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Table 4 Immunohistochemical expression of CD34 (MVD). VEGF, and TSP-1 and correlations.

From: Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1

Variable

MVD (counts)

 

VEGF (%)

 

TSP-1 (%)

 
 

Median CD 34

P value

Low (<4)

High (≥4)

P value

Low (<2)

High (≥2)

P value

Age

 

ns

  

ns

  

ns

< 65

62

 

20

80

 

35

27

 

> 65

58

 

15

85

 

22

16

 

Tumor differentiation

 

ns

  

ns

  

ns

Moderate and well

55

 

3

28

 

12

20

 

Poorly and undifferentiated

59

 

14

55

 

32

36

 

Clinical subgroups

 

0.034

  

ns

  

ns

More favorable

46

 

6

46

 

28

23

 

Unfavorable

70

 

11

37

 

22

27

 

Treatment outcome

 

ns

  

ns

  

ns

Objective response

58

 

11

39

 

22

28

 

No response

59

 

4

46

 

25

25

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