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Figure 6 | BMC Cancer

Figure 6

From: Activation of the human immune system by chemotherapeutic or targeted agents combined with the oncolytic parvovirus H-1

Figure 6

DC maturation and cytokine production after incubation with H-1PV and sunitinib treated SK29-Mel cells. A: Activation of DC by SK29-Mel cells treated with H-1PV (MOI = 20 PFU/cell) and/or sunitinib. Immature DC were incubated for 2 days with different lysates as indicated. Sunitinib 5 μg/ml was used. The maturation marker CD86 was measured via FACScan. B: CTL IL-6-production. CTL were co-cultured with TCL-incubated DC for 1 day in a 96-well plate. IL-6 levels were determined using ELISA.

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