Table 3 Univariate and multivariate analyses of prognostic factors of RFS in patients without preoperative anti-tumor treatment

Age

1.005 (0.972–1.039)

0.776

Gender

2.440 (0.589–10.116)

0.219

HBV infection

1.659 (0.591–4.656)

0.336

AFP > 400 ng/mL

1.909 (0.986–3.694)

0.055

1.032 (0.451–2.363)

0.941

RDW

1.067 (0.973–1.170)

0.166

NLR

1.052 (1.019–1.086)

0.002

1.022 (0.983–1.062)

0.273

INR

0.906 (0.340–2.410)

0.843

Size of the largest tumor

2.885 (1.556–5.347)

0.001

2.115 (0.996–4.495)

0.051

Tumor number

4.809 (2.558–9.040)

<  0.001

2.905 (1.227–6.875)

0.015

Poor differentiation

4.032 (2.121–7.665)

<  0.001

1.894 (0.895–4.009)

0.095

Macrovascular invasion

4.521 (2.429–8.415)

<  0.001

2.360 (0.919–6.058)

0.074

Child-Pugh class

0.039

0.004

 A (5–6)

Reference

Reference

 B (7–9)

2.606 (0.990–6.861)

0.052

6.692 (2.012–22.262)

0.002

 C (≥ 10)

3.834 (1.364–10.776)

0.011

8.160 (2.279–29.212)

0.001

Micronecrosis

3.021 (1.270–7.184)

0.012

1.482 (0.588–3.735)

0.404