Briasoulis E, Pavlidis N: Cancer of Unknown Primary Origin. Oncologist. 1997, 2: 142-152.
PubMed
Google Scholar
Pavlidis N, Briasoulis E, Hainsworth J, Greco FA: Diagnostic and therapeutic management of cancer of an unknown primary. Eur J Cancer. 2003, 39: 1990-2005. 10.1016/S0959-8049(03)00547-1.
Article
CAS
PubMed
Google Scholar
van de Wouw AJ, Jansen RL, Speel EJ, Hillen HF: The unknown biology of the unknown primary tumour: a literature review. Ann Oncol. 2003, 14: 191-196. 10.1093/annonc/mdg068.
Article
CAS
PubMed
Google Scholar
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989, 246: 1306-1309.
Article
CAS
PubMed
Google Scholar
Ferrara N: VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002, 2: 795-803. 10.1038/nrc909.
Article
CAS
PubMed
Google Scholar
Iruela-Arispe ML, Luque A, Lee N: Thrombospondin modules and angiogenesis. Int J Biochem Cell Biol. 2004, 36: 1070-1078. 10.1016/j.biocel.2004.01.025.
Article
CAS
PubMed
Google Scholar
Culine S, Kramar A, Saghatchian M, Bugat R, Lesimple T, Lortholary A, Merrouche Y, Laplanche A, Fizazi K: Development and validation of a prognostic model to predict the length of survival in patients with carcinomas of an unknown primary site. J Clin Oncol. 2002, 20: 4679-4683. 10.1200/JCO.2002.04.019.
Article
PubMed
Google Scholar
van de Wouw AJ, Jansen RL, Griffioen AW, Hillen HF: Clinical and immunohistochemical analysis of patients with unknown primary tumour. A search for prognostic factors in UPT. Anticancer Res. 2004, 24: 297-301.
PubMed
Google Scholar
Ferrara N, Hillan KJ, Gerber HP, Novotny W: Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov. 2004, 3: 391-400. 10.1038/nrd1381.
Article
CAS
PubMed
Google Scholar
Briasoulis E, Tsokos M, Fountzilas G, Bafaloukos D, Kosmidis P, Samantas E, Skarlos D, Nicolaides C, Pavlidis N: Bcl2 and p53 protein expression in metastatic carcinoma of unknown primary origin: biological and clinical implications. A Hellenic Co-operative Oncology Group study. Anticancer Res. 1998, 18: 1907-1914.
CAS
PubMed
Google Scholar
Pavlidis N, Briassoulis E, Bai M, Fountzilas G, Agnantis N: Overexpression of C-myc, Ras and C-erbB-2 oncoproteins in carcinoma of unknown primary origin. Anticancer Res. 1995, 15: 2563-2567.
CAS
PubMed
Google Scholar
Adams J, Carder PJ, Downey S, Forbes MA, MacLennan K, Allgar V, Kaufman S, Hallam S, Bicknell R, Walker JJ, Cairnduff F, Selby PJ, Perren TJ, Lansdown M, Banks RE: Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen. Cancer Res. 2000, 60: 2898-2905.
CAS
PubMed
Google Scholar
Mattern J, Koomagi R, Volm M: Association of vascular endothelial growth factor expression with intratumoral microvessel density and tumour cell proliferation in human epidermoid lung carcinoma. Br J Cancer. 1996, 73: 931-934.
Article
CAS
PubMed
PubMed Central
Google Scholar
Albo D, Rothman VL, Roberts DD, Tuszynski GP: Tumour cell thrombospondin-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor. Br J Cancer. 2000, 83: 298-306. 10.1054/bjoc.2000.1268.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kodama J, Hashimoto I, Seki N, Hongo A, Yoshinouchi M, Okuda H, Kudo T: Thrombospondin-1 and -2 messenger RNA expression in invasive cervical cancer: correlation with angiogenesis and prognosis. Clin Cancer Res. 2001, 7: 2826-2831.
CAS
PubMed
Google Scholar
Grossfeld GD, Ginsberg DA, Stein JP, Bochner BH, Esrig D, Groshen S, Dunn M, Nichols PW, Taylor CR, Skinner DG, Cote RJ: Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression. J Natl Cancer Inst. 1997, 89: 219-227. 10.1093/jnci/89.3.219.
Article
CAS
PubMed
Google Scholar
Levi F, Te VC, Erler G, Randimbison L, La Vecchia C: Epidemiology of unknown primary tumours. Eur J Cancer. 2002, 38: 1810-1812. 10.1016/S0959-8049(02)00135-1.
Article
CAS
PubMed
Google Scholar
van de Wouw AJ, Janssen-Heijnen ML, Coebergh JW, Hillen HF: Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992. Eur J Cancer. 2002, 38: 409-413. 10.1016/S0959-8049(01)00378-1.
Article
CAS
PubMed
Google Scholar
Hess KR, Abbruzzese MC, Lenzi R, Raber MN, Abbruzzese JL: Classification and regression tree analysis of 1000 consecutive patients with unknown primary carcinoma. Clin Cancer Res. 1999, 5: 3403-3410.
CAS
PubMed
Google Scholar
Greco FA, Vaughn WK, Hainsworth JD: Advanced poorly differentiated carcinoma of unknown primary site: recognition of a treatable syndrome. Ann Intern Med. 1986, 104: 547-553.
Article
CAS
PubMed
Google Scholar
Pavlidis N, Kosmidis P, Skarlos D, Briassoulis E, Beer M, Theoharis D, Bafaloukos D, Maraveyas A, Fountzilas G: Subsets of tumors responsive to cisplatin or carboplatin combinations in patients with carcinoma of unknown primary site. A Hellenic Cooperative Oncology Group Study. Ann Oncol. 1992, 3: 631-634.
CAS
PubMed
Google Scholar
Strnad CM, Grosh WW, Baxter J, Burnett LS, Jones HWIII, Greco FA, Hainsworth JD: Peritoneal carcinomatosis of unknown primary site in women. A distinctive subset of adenocarcinoma. Ann Intern Med. 1989, 111: 213-217.
Article
CAS
PubMed
Google Scholar
Blanchard DK, Farley DR: Retrospective Study of Women Presenting with Axillary Metastases from Occult Breast Carcinoma. World J Surg. 2004, 28: 535-539. 10.1007/s00268-004-7290-y.
Article
PubMed
Google Scholar
Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P: Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. J Clin Oncol. 1994, 12: 1272-1280.
CAS
PubMed
Google Scholar
Hillen HF, Hak LE, Joosten-Achjanie SR, Arends JW: Microvessel density in unknown primary tumors. Int J Cancer. 1997, 74: 81-85.
Article
CAS
PubMed
Google Scholar