Hammerschmidt R: PHYTOALEXINS: What Have We Learned After 60 Years?. Annu Rev Phytopathol. 1999, 37: 285-306. 10.1146/annurev.phyto.37.1.285.
Article
CAS
PubMed
Google Scholar
Signorelli P, Ghidoni R: Resveratrol as an anticancer nutrient: molecular basis, open questions and promises. J Nutr Biochem. 2005, 16 (8): 449-466. 10.1016/j.jnutbio.2005.01.017.
Article
CAS
PubMed
Google Scholar
Gusman J, Malonne H, Atassi G: A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis. 2001, 22 (8): 1111-1117. 10.1093/carcin/22.8.1111.
Article
CAS
PubMed
Google Scholar
Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, et al: Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 1997, 275 (5297): 218-220. 10.1126/science.275.5297.218.
Article
CAS
PubMed
Google Scholar
Kelloff GJ, Crowell JA, Steele VE, Lubet RA, Malone WA, Boone CW, Kopelovich L, Hawk ET, Lieberman R, Lawrence JA, et al: Progress in cancer chemoprevention: development of diet-derived chemopreventive agents. J Nutr. 2000, 130 (2S Suppl): 467S-471S.
CAS
PubMed
Google Scholar
Athar M, Back JH, Tang X, Kim KH, Kopelovich L, Bickers DR, Kim AL: Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol. 2007, 224 (3): 274-283. 10.1016/j.taap.2006.12.025.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gao X, Xu YX, Divine G, Janakiraman N, Chapman RA, Gautam SC: Disparate in vitro and in vivo antileukemic effects of resveratrol, a natural polyphenolic compound found in grapes. J Nutr. 2002, 132 (7): 2076-2081.
CAS
PubMed
Google Scholar
Mertens-Talcott SU, Percival SS: Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells. Cancer Lett. 2005, 218 (2): 141-151. 10.1016/j.canlet.2004.06.007.
Article
CAS
PubMed
Google Scholar
Puissant A, Grosso S, Jacquel A, Belhacene N, Colosetti P, Cassuto JP, Auberger P: Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol. FASEB J. 2008, 22 (6): 1894-1904. 10.1096/fj.07-101394.
Article
CAS
PubMed
Google Scholar
Komina O, Wesierska-Gadek J: Action of resveratrol alone or in combination with roscovitine, a CDK inhibitor, on cell cycle progression in human HL-60 leukemia cells. Biochem Pharmacol. 2008, 76 (11): 1554-1562. 10.1016/j.bcp.2008.08.002.
Article
CAS
PubMed
Google Scholar
Chakraborty PK, Mustafi SB, Ganguly S, Chatterjee M, Raha S: Resveratrol induces apoptosis in K562 (chronic myelogenous leukemia) cells by targeting a key survival protein, heat shock protein 70. Cancer Sci. 2008, 99 (6): 1109-1116. 10.1111/j.1349-7006.2008.00809.x.
Article
CAS
PubMed
Google Scholar
Cecchinato V, Chiaramonte R, Nizzardo M, Cristofaro B, Basile A, Sherbet GV, Comi P: Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells. Biochem Pharmacol. 2007, 74 (11): 1568-1574. 10.1016/j.bcp.2007.08.001.
Article
CAS
PubMed
Google Scholar
Jeong SH, Jo WS, Song S, Suh H, Seol SY, Leem SH, Kwon TK, Yoo YH: A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells. Biochem Pharmacol. 2009, 77 (8): 1337-1347. 10.1016/j.bcp.2009.01.002.
Article
CAS
PubMed
Google Scholar
Aggarwal BB, Bhardwaj A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y: Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res. 2004, 24 (5A): 2783-2840.
CAS
PubMed
Google Scholar
Fulda S, Debatin KM: Resveratrol modulation of signal transduction in apoptosis and cell survival: a mini-review. Cancer Detect Prev. 2006, 30 (3): 217-223. 10.1016/j.cdp.2006.03.007.
Article
CAS
PubMed
Google Scholar
Viswanathan M, Kim SK, Berdichevsky A, Guarente L: A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Dev Cell. 2005, 9 (5): 605-615. 10.1016/j.devcel.2005.09.017.
Article
CAS
PubMed
Google Scholar
Woo KJ, Lee TJ, Lee SH, Lee JM, Seo JH, Jeong YJ, Park JW, Kwon TK: Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells. Biochem Pharmacol. 2007, 73 (1): 68-76. 10.1016/j.bcp.2006.09.015.
Article
CAS
PubMed
Google Scholar
Chinta SJ, Poksay KS, Kaundinya G, Hart M, Bredesen DE, Andersen JK, Rao RV: Endoplasmic Reticulum Stress-Induced Cell Death in Dopaminergic Cells: Effect of Resveratrol. J Mol Neurosci. 2009
Google Scholar
Patil C, Walter P: Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr Opin Cell Biol. 2001, 13 (3): 349-355. 10.1016/S0955-0674(00)00219-2.
Article
CAS
PubMed
Google Scholar
Kaufman RJ: Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev. 1999, 13 (10): 1211-1233. 10.1101/gad.13.10.1211.
Article
CAS
PubMed
Google Scholar
Xu C, Bailly-Maitre B, Reed JC: Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest. 2005, 115 (10): 2656-2664. 10.1172/JCI26373.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kaufman RJ: Orchestrating the unfolded protein response in health and disease. J Clin Invest. 2002, 110 (10): 1389-1398.
Article
CAS
PubMed
PubMed Central
Google Scholar
Urano F, Bertolotti A, Ron D: IRE1 and efferent signaling from the endoplasmic reticulum. J Cell Sci. 2000, 113 (Pt 21): 3697-3702.
CAS
PubMed
Google Scholar
Brewer JW, Diehl JA: PERK mediates cell-cycle exit during the mammalian unfolded protein response. Proc Natl Acad Sci USA. 2000, 97 (23): 12625-12630. 10.1073/pnas.220247197.
Article
CAS
PubMed
PubMed Central
Google Scholar
Brewer JW, Hendershot LM, Sherr CJ, Diehl JA: Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression. Proc Natl Acad Sci USA. 1999, 96 (15): 8505-8510. 10.1073/pnas.96.15.8505.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zinszner H, Kuroda M, Wang X, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL, Ron D: CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 1998, 12 (7): 982-995. 10.1101/gad.12.7.982.
Article
CAS
PubMed
PubMed Central
Google Scholar
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ: Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol. 2001, 21 (4): 1249-1259. 10.1128/MCB.21.4.1249-1259.2001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Harding HP, Zeng H, Zhang Y, Jungries R, Chung P, Plesken H, Sabatini DD, Ron D: Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival. Mol Cell. 2001, 7 (6): 1153-1163. 10.1016/S1097-2765(01)00264-7.
Article
CAS
PubMed
Google Scholar
Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D: Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell. 2000, 5 (5): 897-904. 10.1016/S1097-2765(00)80330-5.
Article
CAS
PubMed
Google Scholar
Oyadomari S, Mori M: Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 2004, 11 (4): 381-389. 10.1038/sj.cdd.4401373.
Article
CAS
PubMed
Google Scholar
Boyce M, Yuan J: Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ. 2006, 13 (3): 363-373. 10.1038/sj.cdd.4401817.
Article
CAS
PubMed
Google Scholar
Harding HP, Calfon M, Urano F, Novoa I, Ron D: Transcriptional and translational control in the Mammalian unfolded protein response. Annu Rev Cell Dev Biol. 2002, 18: 575-599. 10.1146/annurev.cellbio.18.011402.160624.
Article
CAS
PubMed
Google Scholar
Yoshida H, Okada T, Haze K, Yanagi H, Yura T, Negishi M, Mori K: ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response. Mol Cell Biol. 2000, 20 (18): 6755-6767. 10.1128/MCB.20.18.6755-6767.2000.
Article
CAS
PubMed
PubMed Central
Google Scholar
Yoshida H, Haze K, Yanagi H, Yura T, Mori K: Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J Biol Chem. 1998, 273 (50): 33741-33749. 10.1074/jbc.273.50.33741.
Article
CAS
PubMed
Google Scholar
Shen J, Prywes R: ER stress signaling by regulated proteolysis of ATF6. Methods. 2005, 35 (4): 382-389. 10.1016/j.ymeth.2004.10.011.
Article
CAS
PubMed
Google Scholar
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, et al: Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol. 2004, 165 (3): 347-356. 10.1083/jcb.200310015.
Article
CAS
PubMed
PubMed Central
Google Scholar
Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P: Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis. Cancer Res. 2007, 67 (20): 9750-9761. 10.1158/0008-5472.CAN-07-2047.
Article
CAS
PubMed
Google Scholar
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, et al: Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest. 2009, 119 (10): 2925-2941. 10.1172/JCI38857.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kelloff GJ: Perspectives on cancer chemoprevention research and drug development. Adv Cancer Res. 2000, 78: 199-334. full_text.
Article
CAS
PubMed
Google Scholar
Pervaiz S: Resveratrol: from grapevines to mammalian biology. FASEB J. 2003, 17 (14): 1975-1985. 10.1096/fj.03-0168rev.
Article
CAS
PubMed
Google Scholar
Ferry-Dumazet H, Garnier O, Mamani-Matsuda M, Vercauteren J, Belloc F, Billiard C, Dupouy M, Thiolat D, Kolb JP, Marit G, et al: Resveratrol inhibits the growth and induces the apoptosis of both normal and leukemic hematopoietic cells. Carcinogenesis. 2002, 23 (8): 1327-1333. 10.1093/carcin/23.8.1327.
Article
CAS
PubMed
Google Scholar
She QB, Bode AM, Ma WY, Chen NY, Dong Z: Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. Cancer Res. 2001, 61 (4): 1604-1610.
CAS
PubMed
Google Scholar
Lai WL, Wong NS: The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells. Exp Cell Res. 2008, 314 (8): 1667-1682. 10.1016/j.yexcr.2008.02.002.
Article
CAS
PubMed
Google Scholar
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P: IRE1 signaling affects cell fate during the unfolded protein response. Science. 2007, 318 (5852): 944-949. 10.1126/science.1146361.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wek RC, Jiang HY, Anthony TG: Coping with stress: eIF2 kinases and translational control. Biochem Soc Trans. 2006, 34: (Pt 1):7-11.
Article
Google Scholar
Debnath J, Baehrecke EH, Kroemer G: Does autophagy contribute to cell death?. Autophagy. 2005, 1 (2): 66-74. 10.4161/auto.1.2.1738.
Article
CAS
PubMed
Google Scholar
Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, et al: The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. Oncogene. 2003, 22 (40): 6220-6230. 10.1038/sj.onc.1206827.
Article
CAS
PubMed
Google Scholar
Lovat PE, Oliverio S, Corazzari M, Rodolfo C, Ranalli M, Goranov B, Melino G, Redfern CP, Piacentini M: Bak: a downstream mediator of fenretinide-induced apoptosis of SH-SY5Y neuroblastoma cells. Cancer Res. 2003, 63 (21): 7310-7313.
CAS
PubMed
Google Scholar
Tinhofer I, Bernhard D, Senfter M, Anether G, Loeffler M, Kroemer G, Kofler R, Csordas A, Greil R: Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2. FASEB J. 2001, 15 (9): 1613-1615.
CAS
PubMed
Google Scholar
Duarte J, Andriambeloson E, Diebolt M, Andriantsitohaina R: Wine polyphenols stimulate superoxide anion production to promote calcium signaling and endothelial-dependent vasodilatation. Physiol Res. 2004, 53 (6): 595-602.
CAS
PubMed
Google Scholar
Smith JJ, Kenney RD, Gagne DJ, Frushour BP, Ladd W, Galonek HL, Israelian K, Song J, Razvadauskaite G, Lynch AV, et al: Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo. BMC Syst Biol. 2009, 3: 31-10.1186/1752-0509-3-31.
Article
PubMed
PubMed Central
Google Scholar