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Table 4 Immunohistochemical expression of CD34 (MVD). VEGF, and TSP-1 and correlations.

From: Angiogenesis in cancer of unknown primary: clinicopathological study of CD34, VEGF and TSP-1

Variable MVD (counts)   VEGF (%)   TSP-1 (%)  
  Median CD 34 P value Low (<4) High (≥4) P value Low (<2) High (≥2) P value
Age   ns    ns    ns
< 65 62   20 80   35 27  
> 65 58   15 85   22 16  
Tumor differentiation   ns    ns    ns
Moderate and well 55   3 28   12 20  
Poorly and undifferentiated 59   14 55   32 36  
Clinical subgroups   0.034    ns    ns
More favorable 46   6 46   28 23  
Unfavorable 70   11 37   22 27  
Treatment outcome   ns    ns    ns
Objective response 58   11 39   22 28  
No response 59   4 46   25 25