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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. CXC chemokine ligand 3 (CXCL3) is a member of CXC-type chemokine family that is identified as a major regulator in immune and inflammation responses. Recently, numerous evidence indicated that CXCL3 is broadly...

    Authors: Yao Cheng, Xinyan Yang, Lichun Liang, Hua Xin, Xinyu Dong, Weidong Li, Jie Li, Xiaoli Guo, Yue Li, Jian He, Chunbin Zhang and Weiqun Wang
    Citation: BMC Cancer 2023 23:1162
    Content type: Research Published on:

  2. Cancer immunotherapy with immune checkpoint blockade (CKB) is now standard of care for multiple cancers. The clinical response to CKB is associated with T cell immunity targeting cancer-induced mutations that ...

    Authors: Pooja Narang, Meixuan Chen, Amit A. Sharma, Karen S. Anderson and Melissa A. Wilson
    Citation: BMC Cancer 2019 19:200
    Content type: Research article Published on:

  3. Glioblastoma multiforme (GBM) is one of the most malignant tumors in brain with high morbidity and mortality. Mitophagy plays a significant role in carcinogenesis, metastasis, and invasion. In our study, we ai...

    Authors: Jinghua Wang, Xinqi Qiu, Jiayu Huang, Zewei Zhuo, Hao Chen, Ruijie Zeng, Huihuan Wu, Kehang Guo, Qi Yang, Huiling Ye, Wei Huang and Yujun Luo
    Citation: BMC Cancer 2022 22:644
    Content type: Research Published on:

  4. Due to the ageing population and improving diagnostics and treatments, the number of cancer patients and cancer survivors is increasing. Policymakers, patients and professionals advocate a transfer of (part of...

    Authors: I. A. A. Perfors, C. W. Helsper, E. A. Noteboom, E. van der Wall, N. J. de Wit and A. M. May
    Citation: BMC Cancer 2018 18:132
    Content type: Study protocol Published on:

  6. Thymidine kinase 1 (TK1) is a proliferation biomarker that has been found useful for prognostication in cancer patients. Here we investigate for the first time the use of TK1 expression as a prognostic factor ...

    Authors: Gang Chen, Cheng He, Ling Li, An Lin, Xiongwei Zheng, Ellen He and Sven Skog
    Citation: BMC Cancer 2013 13:249
    Content type: Research article Published on:

  7. It is very important to accurately delineate the CTV on the patient’s three-dimensional CT image in the radiotherapy process. Limited to the scarcity of clinical samples and the difficulty of automatic delinea...

    Authors: Zhongjian Ju, Wen Guo, Shanshan Gu, Jin Zhou, Wei Yang, Xiaohu Cong, Xiangkun Dai, Hong Quan, Jie Liu, Baolin Qu and Guocai Liu
    Citation: BMC Cancer 2021 21:243
    Content type: Research article Published on:

  8. Triple-negative breast cancer (TNBC) is a life-threatening subtype of breast cancer with limited treatment options. Therefore, this network meta-analysis (NMA) aimed to evaluate and compare the effect of vario...

    Authors: Zhilin Liu, Jinming Li, Fuxing Zhao, Dengfeng Ren, Zitao Li, Yongzhi Chen, Shifen Huang, Zhen Liu, Yi Zhao, Miaozhou Wang, Huihui Li, ZhengBo Xu, Guoshuang Shen and Jiuda Zhao
    Citation: BMC Cancer 2024 24:440
    Content type: Research Published on:

  9. Myoepithelial carcinoma (MEC) is a rare salivary gland tumor. Its long-term prognosis remains unknown because of the paucity of reported cases with long-term follow-up. Although some case series exist, the cli...

    Authors: Takahiro Wakasaki, Marie Kubota, Yutaka Nakashima, Eri Tomonobe, Takenao Mihara and Junichi Fukushima
    Citation: BMC Cancer 2016 16:827
    Content type: Case report Published on:

  10. In clinical practice, the detection of biomarkers is mostly based on primary tumors for its convenience in acquisition. However, immune checkpoints may express differently between primary and metastatic tumor....

    Authors: Xingming Zhang, Xiaoxue Yin, Haoran Zhang, Guangxi Sun, Yaojing Yang, Junru Chen, Xudong Zhu, Peng Zhao, Jinge Zhao, Jiandong Liu, Ni Chen, Jia Wang, Pengfei Shen and Hao Zeng
    Citation: BMC Cancer 2019 19:360
    Content type: Research article Published on:

  11. The pretreatment albumin to globulin ratio (AGR) has been reported to correlate with the long-term survival in patients with various cancers. However, there are no reports regarding the correlation between the...

    Authors: Masatsune Shibutani, Kiyoshi Maeda, Hisashi Nagahara, Hiroshi Ohtani, Yasuhito Iseki, Tetsuro Ikeya, Kenji Sugano and Kosei Hirakawa
    Citation: BMC Cancer 2015 15:347
    Content type: Research article Published on:

  12. Sialyl Lewis x (sLex) antigen is a carbohydrate antigen that is considered not only a marker for cancer but also implicated functionally in the malignant behaviour of cancer cells. Overexpression of sLex is assoc...

    Authors: Salomé S Pinho, Augusto JF Matos, Célia Lopes, Nuno T Marcos, Júlio Carvalheira, Celso A Reis and Fátima Gärtner
    Citation: BMC Cancer 2007 7:124
    Content type: Research article Published on:

  13. Multiple trials have attempted to assess the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in osteosarcoma with results remaining inconclusive. This ...

    Authors: Fanxiao Liu, Qingyu Zhang, Dongsheng Zhou and Jinlei Dong
    Citation: BMC Cancer 2019 19:323
    Content type: Research article Published on:

  14. After initial treatment of differentiated thyroid carcinoma (DTC) patients are followed with thyroglobulin (Tg) measurements to detect recurrences. In case of elevated levels of Tg and negative neck ultrasonog...

    Authors: Jakob W Kist, Bart de Keizer, Marcel PM Stokkel, Otto S Hoekstra and Wouter V Vogel
    Citation: BMC Cancer 2014 14:405
    Content type: Study protocol Published on:

  15. Bronchial carcinoids are pulmonary neuroendocrine cell-derived tumors comprising typical (TC) and atypical (AC) malignant phenotypes. The 5-year survival rate in metastatic carcinoid, despite multiple current ...

    Authors: Reza Bayat Mokhtari, Sushil Kumar, Syed S Islam, Mehrdad Yazdanpanah, Khosrow Adeli, Ernest Cutz and Herman Yeger
    Citation: BMC Cancer 2013 13:378
    Content type: Research article Published on:

  16. The specific differentiation potential, unlimited proliferation, and self-renewal capacity of cancer stem cells (CSCs) are closely related to the occurrence, recurrence, and drug resistance of hepatocellular c...

    Authors: Genhao Zhang, Kai Zhang, Yanteng Zhao, Qiankun Yang and Xianping Lv
    Citation: BMC Cancer 2022 22:1103
    Content type: Research Published on:

  17. Fibrinogen (FIB) is an important source of fibrin, which plays a crucial role in circulating tumor cells (CTCs) extravasation and distant metastasis development. We hypothesize it’s stable final product, plasm...

    Authors: Dongmei Diao, Yao Cheng, Yongchun Song, Hao Zhang, Zhangjian Zhou and Chengxue Dang
    Citation: BMC Cancer 2017 17:56
    Content type: Research article Published on:

  18. TMPRSS2-ERG gene rearrangement, the most common E26 transformation specific (ETS) gene fusion within prostate cancer, is known to contribute to the pathogenesis of this disease and carries diagnostic annotations ...

    Authors: Vipulkumar Dadhania, Daniel Gonzalez, Mustafa Yousif, Jerome Cheng, Todd M. Morgan, Daniel E. Spratt, Zachery R. Reichert, Rahul Mannan, Xiaoming Wang, Anya Chinnaiyan, Xuhong Cao, Saravana M. Dhanasekaran, Arul M. Chinnaiyan, Liron Pantanowitz and Rohit Mehra
    Citation: BMC Cancer 2022 22:494
    Content type: Research article Published on:

  19. Sarcomas is a group of heterogeneous malignant tumors originated from mesenchymal tissue and different types of sarcomas have disparate outcomes. The present study aims to identify the prognostic value of immu...

    Authors: Rui Shen, Bo Liu, Xuesen Li, Tengbo Yu, Kuishuai Xu and Jinfeng Ma
    Citation: BMC Cancer 2021 21:144
    Content type: Research article Published on:

  20. Small GTP binding protein Rac1 is a component of NADPH oxidases and is essential for superoxide-induced cell death. Rac1 is activated by guanine nucleotide exchange factors (GEFs), and this activation can be b...

    Authors: Nan Wu, Dong Ren, Su Li, Wenli Ma, Shaoyan Hu, Yan Jin and Sheng Xiao
    Citation: BMC Cancer 2018 18:67
    Content type: Research article Published on:

  21. Nasopharyngeal carcinoma (NPC) is prevalent in South East Asia and Southern China particularly, despite the reported 5-year survival ratio is relative higher than other deadly cancers such as liver, renal, pan...

    Authors: Man Niu, Dan Gao, Qiuyuan Wen, Pingpin Wei, Suming Pan, Cijun Shuai, Huiling Ma, Juanjuan Xiang, Zheng Li, Songqing Fan, Guiyuan Li and Shuping Peng
    Citation: BMC Cancer 2016 16:218
    Content type: Research article Published on:

  22. Tryptophan 2,3-dioxygenase (TDO2) is the primary enzyme catabolizing tryptophan. Several lines of evidence revealed that overexpression of TDO2 is involved in anoikis resistance, spheroid formation, proliferat...

    Authors: Quoc Thang Pham, Daiki Taniyama, Yohei Sekino, Shintaro Akabane, Takashi Babasaki, Go Kobayashi, Naoya Sakamoto, Kazuhiro Sentani, Naohide Oue and Wataru Yasui
    Citation: BMC Cancer 2021 21:737
    Content type: Research Published on:

  23. There is no consensus on the indication for salvage chemoradiotherapy (CRT) after failure of primary chemotherapy for locally advanced pancreatic cancer (LAPC). Here we report on the retrospective analysis of ...

    Authors: Hiroshi Mayahara, Yoshinori Ito, Chigusa Morizane, Hideki Ueno, Takuji Okusaka, Shunsuke Kondo, Naoya Murakami, Madoka Morota, Minako Sumi and Jun Itami
    Citation: BMC Cancer 2012 12:609
    Content type: Research article Published on:

  24. Some historic breakthroughs have been made in immunotherapy of advanced cancer. However, there is still little research on immunotherapy in prostate cancer. We explored the relationship between immune cell inf...

    Authors: Xin Rui, Siliang Shao, Li Wang and Jiangyong Leng
    Citation: BMC Cancer 2019 19:1179
    Content type: Research article Published on:

  25. Various molecular-targeting therapies have become available for the treatment of advanced renal cell carcinoma (RCC). Accurate prognostication is desirable for choosing the appropriate treatment for individual...

    Authors: Noboru Nakaigawa, Keiichi Kondo, Ukihide Tateishi, Ryogo Minamimoto, Tomohiro Kaneta, Kazuhiro Namura, Daiki Ueno, Kazuki Kobayashi, Takeshi Kishida, Ichiro Ikeda, Hisashi Hasumi, Kazuhide Makiyama, Yoshinobu Kubota, Tomio Inoue and Masahiro Yao
    Citation: BMC Cancer 2016 16:67
    Content type: Research article Published on:

  26. Tyrosine kinase inhibitors (TKIs) have become the mainstay of treatment for advanced renal cell carcinoma (RCC), but it has been unclear whether the antitumor effect of TKIs depends on the organ where the RCC ...

    Authors: Manabu Kakizoe, Masahiro Yao, Ukihide Tateishi, Ryogo Minamimoto, Daiki Ueno, Kazuhiro Namura, Kazuhide Makiyama, Narihiko Hayashi, Futoshi Sano, Takeshi Kishida, Kazuki Kobayashi, Sumio Noguchi, Ichiro Ikeda, Yoshiharu Ohgo, Masataka Taguri, Satoshi Morita…
    Citation: BMC Cancer 2014 14:390
    Content type: Research article Published on:

  27. Cardiac Myxoma is a primary tumor of heart. Its origins, rarity of the occurrence of primary cardiac tumors and how it may be related to limited cardiac regenerative potential, are not yet entirely known. This...

    Authors: Ovais Shafi, Ghazia Siddiqui and Hassam A. Jaffry
    Citation: BMC Cancer 2023 23:1245
    Content type: Research Published on:

  28. Nasopharyngeal carcinoma (NPC) is a malignancy predominantly associated with infection by the Epstein-Barr virus (EBV). Approximately 12,900 new cases of NPC occur each year, with more than 70% of cases occurr...

    Authors: Jin-Hao Yang, Xue-Song Sun, Bei-Bei Xiao, Li-Ting Liu, Shan-Shan Guo, Jia-Dong Liang, Guo-Dong Jia, Lin-Quan Tang, Qiu-Yan Chen and Hai-Qiang Mai
    Citation: BMC Cancer 2021 21:534
    Content type: Research Published on:

  29. In recent years, the differences between left-sided colon cancer (LCC) and right-sided colon cancer (RCC) have received increasing attention due to the clinicopathological variation between them. However, some...

    Authors: Yimei Jiang, Xiaowei Yan, Kun Liu, Yiqing Shi, Changgang Wang, Jiele Hu, You Li, Qinghua Wu, Ming Xiang and Ren Zhao
    Citation: BMC Cancer 2020 20:1012
    Content type: Research article Published on:

  31. Occult invasive cervical cancer (OICC) is sometimes incidentally found in surgical specimens after a simple hysterectomy (SH). This study was aimed at identifying a subset of patients with OICC who have a favo...

    Authors: Huimin Bai, Dongyan Cao, Fang Yuan, Huilan Wang, Jie Chen, Yue Wang, Keng Shen and Zhenyu Zhang
    Citation: BMC Cancer 2016 16:507
    Content type: Research article Published on:

  32. Invasive pancreatic neoplasms have a high propensity for recurrence even after curative resection. Recently, patients who underwent pancreatectomy have an opportunity of undergoing secondary pancreatic resecti...

    Authors: Shigetsugu Takano, Hideyuki Yoshitomi, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Takashi Mishima, Eri Nakadai, Masaru Miyazaki and Masayuki Ohtsuka
    Citation: BMC Cancer 2020 20:111
    Content type: Research article Published on:

  33. The WW domain containing protein WWOX has been postulated to behave as a tumor suppressor in breast and other cancers. Expression of this protein is lost in over 70% of ER negative tumors. This prompted us to ...

    Authors: Brent W Ferguson, Xinsheng Gao, Maciej J Zelazowski, Jaeho Lee, Collene R Jeter, Martin C Abba and C Marcelo Aldaz
    Citation: BMC Cancer 2013 13:593
    Content type: Research article Published on:

  34. Cancer development is strictly correlated to composition and physical properties of the extracellular matrix. Particularly, a higher matrix stiffness has been demonstrated to promote tumor sustained growth. Ou...

    Authors: Changsong Wang, Xiaozhong Jiang, Bin Huang, Wenhao Zhou, Xiao Cui, Chenghong Zheng, Fenghao Liu, Jieling Bi, Yi Zhang, Hong Luo, Lin Yuan, Jianyong Yang and Yu Yu
    Citation: BMC Cancer 2021 21:1276
    Content type: Research Published on:

  35. Advances in high-throughput technologies and bioinformatics have transformed gene expression profiling methodologies. The results of microarray experiments are often validated using reverse transcription quant...

    Authors: Kah Hoong Chang, Pieter Mestdagh, Jo Vandesompele, Michael J Kerin and Nicola Miller
    Citation: BMC Cancer 2010 10:173
    Content type: Research article Published on:

  36. To evaluate the prognostic significance of the pre-operative C-reactive protein (CRP) serum level in patients with renal cell cancer (RCC).

    Authors: Sandra Steffens, Astrid Köhler, Raphael Rudolph, Hendrik Eggers, Christoph Seidel, Martin Janssen, Gerd Wegener, Mark Schrader, Markus A Kuczyk and Andres J Schrader
    Citation: BMC Cancer 2012 12:399
    Content type: Research article Published on:

  37. For decades, retinoids and their synthetic derivatives have been well established anticancer treatments due to their ability to regulate cell growth and induce cell differentiation and apoptosis. Many studies ...

    Authors: Viera Dobrotkova, Petr Chlapek, Pavel Mazanek, Jaroslav Sterba and Renata Veselska
    Citation: BMC Cancer 2018 18:1059
    Content type: Review Published on:

  38. This study aimed to evaluate the prognostic value of maximal standard uptake values (SUVmax) of 18F-fluoro-2-deoxy-D-glucose positron emission tomography (PET) comparing with Epstein-Barr virus (EBV) DNA levels i...

    Authors: Xue-Song Sun, Yu-Jing Liang, Sai-Lan Liu, Qiu-Yan Chen, Shan-Shan Guo, Yue-Feng Wen, Li-Ting Liu, Hao-Jun Xie, Qing-Nan Tang, Xiao-Yun Li, Jin-Jie Yan, Lin-Quan Tang and Hai-Qiang Mai
    Citation: BMC Cancer 2019 19:908
    Content type: Research article Published on:

  39. We have developed a new diagnostic method using the photosensitizer 5-aminolevulinic acid (5ALA) for diagnosing intrathoracic malignant lesions. When ingested exogenously, 5ALA is metabolized to a heme precurs...

    Authors: Masahiro Kitada, Yoshinobu Ohsaki, Yoshinari Matsuda, Satoshi Hayashi and Kei Ishibashi
    Citation: BMC Cancer 2015 15:174
    Content type: Research Published on:

  40. The incidence of meningeal carcinomatosis appears to be higher than in the past due to advances in neuro-imaging diagnostic techniques and improvements in cancer survival. Among solid tumors, breast cancer is ...

    Authors: Gloria Mittica, Rebecca Senetta, Lorenzo Richiardi, Roberta Rudà, Renato Coda, Isabella Castellano, Anna Sapino and Paola Cassoni
    Citation: BMC Cancer 2015 15:1021
    Content type: Research article Published on:

  41. Nutritional impact symptoms (NISs) are proposed to be a key indicator of decreased dietary intake in patients with solid cancer. Cancer patients frequently experience NIS from the disease itself and from disea...

    Authors: Muna H. Shakhshir, Husam T. Salameh, Riad Amer and Sa’ed H. Zyoud
    Citation: BMC Cancer 2024 24:524
    Content type: Research Published on:

  42. ESR1 mutations have attracted attention as a potentially important marker and treatment target in endocrine therapy-resistant breast cancer patients. The E380Q mutation, which is one o...

    Authors: Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Aiko Sueta, Mai Tomiguchi, Keiichi Murakami, Yoko Omoto and Hirotaka Iwase
    Citation: BMC Cancer 2017 17:786
    Content type: Research article Published on:

  43. Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study i...

    Authors: Yuji Yamashita, Shin Nishiumi, Seishi Kono, Shintaro Takao, Takeshi Azuma and Masaru Yoshida
    Citation: BMC Cancer 2017 17:589
    Content type: Research article Published on:

  45. Data on the long-term risks of non-AIDS defining cancers (NADCs) are limited, especially in Asians. The incidence of NADCs may correlate with the epidemiological trend of cancers or oncogenic infection in each...

    Authors: Naoyoshi Nagata, Takeshi Nishijima, Ryota Niikura, Tetsuji Yokoyama, Yumi Matsushita, Koji Watanabe, Katsuji Teruya, Yoshimi Kikuchi, Junichi Akiyama, Mikio Yanase, Naomi Uemura, Shinichi Oka and Hiroyuki Gatanaga
    Citation: BMC Cancer 2018 18:1066
    Content type: Research article Published on:

  46. Metastatic pancreatic adenocarcinoma (PAC) prognosis remains dismal and gemcitabine monotherapy has been the standard treatment over the last decade. Currently, two first-line regimens are used in this setting...

    Authors: Jean-Baptiste Bachet, Benoist Chibaudel, Franck Bonnetain, Pierre Validire, Pascal Hammel, Thierry André and Christophe Louvet
    Citation: BMC Cancer 2015 15:653
    Content type: Study protocol Published on:

  47. The association between immune-related adverse events (irAEs) and survival outcomes in patients with advanced melanoma receiving therapy with immune checkpoint inhibitors (ICIs) has not been well established, ...

    Authors: Chiao-En Wu, Chan-Keng Yang, Meng-Ting Peng, Pei-Wei Huang, Ching-Fu Chang, Kun-Yun Yeh, Chun-Bing Chen, Chih-Liang Wang, Chao-Wei Hsu, I-Wen Chen, Cheng-Tao Lin, Shir-Hwa Ueng, Gigin Lin, Yu-Fen Lin, Chi-Yuan Cheng and John Wen-Cheng Chang
    Citation: BMC Cancer 2020 20:1018
    Content type: Research article Published on:

  48. Carbonic anhydrases (CAs) have been implicated in the pathogenesis of human cancers. Carbonic anhydrase VII (CA7), a member of the CA gene family, was recently demonstrated to be expressed in several human tis...

    Authors: Guang-Zhen Yang, Liang Hu, Jian Cai, Hai-Yang Chen, Yu Zhang, Dan Feng, Chen-Ye Qi, Yan-Xia Zhai, Hui Gong, Hao Fu, Qing-Ping Cai and Chun-Fang Gao
    Citation: BMC Cancer 2015 15:209
    Content type: Research article Published on:

  50. The gastric cancer incidence rate differs widely across geographical areas. In Italy, in the province of Cremona the incidence is high, compared to the national situation. For this reason a specialized populat...

    Authors: B. M. Donida, G. Tomasello, M. Ghidini, F. Buffoli, M. Grassi, W. Liguigli, G. Maglietta, L. Pergola, M. Ratti, G. Sabadini, L. Toppo, M. Ungari and R. Passalacqua
    Citation: BMC Cancer 2019 19:212
    Content type: Research article Published on:

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