Chan CW, Housseau F: The 'kiss of death' by dendritic cells to cancer cells. Cell Death Differ. 2008, 15: 58-69. 10.1038/sj.cdd.4402235.
Article
CAS
PubMed
Google Scholar
van Mierlo GJ, Boonman ZF, Dumortier HM, den Boer AT, Fransen MF, Nouta J, van der Voort EI, Offringa R, Toes RE, Melief CJ: Activation of dendritic cells that cross-present tumor-derived antigen licenses CD8+ CTL to cause tumor eradication. J Immunol. 2004, 173: 6753-6759.
Article
CAS
PubMed
Google Scholar
Janeway CA, Medzhitov R: Innate immune recognition. Annu Rev Immunol. 2002, 20: 197-216. 10.1146/annurev.immunol.20.083001.084359.
Article
CAS
PubMed
Google Scholar
Chalikonda S, Kivlen MH, O'Malley ME, Eric Dong XD, McCart JA, Gorry MC, Yin XY, Brown CK, Zeh HJ, Guo ZS, Bartlett DL: Oncolytic virotherapy for ovarian carcinomatosis using a replication-selective vaccinia virus armed with a yeast cytosine deaminase gene. Cancer Gene Ther. 2008, 15: 115-125. 10.1038/sj.cgt.7701110.
Article
CAS
PubMed
Google Scholar
Mace AT, Harrow SJ, Ganly I, Brown SM: Cytotoxic effects of the oncolytic herpes simplex virus HSV1716 alone and in combination with cisplatin in head and neck squamous cell carcinoma. Acta Otolaryngol. 2007, 127: 880-887. 10.1080/00016480601075381.
Article
CAS
PubMed
Google Scholar
Moehler MH, Zeidler M, Wilsberg V, Cornelis JJ, Woelfel T, Rommelaere J, Galle PR, Heike M: Parvovirus H-1-induced tumor cell death enhances human immune response in vitro via increased phagocytosis, maturation, and cross-presentation by dendritic cells. Hum Gene Ther. 2005, 16: 996-1005. 10.1089/hum.2005.16.996.
Article
CAS
PubMed
Google Scholar
Kay MA, Glorioso JC, Naldini L: Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med. 2001, 7: 33-40. 10.1038/83324.
Article
CAS
PubMed
Google Scholar
Moehler M, Blechacz B, Weiskopf N, Zeidler M, Stremmel W, Rommelaere J, Galle PR, Cornelis JJ: Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors. Cancer Gene Ther. 2001, 8: 158-167. 10.1038/sj.cgt.7700288.
Article
CAS
PubMed
Google Scholar
Thomas CE, Ehrhardt A, Kay MA: Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet. 2003, 4: 346-358. 10.1038/nrg1066.
Article
CAS
PubMed
Google Scholar
Moehler M, Zeidler M, Schede J, Rommelaere J, Galle PR, Cornelis JJ, Heike M: Oncolytic parvovirus H1 induces release of heat-shock protein HSP72 in susceptible human tumor cells but may not affect primary immune cells. Cancer Gene Ther. 2003, 10: 477-480. 10.1038/sj.cgt.7700591.
Article
CAS
PubMed
Google Scholar
Sieben M, Herzer K, Zeidler M, Heinrichs V, Leuchs B, Schuler M, Cornelis JJ, Galle PR, Rommelaere J, Moehler M: Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein. World J Gastroenterol. 2008, 14: 3819-3828. 10.3748/wjg.14.3819.
Article
CAS
PubMed
PubMed Central
Google Scholar
Rommelaere J, Geletneky K, Angelova AL, Daeffler L, Dinsart C, Kiprianova I, Schlehofer JR, Raykov Z: Oncolytic parvoviruses as cancer therapeutics. Cytokine Growth Factor Rev. 2010, 21: 185-195. 10.1016/j.cytogfr.2010.02.011.
Article
CAS
PubMed
Google Scholar
Bhat R, Dempe S, Dinsart C, Rommelaere J: Enhancement of NK cell antitumor responses using an oncolytic parvovirus. Int J Cancer. 128: 908-919.
Angelova AL, Aprahamian M, Balboni G, Delecluse HJ, Feederle R, Kiprianova I, Grekova SP, Galabov AS, Witzens-Harig M, Ho AD, et al: Oncolytic rat parvovirus H-1PV, a candidate for the treatment of human lymphoma: In vitro and in vivo studies. Mol Ther. 2009, 17: 1164-1172. 10.1038/mt.2009.78.
Article
CAS
PubMed
PubMed Central
Google Scholar
Grekova S, Aprahamian M, Giese N, Schmitt S, Giese T, Falk CS, Daeffler L, Cziepluch C, Rommelaere J, Raykov Z: Immune cells participate in the oncosuppressive activity of parvovirus H-1PV and are activated as a result of their abortive infection with this agent. Cancer Biol Ther. 10: 1280-1289.
Cornelis JJ, Lang SI, Stroh-Dege AY, Balboni G, Dinsart C, Rommelaere J: Cancer gene therapy through autonomous parvovirus--mediated gene transfer. Curr Gene Ther. 2004, 4: 249-261.
Article
CAS
PubMed
Google Scholar
Malerba M, Daeffler L, Rommelaere J, Iggo RD: Replicating parvoviruses that target colon cancer cells. J Virol. 2003, 77: 6683-6691. 10.1128/JVI.77.12.6683-6691.2003.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wetzel K, Menten P, Opdenakker G, Van Damme J, Grone HJ, Giese N, Vecchi A, Sozzani S, Cornelis JJ, Rommelaere J, Dinsart C: Transduction of human MCP-3 by a parvoviral vector induces leukocyte infiltration and reduces growth of human cervical carcinoma cell xenografts. J Gene Med. 2001, 3: 326-337.
Article
CAS
PubMed
Google Scholar
Olijslagers S, Dege AY, Dinsart C, Voorhoeve M, Rommelaere J, Noteborn MH, Cornelis JJ: Potentiation of a recombinant oncolytic parvovirus by expression of Apoptin. Cancer Gene Ther. 2001, 8: 958-965. 10.1038/sj.cgt.7700392.
Article
CAS
PubMed
Google Scholar
Christensen JG: A preclinical review of sunitinib, a multitargeted receptor tyrosine kinase inhibitor with anti-angiogenic and antitumour activities. Ann Oncol. 2007, 18 (Suppl 10): x3-10.
Article
PubMed
Google Scholar
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, et al: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008, 359: 378-390. 10.1056/NEJMoa0708857.
Article
CAS
PubMed
Google Scholar
Lennerz V, Fatho M, Gentilini C, Frye RA, Lifke A, Ferel D, Wolfel C, Huber C, Wolfel T: The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. Proc Natl Acad Sci USA. 2005, 102: 16013-16018. 10.1073/pnas.0500090102.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wang Z, Seliger B, Mike N, Momburg F, Knuth A, Ferrone S: Molecular analysis of the HLA-A2 antigen loss by melanoma cells SK-MEL-29.1.22 and SK-MEL-29.1.29. Cancer Res. 1998, 58: 2149-2157.
CAS
PubMed
Google Scholar
Wolfel T, Van Pel A, Brichard V, Schneider J, Seliger B, Meyer zum Buschenfelde KH, Boon T: Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes. Eur J Immunol. 1994, 24: 759-764. 10.1002/eji.1830240340.
Article
CAS
PubMed
Google Scholar
Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH: Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med. 2000, 192: 1213-1222. 10.1084/jem.192.9.1213.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wrzesinski C, Tesfay L, Salome N, Jauniaux JC, Rommelaere J, Cornelis J, Dinsart C: Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a DNA sequence that restricts parvovirus H-1 in mouse cells. J Virol. 2003, 77: 3851-3858. 10.1128/JVI.77.6.3851-3858.2003.
Article
CAS
PubMed
PubMed Central
Google Scholar
Faisst S, Faisst SR, Dupressoir T, Plaza S, Pujol A, Jauniaux JC, Rhode SL, Rommelaere J: Isolation of a fully infectious variant of parvovirus H-1 supplanting the standard strain in human cells. J Virol. 1995, 69: 4538-4543.
CAS
PubMed
PubMed Central
Google Scholar
Jonuleit H, Giesecke A, Kandemir A, Paragnik L, Knop J, Enk AH: Induction of tumor peptide-specific cytotoxic T cells under serum-free conditions by mature human dendritic cells. Arch Dermatol Res. 2000, 292: 325-332. 10.1007/s004030000144.
Article
CAS
PubMed
Google Scholar
Hristov G, Kramer M, Li J, El-Andaloussi N, Mora R, Daeffler L, Zentgraf H, Rommelaere J, Marchini A: Through its nonstructural protein NS1, parvovirus H-1 induces apoptosis via accumulation of reactive oxygen species. J Virol. 84: 5909-5922.
Rommelaere J, Cornelis JJ: Autonomous Parvoviruses. Monographs in Virology. 2001, 22: 100-129.
Article
Google Scholar
Algarra I, Cabrera T, Garrido F: The HLA crossroad in tumor immunology. Hum Immunol. 2000, 61: 65-73. 10.1016/S0198-8859(99)00156-1.
Article
CAS
PubMed
Google Scholar
Heath WR, Carbone FR: Cross-presentation, dendritic cells, tolerance and immunity. Annu Rev Immunol. 2001, 19: 47-64. 10.1146/annurev.immunol.19.1.47.
Article
CAS
PubMed
Google Scholar
Duverger V, Sartorius U, Klein-Bauernschmitt P, Krammer PH, Schlehofer JR: Enhancement of cisplatin-induced apoptosis by infection with adeno-associated virus type 2. Int J Cancer. 2002, 97: 706-712. 10.1002/ijc.10077.
Article
CAS
PubMed
Google Scholar
Cinatl J, Cinatl J, Michaelis M, Kabickova H, Kotchetkov R, Vogel JU, Doerr HW, Klingebiel T, Driever PH: Potent oncolytic activity of multimutated herpes simplex virus G207 in combination with vincristine against human rhabdomyosarcoma. Cancer Res. 2003, 63: 1508-1514.
CAS
PubMed
Google Scholar
Lyros O, Mueller A, Heidel F, Schimanski CC, Gockel I, Galle PR, Lang H, Moehler M: Analysis of anti-proliferative and chemosensitizing effects of sunitinib on human esophagogastric cancer cells: Synergistic interaction with vandetanib via inhibition of multi-receptor tyrosine kinase pathways. Int J Cancer. 2009
Google Scholar
Wagner AD, Moehler M: Development of targeted therapies in advanced gastric cancer: promising exploratory steps in a new era. Curr Opin Oncol. 2009, 21: 381-385. 10.1097/CCO.0b013e32832c42e0.
Article
CAS
PubMed
Google Scholar
Enderlin M, Kleinmann EV, Struyf S, Buracchi C, Vecchi A, Kinscherf R, Kiessling F, Paschek S, Sozzani S, Rommelaere J, et al: TNF-alpha and the IFN-gamma-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma. Cancer Gene Ther. 2009, 16: 149-160. 10.1038/cgt.2008.62.
Article
CAS
PubMed
Google Scholar
Angelova AL, Aprahamian M, Grekova SP, Hajri A, Leuchs B, Giese NA, Dinsart C, Herrmann A, Balboni G, Rommelaere J, Raykov Z: Improvement of gemcitabine-based therapy of pancreatic carcinoma by means of oncolytic parvovirus H-1PV. Clin Cancer Res. 2009, 15: 511-519. 10.1158/1078-0432.CCR-08-1088.
Article
CAS
PubMed
Google Scholar
Cepeda V, Fuertes MA, Castilla J, Alonso C, Quevedo C, Perez JM: Biochemical mechanisms of cisplatin cytotoxicity. Anticancer Agents Med Chem. 2007, 7: 3-18. 10.2174/187152007779314044.
Article
CAS
PubMed
Google Scholar
Jordan MA, Wilson L: Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004, 4: 253-265. 10.1038/nrc1317.
Article
CAS
PubMed
Google Scholar
Tuve S, Racek T, Niemetz A, Schultz J, Soengas MS, Putzer BM: Adenovirus-mediated TA-p73beta gene transfer increases chemosensitivity of human malignant melanomas. Apoptosis. 2006, 11: 235-243. 10.1007/s10495-006-3407-0.
Article
CAS
PubMed
Google Scholar
Lee JH, Roh MS, Lee YK, Kim MK, Han JY, Park BH, Trown P, Kirn DH, Hwang TH: Oncolytic and immunostimulatory efficacy of a targeted oncolytic poxvirus expressing human GM-CSF following intravenous administration in a rabbit tumor model. Cancer Gene Ther. 2010, 17: 73-79. 10.1038/cgt.2009.50.
Article
CAS
PubMed
Google Scholar
McCart JA, Puhlmann M, Lee J, Hu Y, Libutti SK, Alexander HR, Bartlett DL: Complex interactions between the replicating oncolytic effect and the enzyme/prodrug effect of vaccinia-mediated tumor regression. Gene Ther. 2000, 7: 1217-1223. 10.1038/sj.gt.3301237.
Article
CAS
PubMed
Google Scholar
Freytag SO, Stricker H, Pegg J, Paielli D, Pradhan DG, Peabody J, DePeralta-Venturina M, Xia X, Brown S, Lu M, Kim JH: Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate-to high-risk prostate cancer. Cancer Res. 2003, 63: 7497-7506.
CAS
PubMed
Google Scholar
Khuri FR, Nemunaitis J, Ganly I, Arseneau J, Tannock IF, Romel L, Gore M, Ironside J, MacDougall RH, Heise C, et al: a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med. 2000, 6: 879-885. 10.1038/78638.
Article
CAS
PubMed
Google Scholar
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, et al: Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. Mol Ther. 2006, 14: 779-788. 10.1016/j.ymthe.2006.08.008.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wakimoto H, Fulci G, Tyminski E, Chiocca EA: Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis. Gene Ther. 2004, 11: 214-223. 10.1038/sj.gt.3302143.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lun XQ, Jang JH, Tang N, Deng H, Head R, Bell JC, Stojdl DF, Nutt CL, Senger DL, Forsyth PA, McCart JA: Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide. Clin Cancer Res. 2009, 15: 2777-2788. 10.1158/1078-0432.CCR-08-2342.
Article
CAS
PubMed
Google Scholar
Thomas MA, Spencer JF, Toth K, Sagartz JE, Phillips NJ, Wold WS: Immunosuppression enhances oncolytic adenovirus replication and antitumor efficacy in the Syrian hamster model. Mol Ther. 2008, 16: 1665-1673. 10.1038/mt.2008.162.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kottke T, Thompson J, Diaz RM, Pulido J, Willmon C, Coffey M, Selby P, Melcher A, Harrington K, Vile RG: Improved systemic delivery of oncolytic reovirus to established tumors using preconditioning with cyclophosphamide-mediated Treg modulation and interleukin-2. Clin Cancer Res. 2009, 15: 561-569. 10.1158/1078-0432.CCR-08-1688.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen G, Zhou J, Gao Q, Huang X, Li K, Zhuang L, Huang M, Xu G, Wang S, Lu Y, Ma D: Oncolytic adenovirus-mediated transfer of the antisense chk2 selectively inhibits tumor growth in vitro and in vivo. Cancer Gene Ther. 2006, 13: 930-939. 10.1038/sj.cgt.7700967.
Article
CAS
PubMed
Google Scholar
Zhou J, Gao Q, Chen G, Huang X, Lu Y, Li K, Xie D, Zhuang L, Deng J, Ma D: Novel oncolytic adenovirus selectively targets tumor-associated polo-like kinase 1 and tumor cell viability. Clin Cancer Res. 2005, 11: 8431-8440. 10.1158/1078-0432.CCR-05-1085.
Article
CAS
PubMed
Google Scholar
Motta I, Andre F, Lim A, Tartaglia J, Cox WI, Zitvogel L, Angevin E, Kourilsky P: Cross-presentation by dendritic cells of tumor antigen expressed in apoptotic recombinant canarypox virus-infected dendritic cells. J Immunol. 2001, 167: 1795-1802.
Article
CAS
PubMed
Google Scholar
Prestwich RJ, Errington F, Steele LP, Ilett EJ, Morgan RS, Harrington KJ, Pandha HS, Selby PJ, Vile RG, Melcher AA: Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus. J Immunol. 2009, 183: 4312-4321. 10.4049/jimmunol.0901074.
Article
CAS
PubMed
Google Scholar
Rolle A, Olweus J: Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures. Apmis. 2009, 117: 413-426. 10.1111/j.1600-0463.2009.02449.x.
Article
CAS
PubMed
Google Scholar
Ramakrishna E, Woller N, Mundt B, Knocke S, Gurlevik E, Saborowski M, Malek N, Manns MP, Wirth T, Kuhnel F, Kubicka S: Antitumoral immune response by recruitment and expansion of dendritic cells in tumors infected with telomerase-dependent oncolytic viruses. Cancer Res. 2009, 69: 1448-1458. 10.1158/0008-5472.CAN-08-1160.
Article
CAS
PubMed
Google Scholar
Berwin B, Reed RC, Nicchitta CV: Virally induced lytic cell death elicits the release of immunogenic GRP94/gp96. J Biol Chem. 2001, 276: 21083-21088. 10.1074/jbc.M101836200.
Article
CAS
PubMed
Google Scholar
Kaneno R, Shurin GV, Tourkova IL, Shurin MR: Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. J Transl Med. 2009, 7: 58-10.1186/1479-5876-7-58.
Article
PubMed
PubMed Central
Google Scholar
Pandha HS, Heinemann L, Simpson GR, Melcher A, Prestwich R, Errington F, Coffey M, Harrington KJ, Morgan R: Synergistic effects of oncolytic reovirus and cisplatin chemotherapy in murine malignant melanoma. Clin Cancer Res. 2009, 15: 6158-6166. 10.1158/1078-0432.CCR-09-0796.
Article
CAS
PubMed
Google Scholar
Hipp MM, Hilf N, Walter S, Werth D, Brauer KM, Radsak MP, Weinschenk T, Singh-Jasuja H, Brossart P: Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood. 2008, 111: 5610-5620. 10.1182/blood-2007-02-075945.
Article
CAS
PubMed
Google Scholar
Finke JH, Rini B, Ireland J, Rayman P, Richmond A, Golshayan A, Wood L, Elson P, Garcia J, Dreicer R, Bukowski R: Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients. Clin Cancer Res. 2008, 14: 6674-6682. 10.1158/1078-0432.CCR-07-5212.
Article
CAS
PubMed
Google Scholar
Blattman JN, Greenberg PD: Cancer immunotherapy: a treatment for the masses. Science. 2004, 305: 200-205. 10.1126/science.1100369.
Article
CAS
PubMed
Google Scholar