Levin VA, Sheline GE, Cutin PH: Neoplasms of the central nervous system. Cancer Principles and Practice of Oncology. Edited by: De Vita VTJ, Hellman S and Rosenberg SA. 1993, Philadelphia, J.B. Lippincott Company, 1679-1737. 4th
Google Scholar
Posner JB: Neurologic complications of cancer. 1995, Philadelphia, F.A. Davis Company
Google Scholar
Posner JB, Chernik NL: Intracranial metastases from systemic cancer. Adv Neurol. 1978, 19: 579-591.
CAS
PubMed
Google Scholar
Sawaya R, Bindal RK: Metastatic brain tumors. Brain tumors. Edited by: Kaye AH and Laws JER. 1995, Edinburgh, Churchill Livingstone, 923-946.
Google Scholar
Arbit E, Wronski M: Clinical decision making in brain metastases. Neurosurg Clinics North Am. 1996, 7: 447-457.
CAS
Google Scholar
Patchell RA: The treatment of brain metastases. Cancer Invest. 1996, 14: 169-177.
Article
CAS
PubMed
Google Scholar
Ayash LJ, Elias A, Schwartz G, Wheeler C, Ibrahim J, Teichler BA, Reich E, Warren D, Lynch C, Richardson P, Snipper L, Frei E, Antman K: Double dose of intensive chemotherapy with autologous stem cell support for metastatic breast cancer: no improvement in progression-free survival by the sequence of high-dose melphalan followed by cyclophosphamide, thiotepa, and caboplatin. J Clin Oncol. 1996, 14: 2984-2992.
CAS
PubMed
Google Scholar
Thorgeirsson UP, Lindsay CK, Cottam DW, Gomez DE: Tumor invasion, proteolysis, and angiogenesis. J Neuro-Oncol. 1994, 18: 89-103. 10.1007/BF01050415.
Article
CAS
Google Scholar
Plow EF, Herren T, Redlitz A, Miles LA, Hoover-Plow JL: The cell biology of the plasminogen system. FASEB J. 1995, 9: 939-945.
CAS
PubMed
Google Scholar
Vassalli JD, Sappino AP, Belin D: The plasminogen activator/plasmin system. J Clin Invest. 1991, 88: 1067-1072.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sober AJ, Koh HK, Tran NLT, Washington CBJ: Melanoma and other skin cancers. Harrison's Principles of Internal Medicine. Edited by: Fauci AS, Braunwald E, Isselbacher JJ, D. WJ, Martin JB, Kasper DL, Hauser SL and Longo DL. 1998, New York, McGraw-Hill, 543-549. 14th
Google Scholar
Stins MF, Gilles F, Kim KS: Selective expression of adhesion molecules on human brain microvascular endothelial cells. J Neuroimmunol. 1997, 76: 81-90. 10.1016/S0165-5728(97)00036-2.
Article
CAS
PubMed
Google Scholar
Persidsky Y, Stins M, Way D, Witte MH, Weinand M, Kim KS, Bock P, Gendelman HE, Fiala M: A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis. J Immunol. 1997, 158: 3499-3510.
CAS
PubMed
Google Scholar
Ploplis VA, Carmeliet P, Vazirzadeh S, Van Vlaenderen I, Moons L, Plow EF, Collen D: Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice. Circulation. 1995, 92: 2585-2593.
Article
CAS
PubMed
Google Scholar
Schackert G, Fidler IJ: Development of in vivo models for studies of brain metastasis. Int J Cancer. 1988, 41: 589-594.
Article
CAS
PubMed
Google Scholar
Hughes WL, Commerford SL, Gitlin D, Krueger RC, Schultze B, Shah V, Reilly P: Deoxyribonucleic acid metabolism in vivo: cell proliferation and death as measured by incorporation and elimination of iododeoxyuridine. Fed Proc. 1964, 23: 640-648.
CAS
PubMed
Google Scholar
Schackert G, Price JE, Bucana CD, Fidler IJ: Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice. Int J Cancer. 1989, 44: 892-897.
Article
CAS
PubMed
Google Scholar
Sawaya R, Mandybur T, Ormsby I, Tew JMJ: Antifibrinolytic therapy of experimentally grown malignant brain tumors. J Neurosurg. 1989, 64: 263-268.
Article
Google Scholar
Brockway WJ, Castellino FJ: The mechanism of the inhibition of plasmin activity by e-aminocaproic acid. The Journal of Biological Chemistry. 1971, 246: 4641-4647.
CAS
Google Scholar
Stins MF, Prasadarao NV, Zhou J, Arditi M, Kim KS: Bovine brain microvascular endothelial cells transfected with SV40-large T antigen: development of an immortalized cell line to study pathophysiology of CNS disease. In Vitro Cell Dev Biol Anim. 1997, 33: 243-247.
Article
CAS
PubMed
Google Scholar
Butler WB, Kirkland WL, Jorgensen TL: Induction of plasminogen activator by estrogen in a human breast cancer cell line (MCF-7). Biochemical & Biophysical Research Communications. 1979, 90: 1328-1334.
Article
CAS
Google Scholar
Duffy MJ, Duggan C, Maguire T, Mulcahy K, Elvin P, McDermontt E, Fennelly JJ, O'Higgins N: Urokinase plasminogen activator as a predictor of aggressive disease in breast cancer. Enzyme & Protein. 1996, 49: 85-93.
CAS
Google Scholar
Ronne E, Hoyer-Hansen G, Brunner N, Pedersen H, Rank F, Osborne CK, Clark GM, Dano K, Grondahl-Hansen J: Urokinase receptor in breast cancer tissue extracts. Enzyme-linked immunosorbent assay with a combination of mono- and polyclonal antibodies. Breast Cancer Res Treatm. 1995, 33: 199-207. 10.1007/BF00665944.
Article
CAS
Google Scholar
Schmitt M, Janicke F, Moniwa N, Chucholowski N, Pache L, Graeff H: Tumor-associated urokinase-type plasminogen activator: biological and clinical significance. Biol Chem Hoppe-Seyler. 1992, 373: 611-622.
Article
CAS
PubMed
Google Scholar
Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmback K, Drew AF, Flick MJ, Witte DP, Dano K, Degen JL: Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice. Oncogene. 1998, 16: 3097-3104. 10.1038/sj.onc.1201869.
Article
CAS
PubMed
Google Scholar
Praus M, Wauterickx K, Collen D, Gerard RD: Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors. Gene Ther. 1999, 6: 227-236. 10.1038/sj.gt.3300802.
Article
CAS
PubMed
Google Scholar
Praus M, Collen D, Gerard RD: Both u-PA inhibition and vitronectin binding by plasminogen activator inhibitor 1 regulate HT1080 fibrosarcoma cell metastasis. Int J Cancer. 2002, 102: 584-591. 10.1002/ijc.10767.
Article
CAS
PubMed
Google Scholar
Szende B, Okada Y, Tsuda Y, Horvath A, Bokonyi G, Okamoto S, Wanaka K, Keri G: A novel plasmin-inhibitor inhibits the growth of human tumor xenografts and decreases metastasis number. In Vivo. 2002, 16: 281-286.
CAS
PubMed
Google Scholar
Rabbani SA, Harakidas P, Davidson DJ, Henkin J, Mazar AP: Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA). International Journal of Cancer. 1995, 63: 840-845.
Article
CAS
PubMed
Google Scholar
Xing RH, Rabbani SA: Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis. International Journal of Cancer. 1996, 67: 423-429. 10.1002/(SICI)1097-0215(19960729)67:3<423::AID-IJC18>3.0.CO;2-8.
Article
CAS
PubMed
Google Scholar
Stetler-Stevenson WG: Progelatinase A activation during tumor cell invasion. Invasion Metastasis. 1994, 14: 259-268.
CAS
PubMed
Google Scholar
Maguire T, Chin D, Souta D, Duffy MJ: Low levels of urokinase plasminogen activator components in basal cell carcinoma of the skin. International Journal of Cancer. 2000, 85: 457-459. 10.1002/(SICI)1097-0215(20000215)85:4<457::AID-IJC2>3.0.CO;2-6.
Article
CAS
PubMed
Google Scholar
Stahl A, Mueller BM: Melanoma cell migration on vitronectin: regulation by components of the plasminogen activation system. International Journal of Cancer. 1997, 71: 116-122. 10.1002/(SICI)1097-0215(19970328)71:1<116::AID-IJC19>3.0.CO;2-G.
Article
CAS
PubMed
Google Scholar
Ignar DM, Andrews JL, Witherspoon SM, Leray JD, Clay WC, Kilpatrick K, Onori J, Kost T, Emerson DL: Inhibition of establishment of primary and micrometastatic tumors by a urokinase plasminogen activator receptor antagonist. Clin Exp Metastasis. 1998, 16: 9-20. 10.1023/A:1006503816792.
Article
CAS
PubMed
Google Scholar
Ma D, Gerard RD, Li XY, Alizadeh H, Niederkorn JY: Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model. Blood. 1997, 90: 2738-2746.
CAS
PubMed
Google Scholar
Gundersen D, Tran-Thang C, Sordat B, Mourali F, Ruegg C: Plasmin-induced proteolysis of tenascin-C: modulation by T lymphocyte-derived urokinase-type plasminogen activator and effect on T lymphocyte adhesion, activation, and cell clustering. J Immunol. 1997, 158: 1051-1060.
CAS
PubMed
Google Scholar
Waltz DA, Natkin LR, Fujita RM, Wei Y, Chapman HA: Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin. J Clin Invest. 1997, 100: 58-67.
Article
CAS
PubMed
PubMed Central
Google Scholar
Barilla ML, Carsons SE: Fibronectin fragments and their role in inflammatory arthritis. Semin Arthritis Rheum. 2000, 29: 252-265. 10.1016/S0049-0172(00)80012-8.
Article
CAS
PubMed
Google Scholar
Chen ZL, Strickland S: Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell. 1997, 91: 917-925. 10.1016/S0092-8674(00)80483-3.
Article
CAS
PubMed
Google Scholar
Silletti S, Mei F, Sheppard D, Montgomery AM: Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitment. J Cell Biol. 2000, 149: 1485-1502. 10.1083/jcb.149.7.1485.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cairns RA, Khokha R, Hill RP: Molecular mechanisms of tumor invasion and metastasis: an integrated view. Curr Mol Med. 2003, 3: 659-671. 10.2174/1566524033479447.
Article
CAS
PubMed
Google Scholar
Arnold SM, Young AB, Munn RK, Patchell RA, Nanayakkara N, Markesbery WR: Expression of p53, bcl-2, E-cadherin, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinases-1 in paired primary tumors and brain metastasis. Clin Cancer Res. 1999, 5: 4028-4033.
CAS
PubMed
Google Scholar
Shintani Y, Higashiyama S, Ohta M, Hirabayashi H, Yamamoto S, Yoshimasu T, Matsuda H, Matsuura N: Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis. Cancer Res. 2004, 64: 4190-4196. 10.1158/0008-5472.CAN-03-3235.
Article
CAS
PubMed
Google Scholar
Gijbels K, Galardy RE, Steinman L: Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. Journal of Clinical Investigation. 1994, 94: 2177-2182.
Article
CAS
PubMed
PubMed Central
Google Scholar