theobald PJ, et al. Combinations of biomarkers and Milan criteria for predicting hepatocellular carcinoma recurrence after liver transplantation. Liver Transpl. 2015;21(5):599–606.
Article
Google Scholar
Mazzaferro V, Bhoori S, Sposito C, Bongini M, Langer M, Miceli R, et al. Milan criteria in liver transplantation for hepatocellular carcinoma: an evidence-based analysis of 15 years of experience. Liver Transpl. 2011;17(Suppl 2):S44–57.
Article
Google Scholar
Lee S, Kim KW, Jeong WK, Kim MJ, Choi GH, Choi JS, et al. Gadoxetic acid-enhanced MRI as a predictor of recurrence of HCC after liver transplantation. Eur Radiol. 2020;30(2):987–95.
Article
Google Scholar
Luo X, Leanza J, Massie AB, Garonzik-Wang JM, Haugen CE, Gentry SE, et al. MELD as a metric for survival benefit of liver transplantation. Am J Transplant. 2018;18(5):1231–7.
Article
Google Scholar
Mazzaferro V, Sposito C, Zhou J, Pinna AD, De Carlis L, Fan J, et al. Metroticket 2.0 model for analysis of competing risks of death after liver transplantation for hepatocellular carcinoma. Gastroenterology. 2018;154(1):128–39.
Article
Google Scholar
Agopian VG, Harlander-Locke M, Zarrinpar A, Kaldas FM, Farmer DG, Yersiz H, et al. A novel prognostic nomogram accurately predicts hepatocellular carcinoma recurrence after liver transplantation: analysis of 865 consecutive liver transplant recipients. J Am Coll Surg. 2015;220(4):416–27.
Article
Google Scholar
Huang D, Shen Y, Zhang W, Guo C, Liang T, Bai X. A preoperative nomogram predicts prognosis of patients with hepatocellular carcinoma after liver transplantation: a multicenter retrospective study. BMC Cancer. 2021;21(1):280.
Article
CAS
Google Scholar
Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science. 2011;331(6024):1565–70.
Article
CAS
Google Scholar
Ehling J, Bartneck M, Wei X, Gremse F, Fech V, Mockel D, et al. CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis. Gut. 2014;63(12):1960–71.
Article
CAS
Google Scholar
Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, et al. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology. 2009;50(1):261–74.
Article
CAS
Google Scholar
Liu H, Ling CC, Yeung WHO, Pang L, Liu J, Zhou J, et al. Monocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling. Cell Death Dis. 2021;12(5):489.
Article
CAS
Google Scholar
Ouzounova M, Lee E, Piranlioglu R, El Andaloussi A, Kolhe R, Demirci MF, et al. Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade. Nat Commun. 2017;8:14979.
Article
CAS
Google Scholar
Bertout JA, Patel SA, Simon MC. The impact of O2 availability on human cancer. Nat Rev Cancer. 2008;8(12):967–75.
Article
CAS
Google Scholar
Chen J, Chen J, Huang J, Li Z, Gong Y, Zou B, et al. HIF-2alpha upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway. Aging (Albany NY). 2019;11(23):10839–60.
Article
CAS
Google Scholar
Kim I, Choi S, Yoo S, Lee M, Kim IS. Cancer-associated fibroblasts in the hypoxic tumor microenvironment. Cancers (Basel). 2022;14(14):3321.
Article
CAS
Google Scholar
Joshi S, Singh AR, Zulcic M, Durden DL. A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1alpha and HIF2alpha stability and tumor growth, angiogenesis, and metastasis. Mol Cancer Res. 2014;12(10):1520–31.
Article
CAS
Google Scholar