Fritz G, Just I, Kaina B: Rho GTPases are over-expressed in human tumors. Int J Cancer. 1999, 81 (5): 682-687. 10.1002/(SICI)1097-0215(19990531)81:5<682::AID-IJC2>3.0.CO;2-B.
Article
CAS
PubMed
Google Scholar
Bellizzi A, Mangia A, Chiriatti A, Petroni S, Quaranta M, Schittulli F, Malfettone A, Cardone RA, Paradiso A, Reshkin SJ: RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease. Int J Mol Med. 2008, 22 (1): 25-31.
CAS
PubMed
Google Scholar
Li XR, Ji F, Ouyang J, Wu W, Qian LY, Yang KY: Overexpression of RhoA is associated with poor prognosis in hepatocellular carcinoma. Eur J Surg Oncol. 2006, 32 (10): 1130-1134. 10.1016/j.ejso.2006.05.012.
Article
CAS
PubMed
Google Scholar
Gomez Del Pulgar T, Benitah SA, Valeron PF, Espina C, Lacal JC: Rho GTPase expression in tumourigenesis: evidence for a significant link. Bioessays. 2005, 27 (6): 602-613. 10.1002/bies.20238.
Article
PubMed
Google Scholar
Nobes CD, Hall A: Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell. 1995, 81 (1): 53-62. 10.1016/0092-8674(95)90370-4.
Article
CAS
PubMed
Google Scholar
Rottner K, Hall A, Small JV: Interplay between Rac and Rho in the control of substrate contact dynamics. Curr Biol. 1999, 9 (12): 640-648. 10.1016/S0960-9822(99)80286-3.
Article
CAS
PubMed
Google Scholar
Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG: Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol. 1999, 147 (5): 1009-1022. 10.1083/jcb.147.5.1009.
Article
CAS
PubMed
PubMed Central
Google Scholar
Haataja L, Groffen J, Heisterkamp N: Characterization of RAC3, a novel member of the Rho family. J Biol Chem. 1997, 272 (33): 20384-20388. 10.1074/jbc.272.33.20384.
Article
CAS
PubMed
Google Scholar
Chou MM, Blenis J: The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1. Cell. 1996, 85 (4): 573-583. 10.1016/S0092-8674(00)81257-X.
Article
CAS
PubMed
Google Scholar
Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF: Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells. Breast Cancer Res. 2005, 7 (6): R965-974. 10.1186/bcr1329.
Article
CAS
PubMed
PubMed Central
Google Scholar
Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ: Molecular basis for Rac1 recognition by guanine nucleotide exchange factors. Nat Struct Biol. 2001, 8 (12): 1037-1041. 10.1038/nsb719.
Article
CAS
PubMed
Google Scholar
Cho YJ, Zhang B, Kaartinen V, Haataja L, de Curtis I, Groffen J, Heisterkamp N: Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia. Mol Cell Biol. 2005, 25 (13): 5777-5785. 10.1128/MCB.25.13.5777-5785.2005.
Article
CAS
PubMed
PubMed Central
Google Scholar
Leung K, Nagy A, Gonzalez-Gomez I, Groffen J, Heisterkamp N, Kaartinen V: Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions. Cells, tissues, organs. 2003, 175 (2): 72-83. 10.1159/000073751.
Article
CAS
PubMed
Google Scholar
Hwang SL, Chang JH, Cheng TS, Sy WD, Lieu AS, Lin CL, Lee KS, Howng SL, Hong YR: Expression of Rac3 in human brain tumors. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia. 2005, 12 (5): 571-574. 10.1016/j.jocn.2004.08.013.
Article
CAS
Google Scholar
Tuschl T: Expanding small RNA interference. Nat Biotechnol. 2002, 20 ((5): 446-448.
Article
CAS
PubMed
Google Scholar
Pan Y, Bi F, Liu N, Xue Y, Yao X, Zheng Y, Fan D: Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun. 2004, 315 (3): 686-691. 10.1016/j.bbrc.2004.01.108.
Article
CAS
PubMed
Google Scholar
Cominetti MR, Martin AC, Ribeiro JU, Djaafri I, Fauvel-Lafeve F, Crepin M, Selistre-de-Araujo HS: Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions. Biochimie. 2009, 91 (8): 1045-1052. 10.1016/j.biochi.2009.05.012.
Article
CAS
PubMed
Google Scholar
Monnet E, Sizaret P, Arbeille B, Fauvel-Lafeve F: Different role of platelet glycoprotein GP Ia/IIa in platelet contact and activation induced by type I and type III collagens. Thromb Res. 2000, 98 (5): 423-433. 10.1016/S0049-3848(00)00199-7.
Article
CAS
PubMed
Google Scholar
Mekrache M, Legendre P, Kieffer N, Baruch D: Activation of integrin alphaIIbbeta3 expressed in Chinese hamster ovary cells is required for interaction with solid-phase von Willebrand factor. Br J Haematol. 2002, 119 (4): 1024-1032. 10.1046/j.1365-2141.2002.03960.x.
Article
CAS
PubMed
Google Scholar
Garamszegi N, Garamszegi SP, Shehadeh LA, Scully SP: Extracellular matrix-induced gene expression in human breast cancer cells. Mol Cancer Res. 2009, 7 (3): 319-329. 10.1158/1541-7786.MCR-08-0227.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zohrabian VM, Nandu H, Gulati N, Khitrov G, Zhao C, Mohan A, Demattia J, Braun A, Das K, Murali R, et al: Gene expression profiling of metastatic brain cancer. Oncol Rep. 2007, 18 (2): 321-328.
CAS
PubMed
Google Scholar
Zhang S, Zhang D, Sun B: Vasculogenic mimicry: current status and future prospects. Cancer Lett. 2007, 254 (2): 157-164. 10.1016/j.canlet.2006.12.036.
Article
CAS
PubMed
Google Scholar
Pille JY, Denoyelle C, Varet J, Bertrand JR, Soria J, Opolon P, Lu H, Pritchard LL, Vannier JP, Malvy C, et al: Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo. Mol Ther. 2005, 11 (2): 267-274. 10.1016/j.ymthe.2004.08.029.
Article
CAS
PubMed
Google Scholar
Mira JP, Benard V, Groffen J, Sanders LC, Knaus UG: Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway. Proc Natl Acad Sci U S A. 2000, 97 (1): 185-189. 10.1073/pnas.97.1.185.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chan AY, Coniglio SJ, Chuang YY, Michaelson D, Knaus UG, Philips MR, Symons M: Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion. Oncogene. 2005, 24 (53): 7821-7829. 10.1038/sj.onc.1208909.
Article
CAS
PubMed
Google Scholar
Hajdo-Milasinovic A, Ellenbroek SI, van Es S, van der Vaart B, Collard JG: Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells. J Cell Sci. 2007, 120 (Pt 4): 555-566.
Article
CAS
PubMed
Google Scholar
Joyce PL, Cox AD: Rac1 and Rac3 are targets for geranylgeranyltransferase I inhibitor-mediated inhibition of signaling, transformation, and membrane ruffling. Cancer Res. 2003, 63 (22): 7959-7967.
CAS
PubMed
Google Scholar
Rathinam R, Alahari SK: Important role of integrins in the cancer biology. Cancer Metastasis Rev. 2010, 29 (1): 223-237. 10.1007/s10555-010-9211-x.
Article
CAS
PubMed
Google Scholar
Pecheur I, Peyruchaud O, Serre CM, Guglielmi J, Voland C, Bourre F, Margue C, Cohen-Solal M, Buffet A, Kieffer N, et al: Integrin alpha(v)beta3 expression confers on tumor cells a greater propensity to metastasize to bone. FASEB J. 2002, 16 (10): 1266-1268.
CAS
PubMed
Google Scholar
Le Clainche C, Carlier MF: Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev. 2008, 88 (2): 489-513. 10.1152/physrev.00021.2007.
Article
CAS
PubMed
Google Scholar
Sheetz MP, Felsenfeld DP, Galbraith CG: Cell migration: regulation of force on extracellular-matrix-integrin complexes. Trends Cell Biol. 1998, 8 (2): 51-54.
Article
CAS
PubMed
Google Scholar
Folberg R, Maniotis AJ: Vasculogenic mimicry. APMIS. 2004, 112 (7–8): 508-525.
Article
PubMed
Google Scholar
Sun B, Qie S, Zhang S, Sun T, Zhao X, Gao S, Ni C, Wang X, Liu Y, Zhang L: Role and mechanism of vasculogenic mimicry in gastrointestinal stromal tumors. Hum Pathol. 2008, 39 (3): 444-451. 10.1016/j.humpath.2007.07.018.
Article
CAS
PubMed
Google Scholar
Lee FS, Hagler J, Chen ZJ, Maniatis T: Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell. 1997, 88 (2): 213-222. 10.1016/S0092-8674(00)81842-5.
Article
CAS
PubMed
Google Scholar
Karin M, Ben-Neriah Y: Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol. 2000, 18: 621-663. 10.1146/annurev.immunol.18.1.621.
Article
CAS
PubMed
Google Scholar
Ling H, Yang H, Tan SH, Chui WK, Chew EH: 6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion by reducing matrix metalloproteinase-9 expression via blockade of nuclear factor-kappaB activation. Br J Pharmacol. 2010, 161 (8): 1763-1777. 10.1111/j.1476-5381.2010.00991.x.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vayalil PK, Katiyar SK: Treatment of epigallocatechin-3-gallate inhibits matrix metalloproteinases-2 and −9 via inhibition of activation of mitogen-activated protein kinases, c-jun and NF-kappaB in human prostate carcinoma DU-145 cells. Prostate. 2004, 59 (1): 33-42. 10.1002/pros.10352.
Article
CAS
PubMed
Google Scholar
Gupta S, Su H, Bi R, Agrawal S, Gollapudi S: Life and death of lymphocytes: a role in immunesenescence. Immunity & ageing: I & A. 2005, 2: 12-10.1186/1742-4933-2-12.
Article
Google Scholar
Kishimoto T: The biology of interleukin-6. Blood. 1989, 74 (1): 1-10.
CAS
PubMed
Google Scholar
Moore KW, de Waal MR, Coffman RL, O'Garra A: Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol. 2001, 19: 683-765. 10.1146/annurev.immunol.19.1.683.
Article
CAS
PubMed
Google Scholar
Yssel H, De Waal MR, Roncarolo MG, Abrams JS, Lahesmaa R, Spits H, de Vries JE: IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells. J Immunol. 1992, 149 (7): 2378-2384.
CAS
PubMed
Google Scholar
Kozlowski L, Zakrzewska I, Tokajuk P, Wojtukiewicz MZ: Concentration of interleukin-6 (IL-6), interleukin-8 (IL-8) and interleukin-10 (IL-10) in blood serum of breast cancer patients. Rocz Akad Med Bialymst. 2003, 48: 82-84.
CAS
PubMed
Google Scholar
Youngs SJ, Ali SA, Taub DD, Rees RC: Chemokines induce migrational responses in human breast carcinoma cell lines. Int J Cancer. 1997, 71 (2): 257-266. 10.1002/(SICI)1097-0215(19970410)71:2<257::AID-IJC22>3.0.CO;2-D.
Article
CAS
PubMed
Google Scholar
Barnes PJ, Karin M: Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997, 336 (15): 1066-1071. 10.1056/NEJM199704103361506.
Article
CAS
PubMed
Google Scholar
Amiri KI, Richmond A: Fine tuning the transcriptional regulation of the CXCL1 chemokine. Prog Nucleic Acid Res Mol Biol. 2003, 74: 1-36.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C: IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res. 2011, 71 (15): 5296-5306. 10.1158/0008-5472.CAN-11-0156.
Article
CAS
PubMed
PubMed Central
Google Scholar
Patel S, Vetale S, Teli P, Mistry R, Chiplunkar S: IL-10 production in non-small cell lung carcinoma patients is regulated by ERK, P38 and COX-2. J Cell Mol Med. 2011
Google Scholar
Takenawa T, Miki H: WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement. J Cell Sci. 2001, 114 (Pt 10): 1801-1809.
CAS
PubMed
Google Scholar