Skip to main content

Articles

3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 49 of 79

  1. Breast cancer is the leading cause of cancer related death in women, with metastasis the principle cause of mortality. New non-invasive prognostic markers are needed for the early detection of metastasis, faci...

    Authors: Peter McAnena, Kahraman Tanriverdi, Catherine Curran, K. Gilligan, Jane E. Freedman, James A. L. Brown and Michael J. Kerin
    Citation: BMC Cancer 2019 19:436
    Content type: Research article Published on:

  2. Combined treatment with cisplatin and gemcitabine (CisGem) is the standard of care for patients with advanced biliary tract cancer (ABC). Selumetinib (AZD6244, ARRY-142886) potently and selectively inhibits ME...

    Authors: John Bridgewater, Andre Lopes, Sandra Beare, Marian Duggan, Dymphna Lee, Maravic Ricamara, Delyth McEntee, Ajithkumar Sukumaran, Harpreet Wasan and Juan W. Valle
    Citation: BMC Cancer 2016 16:153
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Cancer 2016 16:369

  3. Extrahepatic biliary duct cancers (EBDC) are uncommon malignancies characterized by a poor prognosis with high rate of loco-regional recurrence. The purpose of the present study is to assess the feasibility an...

    Authors: Marta Bonet Beltrán, Arnaud D Roth, Gilles Mentha and Abdelkarim S Allal
    Citation: BMC Cancer 2011 11:267
    Content type: Research article Published on:

  4. Modified FOLFIRINOX and gemcitabine plus nab-paclitaxel (GEM-NAB) have been recommended as first-line therapies for advanced pancreatic cancer (PC). Due to the lack of evidence to directly compare them, we con...

    Authors: Jiayuan Chen, Qingling Hua, Haihong Wang, Dejun Zhang, Lei Zhao, Dandan Yu, Guoliang Pi, Tao Zhang and Zhenyu Lin
    Citation: BMC Cancer 2021 21:853
    Content type: Research article Published on:

  5. The E-cadherin gene (CDH1) maps, at chromosome 16q22.1, a region often associated with loss of heterozygosity (LOH) in human breast cancer. LOH at this site is thought to lead to loss of function of this tumor su...

    Authors: José Roberto F Caldeira, Érika C Prando, Francisco C Quevedo, Francisco A Moraes Neto, Cláudia A Rainho and Silvia R Rogatto
    Citation: BMC Cancer 2006 6:48
    Content type: Research article Published on:

  6. The increasing prevalence of cancer detection necessitated practical strategies to deliver highly accurate, beneficial, and dependable processed information together with experimental results. We deleted the c...

    Authors: Marzieh Javadi, Hossein Sazegar and Abbas Doosti
    Citation: BMC Cancer 2023 23:1155
    Content type: Research Published on:

  7. Immunotherapy has transformed cancer treatment patterns for advanced hepatocellular carcinoma (aHCC) in recent years. Therefore, the identification of predictive biomarkers has important clinical implications.

    Authors: Guhe Jia, Lupeng Qiu, Hongye Zheng, Boyu Qin, Zhuoya Sun, Yangyang Shao, Zizhong Yang, Jiakang Shao, Yuxin Zhou and Shunchang Jiao
    Citation: BMC Cancer 2023 23:556
    Content type: Research Published on:

  8. New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes rep...

    Authors: Alyssa A. Hoover, Demetra H. Hufnagel, Whitney Harris, Kennady Bullock, Evan B. Glass, Esther Liu, Whitney Barham, Marta A. Crispens, Dineo Khabele, Todd D. Giorgio, Andrew J. Wilson and Fiona E. Yull
    Citation: BMC Cancer 2020 20:970
    Content type: Research article Published on:

  9. Breast cancer is the most common malignancy that develops in women, responsible for the highest cancer-associated death rates. Triple negative breast cancers represent an important subtype that have an aggress...

    Authors: Kelly A Avery-Kiejda, Stephen G Braye, Andrea Mathe, John F Forbes and Rodney J Scott
    Citation: BMC Cancer 2014 14:51
    Content type: Research article Published on:

  10. Recent studies have reported associations between a variant allele in a let-7 microRNA complementary site (LCS6) within the 3′untranslated region (3′UTR) of KRAS (rs61764370) and clinical outcome in metastatic co...

    Authors: Janne B Kjersem, Tone Ikdahl, Tormod Guren, Eva Skovlund, Halfdan Sorbye, Julian Hamfjord, Per Pfeiffer, Bengt Glimelius, Christian Kersten, Hiroko Solvang, Kjell M Tveit and Elin H Kure
    Citation: BMC Cancer 2012 12:534
    Content type: Research article Published on:

  11. Papillary thyroid carcinoma (PTC) is globally prevalent and associated with an increased risk of lymph node metastasis (LNM). The role of cancer-associated fibroblasts (CAFs) in PTC remains unclear.

    Authors: Yixian Wang, Xin Li, Qingwei Gang, Yinde Huang, Mingyu Liu, Han Zhang, Shikai Shen, Yao Qi and Jian Zhang
    Citation: BMC Cancer 2024 24:710
    Content type: Research Published on:

  12. Leiomyosarcomas represent the largest subtype of soft tissue sarcomas. Two subgroups can be distinguished, non-uterine (NULMS) and uterine leiomyosarcomas (ULMS). The aim of this retrospective study was to eva...

    Authors: Wolfgang Lamm, Camilla Natter, Sophie Schur, Wolfgang J Köstler, Alexander Reinthaller, Michael Krainer, Christoph Grimm, Reinhard Horvath, Gabriele Amann, Philipp Funovics, Thomas Brodowicz and Stephan Polterauer
    Citation: BMC Cancer 2014 14:981
    Content type: Research article Published on:

  13. Trastuzumab resistance is almost inevitable in the management of human epidermal growth factor receptor (HER) 2 positive breast cancer, in which phosphatase and tensin homolog deleted from chromosome 10 (PTEN)...

    Authors: Cheng Du, Xiaomin Yi, Wenchao Liu, Tao Han, Zhaozhe Liu, Zhenyu Ding, Zhendong Zheng, Ying Piao, Jianlin Yuan, Yaling Han, Manjiang Xie and Xiaodong Xie
    Citation: BMC Cancer 2014 14:869
    Content type: Research article Published on:

  14. The patient population with stage III non-small-cell lung cancer (NSCLC) is heterogeneous, with varying staging characteristics and diverse treatment options. Despite the potential practice-changing implicatio...

    Authors: Chieh-Lung Chen, Sing-Ting Wang, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia, Wen-Chien Cheng and Hung-Jen Chen
    Citation: BMC Cancer 2023 23:847
    Content type: Research Published on:

  15. The objectives of this study were to evaluate and model the probability of melanoma-specific death and competing causes of death for patients with melanoma by competing risk analysis, and to build competing ri...

    Authors: Weidong Shen, Naoko Sakamoto and Limin Yang
    Citation: BMC Cancer 2016 16:413
    Content type: Research article Published on:

  16. Aberrant expressions of desmoglein 2 (Dsg2) and desmocollin 2(Dsc2), the two most widely distributed desmosomal cadherins, have been found to play various roles in cancer in a context-dependent manner. Their s...

    Authors: Ji-Yuan Han, Na Che, Jing Mo, Dan-Fang Zhang, Xiao-Hui Liang, Xue-Yi Dong, Xiu-Lan Zhao and Bao-Cun Sun
    Citation: BMC Cancer 2024 24:532
    Content type: Research Published on:

  17. Colorectal cancer (CRC) is one of the most common malignant tumors, influenced by several genetic loci in its clinical phenotypes. The aim of this study was to determine the relationship between the MMP8 gene pol...

    Authors: Shuyong Yu, Jiajia Cheng, Ping Li, Le Tian, Zhuang Chen, Zhaowei Chen, Yongyu Li and Jian Song
    Citation: BMC Cancer 2023 23:1169
    Content type: Research Published on:

  18. Better surgical techniques, chemotherapy and biological therapy have improved survival in patients with colorectal cancer (CRC), most markedly in younger patients. About half of patients over 70 years receive ...

    Authors: C. M. Lund, K. K. Vistisen, C. Dehlendorff, F. Rønholt, J. S. Johansen and D. L. Nielsen
    Citation: BMC Cancer 2017 17:448
    Content type: Study protocol Published on:

  19. Familial colorectal cancer type X (FCCTX) is a phenotypically defined subset of hereditary colorectal cancer with unknown and potentially heterogeneous genetic aetiology. FCCTX has been characterized as a colo...

    Authors: Christina Therkildsen, Maria Rasmussen, Lars Smith-Hansen, Thomas Kallemose, Lars Joachim Lindberg and Mef Nilbert
    Citation: BMC Cancer 2020 20:345
    Content type: Research article Published on:

  21. Radical resection is still the most cost-effectiveness curative strategy for intrahepatic cholangiocarcinoma (ICC), but it remains controversial on the survival benefit of anatomic resection (AR). In this stud...

    Authors: Qiao Ke, Lei Wang, Ziguo Lin, Hongzhi Liu, Jianying Lou, Shuguo Zheng, Xinyu Bi, Jianming Wang, Wei Guo, Fuyu Li, Jian Wang, Yamin Zheng, Jingdong Li, Shi Cheng, Weiping Zhou, Jingfeng Liu…
    Citation: BMC Cancer 2023 23:850
    Content type: Research Published on:

  22. In the era of personalized medicine, head and neck squamous cell carcinoma (HNSCC) represents a critical oncologic topic. Conventional chemotherapy regimens consist of drugs administration in cycles near or at...

    Authors: Francesca De Felice, Daniela Musio and Vincenzo Tombolini
    Citation: BMC Cancer 2015 15:677
    Content type: Review Published on:

  23. Little is known about predictive factors for survival outcomes of esophageal carcinoma (EC) patients who developed recurrence after undergoing multimodal therapies. We aimed to investigate long-term outcomes a...

    Authors: Kotaro Sugawara, Daiji Oka, Hiroki Hara, Takako Yoshii, Hiroki Ushijima, Shigehiro Kudo and Takashi Fukuda
    Citation: BMC Cancer 2023 23:1051
    Content type: Research Published on:

  24. The prognostic value of body composition in cancer patients has been widely studied during the last decade. The main finding of these studies is that sarcopenia, or skeletal muscle depletion, assessed by CT im...

    Authors: Nicolas Charette, Caroline Vandeputte, Lieveke Ameye, Camille Van Bogaert, Jonathan Krygier, Thomas Guiot, Amélie Deleporte, Thierry Delaunoit, Karen Geboes, Jean-Luc Van Laethem, Marc Peeters, Gauthier Demolin, Stéphane Holbrechts, Patrick Flamen, Marianne Paesmans and Alain Hendlisz
    Citation: BMC Cancer 2019 19:134
    Content type: Research article Published on:

  25. Breast cancer is a heterogeneous disease with a highly variable clinical outcome in which both genetic and epigenetic changes have critical roles. We investigated tumor expression levels of histone-modifying e...

    Authors: Remco S Derr, Anneke Q van Hoesel, Anne Benard, Inès J Goossens-Beumer, Anita Sajet, N Geeske Dekker-Ensink, Esther M de Kruijf, Esther Bastiaannet, Vincent THBM Smit, Cornelis JH van de Velde and Peter JK Kuppen
    Citation: BMC Cancer 2014 14:604
    Content type: Research article Published on:

  26. Metastatic melanoma is an incurable disease with an average survival of less than one year. Talabostat is a novel dipeptidyl peptidase inhibitor with immunostimulatory properties.

    Authors: Robert M Eager, C Casey Cunningham, Neil N Senzer, Joe Stephenson Jr, Stephen P Anthony, Steven J O'Day, Gary Frenette, Anna C Pavlick, Barry Jones, Margaret Uprichard and John Nemunaitis
    Citation: BMC Cancer 2009 9:263
    Content type: Research article Published on:

  27. miRNAs, endogenous oligonucleotide RNAs, play an important role in mammary gland carcinogenesis and tumor progression. Detection of their expression and investigation of their functions could lead to discovery...

    Authors: Zheng-sheng Wu, Chao-qun Wang, Ru Xiang, Xue Liu, Shan Ye, Xue-qing Yang, Gui-hong Zhang, Xiao-chun Xu, Tao Zhu and Qiang Wu
    Citation: BMC Cancer 2012 12:51
    Content type: Research article Published on:

  28. Treatment options for advanced thyroid cancer refractory to standard therapies are limited. The safety and efficacy of pembrolizumab were evaluated in patients with advanced differentiated thyroid cancer expre...

    Authors: Janice M. Mehnert, Andrea Varga, Marcia S. Brose, Rahul R. Aggarwal, Chia-Chi Lin, Amy Prawira, Filippo de Braud, Kenji Tamura, Toshihiko Doi, Sarina A. Piha-Paul, Jill Gilbert, Sanatan Saraf, Pradeep Thanigaimani, Jonathan D. Cheng and Bhumsuk Keam
    Citation: BMC Cancer 2019 19:196
    Content type: Research article Published on:

  29. Numerous studies reported genomic alterations in colorectal human tumors but few focused on rectal tumors with the specification of preoperative-treated or untreated tumors. The goals of this study were to lis...

    Authors: Benoît Romain, Agnès Neuville, Nicolas Meyer, Cécile Brigand, Serge Rohr, Anne Schneider, Marie-Pierre Gaub and Dominique Guenot
    Citation: BMC Cancer 2010 10:561
    Content type: Research article Published on:

  30. Cardiac metastasis from colorectal cancer is rare. There is little evidence supporting the effectiveness of chemotherapy, and standard therapy for metastatic cardiac tumors has not been established.

    Authors: Yoshiki Tsujii, Yoshito Hayashi, Akira Maekawa, Tetsuji Fujinaga, Kengo Nagai, Shunsuke Yoshii, Akihiko Sakatani, Satoshi Hiyama, Shinichiro Shinzaki, Hideki Iijima and Tetsuo Takehara
    Citation: BMC Cancer 2017 17:152
    Content type: Case report Published on:

  31. The CD133 transmembrane protein is a well-recognized stem cell marker that has been used to isolate putative cancer stem cell populations from gastric cancers (GCs). However, the molecular features or biomarke...

    Authors: Tae-Min Kim, Yoon Ho Ko, Shin Jung Ha and Han Hong Lee
    Citation: BMC Cancer 2019 19:119
    Content type: Research article Published on:

  32. The complications of radical surgery for cervical cancer can increase patient suffering and affect their quality of life. This retrospective study assessed the safety of radical hysterectomy (RH) with pelvic l...

    Authors: Huang Jing, Wu Xiuhong, Yu Ying, Cheng Xiyun, Luo Deping, Shen Changmei, Wang Qi, Peng Tao and Pan Yiyun
    Citation: BMC Cancer 2022 22:1286
    Content type: Research Published on:

  33. MicroRNA (miR)-214-3p is emerging as an important tumor suppressor in esophageal cancer. In this study, we examined the interaction between miR-214-3p and RAB14, a membrane trafficking protein shown to exert o...

    Authors: Pornima Phatak, Whitney M. Burrows, Timothy Michael Creed, Mariam Youssef, Goo Lee and James M. Donahue
    Citation: BMC Cancer 2022 22:1265
    Content type: Research Published on:

  34. A mouse model of metastasis of human gastric cancer is one of the most important tools for studying the biological mechanisms underlying human gastric cancer metastasis. In this paper, we established a mouse m...

    Authors: Kesheng Li, Huifen Du, Xiaowen Lian, Dandan Chai, Xinwen Li, Rong Yang and Chunya Wang
    Citation: BMC Cancer 2016 16:54
    Content type: Research article Published on:

  36. While programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) checkpoint inhibitors have activity in a proportion of patients with advanced bladder cancer, strongly predictive and prognostic biomarkers...

    Authors: Archana Anantharaman, Terence Friedlander, David Lu, Rachel Krupa, Gayatri Premasekharan, Jeffrey Hough, Matthew Edwards, Rosa Paz, Karla Lindquist, Ryon Graf, Adam Jendrisak, Jessica Louw, Lyndsey Dugan, Sarah Baird, Yipeng Wang, Ryan Dittamore…
    Citation: BMC Cancer 2016 16:744
    Content type: Research article Published on:

  37. The elevated expression of vascular endothelial growth factor C (VEGF-C) is correlated with clinical cervical cancer metastasis and patient survival, which is interpreted by VEGF-C functions to stimulate angio...

    Authors: Mian He, Yang Cheng, Wen Li, Qiongshan Liu, Junxiu Liu, Jinghe Huang and Xiaodong Fu
    Citation: BMC Cancer 2010 10:170
    Content type: Research article Published on:

  39. Amplification of the human epidermal growth factor receptor 2 (HER2) gene occurs in approximately 20% of invasive breast cancer cases and is associated with a more aggressive disease course than HER2-negative bre...

    Authors: Debu Tripathy, Hope S Rugo, Peter A Kaufman, Sandra Swain, Joyce O’Shaughnessy, Mohammad Jahanzeb, Ginny Mason, Mary Beattie, Bongin Yoo, Catherine Lai, Anthony Masaquel and Sara Hurvitz
    Citation: BMC Cancer 2014 14:307
    Content type: Study protocol Published on:

  40. Phosphatase of regenerating liver-3 (PRL-3) has deserved attention as a crucial molecule in the multiple steps of metastasis. In the present study, we examined the mechanisms regulating PRL-3 expression, and a...

    Authors: Akira Ooki, Keishi Yamashita, Shiro Kikuchi, Shinichi Sakuramoto, Natsuya Katada, Mina Waraya, Hiroshi Kawamata, Hiroshi Nishimiya, Kazunori Nakamura and Masahiko Watanabe
    Citation: BMC Cancer 2011 11:122
    Content type: Research article Published on:

  41. Primary hepatic neuroendocrine tumors (PH-NETs) are extremely rare and unknown. Because of its rarity, its prognosis features and influencing factors are not well established.

    Authors: Ziteng Zhang, Xin Zhao, Zhiyan Li, Youchun Wu, Yao Liu, Zhiwei Li and Guobao Li
    Citation: BMC Cancer 2021 21:567
    Content type: Research Published on:

  42. FOLFIRINOX (FFX) and Gemcitabine plus nab-paclitaxel (GnP) have been recommended as the first-line chemotherapy for metastatic pancreatic cancer (mPC). However, the evidence is lacking comparing not only two r...

    Authors: Jung Won Chun, Sang Hyub Lee, Joo Seong Kim, Namyoung Park, Gunn Huh, In Rae Cho, Woo Hyun Paik, Ji Kon Ryu and Yong-Tae Kim
    Citation: BMC Cancer 2021 21:537
    Content type: Research article Published on:

  43. Lymph node (LN) status is the most important prognostic variable used to guide ER positive (+) breast cancer treatment. While a positive nodal status is traditionally associated with a poor prognosis, a subset...

    Authors: Jessica G. Cockburn, Robin M. Hallett, Amy E. Gillgrass, Kay N. Dias, T. Whelan, M. N. Levine, John A. Hassell and Anita Bane
    Citation: BMC Cancer 2016 16:555
    Content type: Research article Published on:

  44. Diffusion-weighted MR imaging (DWI) has increasingly contributed to the management of nasopharyngeal carcinoma (NPC) patients. The objective of this paper was to explore the prognostic significance of apparent...

    Authors: Dan-Fang Yan, Wen-Bao Zhang, Shan-Bao Ke, Feng Zhao, Sen-Xiang Yan, Qi-Dong Wang and Li-Song Teng
    Citation: BMC Cancer 2017 17:678
    Content type: Research article Published on:

  45. Glutamate metabotropic receptors (GRM) play a variety of roles in neuronal cells. However, their clinical significance and biological functions in breast cancer remain unknown.

    Authors: Bin Xiao, Daxiang Chen, Quan Zhou, Jianfeng Hang, Weiyun Zhang, Zhenzhan Kuang, Zhaohui Sun and Linhai Li
    Citation: BMC Cancer 2019 19:891
    Content type: Research article Published on:

  46. The levels of liver function tests (LFTs) are often used to assess liver injury and non-liver disease-related mortality. In our study, the relationship between pretreatment serum LFTs and overall survival (OS)...

    Authors: Hao Huang, Xue-Ping Wang, Xiao-Hui Li, Hao Chen, Xin Zheng, Jian-Hua Lin, Ting Kang, Lin Zhang and Pei-Song Chen
    Citation: BMC Cancer 2017 17:544
    Content type: Research article Published on:

  47. Tumor hypoxia is marked by enhanced expression of hypoxia-inducible factor-α (HIF-1α) and glucose transporter-1 (Glut-1). Hypoxic conditions have also been associated with overexpression of angiogenic factors,...

    Authors: Mariusz Koda, Luiza Kanczuga-Koda, Mariola Sulkowska, Eva Surmacz and Stanislaw Sulkowski
    Citation: BMC Cancer 2010 10:320
    Content type: Research article Published on:

  49. Accurate staging of colorectal cancer (CRC) with clinicopathological parameters is important for predicting prognosis and guiding treatment but provides no information about organ site of metastases. Patterns ...

    Authors: Sjoerd C Bruin, Christiaan Klijn, Gerrit-Jan Liefers, Linde M Braaf, Simon A Joosse, Eric H van Beers, Victor J Verwaal, Hans Morreau, Lodewyk F Wessels, Marie-Louise F van Velthuysen, Rob AEM Tollenaar and Laura J van't Veer
    Citation: BMC Cancer 2010 10:662
    Content type: Research article Published on:

  50. The breast is a rare extranodal site of non-Hodgkin lymphoma, and primary breast lymphoma (PBL) has been arbitrarily defined as disease localized to one or both breasts with or without regional lymph nodes inv...

    Authors: Ho-Young Yhim, Hye Jin Kang, Yoon Hee Choi, Seok Jin Kim, Won Seog Kim, Yee Soo Chae, Jin Seok Kim, Chul Won Choi, Sung Yong Oh, Hyeon Seok Eom, Jeong-A Kim, Jae Hoon Lee, Jong-Ho Won, Hyeok Shim, Je-Jung Lee, Hwa Jung Sung…
    Citation: BMC Cancer 2010 10:321
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Follow

BMC Cancer

ISSN: 1471-2407

Contact us