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  1. The present study aimed at evaluating the efficacy of Raltitrexed, a specific thymidilate synthase inhibitor, in patients with advanced colorectal cancer (ACC) in relapse (>8 weeks) after a prior response or d...

    Authors: Nicolas Tsavaris, Christos Kosmas, Maria Vadiaka and Christos Koufos
    Citation: BMC Cancer 2002 2:2
  2. Intraoperative radiation therapy (IORT) is one of the methods used to deliver a large single dose to the tumor tissue while reducing the exposure of normal surrounding tissue. However, the usefulness of intrao...

    Authors: Kenji Nemoto, Yoshihiro Ogawa, Haruo Matsushita, Ken Takeda, Yoshihiro Takai, Shogo Yamada and Toshihiro Kumabe
    Citation: BMC Cancer 2002 2:1
  3. The effectiveness of neoadjuvant treatment (NT) prior to resection of squamous cell carcinoma of the esophagus (SCCE) in terms of prolonged survival has not been proven by randomized trials. Facing considerabl...

    Authors: Joachim W Heise, Hansjörg Heep, Thomas Frieling, Mario Sarbia, Karl A Hartmann and Hans-Dietrich Röher
    Citation: BMC Cancer 2001 1:20
  4. STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and phosphorylation of STAT3 in 2 rat prostatic epit...

    Authors: Beverly E Barton, Thomas F Murphy, Patricia Adem, Richard A Watson, Robert J Irwin and Hosea F Huang
    Citation: BMC Cancer 2001 1:19
  5. Antagonistic analogues of GnRH for the treatment of prostate cancer may be used clinically in persons for whom return to fertility after such treatment is important or desirable. The purpose of this study was,...

    Authors: Janusz W Kostanski, Ge Jiang, Bhas A Dani, Santos B Murty, Wei Qiu, Bruce Schrier, B C Thanoo and Patrick P DeLuca
    Citation: BMC Cancer 2001 1:18
  6. We previously reported that the α-1 chain of type 11 collagen (COL11A1), not normally expressed in the colon, was up-regulated in stromal fibroblasts in most sporadic colorectal carcinomas. Patients with germline...

    Authors: Heléne Fischer, Sima Salahshor, Roger Stenling, Jan Björk, Gudrun Lindmark, Lennart Iselius, Carlos Rubio and Annika Lindblom
    Citation: BMC Cancer 2001 1:17
  7. The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the expression or function of this complex results in loss of...

    Authors: Chen Huiping, Sigrun Kristjansdottir, Jon G Jonasson, Jonas Magnusson, Valgardur Egilsson and Sigurdur Ingvarsson
    Citation: BMC Cancer 2001 1:16
  8. We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The objective of this study was to determine if t...

    Authors: Matthew Pavao, Yue-Hua Huang, Laurie J Hafer, Robert B Moreland and Abdulmaged M Traish
    Citation: BMC Cancer 2001 1:15
  9. Since Fuchs' report in 1999, the reported protective effect of dietary fiber from colorectal carcinogenesis has led many researchers to question its real benefit. The aim of this study is to evaluate the assoc...

    Authors: Shigeyuki Nakaji, Tadashi Shimoyama, Takashi Umeda, Juichi Sakamoto, Shuji Katsura, Kazuo Sugawara and David Baxter
    Citation: BMC Cancer 2001 1:14
  10. The role of telomerase activation in the expression and/or maintenance of drug resistance is not clearly understood. Therefore, we investigated the relationships, among the telomerase activity, telomere length...

    Authors: Noritsugu Kuranaga, Nariyoshi Shinomiya and Hidetaka Mochizuki
    Citation: BMC Cancer 2001 1:10
  11. Loss of activity of tumor suppressor genes is considered a fundamental step in a genetic model of carcinogenesis. Altered expression of the p53 and the Deleted in Colon Cancer (DCC) proteins has been described...

    Authors: Francesco Graziano, Stefano Cascinu, Maria Pia Staccioli, Vincenzo Catalano, Maria Cristina Rossi, Anna Maria Baldelli, Paolo Giordani, Pietro Muretto and Giuseppina Catalano
    Citation: BMC Cancer 2001 1:9
  12. The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer may represent different entities of the disease, this s...

    Authors: Annette P Høyer, Torben Jørgensen, Fritz Rank and Philippe Grandjean
    Citation: BMC Cancer 2001 1:8
  13. Invasion and metastasis is a complex process governed by the interaction of genetically altered tumor cells and the immunological and inflammatory host reponse. Specific T-cells directed against tumor cells an...

    Authors: Iris D Nagtegaal, Corrie AM Marijnen, Elma Klein Kranenbarg, Adri Mulder-Stapel, Jo Hermans, Cornelis JH van de Velde and J Han JM van Krieken
    Citation: BMC Cancer 2001 1:7
  14. Because cells progressing to cancer must proliferate, marker proteins specific to proliferating cells may permit detection of premalignant lesions. Here we compared the sensitivities of a classic proliferation...

    Authors: Dong-Feng Tan, Joel A Huberman, Andrew Hyland, Gregory M Loewen, John SJ Brooks, Amy F Beck, Ivan T Todorov and Gerold Bepler
    Citation: BMC Cancer 2001 1:6
  15. A systematic review of the literature was carried out to determine the role of prophylactic cranial irradiation (PCI) in small cell lung cancer (SCLC) .

    Authors: Anne-Pascale Meert, Marianne Paesmans, Thierry Berghmans, Benoît Martin, Céline Mascaux, Frédéric Vallot, Jean-Marc Verdebout, Jean-Jacques Lafitte and Jean-Paul Sculier
    Citation: BMC Cancer 2001 1:5
  16. Nasopharyngeal carcinoma (NPC) is a rare tumor in most parts of the world but occurs at relatively high frequency among people of Chinese descent. The cytochrome P450 2E1 enzyme (CYP2E1) is responsible for the...

    Authors: Narisorn Kongruttanachok, Sairoong Sukdikul, Surachai Setavarin, Verachai Kerekhjanarong, Pakpoom Supiyaphun, Narin Voravud, Yong Poovorawan and Apiwat Mutirangura
    Citation: BMC Cancer 2001 1:4
  17. We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma.

    Authors: Masaki Tomita, Takanori Ayabe, Yasunori Matsuzaki, Masao Edagawa, Masayuki Maeda, Tetsuya Shimizu, Masaki Hara and Toshio Onitsuka
    Citation: BMC Cancer 2001 1:3
  18. Human papillomavirus (HPV) is a crucial etiological factor for cervical cancer (CC) development. From a diagnostic view-point, the consistent presence of HPV in CC allows the viral DNA to be used as a genetic ...

    Authors: Wichai Pornthanakasem, Kanjana Shotelersuk, Wichai Termrungruanglert, Narin Voravud, Somchai Niruthisard and Apiwat Mutirangura
    Citation: BMC Cancer 2001 1:2
  19. We investigated the chemopreventive action of dietary curcumin on 7,12-dimethylbenz(a)anthracene (DMBA)-initiated and 12,0-tetradecanoylphorbol-13-acetate (TPA)-promoted skin tumor formation in Swiss albino mi...

    Authors: Porn-ngarm Limtrakul, Songyot Anuchapreeda, Suwiwek Lipigorngoson and Floyd W Dunn
    Citation: BMC Cancer 2001 1:1

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