El-Zem R, Bondy M, Wrensch M. Epidemiology of brain tumors. In: Osman FA, editor. Brain Tumors. New Jersey: Humana Press; 2005. p. 3–18.
Chapter
Google Scholar
WHO 2016, Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Ellison DW, Figarella-Branger D, Perry A, Reifenberger G, Deimiling AV. The 2016 WHO classification of tumors of the central nervous system, Revised 4th edition. Lyon: International Agency for Research on Cancer (IARC); 2016.
Google Scholar
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumors of the central nervous system, fourth Edi., vol. 114, no. 2. Lyon: International Agency for Research on Cancer (IARC). p. 2007.
Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, a Boop F, Lu C, Kandoth C, Ding L, Lee R, Huether R, Chen X, Hedlund E, Nagahawatte P, Rusch M, Boggs J, Cheng J, Becksfort J, Ma J, Song G, Li Y, Wei L, Wang J, Shurtleff S, Easton J, Zhao D, Fulton RS, Fulton LL, Dooling DJ, Vadodaria B, Mulder HL, Tang C, Ochoa K, Mullighan CG, Gajjar A, Kriwacki R, Sheer D, Gilbertson RJ, Mardis ER, Wilson RK, Downing JR, Baker SJ, Ellison DW. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 2013; 45(6): 602–612.
Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Shumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD. Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. PNAS. 2013;110(20):8188–93.
Article
CAS
Google Scholar
Jones DTW, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DAK, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott P, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet. 2013;45(8):927–32.
Article
CAS
Google Scholar
Tatevossian RG, Tatevossian BRG, Tang B, Dalton J, Forshew T, Lawson AR, Ma J, Neale G, Shurtleff SA, Bailey S, Gajjar A, Baker SJ, Sheer D, Ellison DW. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathol. 2010;120(6):731–43.
Article
Google Scholar
Gerges N, Fontebasso AM, Albrecht S, Faury D, Jabado N. Pediatric high-grade astrocytomas : a distinct neuro-oncological paradigm. Genome Med. 2013;5(7):66.
Article
CAS
Google Scholar
Gierke M, Sperveslage J, Schwab D, Beschorner R, Ebinger M, Schuhmann MU, Schittenhelm J. Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549–BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification. J Cancer Res Clin Oncol. 2016;142(1):89–100.
Article
CAS
Google Scholar
Antonelli M, Badiali M, Moi L, Buttarelli FR, Baldi C, Massimino M, Sanson M, Giangaspero F. KIAA1549-BRAF Fusion Gene in Pediatric Brain Tumors of Various Histogenesis. Pediatr Blood Cancer. 2015;62(4):724–7.
Article
CAS
Google Scholar
Sievert AJ, Lang SS, Boucher KL, Madsen PJ, Slaunwhite E, Choudhari N, Kellet M, Storm PB, Resnick AC. Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas. PNAS. 2013;110(15):5957–62.
Article
CAS
Google Scholar
Hawkins C, Walker E, Mohamad N, Zang C, Jacob K, Shirinian M, Alon N, Kahn D, Fried I, Scheinemann K, Tsangaris E, Dirks P, Tressler R, Bouffet E, Jabado N, Tabori U. KIAA1549-BRAF fusion predicts better clinical outcome in paediatric low-grade astrocytoma. Clin Cancer Res. 2011;17(14):4790–8.
Article
CAS
Google Scholar
Horbinski C, Nikiforova MN, hagenkord JM, Hamilton RL, Pollack IF. Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas. Neuro-Oncologia. 2012;14(6):777–89.
Article
CAS
Google Scholar
Jones DWT, Kocialkowski S, Liu L, Pearson DM, Backlund LM, Ichimura K, Collins VP. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytoma. Cancer Res. 2008;68(21):8673–7.
Article
CAS
Google Scholar
Schindler G, Capper D, Meyer J, Janzarik W, Omran H, Herold-Mende C, Schmieder K, Wesseling P, Mawrin C, Hasselblatt M, Louis DN, Korshunov A, Pfister SM, Hartmann C, Paulus W, Reifenberger G, Von Deimling A. Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma. Acta Neuropathol. 2011;121(3):397–405.
Mistry M, Zhukova N, Merico D, Rakopoulos P, Krishnatry R, Shago M, Stavropoulos J, Alon N, Pole JD, Ray PN, Navickiene V, Mangerel J, Remke M, Buczkowicz P, Vamaswamy V, Guerreiro Stucklin A, Li M, Young EJ, Zhang C, Castelo-Branco P, Bakry D, Laughlin S, Shlien A, Chan J, Ligon KL, Rutka JT, Dirks PD, Taylor MD, Greenberg M, Malkin D, Huang A, Bouffet E, Hawkins CE, Tabori U. BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma. J Clin Oncol. 2015;33(9):1015–22.
Korshunov A, Ryzhova M, Hovestadt V, Bender S, Sturm D, Capper D, Meyer J, Schrimpf D, Kool M, Northcott P, Zheludkova O, Milde T, Witt O, Kulozik AE, Reifenberger G, Jabado N, Perry A, Lichter P, von Deimling A, Pfister SM, Jones DWT. Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers. Acta Neuropathol. 2015;129(5):669–78.
Article
CAS
Google Scholar
Raabe EH, Lim KS, Kim JM, Meeker A, Mao XG, Nikkhah G, Maciaczyk J, Kahlert U, Jain D, Bar E, Cohen KJ. Eberhart CG. BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model. Clin Cancer Res. 2011;17(11):3590–9.
Article
CAS
Google Scholar
Beillard E, Pallisgaard N, Bi W, van der Velden VHJ, Dee R, van der Schoot CE, Delabesse E, Macintyre E, Gottardi E, Saglio G, Watzinger F, Lion T, van Dongen JJM, Hokland P, Gabert J. Evaluation of candidate control genes for leukemic patients using ‘real-time’ quantitative reverse-transcriptase polimerase chain reaction (RQ-PCR) – a European against Cancer program. Leukemia. 2003;17:2474–86.
Article
CAS
Google Scholar
Roy DM, Walsh LA, Desrichard A, Huse JT, Wu W, Gao J, Bose P, Lee W, Chan TA. Integrated genomics for pinpointing survival loci within arm-level somatic copy number alterations. Cancer Cell. 2016;29(5):737–50.
Article
CAS
Google Scholar
Huillard E, Hashizume R, Phillips JJ, Griveau A, Ihrie RA, Aoki Y, Nicolaides T, Perry A, Waldman T, McMahon M, Weiss WA, Petritsch C, James CD, Rowitch DH. Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. PNAS. 2012;109(22):8710–5.
Mavrakis KJ, ER MD 3rd, Mr S, Billy E, Hoffman GR, deWeck A, Ruddy DA, Venkatesan K, Yu J, McAllister G, Stump M, de Beaumont R, Ho S, Yue Y, Liu Y-NY, Yang G, Lin F, Gao H, Kipp DR, Zhao S, Mcnamara JT, Sprague ER, Zheng B, Tallarico J, Mickanin C, Lees E, Pagliarini R, Keen K, Schmelzle T, Hofmann F, Stegmeier F, Sellers WR. Disordered methionie metabolism in MTAP/CDKN2A-deleted cancers to depence of PRMT5. Science. 2016;351(6278):1208–13.
Marjon K, Cameron MJ, Quang P, Clasquin MF, Mandley E, Kunni K, McVay M, Choe S, Kemytsky A, Gross S, Konteatis Z, Murtie J, Blake ML, Travins J, Dorsch M, Biller SA, Marks KM. MTAP deletions in Cancer create vulnerability to targeting of MAT2A/PRMT5/RIOK1 Axis. Cell Rep. 2016;15(3):574–87.
Harrison CJ, Johansson B. Acute Lymphoblastic Leukemia. In: Heim S, Mitelman F, editors. Cancer Cytogenetics. 4th ed: Willey-Blackwell; 2015. p. 233–96.
Alexiou GA. High-grade gliomas in survivors of childhood acute lymphoblastic leukaemia. Childs Nerv Syst. 2009;25(7):779 author reply 781-2.
Article
Google Scholar
Alexiou GA, Moschovi M, Georgoulis G, Neroutsou R, Stefanaki K, Sfakianos G, Prodromou N. Anaplastic oligodendrogliomas after treatment of acute lymphoblastic leukemia in children: report of 2 cases. J Neurosurg Pediatr. 2010;5(2):179–83.
Article
Google Scholar