Skip to main content

Articles

Page 189 of 330

  1. Persistent dysphagia following primary chemoradiation (CRT) for head and neck cancers can have a devastating impact on patients’ quality of life. Single arm studies have shown that the dosimetric sparing of cr...

    Authors: Imran Petkar, Keith Rooney, Justin W. G. Roe, Joanne M. Patterson, David Bernstein, Justine M. Tyler, Marie A. Emson, James P. Morden, Kathrin Mertens, Elizabeth Miles, Matthew Beasley, Tom Roques, Shreerang A. Bhide, Kate L. Newbold, Kevin J. Harrington, Emma Hall…
    Citation: BMC Cancer 2016 16:770
    Content type: Study protocol Published on:

  2. The higher specificity of amino-acid positron emission tomography (AA-PET) in the diagnosis of gliomas, as well as in the differentiation between recurrence and treatment-related alterations, in comparison to ...

    Authors: Oliver Oehlke, Michael Mix, Erika Graf, Tanja Schimek-Jasch, Ursula Nestle, Irina Götz, Sabine Schneider-Fuchs, Astrid Weyerbrock, Irina Mader, Brigitta G. Baumert, Susan C. Short, Philipp T. Meyer, Wolfgang A. Weber and Anca-Ligia Grosu
    Citation: BMC Cancer 2016 16:769
    Content type: Study protocol Published on:

  3. Optimizing patient selection is a necessary step to design better clinical trials. ‘Life expectancy’ is a frequent inclusion criterion in phase II trial protocols, a measure that is subjective and often diffic...

    Authors: Thomas Grellety, Sophie Cousin, Louis Letinier, Pauline Bosco-Lévy, Stéphanie Hoppe, Damien Joly, Nicolas Penel, Simone Mathoulin-Pelissier and Antoine Italiano
    Citation: BMC Cancer 2016 16:768
    Content type: Research article Published on:

  4. Prostate cancer is the most common non-cutaneous malignancy in men. Today most patients may expect to live years following the diagnosis and may thus experience significant morbidity due to disease progression...

    Authors: Eik Bjerre, Ditte Marie Bruun, Anders Tolver, Klaus Brasso, Peter Krustrup, Christoffer Johansen, Robin Christensen, Mikael Rørth and Julie Midtgaard
    Citation: BMC Cancer 2016 16:767
    Content type: Study protocol Published on:

  5. We sought to assess physician interest in molecular prognosic testing for patients with early stage colon cancer, and identify factors associated with the likelihood of test adoption.

    Authors: Ronald E. Myers, Thomas Wolf, Phillip Shwae, Sarah Hegarty, Stephen C. Peiper and Scott A. Waldman
    Citation: BMC Cancer 2016 16:766
    Content type: Research article Published on:

  6. Surgery for advanced gastric cancer (AGC) often includes dissection of splenic hilar lymph nodes (SHLNs). This study compared the safety and effectiveness of different approaches to SHLN dissection for upper- ...

    Authors: Xin Ji, Tao Fu, Zhao-De Bu, Ji Zhang, Xiao-Jiang Wu, Xiang-Long Zong, Zi-Yu Jia, Biao Fan, Yi-Nan Zhang and Jia-Fu Ji
    Citation: BMC Cancer 2016 16:765
    Content type: Research article Published on:

  7. Cachexia is one of the most important causes of cancer-related death. Supplementation with branched-chain amino acids, particularly leucine, has been used to minimise loss of muscle tissue, although few studie...

    Authors: Laís Rosa Viana, Rafael Canevarolo, Anna Caroline Perina Luiz, Raquel Frias Soares, Camila Lubaczeuski, Ana Carolina de Mattos Zeri and Maria Cristina Cintra Gomes-Marcondes
    Citation: BMC Cancer 2016 16:764
    Content type: Research article Published on:

  8. The formation of new lymphatic vessels provides an additional route for tumour cells to metastasize. Therefore, inhibiting lymphangiogenesis represents an interesting target in cancer therapy. First evidence s...

    Authors: Igor Hrgovic, Monika Doll, Johannes Kleemann, Xiao-Fan Wang, Nadja Zoeller, Andreas Pinter, Stefan Kippenberger, Roland Kaufmann and Markus Meissner
    Citation: BMC Cancer 2016 16:763
    Content type: Research article Published on:

  9. Renal cell carcinoma (RCC) is a seventh ranked malignancy with poor prognosis. RCC is lethal at metastatic stage as it does not respond to conventional systemic treatments, and there is an urgent need to find ...

    Authors: Sajjad Karim, Jaudah A. Al-Maghrabi, Hasan M. A. Farsi, Ahmad J. Al-Sayyad, Hans-Juergen Schulten, Abdelbaset Buhmeida, Zeenat Mirza, Alaa A. Al-boogmi, Fai T. Ashgan, Manal M. Shabaad, Hend F. NourEldin, Khalid B. M. Al-Ghamdi, Adel Abuzenadah, Adeel G. A. Chaudhary and Mohammed H. Al-Qahtani
    Citation: BMC Cancer 2016 16(Suppl 2):741
    Content type: Research article Published on:

    This article is part of a Supplement: Volume 16 Supplement 2

  10. Cancer cells, stem cells and cancer stem cells have for a long time played a significant role in the biomedical sciences. Though cancer therapy is more effective than it was a few years ago, the truth is that ...

    Authors: Sara S. Franco, Karolina Szczesna, Maria S. Iliou, Mohammed Al-Qahtani, Ali Mobasheri, Julianna Kobolák and András Dinnyés
    Citation: BMC Cancer 2016 16(Suppl 2):738
    Content type: Review Published on:

    This article is part of a Supplement: Volume 16 Supplement 2

  11. The roles and mechanisms involved in starvation-induced autophagy in mammalian cells have been extensively studied. However, less is known about the potential role for autophagy as a survival pathway in acquir...

    Authors: Baoqing Guo, Adam Tam, Stacey A. Santi and Amadeo M. Parissenti
    Citation: BMC Cancer 2016 16:762
    Content type: Research article Published on:

  12. Overweight and weight gain throughout adult life have been associated with increased risk of breast cancer after the menopause. However the role of body weight at a young age and of the timing of weight gain o...

    Authors: Emilie Cordina-Duverger, Thérèse Truong, Antoinette Anger, Marie Sanchez, Patrick Arveux, Pierre Kerbrat and Pascal Guénel
    Citation: BMC Cancer 2016 16:761
    Content type: Research article Published on:

  13. Targeted therapies based on the molecular and histological features of cancer types are becoming standard practice. The most effective regimen in lung cancers is different between squamous cell carcinoma (SCC)...

    Authors: Kazuya Takamochi, Hiroko Ohmiya, Masayoshi Itoh, Kaoru Mogushi, Tsuyoshi Saito, Kieko Hara, Keiko Mitani, Yasushi Kogo, Yasunari Yamanaka, Jun Kawai, Yoshihide Hayashizaki, Shiaki Oh, Kenji Suzuki and Hideya Kawaji
    Citation: BMC Cancer 2016 16:760
    Content type: Research article Published on:

  14. Curcuminoids of the spice turmeric and their enhanced derivatives have much potential as cancer treatments. They act on a wide variety of biological pathways, including those regulating cell division and circa...

    Authors: Ashapurna Sarma, Vishal P. Sharma, Arindam B. Sarkar, M. Chandra Sekar, Karunakar Samuel and Michael E. Geusz
    Citation: BMC Cancer 2016 16:759
    Content type: Research article Published on:

  15. Arterial hyperenhancement and washout on computed tomography and magnetic resonance imaging (MRI) are described by all major guidelines as specific criteria for non-invasive diagnosis of hepatocellular carcino...

    Authors: Roman Kloeckner, Daniel Pinto dos Santos, Karl-Friedrich Kreitner, Anne Leicher-Düber, Arndt Weinmann, Jens Mittler and Christoph Düber
    Citation: BMC Cancer 2016 16:758
    Content type: Research article Published on:

  16. This prospective study aimed to compare dose volume histograms (DVH) of the breasts and organs at risk (OARs) of whole breast radiotherapy in the supine and prone positions, and frequency and severity of acute...

    Authors: Kana Takahashi, Madoka Morota, Yoshikazu Kagami, Hiroyuki Okamoto, Shuhei Sekii, Koji Inaba, Naoya Murakami, Hiroshi Igaki, Yoshinori Ito, Takashi Uno and Jun Itami
    Citation: BMC Cancer 2016 16:757
    Content type: Research article Published on:

  17. Although cis-diamminedichloro-platinum (CDDP) exhibits strong therapeutic effects in cancer chemotherapy, its adverse effects such as peripheral neuropathy, nephropathy, and vomiting are dose-limiting factors. Pr...

    Authors: Yoshihiro Seto, Fumiyasu Okazaki, Keiji Horikawa, Jing Zhang, Hitoshi Sasaki and Hideto To
    Citation: BMC Cancer 2016 16:756
    Content type: Research article Published on:

  18. Cancer makes up a large and increasing proportion of excess mortality for indigenous, marginalised and socioeconomically deprived populations, and much of this inequality is preventable. This study aimed to de...

    Authors: Andrea M. Teng, June Atkinson, George Disney, Nick Wilson, Diana Sarfati, Melissa McLeod and Tony Blakely
    Citation: BMC Cancer 2016 16:755
    Content type: Research article Published on:

  19. Fluorouracil implants are widely used in peritoneal interstitial chemotherapy. Curative effects have been obtained, but implants have also caused some complications.

    Authors: Yang-Yang Shen, Hong-Wei Qin, Jian-Bo Zhang, Zhen-Dan Wang, Pang Li, Kai Pang, Bo Zhang, Sheng Li and Kai Cui
    Citation: BMC Cancer 2016 16:754
    Content type: Case report Published on:

  20. Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, can be secreted by most cell types and released in perhaps all biological fluids. EVs contain multiple proteins, specific ...

    Authors: Yang Jin, Keyan Chen, Zongying Wang, Yan Wang, Jianzhi Liu, Li Lin, Yong Shao, Lihua Gao, Huihui Yin, Cong Cui, Zhaoli Tan, Liejun Liu, Chuanhua Zhao, Gairong Zhang, Ru Jia, Lijuan Du…
    Citation: BMC Cancer 2016 16:753
    Content type: Research article Published on:

  21. Platinum-based systemic chemotherapy is considered the backbone for management of advanced urothelial carcinomas. However there is a lack of real world data on the use of such chemotherapy regimens, on patient...

    Authors: N. Houédé, G. Locker, C. Lucas, H. Soto Parra, U. Basso, D. Spaeth, R. Tambaro, L. Basterretxea, F. Morelli, C. Theodore, L. Lusuardi, N. Lainez, A. Guillot, G. Tonini, J. Bielle and X. Garcia Del Muro
    Citation: BMC Cancer 2016 16:752
    Content type: Research article Published on:

  22. The associations between microRNAs and lung cancer have received increasing attention. This study assess the association between polymorphisms in miR-135a-2, miR-219-2 and miR-211 genes and the risk of lung ca...

    Authors: Zhihua Yin, Zhigang Cui, Hang li, Yangwu Ren, Biyun Qian, Nathaniel Rothman, Qing Lan and Baosen Zhou
    Citation: BMC Cancer 2016 16:751
    Content type: Research article Published on:

  23. After the approval of pazopanib for the treatment of soft tissue sarcoma (STS), pneumothorax was reported as an unexpected adverse event during pazopanib treatment. The incidence and risk factors of pneumothor...

    Authors: Kenji Nakano, Noriko Motoi, Junichi Tomomatsu, Tabu Gokita, Keisuke Ae, Taisuke Tanizawa, Seiichi Matsumoto and Shunji Takahashi
    Citation: BMC Cancer 2016 16:750
    Content type: Research article Published on:

  24. Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumours with a typical 5 year survival rate of <40 %. DNA methylation in tumour-suppressor genes often occurs at an early stage of tumo...

    Authors: Yenkai Lim, Yunxia Wan, Dimitrios Vagenas, Dmitry A. Ovchinnikov, Chris F. L. Perry, Melissa J. Davis and Chamindie Punyadeera
    Citation: BMC Cancer 2016 16:749
    Content type: Research article Published on:

  25. Chromosome 7 open reading frame 24 (C7orf24) was originally identified as a highly expressed protein in various types of cancer, and later shown to be a γ-glutamylcyclotransferase (GGCT). GGCT depletion in can...

    Authors: Kengo Matsumura, Susumu Nakata, Keiko Taniguchi, Hiromi Ii, Eishi Ashihara, Susumu Kageyama, Akihiro Kawauchi and Tatsuhiro Yoshiki
    Citation: BMC Cancer 2016 16:748
    Content type: Research article Published on:

  26. A totally implantable venous access device (TIVAD) provides reliable, long-term vascular access and improves patients’ quality of life. The wide use of TIVADs is associated with important complications. A meta...

    Authors: Shaoyong Wu, Jingxiu Huang, Zongming Jiang, Zhimei Huang, Handong Ouyang, Li Deng, Wenqian Lin, Jin Guo and Weian Zeng
    Citation: BMC Cancer 2016 16:747
    Content type: Research article Published on:

  27. Several studies show that bone marrow (BM) microenvironment and hypoxia condition can promote the survival of leukemic cells and induce resistance to anti-leukemic drugs. However, the molecular mechanism for c...

    Authors: C. Petit, F. Gouel, I. Dubus, C. Heuclin, K. Roget and J. P. Vannier
    Citation: BMC Cancer 2016 16:746
    Content type: Research article Published on:

  28. Sequential biopsy of breast cancer is used to assess biomarker effects and drug efficacy. The preoperative “window of opportunity” setting is advantageous to test biomarker changes in response to therapeutic a...

    Authors: Sirwan M. Hadad, Lee B. Jordan, Pankaj G. Roy, Colin A. Purdie, Takayuki Iwamoto, Lajos Pusztai, Stacy L. Moulder-Thompson and Alastair M. Thompson
    Citation: BMC Cancer 2016 16:745
    Content type: Research article Published on:

  29. While programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) checkpoint inhibitors have activity in a proportion of patients with advanced bladder cancer, strongly predictive and prognostic biomarkers...

    Authors: Archana Anantharaman, Terence Friedlander, David Lu, Rachel Krupa, Gayatri Premasekharan, Jeffrey Hough, Matthew Edwards, Rosa Paz, Karla Lindquist, Ryon Graf, Adam Jendrisak, Jessica Louw, Lyndsey Dugan, Sarah Baird, Yipeng Wang, Ryan Dittamore…
    Citation: BMC Cancer 2016 16:744
    Content type: Research article Published on:

  30. The incidence rate has been increasing for superficial head and neck squamous cell carcinoma (HNSCC) discovered through surveillance endoscopic study using narrow band imaging (NBI), a procedure mainly used fo...

    Authors: Hiroshi Nakamura, Tomonori Yano, Satoshi Fujii, Tomohiro Kadota, Toshifumi Tomioka, Takeshi Shinozaki, Ryuichi Hayashi and Kazuhiro Kaneko
    Citation: BMC Cancer 2016 16:743
    Content type: Research article Published on:

  31. Bicyclol, a novel synthetic antihepatitis drug, is widely known to protect against liver injury. However, few reports have focused on the possible effect of bicyclol on anti-proliferation and autophagy inducti...

    Authors: Yu Wang, Hao Nie, Xin Zhao, Yong Qin and Xingguo Gong
    Citation: BMC Cancer 2016 16:742
    Content type: Research article Published on:

  32. It has become evident that intra-tumor heterogeneity of breast cancer impact on several biological processes such as proliferation, migration, cell death and also might contribute to chemotherapy resistance. T...

    Authors: José Esparza-López, Pier A. Ramos-Elías, Andrea Castro-Sánchez, Leticia Rocha-Zavaleta, Elizabeth Escobar-Arriaga, Alejandro Zentella-Dehesa, Eucario León-Rodríguez, Heriberto Medina-Franco and María de Jesus Ibarra-Sánchez
    Citation: BMC Cancer 2016 16:740
    Content type: Research article Published on:

  34. Efforts to improve end of life care (EoLC) have made tangible impacts on care in adults, including enabling more people to die at their preferred place of death (PoD), usually home or hospices. Little is known...

    Authors: Wei Gao, Julia Verne, Janet Peacock, Charles Stiller, Claudia Wells, Anne Greenough and Irene J. Higginson
    Citation: BMC Cancer 2016 16:727
    Content type: Research article Published on:

  36. The incidence of Papillary thyroid carcinoma (PTC), the most common type of thyroid malignancy, has risen rapidly worldwide. PTC usually has an excellent prognosis. However, the rising incidence of PTC, due at...

    Authors: Kevin Brennan, Christopher Holsinger, Chrysoula Dosiou, John B. Sunwoo, Haruko Akatsu, Robert Haile and Olivier Gevaert
    Citation: BMC Cancer 2016 16:736
    Content type: Research article Published on:

  37. To date, the study of the risks and benefits of breast cancer screening has not included the onset of persistent pain after breast cancer treatment within the context of population-based screening programs. Ou...

    Authors: Anabel Romero, Isabel Torà-Rocamora, Marisa Baré, Teresa Barata, Laia Domingo, Joana Ferrer, Núria Torà, Mercè Comas, Carmen Merenciano, Francesc Macià, Xavier Castells and Maria Sala
    Citation: BMC Cancer 2016 16:735
    Content type: Research article Published on:

  38. In Germany, most breast cancer patients are treated in specialized breast cancer units (BCU), which are certified, and routinely monitored. Herein, we evaluate up-to-date oncological outcome of breast cancer (...

    Authors: André Hennigs, Fabian Riedel, Adam Gondos, Peter Sinn, Peter Schirmacher, Frederik Marmé, Dirk Jäger, Hans-Ulrich Kauczor, Anne Stieber, Katja Lindel, Jürgen Debus, Michael Golatta, Florian Schütz, Christof Sohn, Jörg Heil and Andreas Schneeweiss
    Citation: BMC Cancer 2016 16:734
    Content type: Research article Published on:

  39. Cancer is the leading cause of premature death in Canada. In the last decade, important gains in cancer survival have been achieved by advances in adjuvant treatment. However, many oncologic treatments also re...

    Authors: Edith Pituskin, Mark Haykowsky, Margaret McNeely, John Mackey, Neil Chua and Ian Paterson
    Citation: BMC Cancer 2016 16:733
    Content type: Study protocol Published on:

  40. It is generally accepted that the energy resources of cancer cells rely on anaerobic metabolism or the glycolytic system, even if they have sufficient oxygen. This is known as the Warburg effect. The cells ski...

    Authors: Satomi Ueki, Yuko Murakami, Shoji Yamada, Masaki Kimura, Yoshimasa Saito and Hidetsugu Saito
    Citation: BMC Cancer 2016 16:732
    Content type: Research article Published on:

  41. For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. cruz...

    Authors: Paula Abello-Cáceres, Javier Pizarro-Bauerle, Carlos Rosas, Ismael Maldonado, Lorena Aguilar-Guzmán, Carlos González, Galia Ramírez, Jorge Ferreira and Arturo Ferreira
    Citation: BMC Cancer 2016 16:731
    Content type: Research article Published on:

  42. The purpose of our research was to determine the prognostic impact and clinicopathological feature of c-MYC and β-catenin overexpression in colorectal cancer (CRC) patients.

    Authors: Kyu Sang Lee, Yoonjin Kwak, Kyung Han Nam, Duck-Woo Kim, Sung-Bum Kang, Gheeyoung Choe, Woo Ho Kim and Hye Seung Lee
    Citation: BMC Cancer 2016 16:730
    Content type: Research article Published on:

  43. Lung cancer is usually presented with cough, dyspnea, pain and weight loss, which is overlapping with symptoms of other lung diseases such as pulmonary fibrosis. Pulmonary fibrosis shows characteristic reticul...

    Authors: Bakir Mehić, Lina Duranović Rayan, Nurija Bilalović, Danina Dohranović Tafro and Ilijaz Pilav
    Citation: BMC Cancer 2016 16:729
    Content type: Case report Published on:

  44. Standard therapy for borderline-resectable pancreatic cancer in the UK is surgery with adjuvant chemotherapy, but rates of resection with clear margins are unsatisfactory and overall survival remains poor. Met...

    Authors: Daniel L. P. Holyoake, Elizabeth Ward, Derek Grose, David McIntosh, David Sebag-Montefiore, Ganesh Radhakrishna, Neel Patel, Michael Silva, Somnath Mukherjee, Victoria Y. Strauss, Lang’o Odondi, Emmanouil Fokas, Alan Melcher and Maria A. Hawkins
    Citation: BMC Cancer 2016 16:728
    Content type: Study protocol Published on:

  45. The heterogeneity and tumourigenicity of metastatic melanoma is attributed to a cancer stem cell model, with CD133 considered to be a cancer stem cell marker in melanoma as well as other tumours, but its role ...

    Authors: Carole Grasso, Matthew Anaka, Oliver Hofmann, Ramakrishna Sompallae, Kate Broadley, Winston Hide, Michael V. Berridge, Jonathan Cebon, Andreas Behren and Melanie J. McConnell
    Citation: BMC Cancer 2016 16:726
    Content type: Research article Published on:

  46. Mutations in DNA damage response factors BRCA1 and BRCA2 confer sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors in breast and ovarian cancers. BRCA1/BRCA2-defective tumors can exhibit resistance t...

    Authors: Ruoxi Hong, Fei Ma, Weimin Zhang, Xiying Yu, Qing Li, Yang Luo, Changjun Zhu, Wei Jiang and Binghe Xu
    Citation: BMC Cancer 2016 16:725
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2016 16:925

  47. We previously reported that IL-6 and transglutaminase 2 (TG2) were expressed in more aggressive basal-like breast cancer cells, and TG2 and IL-6 expression gave these cells stem-cell-like phenotypes, increased...

    Authors: Keunhee Oh, Ok-Young Lee, Yeonju Park, Myung Won Seo and Dong-Sup Lee
    Citation: BMC Cancer 2016 16:724
    Content type: Research article Published on:

  48. The primary cause of treatment failure in medulloblastomas (MB) is the development of leptomeningeal dissemination (seeding). For translational research on MB seeding, one of the major challenges is the develo...

    Authors: Seung Ah Choi, Pil Ae Kwak, Seung-Ki Kim, Sung-Hye Park, Ji Yeoun Lee, Kyu-Chang Wang, Hyun Jeong Oh, Kyuwan Kim, Dong Soo Lee, Do Won Hwang and Ji Hoon Phi
    Citation: BMC Cancer 2016 16:723
    Content type: Research article Published on:

  49. Globally, cancer rates are increasing. In Scotland, it is estimated that 2 in 5 people will develop cancer in their lifetime. Therefore, this is crucial time to provide personalised care and support to individ...

    Authors: Austyn Snowden, Jenny Young and Mick Fleming
    Citation: BMC Cancer 2016 16:720
    Content type: Study protocol Published on:

  50. Desmoplastic malignant pleural mesothelioma (DMM) is rare histological subtype of diffuse malignant pleural mesothelioma (MPM), accounting for 5–10 % of cases. It has a poor prognosis, with direct invasion of ...

    Authors: Kana Hashimoto, Yusuke Okuma, Yukio Hosomi and Tsunekazu Hishima
    Citation: BMC Cancer 2016 16:718
    Content type: Case report Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us