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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 75 of 79

  1. Neuroblastoma is the most common extracranial solid tumor of childhood. The high rate of recurrence is associated with a low survival rate for patients with high-risk neuroblastoma. There is thus an urgent nee...

    Authors: Yan Su, Lijun Wang, Chiyi Jiang, Zhixia Yue, Hongjun Fan, Huimin Hong, Chao Duan, Mei Jin, Dawei Zhang, Lihua Qiu, Xianfeng Cheng, Zhong Xu and Xiaoli Ma
    Citation: BMC Cancer 2020 20:102
    Content type: Research article Published on:

  2. Esophageal squamous cell carcinoma (ESCC) is one of the most malignant tumors and typically presents at an advanced and rapidly fatal stage. To better understand the role of genetics in the etiology and preven...

    Authors: Nan Hu, Luxia Qian, Ying Hu, Jian-Zhong Shou, Chaoyu Wang, Carol Giffen, Quan-Hong Wang, Yuan Wang, Alisa M Goldstein, Michael Emmert-Buck and Philip R Taylor
    Citation: BMC Cancer 2006 6:33
    Content type: Research article Published on:

  3. Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive forms of malignancies with a nearly equal incidence and mortality rates in patients. Pancreatic stellate cells (PSCs) are critical players ...

    Authors: Shatovisha Dey, Sheng Liu, Tricia D. Factora, Solaema Taleb, Primavera Riverahernandez, Lata Udari, Xiaoling Zhong, Jun Wan and Janaiah Kota
    Citation: BMC Cancer 2020 20:651
    Content type: Research article Published on:

  4. The study was designed to investigate immunocompetence in relation to cancer progression in rat and to assess the effect of the traditional Chinese anti-cancer medicine, "Shenyang" prescription, on immunity.

    Authors: Canhua Jiang, Dongxia Ye, Weiliu Qiu, Xiuli Zhang, Zhiyuan Zhang, Di He, Ping Zhang and Wantao Chen
    Citation: BMC Cancer 2007 7:40
    Content type: Research article Published on:

  5. Epigenetic aberrations and a CpG island methylator phenotype have been shown to be associated with poor outcomes in children with neuroblastoma (NB). Seven cancer related genes (THBS-1, CASP8, HIN-1, TIG-1, BLU, ...

    Authors: Qiwei Yang, Yufeng Tian, Kelly R Ostler, Alexandre Chlenski, Lisa J Guerrero, Helen R Salwen, Lucy A Godley and Susan L Cohn
    Citation: BMC Cancer 2010 10:286
    Content type: Research article Published on:

  6. Hepatocellular carcinoma (HCC) is a major cause of cancer deaths worldwide. However, current chemotherapeutic drugs for HCC are either poorly effective or expensive, and treatment with these drugs has not led ...

    Authors: Yu-Min Feng, Chin-Wen Feng, Syue-Yi Chen, Hsiao-Yen Hsieh, Yu-Hsin Chen and Cheng-Da Hsu
    Citation: BMC Cancer 2015 15:134
    Content type: Research article Published on:

  7. Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver. Non-alcoholic fatty liver disease (NAFLD) is a frequent chronic liver disorder in developed countries. NAFLD can progress through...

    Authors: Alessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Valentina Mastroiaco, Antonella Vetuschi, Roberta Sferra, Remo Barnabei, Daria Capece, Francesca Zazzeroni and Edoardo Alesse
    Citation: BMC Cancer 2016 16:3
    Content type: Research article Published on:

  8. The efficacy of hepatic arterial infusion chemotherapy (HAIC) for advanced hepatocellular carcinoma (HCC) remains unclear. We conducted a multi-center randomized phase II study comparing a sequential HAIC-sora...

    Authors: Masaaki Kondo, Manabu Morimoto, Satoshi Kobayashi, Shinichi Ohkawa, Hisashi Hidaka, Takahide Nakazawa, Hiroshi Aikata, Takeshi Hatanaka, Daichi Takizawa, Kotaro Matsunaga, Chiaki Okuse, Michihiro Suzuki, Masataka Taguri, Takako Ishibashi, Kazushi Numata, Shin Maeda…
    Citation: BMC Cancer 2019 19:954
    Content type: Research article Published on:

  9. Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) – including chronic myeloid leukemia (CML) – and myelodysplastic/myeloproliferative neoplasms (MDS/MPN)...

    Authors: K. A. Mundt, L. D. Dell, P. Boffetta, E. M. Beckett, H. N. Lynch, V. J. Desai, C. K. Lin and W. J. Thompson
    Citation: BMC Cancer 2021 21:227
    Content type: Review Published on:

  10. Previous studies have suggested that lymphoma survivors commonly display altered Health-Related Quality of Life (HRQoL). Because these were predominantly cross-sectional studies, the dynamic of events as well ...

    Authors: Gisèle Compaci, Cécile Conte, Lucie Oberic, Loïc Ysebaert, Guy Laurent and Fabien Despas
    Citation: BMC Cancer 2019 19:1178
    Content type: Research article Published on:

  11. Hepatic metastases occur frequently in the context of many tumor entities. Patients with colorectal carcinoma have already developed liver metastases in 20% at the time of diagnosis, and 25–50% develop metasta...

    Authors: Theresa Voglhuber, Kerstin A. Eitz, Markus Oechsner, Marco M. E. Vogel and Stephanie E. Combs
    Citation: BMC Cancer 2021 21:780
    Content type: Research Published on:

  12. Drug resistance remains a significant challenge in the treatment of pancreatic cancer. The development of drug-resistant cell lines is crucial to understanding the underlying mechanisms of resistance and devel...

    Authors: Cheng Yu, Yuanhui Su, Xin Miao, Changpeng Chai, Huan Tang, Lu Li, Jianfeng Yi, Zhenzhen Ye, Hui Zhang, Zhao Hu, Luyang Chen, Ning Li, Hao Xu and Wence Zhou
    Citation: BMC Cancer 2024 24:800
    Content type: Research Published on:

  13. Several clear cell renal cell carcinoma (ccRCC) cases harbour fibroblast growth factor receptor 4 (FGFR4) gene copy number (CN) gains. In this study, we investigated the functional contribution of FGFR4 CN amplif...

    Authors: Takafumi Narisawa, Sei Naito, Hiromi Ito, Osamu Ichiyanagi, Toshihiko Sakurai, Tomoyuki Kato and Norihiko Tsuchiya
    Citation: BMC Cancer 2023 23:170
    Content type: Research Published on:

  14. This case represents the first report of malignant primary cardiac tumour in a patient with Lynch Syndrome associated with MSH2 pathogenic variant.

    Authors: Pasquale Paolisso, Giulia Saturi, Alberto Foà, Maristella Saponara, Margherita Nannini, Maria Abbondanza Pantaleo, Ornella Leone, Daniela Turchetti, Daniele Calistri, Carlo Savini, Davide Pacini, Carmine Pizzi and Nazzareno Galiè
    Citation: BMC Cancer 2020 20:191
    Content type: Case report Published on:

  15. Benzamide-based radioligands targeting melanin were first developed for imaging melanoma and then for therapeutic purpose with targeted radionuclide therapy (TRT).

    Authors: Emilie Thivat, Jacques Rouanet, Philippe Auzeloux, Nicolas Sas, Elodie Jouberton, Sophie Levesque, Tommy Billoux, Sandrine Mansard, Ioana Molnar, Marion Chanchou, Giovanna Fois, Lydia Maigne, Jean-Michel Chezal, Elisabeth Miot-Noirault, Michel D’Incan, Xavier Durando…
    Citation: BMC Cancer 2022 22:417
    Content type: Study protocol Published on:

  17. Vascular endothelial growth factor (VEGF), tyrosine kinase (TK) and mechanistic target of rapamycin kinase (mTOR) inhibitors are common first-line (1 L) treatments for metastatic renal cell carcinoma (mRCC). D...

    Authors: Sumanta Pal, Jun Gong, Shivani K. Mhatre, Shih-Wen Lin, Andy Surinach, Sarika Ogale, Rini Vohra, Herschel Wallen and Daniel George
    Citation: BMC Cancer 2019 19:548
    Content type: Research article Published on:

  18. Transcription factor Snail1 has a central role in induction of epithelial-mesenchymal transition (EMT). The aim of the present study was to elucidate the expression of Snail1 protein during epithelial ovarian ...

    Authors: Hanna Tuhkanen, Ylermi Soini, Veli-Matti Kosma, Maarit Anttila, Reijo Sironen, Kirsi Hämäläinen, Laura Kukkonen, Ismo Virtanen and Arto Mannermaa
    Citation: BMC Cancer 2009 9:289
    Content type: Research article Published on:

  20. Urothelial carcinoma (UC) is the ninth most commonly diagnosed cancer worldwide, with a 3.8/1 male to female ratio. Platinum-based chemotherapy is the first line standard of care for fit patients with advanced...

    Authors: Elodie Coquan, Bénédicte Clarisse, Justine Lequesne, Pierre-Emmanuel Brachet, Zoé Nevière, Emeline Meriaux, Isabelle Bonnet, Marie Castera, Nicolas Goardon, Jeremy Boutrois, Romain Travers, Florence Joly, Jean-Michel Grellard and Antoine Thiery-Vuillemin
    Citation: BMC Cancer 2022 22:1213
    Content type: Study protocol Published on:

  21. In randomized controlled trials (RCTs) of adjuvant treatment for malignant tumors, event-free survival (EFS) is considered the most acceptable surrogate for overall survival (OS). However, even though EFS has ...

    Authors: Kazuhiro Tanaka, Masanori Kawano, Tatsuya Iwasaki, Ichiro Itonaga and Hiroshi Tsumura
    Citation: BMC Cancer 2020 20:379
    Content type: Research article Published on:

  22. Recommending the optimal treatment for an individual patient requires a well-balanced consideration of various medical, social and ethical factors. The interplay of these factors, interpretation of the patient...

    Authors: I. Otte, S. Salloch, A. Reinacher-Schick and J. Vollmann
    Citation: BMC Cancer 2017 17:780
    Content type: Research article Published on:

  23. Expression of caveolin-1 (Cav-1) is frequently altered in many human cancers and both tumor suppression and promotion functions of Cav-1 have been suggested based on its expression status. However, it remains ...

    Authors: Byung-Kyu Ryu, Min-Goo Lee, Nam-Hoon Kim, Kil Yeon Lee, Shin-Ju Oh, Jung-Rock Moon, Hyo Jong Kim and Sung-Gil Chi
    Citation: BMC Cancer 2017 17:766
    Content type: Research article Published on:

  25. Epigenetic mechanisms such as DNA methylation and histone modifications are important regulators of gene expression and are frequently involved in silencing tumor suppressor genes.

    Authors: Helena Carén, Anna Djos, Maria Nethander, Rose-Marie Sjöberg, Per Kogner, Camilla Enström, Staffan Nilsson and Tommy Martinsson
    Citation: BMC Cancer 2011 11:66
    Content type: Research article Published on:

  26. Syndecan-1 (SDC-1) is a crucial membrane proteoglycan, which is confirmed to participate in several tumor cell biological processes. However, the biological significance of SDC-1 in colorectal carcinoma is not...

    Authors: Shaojun Wang, Xiaofei Zhang, Guimei Wang, Bin Cao, Hong Yang, Lipeng Jin, Mingjuan Cui and Yongjun Mao
    Citation: BMC Cancer 2019 19:1160
    Content type: Research article Published on:

  27. Osteosarcoma (OS) is well-known for poor prognosis due to its high incidence of proliferation and metastasis. Researches have provided valuable insights into the tumorigenesis of S100A9 in some cancers. We aim...

    Authors: Si Cheng, Xi Zhang, Ning Huang, Quanhe Qiu, Ying Jin and Dianming Jiang
    Citation: BMC Cancer 2016 16:253
    Content type: Research article Published on:

  28. Spatial inequalities in cancer management have been evidenced by studies reporting lower quality of care or/and lower survival for patients living in remote or socially deprived areas. NETSARC+ is a national r...

    Authors: Yohan Fayet, Raphaël Tétreau, Charles Honoré, Louis-Romée Le Nail, Cécile Dalban, François Gouin, Sylvain Causeret, Sophie Piperno-Neumann, Simone Mathoulin-Pelissier, Marie Karanian, Antoine Italiano, Loïc Chaigneau, Justine Gantzer, François Bertucci, Mickael Ropars, Esma Saada-Bouzid…
    Citation: BMC Cancer 2021 21:631
    Content type: Research Published on:

  30. Immunotherapy or apatinib alone has been used as third-line adjuvant therapy for advanced or metastatic gastric/gastroesophageal junction (G/GEJ) tumors, but the efficacy of combining them with each other for ...

    Authors: Jincheng Wang, Jie Lin, Ruimin Wang, Ti Tong and Yinghao Zhao
    Citation: BMC Cancer 2024 24:603
    Content type: Systematic Review Published on:

  31. To compare pain response outcomes for patients with spinal bone metastases treated with resistance training of the spinal musculature versus passive physical therapy during radiotherapy (RT).

    Authors: Harald Rief, Thomas Welzel, Georg Omlor, Michael Akbar, Thomas Bruckner, Stefan Rieken, Matthias F Haefner, Ingmar Schlampp, Alexandros Gioules and Jürgen Debus
    Citation: BMC Cancer 2014 14:485
    Content type: Research article Published on:

  32. Metastasis to the pituitary gland is extremely rare and is often detected incidentally by symptoms associated with endocrine dysfunction. Breast and lung cancer are the most common primary metastasizing to pit...

    Authors: Tomoko Tanaka, Katsushi Hiramatsu, Takuto Nosaka, Yasushi Saito, Tatsushi Naito, Kazuto Takahashi, Kazuya Ofuji, Hidetaka Matsuda, Masahiro Ohtani, Tomoyuki Nemoto, Hiroyuki Suto, Tatsuya Yamamoto, Hirohiko Kimura and Yasunari Nakamoto
    Citation: BMC Cancer 2015 15:863
    Content type: Case report Published on:

  33. Primary cardiac angiosarcomas are rare, but they are the most aggressive type of primary cardiac neoplasms. When patients do present, it is with advanced pulmonary and/or cardiac symptoms. Therefore, many time...

    Authors: Leah Zhrebker, Irene Cherni, Lara M. Gross, Margaret M. Hinshelwood, Merrick Reese, Jessica Aldrich, Joseph M. Guileyardo, William C. Roberts, David Craig, Daniel D. Von Hoff, Robert G. Mennel and John D. Carpten
    Citation: BMC Cancer 2017 17:17
    Content type: Case report Published on:

  34. Neuroblastoma (NB), a tumor of the primitive neural crest, despite aggressive treatment portends a poor long-term survival for patients with advanced high stage NB. New treatment strategies are required.

    Authors: Reza Bayat Mokhtari, Narges Baluch, Micky Ka Hon Tsui, Sushil Kumar, Tina S. Homayouni, Karen Aitken, Bikul Das, Sylvain Baruchel and Herman Yeger
    Citation: BMC Cancer 2017 17:156
    Content type: Research article Published on:

  35. Prediction of the outcome of sorafenib therapy using biomarkers is an unmet clinical need in patients with advanced hepatocellular carcinoma (HCC). The aim was to develop and validate a biomarker-based model f...

    Authors: Hwi Young Kim, Dong Hyeon Lee, Jeong-Hoon Lee, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim and Jung-Hwan Yoon
    Citation: BMC Cancer 2018 18:307
    Content type: Research article Published on:

  36. Median OS after surgery in curative intent for non-metastasized pancreas cancer ranges under study conditions from 17.9 months to 23.6 months. Tumor recurrence occurs locally, at distant sites (liver, peritone...

    Authors: Michael Tachezy, Florian Gebauer, Cordula Petersen, Dirk Arnold, Martin Trepel, Karl Wegscheider, Phillipe Schafhausen, Maximilian Bockhorn, Jakob Robert Izbicki and Emre Yekebas
    Citation: BMC Cancer 2014 14:411
    Content type: Study protocol Published on:

  37. Haemophagocytic lymphohistiocytosis (HLH) is considered to be a large challenge for clinicians due to the variable overlaps of symptoms with other severe diseases and a high rate of mortality. Prompt diagnosis...

    Authors: Fei Li, Xiaojie Zhang, Yunyun Wang, Ailin Yang, Zhanglin Zhang, Weiping Tang, Nan Zhong and Huidong Shi
    Citation: BMC Cancer 2018 18:604
    Content type: Case report Published on:

  39. Fragile sites are regions of the genome sensitive to replication stress and to exposure to environmental carcinogens. The two most commonly expressed fragile sites FRA3B and FRA16D host the histidine triad (FHIT)...

    Authors: Pascale Willem, Jacqueline Brown and Jan Schouten
    Citation: BMC Cancer 2006 6:205
    Content type: Technical advance Published on:

  40. Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcription factor that belongs to the nuclear hormone receptor superfamily. PPARγ is essential in adipocyte differentiation fro...

    Authors: Akihiko Takeuchi, Norio Yamamoto, Toshiharu Shirai, Katsuhiro Hayashi, Shinji Miwa, Seiichi Munesue, Yasuhiko Yamamoto and Hiroyuki Tsuchiya
    Citation: BMC Cancer 2016 16:442
    Content type: Research article Published on:

  41. Detecting superficial head and neck squamous cell carcinoma (HNSCC) by endoscopy is challenging because of limited morphological hallmarks, and iodine cannot be applied to head and neck lesions due to severe m...

    Authors: Takeshi Mizushima, Shunsuke Ohnishi, Yuichi Shimizu, Yutaka Hatanaka, Kanako C. Hatanaka, Hidetaka Hosono, Yoshimasa Kubota, Mitsuteru Natsuizaka, Mako Kamiya, Shouko Ono, Akihiro Homma, Mototsugu Kato, Naoya Sakamoto and Yasuteru Urano
    Citation: BMC Cancer 2016 16:411
    Content type: Research article Published on:

  42. CD13 (APN) is an Alanyl-Aminopeptidase with diverse functions. The role of CD13 for gliomas is still unknown. In this study, data of glioma patients obtained by TCGA and CGGA databases were used to evaluate th...

    Authors: Wenying Zhang, Anne Blank, Irina Kremenetskaia, Anja Nitzsche, Güliz Acker, Peter Vajkoczy and Susan Brandenburg
    Citation: BMC Cancer 2024 24:369
    Content type: Research Published on:

  43. Chemotherapy may improve survival in patients undergoing resection of colorectal liver metastases (CLM). Neoadjuvant chemotherapy may help identify patients with occult extrahepatic disease (averting unnecessa...

    Authors: Oliver F Bathe, Scott Ernst, Francis R Sutherland, Elijah Dixon, Charles Butts, David Bigam, David Holland, Geoffrey A Porter, Jennifer Koppel and Scot Dowden
    Citation: BMC Cancer 2009 9:156
    Content type: Research article Published on:

  44. Systemic inflammatory parameters are associated with poor outcomes in malignant patients. Several inflammation-based cumulative prognostic score systems were established for various solid tumors. However, ther...

    Authors: Feifei Sun, Jia Zhu, Suying Lu, Zijun Zhen, Juan Wang, Junting Huang, Zonghui Ding, Musheng Zeng and Xiaofei Sun
    Citation: BMC Cancer 2018 18:5
    Content type: Research article Published on:

  45. Circulating plasma Epstein Barr Virus DNA (EBV-DNA) is a sensitive and specific marker of nasopharyngeal carcinoma (NPC). The mainstay of treatment of metastatic NPC is systemic chemotherapy and resection for ...

    Authors: Stephen L Chan, Edwin P Hui, Sing F Leung, Anthony TC Chan and Brigette BY Ma
    Citation: BMC Cancer 2006 6:259
    Content type: Case report Published on:

  46. Little is known about the clinical features and prognostic factors of bone metastases of hepatocellular carcinoma (HCC) following liver transplantation (LT).

    Authors: Jian He, Zhao-Chong Zeng, Jia Fan, Jian Zhou, Jing Sun, Bing Chen, Ping Yang, Bin-Liang Wang, Bo-Heng Zhang and Jian-Ying Zhang
    Citation: BMC Cancer 2011 11:492
    Content type: Research article Published on:

  47. The partitioned survival model (PSM) and the state transition model (STM) are widely used in cost-effectiveness analyses of anticancer drugs. Using different modeling approaches with or without consideration o...

    Authors: Yoon-Bo Shim, Byeong-Chan Oh, Eui-Kyung Lee and Mi-Hai Park
    Citation: BMC Cancer 2024 24:189
    Content type: Research Published on:

  48. Long-term term survival in patients with pancreatic neuroendocrine tumors has been reported, even in patients with metastatic disease. Metastases to the spleen are extremely rare, but have been reported from a...

    Authors: Yasunaru Sakuma, Yoshikazu Yasuda, Naohiro Sata, Yoshinori Hosoya, Atsushi Shimizu, Hirofumi Fujii, Daisuke Matsubara, Noriyuki Fukushima, Atsushi Miki, Misato Maeno and Alan Kawarai Lefor
    Citation: BMC Cancer 2017 17:37
    Content type: Case report Published on:

  49. In the absence of head-to-head trials comparing axitinib with cabozantinib or everolimus, the aim of this study was to conduct an indirect comparison of their relative efficacy in patients with metastatic rena...

    Authors: Irina Proskorovsky, Agnes Benedict, Sylvie Negrier, Danielle Bargo, Rickard Sandin, Krishnan Ramaswamy, Jigar Desai, Joseph C. Cappelleri and James Larkin
    Citation: BMC Cancer 2018 18:1271
    Content type: Research article Published on:

  50. Osteosarcoma is a very aggressive tumor with a propensity to metastasize and invade surrounding tissue. Identification of the molecular determinants of invasion and metastatic potential may guide the developme...

    Authors: Cristiane A Dalla-Torre, Maisa Yoshimoto, Chung-Hae Lee, Anthony M Joshua, Silvia RC de Toledo, Antônio S Petrilli, Joyce AD Andrade, Susan Chilton-MacNeill, Maria Zielenska and Jeremy A Squire
    Citation: BMC Cancer 2006 6:237
    Content type: Research article Published on:

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