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316 result(s) for 'serum psa 29' within BMC Cancer

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  1. Recent preclinical data suggest that androgen receptor (AR) signaling plays a significant role in subsets of breast cancer. Clinical trials testing AR-targeting therapies in breast cancer have been conducted. ...

    Authors: Toru Hanamura, Koichi Ohno, Shinya Hokibara, Hideki Murasawa, Toshitsugu Nakamura, Hidehiko Watanabe, Machiko Kaizuka, Shinji Sawano, Hiroshi Koyama and Ken-ichi Ito
    Citation: BMC Cancer 2019 19:1021
    Content type: Research article Published on:

  2. Serum prostate-specific antigen (PSA) is widely used in screening tests for prostate cancer. As the low specificity of PSA results in unnecessary and invasive prostate biopsies, we evaluated the clinical signi...

    Authors: Jaegeun Lee, Seung Woo Yang, Long Jin, Chung Lyul Lee, Ji Yong Lee, Ju Hyun Shin, Jae Sung Lim and Ki Hak Song
    Citation: BMC Cancer 2021 21:472
    Content type: Research article Published on:

  3. C/EBPα is a transcription factor essential for terminal differentiation of several cell types. It has not known if C/EBPα protein is expressed and functions in the prostate gland.

    Authors: Hong Yin, Hanna S Radomska, Daniel G Tenen and Jonathan Glass
    Citation: BMC Cancer 2006 6:158
    Content type: Research article Published on:

  4. To examine the tumor characteristics, treatments and survival outcomes of prostate cancer (PCa) patients with a prostate-specific antigen (PSA) level < 4 ng/ml.

    Authors: Zhibo Zheng, Zhien Zhou, Weigang Yan, Yi Zhou, Chuyan Chen, Hanzhong Li and Zhigang Ji
    Citation: BMC Cancer 2020 20:340
    Content type: Research article Published on:

  5. There is no consensus on the role of serum dehydroepiandrosterone (DHEA) concentrations in the detection of prostate cancer. This study examined the effectiveness of serum DHEA in predicting candidate patients...

    Authors: Yasuhide Miyoshi, Takashi Kawahara and Hiroji Uemura
    Citation: BMC Cancer 2022 22:1169
    Content type: Research Published on:

  6. To assess the efficacy of salvage radiotherapy (RT) for persistent or rising PSA after radical prostatectomy and to determine prognostic factors identifying patients who may benefit from salvage RT.

    Authors: Laurent Quero, Pierre Mongiat-Artus, Vincent Ravery, Claude Maylin, François Desgrandchamps and Christophe Hennequin
    Citation: BMC Cancer 2008 8:26
    Content type: Research article Published on:

  7. Significant progress in treatment of metastatic castration resistant prostate cancer (mCRPC) has been made. Biomarkers to tailor therapy are scarce. To facilitate decision-making we evaluated dynamic changes o...

    Authors: Phillip Mikah, Laura-Maria Krabbe, Okyaz Eminaga, Edwin Herrmann, Philipp Papavassilis, Reemt Hinkelammert, Axel Semjonow, Andres-Jan Schrader and Martin Boegemann
    Citation: BMC Cancer 2016 16:214
    Content type: Research article Published on:

  8. The magnitude and rapidity of the tumor response to androgen deprivation is known to predict the durability of the therapy. We have investigated the predictive value of categorizing patients by the half-life o...

    Authors: Yong Jin Kang, Won Sik Jang, Jong Kyou Kwon, Cheol Yong Yoon, Joo Yong Lee, Won Sik Ham and Young Deuk Choi
    Citation: BMC Cancer 2017 17:789
    Content type: Research article Published on:

  9. Prostate cancer (PCa) is the second leading cause of cancer deaths in men in the United States. The prostate-specific antigen (PSA), often found at high levels in the serum of PCa patients, has been used as a ...

    Authors: Tracy R Daniels-Wells, Gustavo Helguera, Richard K Leuchter, Rafaela Quintero, Maggie Kozman, José A Rodríguez, Elizabeth Ortiz-Sánchez, Otoniel Martínez-Maza, Birgit C Schultes, Christopher F Nicodemus and Manuel L Penichet
    Citation: BMC Cancer 2013 13:195
    Content type: Research article Published on:

  10. Glioblastoma multiforme (GBM) is the most aggressive and frequent brain tumor, albeit without cure. Although patient survival is limited to one year on average, significant variability in outcome is observed. ...

    Authors: Marie-Claude Amoureux, Béma Coulibaly, Olivier Chinot, Anderson Loundou, Philippe Metellus, Geneviève Rougon and Dominique Figarella-Branger
    Citation: BMC Cancer 2010 10:91
    Content type: Research article Published on:

  11. In patients with bone metastatic castration-resistant prostate cancer (bmCRPC) on systemic treatment, it is difficult to differentiate between continuous rise of prostate specific antigen (PSA) representing pr...

    Authors: Renata Poteska, Kambiz Rahbar, Axel Semjonow, Andres Jan Schrader, Martin Boegemann and Katrin Schlack
    Citation: BMC Cancer 2022 22:375
    Content type: Research Published on:

  12. To determine how much an augmented analysis approach could improve the efficiency of prostate-specific antigen (PSA) response analyses in clinical practice. PSA response rates are commonly used outcome measure...

    Authors: Michael J. Grayling, Martina McMenamin, Robert Chandler, Rakesh Heer and James M. S. Wason
    Citation: BMC Cancer 2022 22:111
    Content type: Research Published on:

  13. In men with a rising PSA following radical prostatectomy, salvage radiation therapy (SRT) offers a second chance for cure. Hormonal therapy can be combined with SRT in order to increase prostate tumor control,...

    Authors: Roche Kapoor, Matthew P. Deek, Riley McIntyre, Natasha Raman, Megan Kummerlowe, Iyah Chen, Matt Gaver, Hao Wang, Sam Denmeade, Tamara Lotan, Channing Paller, Mark Markowski, Michael Carducci, Mario Eisenberger, Tomasz M. Beer, Daniel Y. Song…
    Citation: BMC Cancer 2019 19:572
    Content type: Study protocol Published on:

  14. Serum indicators AFP, CA50, CA125, CA153, CA19-9, CEA, f-PSA, SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide association study on 8 tumor markers of our 427 Han population in sou...

    Authors: Xiukuan Li, Fenghua Bai, Xingwei Wei, Tianbo Jin, Chen Li, Yutian Zhang, Mei Lin, Xiaoli Zhou, Yufei Xie, Chanyi He, Qi Lin, Ping He, Shuyuan Chu and Yipeng Ding
    Citation: BMC Cancer 2022 22:160
    Content type: Research Published on:

  15. Serum selenium level (s-Se) has been associated with prostate cancer (PrCa) risk. We investigated the relation between s-Se, smoking and non-screening detected PrCa and explored if polymorphisms in two DNA rep...

    Authors: Birgitta Grundmark, Björn Zethelius, Hans Garmo and Lars Holmberg
    Citation: BMC Cancer 2011 11:431
    Content type: Research article Published on:

  16. Cancer vaccine is one of the attractive treatment modalities for patients with castration-resistant prostate cancer (CRPC). However, because of delayed immune responses, its clinical benefits, besides for over...

    Authors: Masanori Noguchi, Fukuko Moriya, Shigetaka Suekane, Rei Ohnishi, Satoko Matsueda, Tetsuro Sasada, Akira Yamada and Kyogo Itoh
    Citation: BMC Cancer 2013 13:613
    Content type: Research article Published on:

  17. We hypothesized that pretreatment serum levels of insulin and other serum markers would predict Progression-free survival (PFS), defined as time to castration-resistant progression or death, in metastatic andr...

    Authors: Farshid Dayyani, Amado J. Zurita, Graciela M. Nogueras-González, Rebecca Slack, Randall E. Millikan, John C. Araujo, Gary E. Gallick, Christopher J. Logothetis and Paul G. Corn
    Citation: BMC Cancer 2016 16:721
    Content type: Research article Published on:

  19. There is evidence that derangement in serum electrolytes like sodium and potassium is associated with increased morbidity and mortality among hospitalized critically ill patients, but their role in the context...

    Authors: Arunangshu Ghoshal, Hans Garmo, Niklas Hammar, Ingmar Jungner, Håkan Malmström, Göran Walldius and Mieke Van Hemelrijck
    Citation: BMC Cancer 2018 18:1169
    Content type: Research article Published on:

  20. This study was performed to examine the usefulness of combined androgen blockade (CAB) therapy with a gonadotropin-releasing hormone (GnRH) antagonist (CAB-antagonist therapy), instead of CAB therapy with GnRH...

    Authors: Takeshi Kashiwabara and Sayo Suda
    Citation: BMC Cancer 2018 18:619
    Content type: Research article Published on:

  21. After development of hormone-refractory metastatic disease, prostate cancer is incurable. The recent history of chemotherapy has shown that with difficult disease targets, combinatorial therapy frequently offe...

    Authors: Kristen D Brubaker, Lisha G Brown, Robert L Vessella and Eva Corey
    Citation: BMC Cancer 2006 6:15
    Content type: Research article Published on:

  22. Prostate cancer screening among the general population is highly debatable. Nevertheless, screening among high-risk groups is appealing. Prior data suggests that men carrying mutations in the BRCA1& 2 genes ma...

    Authors: David Margel, Ofer Benjaminov, Rachel Ozalvo, Liat Shavit Grievink, Inbal Kedar, Rinat Yerushalmi, Irit Ben-Aharon, Victoria Neiman, Ofer Yossepowitch, Daniel Kedar, Zohar Levy, Mordechai Shohat, Baruch Brenner, Jack Baniel and Eli Rosenbaum
    Citation: BMC Cancer 2014 14:528
    Content type: Study protocol Published on:

  23. Exosomes or extracellular vesicles have the potential as a diagnostic marker for various diseases including cancer. In order to identify novel exosomal markers for prostate cancer (PC), we performed proteomic ...

    Authors: Kyojiro Kawakami, Yasunori Fujita, Yoko Matsuda, Tomio Arai, Kengo Horie, Koji Kameyama, Taku Kato, Koichi Masunaga, Yutaka Kasuya, Masashi Tanaka, Kosuke Mizutani, Takashi Deguchi and Masafumi Ito
    Citation: BMC Cancer 2017 17:316
    Content type: Research article Published on:

  24. Infection plays a role in the pathogenesis of many human malignancies. Whether prostate cancer (PCa) - an important health issue in the aging male population in the Western world - belongs to these conditions ...

    Authors: Jan Hrbacek, Michael Urban, Eva Hamsikova, Ruth Tachezy, Vaclav Eis, Marek Brabec and Jiri Heracek
    Citation: BMC Cancer 2011 11:53
    Content type: Research article Published on:

  25. Enzalutamide is an oral androgen receptor targeted agent that has been shown to improve survival in PREVAIL trials and has been approved for patients with chemo-naïve metastatic castration-resistant prostate c...

    Authors: Taro Iguchi, Satoshi Tamada, Minoru Kato, Sayaka Yasuda, Takeshi Yamasaki and Tatsuya Nakatani
    Citation: BMC Cancer 2019 19:339
    Content type: Study protocol Published on:

  26. Prostate Cancer (PCa) is the second most frequent neoplasia in men worldwide. Previous reports suggest that the prevalence of PCa in Hispanic males is lower than in Africans (including communities with African...

    Authors: Lauro S Gomez-Guerra, Margarita L Martinez-Fierro, Valeria Alcantara-Aragon, Rocio Ortiz-Lopez, Rebeca T Martinez-Villarreal, Idelma B Morales-Rodriguez, Raquel Garza-Guajardo, Marco A Ponce-Camacho and Augusto Rojas-Martinez
    Citation: BMC Cancer 2009 9:91
    Content type: Research article Published on:

  27. Whilst multi-parametric magnetic resonance imaging (mp-MRI) has been a significant advance in the diagnosis of prostate cancer, scanning all patients with elevated prostate specific antigen (PSA) levels is con...

    Authors: Edward Johnston, Hayley Pye, Elisenda Bonet-Carne, Eleftheria Panagiotaki, Dominic Patel, Myria Galazi, Susan Heavey, Lina Carmona, Alexander Freeman, Giorgia Trevisan, Clare Allen, Alexander Kirkham, Keith Burling, Nicola Stevens, David Hawkes, Mark Emberton…
    Citation: BMC Cancer 2016 16:816
    Content type: Study protocol Published on:

  28. The Wnt inhibitor Dickkopf-1 (DKK-1) has been linked to the progression of malignant bone disease by impairing osteoblast activity. In addition, there is increasing data to suggest direct tumor promoting effec...

    Authors: Tilman D Rachner, Stefanie Thiele, Andy Göbel, Andrew Browne, Susanne Fuessel, Kati Erdmann, Manfred P Wirth, Michael Fröhner, Tilman Todenhöfer, Michael H Muders, Matthias Kieslinger, Martina Rauner and Lorenz C Hofbauer
    Citation: BMC Cancer 2014 14:649
    Content type: Research article Published on:

  29. A substantial number of patients will develop further biochemical progression after radical prostatectomy (RP) and salvage radiotherapy (sRT). Recently published data using prostate-specific membrane antigen l...

    Authors: Ann-Kathrin Oehus, Stephanie G. C. Kroeze, Nina-Sophie Schmidt-Hegemann, Marco M. E. Vogel, Simon Kirste, Jessica Becker, Irene A. Burger, Thorsten Derlin, Peter Bartenstein, Matthias Eiber, Michael Mix, Christian la Fougère, Claus Belka, Stephanie E. Combs, Anca-Ligia Grosu, Arndt-Christian Müller…
    Citation: BMC Cancer 2020 20:362
    Content type: Research article Published on:

  30. Additional accurate non-invasive biomarkers are needed in the clinical setting to improve prostate cancer (PCa) diagnosis. Here we have developed a new and improved multiplex mRNA urine test to detect prostate...

    Authors: Lourdes Mengual, Juan José Lozano, Mercedes Ingelmo-Torres, Laura Izquierdo, Mireia Musquera, María José Ribal and Antonio Alcaraz
    Citation: BMC Cancer 2016 16:76
    Content type: Research article Published on:

  31. The purpose of the present study was to evaluate the prognostic value of POSTN expression following prostatectomy.

    Authors: Pier Vitale Nuzzo, Alessandra Rubagotti, Linda Zinoli, Francesco Ricci, Sandra Salvi, Simona Boccardo and Francesco Boccardo
    Citation: BMC Cancer 2012 12:625
    Content type: Research article Published on:

  32. The objective of this study was to discover and to validate novel noninvasive biomarkers that distinguish between benign prostate hyperplasia (BPH) and localized prostate cancer (PCa), thereby helping to solve...

    Authors: Andrej Jedinak, Adam Curatolo, David Zurakowski, Simon Dillon, Manoj K Bhasin, Towia A Libermann, Roopali Roy, Monisha Sachdev, Kevin R Loughlin and Marsha A Moses
    Citation: BMC Cancer 2015 15:259
    Content type: Research article Published on:

  33. Prostate cancer has a variable clinical behaviour with frequently unpredictable outcome. DNA methylation plays an important role in determining the biology of cancer but prognostic information is scanty. We as...

    Authors: Nataša Vasiljević, Amar S Ahmad, Mangesh A Thorat, Gabrielle Fisher, Daniel M Berney, Henrik Møller, Christopher S Foster, Jack Cuzick and Attila T Lorincz
    Citation: BMC Cancer 2014 14:655
    Content type: Research article Published on:

  34. There is currently no consensus on the correlations between androgen concentrations in prostate tissue and blood and stage and pathological grade of prostate cancer. In this study, we used a newly-developed ul...

    Authors: Yasuhide Miyoshi, Hiroji Uemura, Susumu Umemoto, Kentaro Sakamaki, Satoshi Morita, Kazuhiro Suzuki, Yasuhiro Shibata, Naoya Masumori, Tomohiko Ichikawa, Atsushi Mizokami, Yoshiki Sugimura, Norio Nonomura, Hideki Sakai, Seijiro Honma, Masaoki Harada and Yoshinobu Kubota
    Citation: BMC Cancer 2014 14:717
    Content type: Research article Published on:

  35. Metastasis directed therapy (MDT) for patients with oligometastatic disease is associated with improvements in progression free survival (PFS) and overall survival (OS) compared to systemic therapy alone. Addi...

    Authors: Hamza Hasan, Matthew P. Deek, Ryan Phillips, Robert F. Hobbs, Reem Malek, Noura Radwan, Ana P. Kiess, Shirl Dipasquale, James Huang, Terry Caldwell, Jessica Leitzel, Danielle Wendler, Hao Wang, Elizabeth Thompson, Jonathan Powell, Sara Dudley…
    Citation: BMC Cancer 2020 20:492
    Content type: Study protocol Published on:

  36. The bone scan index (BSI), which is obtained using a computer-aided bone scan evaluation system, is anticipated to become an objective and quantitative clinical tool for evaluating bone metastases in prostate ...

    Authors: Koichi Uemura, Yasuhide Miyoshi, Takashi Kawahara, Shuko Yoneyama, Yusuke Hattori, Jun-ichi Teranishi, Keiichi Kondo, Masatoshi Moriyama, Shigeo Takebayashi, Yumiko Yokomizo, Masahiro Yao, Hiroji Uemura and Kazumi Noguchi
    Citation: BMC Cancer 2016 16:109
    Content type: Research article Published on:

  37. Little is known about the relationship between preoperative body mass index and need for adjuvant radiation therapy (RT) following radical prostatectomy. The goal of this study was to evaluate the utility of b...

    Authors: Kosj Yamoah, Charnita M. Zeigler-Johnson, Abra Jeffers, Bruce Malkowicz, Elaine Spangler, Jong Y. Park, Alice Whittemore and Timothy R. Rebbeck
    Citation: BMC Cancer 2016 16:557
    Content type: Research article Published on:

  38. Durability of androgen-deprivation therapy (ADT) for prostate cancer (PC) is limited. Additional selective estrogen receptor modulators (SERMs) may prolong the durability of ADT, because androgen and estrogen ...

    Authors: Tetsuya Fujimura, Satoru Takahashi, Haruki Kume, Tomohiko Urano, Kenichi Takayama, Yuta Yamada, Motofumi Suzuki, Hiroshi Fukuhara, Tohru Nakagawa, Satoshi Inoue and Yukio Homma
    Citation: BMC Cancer 2015 15:836
    Content type: Research article Published on:

  39. The association of neutrophil-lymphocyte ratio (NLR) and CD34 expression level with PSA level, Gleason score, and clinical stage was investigated in patients with prostate cancer. The correlation between NLR a...

    Authors: Yiyang Wang, Xiaofei Dong, Zhaokui Qu, Kang Peng, Xiaolei Sun and Renfu Chen
    Citation: BMC Cancer 2020 20:900
    Content type: Research article Published on:

  40. The prognostic nutritional index (PNI), an immunity and nutrition based prognostic score, was correlated with clinical outcomes in different tumors. However, the prognostic significance of PNI has not been inv...

    Authors: Bin Li, Zheng Lu, Shengzheng Wang, Junqing Hou, Gang Xia, Heng Li, Bo Yin and Wei Lu
    Citation: BMC Cancer 2020 20:361
    Content type: Research article Published on:

  41. SOX genes play an important role in a number of developmental processes. Potential roles of SOXs have been demonstrated in various neoplastic tissues as tumor suppressors or promoters depending on tumor status...

    Authors: Wei-de Zhong, Guo-qiang Qin, Qi-shan Dai, Zhao-dong Han, Shan-ming Chen, Xiao-hui Ling, Xin Fu, Chao Cai, Jia-hong Chen, Xi-bin Chen, Zhuo-yuan Lin, Ye-han Deng, Shu-lin Wu, Hui-chan He and Chin-lee Wu
    Citation: BMC Cancer 2012 12:248
    Content type: Research article Published on:

  42. The objective of our study was to evaluate the clinical significance of invisible prostate cancer (iPCa) on multiparametric magnetic resonance imaging (mpMRI) by analyzing clinical parameters and oncologic out...

    Authors: Doo Yong Chung, Dong Hoon Koh, Hyeok Jun Goh, Min Seok Kim, Jong Soo Lee, Won Sik Jang and Young Deuk Choi
    Citation: BMC Cancer 2018 18:1057
    Content type: Research article Published on:

  43. To evaluate the safety and efficacy of abiraterone acetate (AA) in the “real life” clinical practice for men with chemotherapy-naïve metastatic castration-resistant prostate.

    Authors: Luca Cindolo, Clara Natoli, Cosimo De Nunzio, Michele De Tursi, Maurizio Valeriani, Silvana Giacinti, Salvatore Micali, Mino Rizzo, Giampaolo Bianchi, Eugenio Martorana, Marcello Scarcia, Giuseppe Mario Ludovico, Pierluigi Bove, Anastasia Laudisi, Oscar Selvaggio, Giuseppe Carrieri…
    Citation: BMC Cancer 2017 17:753
    Content type: Research article Published on:

  44. Several viruses with known oncogenic potential infect prostate tissue, among these are the polyomaviruses BKV, JCV, and SV40; human papillomaviruses (HPVs), and human cytomegalovirus (HCMV) infections. Recentl...

    Authors: Margarita L Martinez-Fierro, Robin J Leach, Lauro S Gomez-Guerra, Raquel Garza-Guajardo, Teresa Johnson-Pais, Joke Beuten, Idelma B Morales-Rodriguez, Mario A Hernandez-Ordoñez, German Calderon-Cardenas, Rocio Ortiz-Lopez, Ana M Rivas-Estilla, Jesus Ancer-Rodriguez and Augusto Rojas-Martinez
    Citation: BMC Cancer 2010 10:326
    Content type: Research article Published on:

  45. The pathological and oncological outcomes of retro-pubic radical prostatectomy (RRP) and robot-assisted radical prostatectomy (RARP) have not been sufficiently investigated.

    Authors: Tetsuya Fujimura, Hiroshi Fukuhara, Satoru Taguchi, Yuta Yamada, Toru Sugihara, Tohru Nakagawa, Aya Niimi, Haruki Kume, Yasuhiko Igawa and Yukio Homma
    Citation: BMC Cancer 2017 17:454
    Content type: Research article Published on:

  46. Ultra-hypofractionated image-guided stereotactic body radiotherapy (SBRT) is increasingly used for definitive treatment of localized prostate cancer. Magnetic resonance imaging-guided radiotherapy (MRgRT) faci...

    Authors: Ariel E. Marciscano, Sydney Wolfe, Xi Kathy Zhou, Christopher E. Barbieri, Silvia C. Formenti, Jim C. Hu, Ana M. Molina, David M. Nanus, Jones T. Nauseef, Douglas S. Scherr, Cora N. Sternberg, Scott T. Tagawa and Himanshu Nagar
    Citation: BMC Cancer 2023 23:781
    Content type: Study Protocol Published on:

  47. Prostate cancer that has recurred after local therapy or disseminated distantly is usually treated with androgen deprivation therapy; however, most men will eventually experience disease progression within 12 ...

    Authors: Eric Winquist, Tricia Waldron, Scott Berry, D Scott Ernst, Sébastien Hotte and Himu Lukka
    Citation: BMC Cancer 2006 6:112
    Content type: Research article Published on:

  49. The proposed trial is to examine the feasibility of prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT)-guided cytoreduction plus apalutamide and androgen depriv...

    Authors: Beihe Wang, Jian Pan, Tingwei Zhang, Xudong Ni, Yu Wei, Xiaomeng Li, Bangwei Fang, Xiaoxin Hu, Hualei Gan, Junlong Wu, Hongkai Wang, Dingwei Ye and Yao Zhu
    Citation: BMC Cancer 2024 24:643
    Content type: Study Protocol Published on:

  50. There is scant data regarding disease presentation and treatment response among black men living in Africa. In this study we evaluate disease presentation and early clinical outcomes among Ghanaian men with pr...

    Authors: Kosj Yamoah, Kwamena Beecham, Sarah E Hegarty, Terry Hyslop, Timothy Showalter and Joel Yarney
    Citation: BMC Cancer 2013 13:23
    Content type: Research article Published on:

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