Skip to main content

Articles

Page 256 of 328

  1. The oxidative stress mechanism is of particular interest in the pathogenesis of glioma, given the high rate of oxygen metabolism in the brain. Potential links between polymorphisms of antioxidant genes and gli...

    Authors: Peng Zhao, Lin Zhao, Peng Zou, Ailin Lu, Ning Liu, Wei Yan, Chunsheng Kang, Zhen Fu, Yongping You and Tao Jiang
    Citation: BMC Cancer 2012 12:617
  2. Presence of disseminated tumor cells (DTCs) in bone marrow (BM) after completion of systemic adjuvant treatment predicts reduced survival in breast cancer. The present study explores the use of DTCs to identif...

    Authors: Marit Synnestvedt, Elin Borgen, Erik Wist, Gro Wiedswang, Kjetil Weyde, Terje Risberg, Christian Kersten, Ingvil Mjaaland, Lise Vindi, Cecilie Schirmer, Jahn Martin Nesland and Bjørn Naume
    Citation: BMC Cancer 2012 12:616
  3. Asbestos is the main cause of MPM in industrialized countries. Even since asbestos is banned in most developed countries, the peak wave of MPM incidence is anticipated for the next years due to the long latenc...

    Authors: Ulf Petrausch, Petra C Schuberth, Christian Hagedorn, Alex Soltermann, Sandra Tomaszek, Rolf Stahel, Walter Weder and Christoph Renner
    Citation: BMC Cancer 2012 12:615
  4. Diagnosis of multiple endocrine neoplasia type 1 (MEN1) is commonly based on clinical criteria, and confirmed by genetic testing. In patients without known MEN1-related germline mutations, the possibility of a...

    Authors: Enrico Erdas, Nicola Aste, Luca Pilloni, Angelo Nicolosi, Sergio Licheri, Antonello Cappai, Marco Mastinu, Filomena Cetani, Elena Pardi, Stefano Mariotti and Mariano Pomata
    Citation: BMC Cancer 2012 12:614
  5. In breast cancer, diabetes diagnosed prior to cancer (previously diagnosed) is associated with advanced cancer stage and increased mortality. However, in the general population, 40% of diabetes is undiagnosed ...

    Authors: Robert I Griffiths, Mark D Danese, Michelle L Gleeson and José M Valderas
    Citation: BMC Cancer 2012 12:613
  6. HuR is an RNA-binding protein that post-transcriptionally modulates the expressions of various target genes implicated in carcinogenesis, such as CCNA2 encoding cyclin A. No prior study attempted to evaluate the ...

    Authors: Peir-In Liang, Wei-Ming Li, Yu-Hui Wang, Ting-Feng Wu, Wen-Ren Wu, Alex C Liao, Kun-Hung Shen, Yu-Ching Wei, Chung-Hsi Hsing, Yow-Ling Shiue, Hsuan-Ying Huang, Han-Ping Hsu, Li-Tzon Chen, Ching-Yih Lin, Chein Tai, Chun-Mao Lin…
    Citation: BMC Cancer 2012 12:611
  7. The goal of this study was to identify the clinicopathological factors of co-existing papillary thyroid cancer (PTC) in patients with Hashimoto’s thyroiditis (HT) and provide information to aid in the diagnosi...

    Authors: Ling Zhang, Hui Li, Qing-hai Ji, Yong-xue Zhu, Zhuo-ying Wang, Yu Wang, Cai-ping Huang, Qiang Shen, Duan-shu Li and Yi Wu
    Citation: BMC Cancer 2012 12:610
  8. There is no consensus on the indication for salvage chemoradiotherapy (CRT) after failure of primary chemotherapy for locally advanced pancreatic cancer (LAPC). Here we report on the retrospective analysis of ...

    Authors: Hiroshi Mayahara, Yoshinori Ito, Chigusa Morizane, Hideki Ueno, Takuji Okusaka, Shunsuke Kondo, Naoya Murakami, Madoka Morota, Minako Sumi and Jun Itami
    Citation: BMC Cancer 2012 12:609
  9. The malignant transformation of precancerous colorectal lesions involves progressive alterations at both the molecular and morphologic levels, the latter consisting of increases in size and in the degree of ce...

    Authors: Rosalia Maglietta, Vania Cosma Liuzzi, Elisa Cattaneo, Endre Laczko, Ada Piepoli, Anna Panza, Massimo Carella, Orazio Palumbo, Teresa Staiano, Federico Buffoli, Angelo Andriulli, Giancarlo Marra and Nicola Ancona
    Citation: BMC Cancer 2012 12:608
  10. Malignant glioma is a common primary tumor of the central nervous system. Brevican, an abundant extracellular matrix component in the adult brain, plays a critical role in the process of glioma. The mechanisms...

    Authors: Renquan Lu, Chengsheng Wu, Lin Guo, Yingchao Liu, Wei Mo, Huijie Wang, Jianbo Ding, Eric T Wong and Min Yu
    Citation: BMC Cancer 2012 12:607
  11. An n-6 essential fatty acid, arachidonic acid (ARA) is converted into prostaglandin E2, which is involved in tumour extension. However, it is unclear whether dietary ARA intake leads to cancer in humans. We thus ...

    Authors: Mai Sakai, Saki Kakutani, Chika Horikawa, Hisanori Tokuda, Hiroshi Kawashima, Hiroshi Shibata, Hitomi Okubo and Satoshi Sasaki
    Citation: BMC Cancer 2012 12:606
  12. Neoplastic transformation of cultured cells by a number of oncogenes such as src suppresses gap junctional, intercellular communication (GJIC); however, the role of Src and its effector Signal transducer and acti...

    Authors: Mulu Geletu, Rozanne Arulanandam, Samantha Greer, Aaron Trotman-Grant, Evangelia Tomai and Leda Raptis
    Citation: BMC Cancer 2012 12:605
  13. The aim of this study was to measure the biological characteristics involved in tumorigenesis and the progression of breast cancer in symptomatic and screen-detected carcinomas to identify possible differences.

    Authors: Maximino Redondo, Rafael Funez, Francisco Medina-Cano, Isabel Rodrigo, Mercedes Acebal, Teresa Tellez, M Jose Roldan, M Luisa Hortas, Ana Bellinvia, Teresa Pereda, Laia Domingo, María Morales-Suarez Varela, Maria Sala and Antonio Rueda
    Citation: BMC Cancer 2012 12:604
  14. Chemotherapy induced nausea and vomiting (CINV) remains a major problem that seriously impairs the quality of life (QoL) in cancer patients receiving chemotherapy regimens. Complementary medicines, including h...

    Authors: David Pérol, Jocelyne Provençal, Anne-claire Hardy-Bessard, David Coeffic, Jean-Phillipe Jacquin, Cécile Agostini, Thomas Bachelot, Jean-Paul Guastalla, Xavier Pivot, Jean-Pierre Martin, Agathe Bajard and Isabelle Ray-Coquard
    Citation: BMC Cancer 2012 12:603
  15. Esophageal squamous cell carcinoma (ESCC) shows geographic variations in incidence, with high incidences (>50/105 person-years) in central Asia, including North Eastern Iran (Golestan) and Northern India (Kashmir...

    Authors: Behnoush Abedi-Ardekani, Nazir Ahmad Dar, Mohammad Muzaffar Mir, Showkat Ahmad Zargar, M Muqbool Lone, Ghyslaine Martel-Planche, Stéphanie Villar, Mounia Mounawar, Farrokh Saidi, Reza Malekzadeh and Pierre Hainaut
    Citation: BMC Cancer 2012 12:602
  16. Caldesmon (CaD), a major actin-associated protein, is found in smooth muscle and non-muscle cells. Smooth muscle caldesmon, h-CaD, is a multifunctional protein, and non-muscle cell caldesmon, l-CaD, plays a role ...

    Authors: Kyung-Hee Kim, Seung-Gu Yeo, Won Ki Kim, Dae Yong Kim, Hyun Yang Yeo, Jun Pyu Hong, Hee Jin Chang, Ji Won Park, Sun Young Kim, Byung Chang Kim and Byong Chul Yoo
    Citation: BMC Cancer 2012 12:601
  17. Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker ass...

    Authors: Verena Engelstaedter, Sabine Heublein, Anamur Lan Schumacher, Miriam Lenhard, Helen Engelstaedter, Ulrich Andergassen, Margit Guenthner-Biller, Christina Kuhn, Brigitte Rack, Markus Kupka, Doris Mayr and Udo Jeschke
    Citation: BMC Cancer 2012 12:600
  18. Androgen receptors (AR) are frequently expressed in breast cancers, but their implication in cancer growth is still controversial. In the present study, we further investigated the role of the androgen/AR path...

    Authors: Giorgio Secreto, Elisabetta Venturelli, Elisabetta Meneghini, Maria Luisa Carcangiu, Biagio Paolini, Roberto Agresti, Cristina Pellitteri, Franco Berrino, Massimo Gion, Patrizia Cogliati, Giuseppina Saragò and Andrea Micheli
    Citation: BMC Cancer 2012 12:599
  19. Over recent years a number of novel therapies have shown promise in advanced renal cell carcinoma (RCC). Internationally the standard of care of first-line therapy is sunitinib™, after a clear survival benefit...

    Authors: Fiona J Collinson, Walter M Gregory, Chris McCabe, Helen Howard, Catherine Lowe, DrBarbara Potrata, Sandy Tubeuf, Pat Hanlon, Lucy McParland, T Wah, Peter J Selby, Jenny Hewison, Julia Brown and Janet Brown
    Citation: BMC Cancer 2012 12:598
  20. Plasminogen activator inhibitor 1 (PAI-1) overexpression is an important prognostic and predictive biomarker in human breast cancer. SERBP1, a protein that is supposed to regulate the stability of PAI-1 mRNA, may...

    Authors: Nuran Bektas Serce, Andreas Boesl, Irina Klaman, Sonja von Serényi, Erik Noetzel, Michael F Press, Arno Dimmler, Arndt Hartmann, Jalid Sehouli, Ruth Knuechel, Matthias W Beckmann, Peter A Fasching and Edgar Dahl
    Citation: BMC Cancer 2012 12:597
  21. Several studies have suggested a cancer risk reduction in statin users although the evidence remains weak for stomach cancer. The purpose of this study was to use an exact-matching case–control design to exami...

    Authors: Jeeyun Lee, Soo Hyeon Lee, Kyu Yeon Hur, Sook Young Woo, Sun Woo Kim and Won Ki Kang
    Citation: BMC Cancer 2012 12:596
  22. Asbestos is classified as a human carcinogen, and studies have consistently demonstrated that workplace exposure to it increases the risk of developing lung cancer. Few studies have evaluated risks in populati...

    Authors: Paul J Villeneuve, Marie-Élise Parent, Shelley A Harris and Kenneth C Johnson
    Citation: BMC Cancer 2012 12:595
  23. In the past few years, the number of clinical trials has increased rapidly in East Asia, especially for gastric and hepatobiliary cancer that are prevalent in Asian populations. However, the actual degree of u...

    Authors: Su Jin Lee, Lee Chun Park, Jeeyun Lee, Seonwoo Kim, Moon Ki Choi, Jung Yong Hong, Sylvia Park, Chi Hoon Maeng, Wonjin Chang, Young Saing Kim, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang and Young Suk Park
    Citation: BMC Cancer 2012 12:594
  24. Gamma-synuclein (SNCG) has previously been demonstrated to be significantly correlated with metastatic malignancies; however, in-depth investigation of SNCG in prostate cancer is still lacking. In the present ...

    Authors: Junyi Chen, Li Jiao, Chuanliang Xu, Yongwei Yu, Zhensheng Zhang, Zheng Chang, Zhen Deng and Yinghao Sun
    Citation: BMC Cancer 2012 12:593
  25. To evaluate disease control, overall survival and prognostic factors in patients with locally recurrent rectal cancer after IOERT-containing multimodal therapy.

    Authors: Falk Roeder, Joerg-Michael Goetz, Gregor Habl, Marc Bischof, Robert Krempien, Markus W Buechler, Frank W Hensley, Peter E Huber, Juergen Weitz and Juergen Debus
    Citation: BMC Cancer 2012 12:592
  26. Tamoxifen is used in hormone therapy for estrogen-receptor (ER)-positive breast cancer, but also has chemopreventative effects against ER-negative breast cancers. This study sought to investigate whether oral ...

    Authors: Xueying Sun, Ruohan Jiang, Aneta Przepiorski, Shiva Reddy, Kate P Palmano and Geoffrey W Krissansen
    Citation: BMC Cancer 2012 12:591
  27. Sorafenib is an orally available kinase inhibitor with activity at Raf, PDGFβ and VEGF receptors that is licensed for the treatment of advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Cu...

    Authors: BP Fairfax, S Pratap, ISD Roberts, J Collier, R Kaplan, AM Meade, AW Ritchie, T Eisen, VM Macaulay and A Protheroe
    Citation: BMC Cancer 2012 12:590
  28. The p21 codon 31 single nucleotide polymorphism (SNP), rs1801270, has been linked to cervical cancer but with controversial results. The aims of this study were to investigate the role of p21 SNP-rs1801270 and...

    Authors: Ning Wang, Shizhuo Wang, Qiao Zhang, Yanming Lu, Heng Wei, Wei Li, Shulan Zhang, Duo Yin and Yangling Ou
    Citation: BMC Cancer 2012 12:589
  29. Psoriasin (S100A7) is a member of the S100 gene family. Alteration of Psoriasin expression has previously been reported to play an important role in cancer aggressive behaviour. The current study sought to inv...

    Authors: Mu Hu, Lin Ye, Fiona Ruge, Xiuyi Zhi, Lijian Zhang and Wen G Jiang
    Citation: BMC Cancer 2012 12:588
  30. Despite all benefit provided by established therapies prognosis of gastric cancer remains poor. Targeted inhibition of platelet derived growth factor receptor (PDGFR) by imatinib may influence tumor growth and...

    Authors: Martina Mayr, Karen Becker, Nadine Schulte, Sebastian Belle, Ralf Hofheinz, Annekatrin Krause, Roland M Schmid, Christoph Röcken and Matthias P Ebert
    Citation: BMC Cancer 2012 12:587
  31. Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET). Since interim-PET is an important prognostic tool in Hodgkin l...

    Authors: Sylvia Hartmann, Claudio Agostinelli, Jürgen Diener, Claudia Döring, Stefano Fanti, Pier Luigi Zinzani, Andrea Gallamini, Lothar Bergmann, Stefano Pileri and Martin-Leo Hansmann
    Citation: BMC Cancer 2012 12:586
  32. The clinical implication of Ras/Raf/ERK pathway activity in breast cancer tissue and its association with response to chemotherapy is controversial. We aimed to explore the value of p90RSK phosphorylation, a d...

    Authors: Hyeong-Gon Moon, Jae Kyo Yi, Hee Sung Kim, Hea Young Lee, Kyung-Min Lee, Minju Yi, Sookyung Ahn, Hee-Chul Shin, Ji-hyun Ju, Incheol Shin, Wonshik Han and Dong-Young Noh
    Citation: BMC Cancer 2012 12:585
  33. Liver transplantation is the most effective therapy for cirrhosis-associated hepatocellular carcinoma (HCC) but its utility is limited by post-transplant tumor recurrence. Use of the Milan, size-based criteria...

    Authors: Zhen Zeng, Jinyu Ren, Maura O’Neil, Jie Zhao, Brian Bridges, Josiah Cox, Bashar Abdulkarim, Timothy M Schmitt, Sean C Kumer and Steven A Weinman
    Citation: BMC Cancer 2012 12:584
  34. Brain metastasis is an increasingly common complication for breast cancer patients; approximately 15– 30% of breast cancer patients develop brain metastasis. However, relatively little is known about how these...

    Authors: Hui Liu, Yukinari Kato, Stephanie A Erzinger, Galina M Kiriakova, Yongzhen Qian, Diane Palmieri, Patricia S Steeg and Janet E Price
    Citation: BMC Cancer 2012 12:583
  35. There are limited population-based studies focusing on the chemopreventive effects of selective cyclooxygenase-2 (COX-2) inhibitors against colorectal cancer. The purpose of this study is to assess the trends ...

    Authors: Yi-Hsin Yang, Yea-Huei Kao Yang, Ching-Lan Cheng, Pei-Shan Ho and Ying-Chin Ko
    Citation: BMC Cancer 2012 12:582
  36. Neurotoxicity caused by treatment for a brain tumor is a major cause of neurocognitive decline in survivors. Studies have shown that neurofeedback may enhance neurocognitive functioning. This paper describes t...

    Authors: Marieke A de Ruiter, Antoinette YN Schouten-Van Meeteren, Rosa van Mourik, Tieme WP Janssen, Juliette EM Greidanus, Jaap Oosterlaan and Martha A Grootenhuis
    Citation: BMC Cancer 2012 12:581
  37. Cancer research has devoted most of its energy over the past decades on unraveling the control mechanisms within tumor cells that govern its behavior. From this we know that the onset of cancer is the result o...

    Authors: Marlies E Heuvers, Joachim G Aerts, Robin Cornelissen, Harry Groen, Henk C Hoogsteden and Joost P Hegmans
    Citation: BMC Cancer 2012 12:580
  38. Human tumour xenografts in immune compromised mice are widely used as cancer models because they are easy to reproduce and simple to use in a variety of pre-clinical assessments. Developments in nanomedicine h...

    Authors: Karyn S Ho, Peter C Poon, Shawn C Owen and Molly S Shoichet
    Citation: BMC Cancer 2012 12:579
  39. There is a lack of psychotherapeutic trials of treatments of comorbid depression in cancer patients. Our study determines the efficacy of a manualized short-term psychodynamic psychotherapy and predictors of o...

    Authors: Rüdiger Zwerenz, Manfred E Beutel, Barbara H Imruck, Jörg Wiltink, Antje Haselbacher, Christian Ruckes, Heinz Schmidberger, Gerald Hoffmann, Marcus Schmidt, Uwe Köhler, Dagmar Langanke, Rolf-Dieter Kortmann, Susanne Kuhnt, Gregor Weißflog, Yvette Barthel, Katja Leuteritz…
    Citation: BMC Cancer 2012 12:578
  40. Women with cancer are significantly more likely to fall than women without cancer placing them at higher risk of fall-related fractures, other injuries and disability. Currently, no evidence-based fall prevent...

    Authors: Kerri M Winters-Stone, Fuzhong Li, Fay Horak, Shiuh-Wen Luoh, Jill A Bennett, Lillian Nail and Nathan Dieckmann
    Citation: BMC Cancer 2012 12:577
  41. The M-type phospholipase A2 receptor (PLA2R1) plays a crucial role in several signaling pathways and may act as tumor-suppressor. This study examined the expression and methylation of the PLA2R1 gene in Jurkat an...

    Authors: Mario Menschikowski, Uwe Platzbecker, Albert Hagelgans, Margot Vogel, Christian Thiede, Claudia Schönefeldt, Renate Lehnert, Graeme Eisenhofer and Gabriele Siegert
    Citation: BMC Cancer 2012 12:576
  42. Despite positive results from large phase III clinical trials proved that it is possible to prevent estrogen-responsive breast cancers with selective estrogen receptor modulators and aromatase inhibitors, no s...

    Authors: Matteo Lazzeroni, Aliana Guerrieri-Gonzaga, Davide Serrano, Massimiliano Cazzaniga, Serena Mora, Chiara Casadio, Costantino Jemos, Maria Pizzamiglio, Laura Cortesi, Davide Radice and Bernardo Bonanni
    Citation: BMC Cancer 2012 12:575
  43. Long interspersed nucleotide element 1 (LINE-1) hypomethylation is suggested to play a role in the progression of colorectal cancer (CRC). To assess intra-patient heterogeneity of LINE-1 methylation in CRC and...

    Authors: Aika Matsunoki, Kazuyuki Kawakami, Masanori Kotake, Mami Kaneko, Hirotaka Kitamura, Akishi Ooi, Go Watanabe and Toshinari Minamoto
    Citation: BMC Cancer 2012 12:574
  44. People with lung cancer have substantial symptom burden and more unmet needs than the general cancer population. Physical activity (PA) has been shown to positively influence quality of life (QOL), fatigue and...

    Authors: Haryana M Dhillon, Hidde P van der Ploeg, Melanie L Bell, Michael Boyer, Stephen Clarke and Janette Vardy
    Citation: BMC Cancer 2012 12:572
  45. Optimizing the safety and efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is of clinical relevance. Serum starvation in vitro and short-term food starvation in vivo both stress cells by t...

    Authors: Yandong Shi, Emanuela Felley-Bosco, Thomas M Marti, Katrin Orlowski, Martin Pruschy and Rolf A Stahel
    Citation: BMC Cancer 2012 12:571
  46. Pyloric gland adenoma consists of closely packed pyloric-type glands lined by mucus-secreting cells. To date, approximately 230 cases have been reported, mostly of gastric localization with a tumour size up to...

    Authors: Inga-Marie Schaefer, Silke Cameron, Peter Middel, Kia Homayounfar, Harald Schwörer, Michael Vieth and Lothar Veits
    Citation: BMC Cancer 2012 12:570
  47. Rash, liver dysfunction, and diarrhea are known major adverse events associated with erlotinib and gefitinib. However, clinical trials with gefitinib have reported different proportions of adverse events compa...

    Authors: Tomohiro Suzumura, Tatsuo Kimura, Shinzoh Kudoh, Kanako Umekawa, Misato Nagata, Kuniomi Matsuura, Hidenori Tanaka, Shigeki Mitsuoka, Naruo Yoshimura, Yukimi Kira, Toshiyuki Nakai and Kazuto Hirata
    Citation: BMC Cancer 2012 12:568
  48. With advances in modern radiotherapy (RT), many patients with head and neck (HN) cancer can be effectively cured. However, xerostomia is a common complication in patients after RT for HN cancer. The purpose of...

    Authors: Tsair-Fwu Lee, Pei-Ju Chao, Hung-Yu Wang, Hsuan-Chih Hsu, PaoShu Chang and Wen-Cheng Chen
    Citation: BMC Cancer 2012 12:567

Featured videos

View featured videos from across the BMC-series journals