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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. As a first-line imaging modality, whole-body fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) and 18F-FDG PET/magnetic resonance imaging (MRI) had been widel...

    Authors: Cici Zhang, Zhishan Liang, Wei Liu, Xuwen Zeng and Yuzhen Mo
    Citation: BMC Cancer 2023 23:37
    Content type: Research Published on:

  2. Bladder cancer is the 7th cause of death from cancer in men and 10th in women. Metastatic patients have a poor prognosis with a median overall survival of 14 months. Until recently, vinflunine was the only sec...

    Authors: Marina Pulido, Guilhem Roubaud, Anne-Laure Cazeau, Hakim Mahammedi, Lionel Vedrine, Florence Joly, Loic Mourey, Christian Pfister, Alejandro Goberna, Barbara Lortal, Carine Bellera, Philippe Pourquier and Nadine Houédé
    Citation: BMC Cancer 2018 18:194
    Content type: Research article Published on:

  3. DNA methylation changes occurring in cancer cells are featured with both promoter CpG island hypermethylation and diffuse genomic hypomethylation. Long interspersed element-1 (LINE-1) is repeated in an intersp...

    Authors: Seorin Jeong, Kyoungbun Lee, Xianyu Wen, Younghoon Kim, Nam-Yun Cho, Ja-June Jang and Gyeong Hoon Kang
    Citation: BMC Cancer 2017 17:588
    Content type: Research article Published on:

  4. It is urgent to find some biochemical markers for predicting the radiochemotherapy sensitivity. microRNAs have a huge potential as a predictive biomarker in gastric cancer. The current study aims to identify t...

    Authors: Xiaowen Liu, Hong Cai, Weiqi Sheng, Hua Huang, Ziwen Long and Yanong Wang
    Citation: BMC Cancer 2018 18:1048
    Content type: Research article Published on:

  5. SNP309 T/G (rs2279744) causes higher levels of MDM2, the most important negative regulator of the p53 tumor suppressor. SNP72 G/C (rs1042522) gives rise to a p53 protein with a greatly reduced capacity to indu...

    Authors: Joerg Bittenbring, Frédérique Parisot, Alain Wabo, Monika Mueller, Lynn Kerschenmeyer, Markus Kreuz, Lorenz Truemper, Olfert Landt, Alain Menzel, Michael Pfreundschuh and Klaus Roemer
    Citation: BMC Cancer 2008 8:116
    Content type: Research article Published on:

  6. Brain metastases from sarcomatous lesions pose a management challenge owing to their rarity and the histopathological heterogeneity. Prognostic indices such as the Graded Prognostic Assessment (GPA) index have...

    Authors: Anna Patrikidou, Loic Chaigneau, Nicolas Isambert, Kyriaki Kitikidou, Ryan Shanley, Isabelle Ray-Coquard, Thibaud Valentin, Bettina Malivoir, Maryline Laigre, Jacques-Olivier Bay, Laurence Moureau-Zabotto, Emmanuelle Bompas, Sophie Piperno-Neumann, Nicolas Penel, Thierry Alcindor, Cécile Guillemet…
    Citation: BMC Cancer 2020 20:117
    Content type: Research article Published on:

  7. Early diagnosis is important for the timely treatment of gallbladder carcinoma (GBC) patients and may lead to increased survival outcomes. Here, we have applied serological proteome analysis (SERPA), an immuno...

    Authors: Javed Akhtar, Ratna Priya, Vaishali Jain, Puja Sakhuja, Anil Kumar Agarwal, Surbhi Goyal, Ravindra Varma Polisetty, Ravi Sirdeshmukh, Sudeshna Kar and Poonam Gautam
    Citation: BMC Cancer 2020 20:1175
    Content type: Research article Published on:

  8. Rhabdomyosarcoma is the most common soft tissue sarcoma in children, but rare in adults. Para-meningeal rhabdomyosarcoma in head and neck (PM-HNRMS) is less applicable for surgery due to the anatomic reason. P...

    Authors: Kenji Tsuchihashi, Mamoru Ito, Shuji Arita, Hitoshi Kusaba, Wataru Kusano, Takashi Matsumura, Takafumi Kitazono, Shohei Ueno, Ryosuke Taguchi, Tomoyasu Yoshihiro, Yasuhiro Doi, Kohei Arimizu, Hirofumi Ohmura, Tatsuhiro Kajitani, Kenta Nio, Michitaka Nakano…
    Citation: BMC Cancer 2023 23:1046
    Content type: Research Published on:

  9. Macrophage inhibitory cytokine 1 (MIC-1/GDF15) has been identified as a potential novel biomarker for detection of pancreatic cancer (PCa). However, the diagnostic value of serum MIC-1 for pancreatic ductal ad...

    Authors: Xiaobing Wang, Yanfen Li, Haimei Tian, Jun Qi, Mo Li, Chao Fu, Fan Wu, Yi Wang, Dongwan Cheng, Wenya Zhao, Chao Zhang, Teng Wang, Jianyu Rao and Wei Zhang
    Citation: BMC Cancer 2014 14:578
    Content type: Research article Published on:

  10. Identification of new cancer antigens is necessary for the efficient diagnosis and immunotherapy. A variety of tumor antigens have been identified by several methodologies. Among those antigens, cancer/testis ...

    Authors: Tadashi Hanafusa, Ali Eldib Ali Mohamed, Shohei Domae, Eiichi Nakayama and Toshiro Ono
    Citation: BMC Cancer 2012 12:520
    Content type: Research article Published on:

  11. Following curative-intent neoadjuvant therapy in locally advanced rectal cancer, metastatic progression is still dominant. We investigated if patients’ circulating 25-hydroxyvitamin D [25(OH)D] levels were ass...

    Authors: Hanna Abrahamsson, Alina C. Porojnicu, Jonas C. Lindstrøm, Svein Dueland, Kjersti Flatmark, Knut H. Hole, Therese Seierstad, Johan Moan, Kathrine Røe Redalen, Sebastian Meltzer and Anne Hansen Ree
    Citation: BMC Cancer 2019 19:488
    Content type: Research article Published on:

  12. Osteosarcoma (OS) is one of the malignant bone tumors with strong aggressiveness and poor prognosis. Leucine-rich repeats and immunoglobulin-like domains2 (LRIG2) is closely associated with the poor prognosis ...

    Authors: Zhi-Qiang Li, Wei-Jie Liao, Bo-Lin Sun, Zhi-Wen Luo, Nan-Shan Zhong, Jia-Bao Wu, Zhi-Li Liu and Jia-Ming Liu
    Citation: BMC Cancer 2022 22:1029
    Content type: Research Published on:

  13. Colorectal cancer (CRC) is the third most widespread cancer and the fourth leading lethal disease among different societies. It is thought that CRC accounts for about 10% of all newly diagnosed cancer cases wi...

    Authors: Marziyeh Sadat Moslehian, Roya Shabkhizan, Mohammad Reza Asadi, Ahad Bazmani, Mahdi Mahdipour, Sanya Haiaty, Reza Rahbarghazi and Ebrahim Sakhinia
    Citation: BMC Cancer 2023 23:512
    Content type: Research Published on:

  14. In ovarian cancer, the reported rate of EGFR expression varies between 4-70% depending on assessment method and data on patient outcome are conflicting. Methods: In this study we investigated EGFR expression a...

    Authors: Aurelia Noske, Michael Schwabe, Wilko Weichert, Silvia Darb-Esfahani, Ann-Christin Buckendahl, Jalid Sehouli, Elena I Braicu, Jan Budczies, Manfred Dietel and Carsten Denkert
    Citation: BMC Cancer 2011 11:294
    Content type: Research article Published on:

  15. Pancreatic cancer is the foremost contributor to cancer-related deaths globally, and its prevalence continues to rise annually. Nevertheless, the underlying mechanisms behind its development remain unclear and...

    Authors: Feng Zhao, Anli Chen, Xiaotian Wu, Xiangyu Deng, Jiali Yang and Jianjiang Xue
    Citation: BMC Cancer 2024 24:478
    Content type: Research Published on:

  16. The 8th edition of the tumor-node-metastasis (TNM) classification classifies inguinal lymph nodes as regional lymph nodes for anal canal carcinoma but non-regional lymph nodes for rectal carcinoma. This differ...

    Authors: Taro Tanabe, Dai Shida, Sho Komukai, Yuya Nakamura, Shunsuke Tsukamoto and Yukihide Kanemitsu
    Citation: BMC Cancer 2019 19:733
    Content type: Research article Published on:

  18. The sialic acid binding Ig like lectin 15 (Siglec-15) was previously identified as tumor immune suppressor gene in some human cancers with elusive molecular mechanism to be elucidated. The continuous focus on ...

    Authors: Xingzhi Li, Ziji Liang, Jiexin Pan, Meng Zhang, Jinli Liu, Rong Hu and Caiyan Liao
    Citation: BMC Cancer 2024 24:328
    Content type: Research Published on:

  19. We have recently described the correlation between quantitative measures of HER2 expression or HER2 homodimers by the HERmark assay and objective response (RR), time-to progression (TTP), and overall survival ...

    Authors: Masakazu Toi, Jeff Sperinde, Weidong Huang, Shigehira Saji, John Winslow, Xueguang Jin, Yuping Tan, Shinji Ohno, Seigo Nakamura, Hiroji Iwata, Norikazu Masuda, Kenjiro Aogi, Satoshi Morita, Christos Petropoulos and Michael Bates
    Citation: BMC Cancer 2010 10:56
    Content type: Research article Published on:

  20. Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer. Golgi re...

    Authors: Qiong Song, Qiu Chen, Qimin Wang, Longqiu Yang, Dongdong Lv, Guangli Jin, Jiaying Liu, Baolin Li and Xuejie Fei
    Citation: BMC Cancer 2018 18:255
    Content type: Research article Published on:

  22. Disruption of cellular processes in the breast by abnormally expressed miRNA is characterized to develop cancer. We aimed to identify the differential expression of small RNAs (sRNAs) and mRNAs in formalin-fix...

    Authors: Sevan Omer Majed and Suhad Asad Mustafa
    Citation: BMC Cancer 2021 21:473
    Content type: Research Published on:

  23. A self-help workbook is expected to support cancer patients to cope with physical and psychosocial distress, to facilitate communication with medical staff, and to improve quality of life (QOL). We conducted a...

    Authors: Toshimi Takano, Ayako Matsuda, Noriko Ishizuka, Yukinori Ozaki, Koichi Suyama, Yuko Tanabe, Yuji Miura and Eisuke Matsushima
    Citation: BMC Cancer 2021 21:588
    Content type: Research article Published on:

  24. Pancreatic adenocarcinoma (PAAD) is characterized by low antitumour immune cell infiltration in an immunosuppressive microenvironment. This study aimed to systematically explore the impact on prognostic altern...

    Authors: Bo Chen, Tuo Deng, Liming Deng, Haitao Yu, Bangjie He, Kaiyu Chen, Chongming Zheng, Daojie Wang, Yi Wang and Gang Chen
    Citation: BMC Cancer 2021 21:1211
    Content type: Research Published on:

  25. To determine whether additional chemotherapy after concurrent chemoradiation (CCRT) improves survival outcomes in patients with early cervical cancer who undergo radical hysterectomy (RH).

    Authors: Se Ik Kim, Jeong Yun Kim, Chan Woo Wee, Maria Lee, Hee Seung Kim, Hyun Hoon Chung, Taek Sang Lee, Hye Won Jeon, Noh Hyun Park, Yong Sang Song and Tae Hun Kim
    Citation: BMC Cancer 2021 21:1260
    Content type: Research Published on:

  26. Studies of several tumour types have shown that expression profiling of cellular protein extracted from surgical tissue specimens by direct mass spectrometry analysis can accurately discriminate tumour from no...

    Authors: Christopher CL Liao, Nicholas Ward, Simon Marsh, Tan Arulampalam and John D Norton
    Citation: BMC Cancer 2010 10:410
    Content type: Research article Published on:

  27. Regulatory T cells (Tregs) play an important role in the antitumor immune response in epithelial ovarian cancer (EOC). To understand the immune-inhibitory networks of EOC, we addressed the association between ...

    Authors: Sho Sato, Hirokazu Matsushita, Daisuke Shintani, Yukari Kobayashi, Nao Fujieda, Akira Yabuno, Tadaaki Nishikawa, Keiichi Fujiwara, Kazuhiro Kakimi and Kosei Hasegawa
    Citation: BMC Cancer 2022 22:437
    Content type: Research Published on:

  28. B7 molecules play significant roles in regulating tumor immunity, but their expression patterns and immuno-biological correlations in pancreatic cancer (PaCa) have not been fully discussed.

    Authors: Jiayue Yang, Zhen Tian, Han Gao, Fan Xiong, Cuiping Cao, Jiaojiao Yu, Wei Shi, Qiang Zhan and Cheng Yang
    Citation: BMC Cancer 2022 22:584
    Content type: Research Published on:

  30. There is still much debate about the best adjuvant therapy after surgery for endometrial cancer (EC) and there are no current guidelines. Radiotherapy (RT) alone does not seem to improve overall survival. We i...

    Authors: Giorgia Mangili, Patrizia De Marzi, Saverio Beatrice, Emanuela Rabaiotti, Riccardo Viganò, Luigi Frigerio, Cinzia Gentile and Ferruccio Fazio
    Citation: BMC Cancer 2006 6:198
    Content type: Research article Published on:

  31. In recent years, emerging studies have demonstrated critical functions and potential clinical applications of long non-coding RNA (lncRNA) in osteosarcoma. To further validate the prognostic value of multiple ...

    Authors: Wenchao Zhang, Xiaolei Ren, Lin Qi, Chenghao Zhang, Chao Tu and Zhihong Li
    Citation: BMC Cancer 2021 21:202
    Content type: Research article Published on:

  32. Triple negative breast cancers (TNBC) possess cell dedifferentiation characteristics, carry out activities connate to those of cancer stem cells (CSCs) and are associated with increased metastasis, as well as,...

    Authors: Oluwaseun Adebayo Bamodu, Wen-Chien Huang, Wei-Hwa Lee, Alexander Wu, Liang Shun Wang, Michael Hsiao, Chi-Tai Yeh and Tsu-Yi Chao
    Citation: BMC Cancer 2016 16:160
    Content type: Research article Published on:

  33. Circulating tumor cells (CTCs) have shown prognostic relevance in many cancer types. However, the majority of current CTC capture methods rely on positive selection techniques that require a priori knowledge a...

    Authors: Weiqiang Chen, Steven G. Allen, Ajaya Kumar Reka, Weiyi Qian, Shuo Han, Jianing Zhao, Liwei Bao, Venkateshwar G. Keshamouni, Sofia D. Merajver and Jianping Fu
    Citation: BMC Cancer 2016 16:614
    Content type: Research article Published on:

  34. The purpose of this study has been to establish the level of RCAS1 – a membrane protein expressed in various cancer cells and able to induce apoptosis of CTLs and NK cells in pharyngeal and laryngeal cancer an...

    Authors: Magdalena Dutsch-Wicherek, Romana Tomaszewska, Agata Lazar, Lukasz Wicherek and Jacek Skladzien
    Citation: BMC Cancer 2009 9:35
    Content type: Research article Published on:

  35. Cholangiocarcinoma (CHOL) is the second most common primary hepatic malignant tumor, following hepatocellular carcinoma (HCC). CHOL is highly aggressive and heterogeneous resulting in poor prognosis. The diagn...

    Authors: Shuochen Liu, Shilong Fan, Yirui Wang, Ruixiang Chen, Ziyi Wang, Yaodong Zhang, Wangjie Jiang, Yananlan Chen, Xiao Xu, Yue Yu, Changxian Li and Xiangcheng Li
    Citation: BMC Cancer 2023 23:444
    Content type: Research Published on:

  36. CDK4 is a protein kinase in the CDK family important for G1/S phase cell cycle progression. However, the roles and molecular mechanisms of CDK4 triggering nasopharynx carcinogenesis are still unclear.

    Authors: Zhen Liu, Xiaobin Long, Cheng Chao, Chen Yan, Qiangyun Wu, Shengni Hua, Yajie Zhang, Aibing Wu and Weiyi Fang
    Citation: BMC Cancer 2014 14:274
    Content type: Research article Published on:

  37. Since the “War on Cancer” was declared in 1971, the United States alone has expended some $300 billion on research, with a heavy focus on the role of genomics in anticancer therapy. Voluminous data have been c...

    Authors: Björn LDM Brücher, Gary Lyman, Richard van Hillegersberg, Raphael E Pollock, Florian Lordick, Han-Kwang Yang, Toshikazu Ushijima, Khay-Guan Yeoh, Tomas Skricka, Wojciech Polkowski, Grzegorz Wallner, Vic Verwaal, Alfredo Garofalo, Domenico D’Ugo, Franco Roviello, Hans-Ulrich Steinau…
    Citation: BMC Cancer 2014 14:186
    Content type: Debate Published on:

  38. T-cell immunoglobulin mucin-1 (TIM-1) has been reported to be associated with the biological behavior of several malignant tumors; however, it is not clear whether it has a role in cervical cancer (CC).

    Authors: Liuyan Chen, Jilin Qing, Yangyang Xiao, Xiaomei Huang, Yanlin Chi and Zhizhong Chen
    Citation: BMC Cancer 2022 22:370
    Content type: Research article Published on:

  39. Kaempferol, a natural flavonoid, exhibits anticancer properties by scavenging reactive oxygen species (ROS). However, increasing evidence has demonstrated that, under certain conditions, kaempferol can inhibit...

    Authors: Fengjiao Wang, Lai Wang, Chao Qu, Lianyu Chen, Yawen Geng, Chienshan Cheng, Shulin Yu, Dan Wang, Lina Yang, Zhiqiang Meng and Zhen Chen
    Citation: BMC Cancer 2021 21:396
    Content type: Research Published on:

  41. c-Met, one of current potential hot targets, has been suggested as a potential tumor marker in the development of esophageal squamous cell carcinoma (ESCC). Our aim was to investigate the expression of c-Met i...

    Authors: Yingying Xu, Zhi Peng, Zhongwu Li, Ming Lu, Jing Gao, Yilin Li, Yanyan Li and Lin Shen
    Citation: BMC Cancer 2015 15:6
    Content type: Research article Published on:

  42. Investigating novel therapeutic strategies for colorectal cancer (CRC) is imperative. However, there is limited research on the use of drugs to target peripheral blood immune cells in this context. To address ...

    Authors: Runze Huang, Xin Jin, Ziting Jiang, Yixiu Wang, Yibin Wu, Lu Wang and Weiping Zhu
    Citation: BMC Cancer 2024 24:753
    Content type: Research Published on:

  43. Serum C-reactive protein (CRP), an acute inflammatory response biomarker, has been recognized as an indicator of malignant disease progression. However, the prognostic significance of CRP levels collected befo...

    Authors: Zi-Ying Lin, Zhen-Xing Liang, Pei-Lin Zhuang, Jie-Wei Chen, Yun Cao, Li-Xu Yan, Jing-Ping Yun, Dan Xie and Mu-Yan Cai
    Citation: BMC Cancer 2016 16:792
    Content type: Research article Published on:

  44. MYC overexpression is associated with poor prognosis in breast tumors (BCa). The objective of this study was to determine the prevalence of MYC amplification and associated markers in BCa tumors from African A...

    Authors: Tammey J. Naab, Anita Gautam, Luisel Ricks-Santi, Ashwini K. Esnakula, Yasmine M. Kanaan, Robert L. DeWitty, Girmay Asgedom, Khepher H. Makambi, Massih Abawi and Jan K. Blancato
    Citation: BMC Cancer 2018 18:274
    Content type: Research article Published on:

  45. There is a growing level of interest in the potential role inflammation has on the initiation and progression of malignancy. Notable examples include Helicobacter pylori-mediated inflammation in gastric cancer an...

    Authors: Emily McIlvanna, Gerard J. Linden, Stephanie G. Craig, Fionnuala T. Lundy and Jacqueline A. James
    Citation: BMC Cancer 2021 21:1212
    Content type: Review Published on:

  46. Animal model experiments have suggested a role of the DNA repair protein ERCC1 (Excision Repair Cross-Complementation Group 1) in prostate cancer progression.

    Authors: Frank Jacobsen, Billurvan Taskin, Nathaniel Melling, Charlotte Sauer, Corinna Wittmer, Claudia Hube-Magg, Martina Kluth, Ronald Simon, Dirk Pehrke, Burkhard Beyer, Thomas Steuber, Imke Thederan, Guido Sauter, Thorsten Schlomm, Waldemar Wilczak, Katharina Möller…
    Citation: BMC Cancer 2017 17:504
    Content type: Research article Published on:

  47. Patient satisfaction is an important indicator of the quality of healthcare. Pain is one of the most common symptoms among cancer patients that needs optimal treatment; rather, it compromises the quality of li...

    Authors: Molla Amsalu, Henos Enyew Ashagrie, Amare Belete Getahun and Yophtahe Woldegerima Berhe
    Citation: BMC Cancer 2024 24:647
    Content type: Research Published on:

  48. The proto-oncogene pituitary tumor-transforming gene (PTTG) has been shown to be abundantly overexpressed in a large variety of neoplasms likely promoting neo-vascularization and tumor invasiveness. In this st...

    Authors: Christine Solbach, Marc Roller, Frank Eckerdt, Silke Peters and Rainald Knecht
    Citation: BMC Cancer 2006 6:242
    Content type: Research article Published on:

  49. Cancer associated fibroblasts (CAFs) can remodel tumor microenvironment by secreting exosomes. This study aimed to investigate the role of exosomes derived from cancer-associated fibroblasts in colorectal canc...

    Authors: Cheng Yang, Yan Zhang, Mingze Yan, Jiahao Wang, Jiaming Wang, Muhong Wang, Yuhong Xuan, Haiyue Cheng, Jiaao Ma, Cuicui Chai, Mingzhe Li and Zhiwei Yu
    Citation: BMC Cancer 2024 24:64
    Content type: Research Published on:

  50. The relationship between cancer and coagulation has been intensively studied in recent years; however, the effects of coagulation factors on oral squamous cell carcinoma (OSCC) have rarely been reported. This ...

    Authors: Yu-jie Liang, Xue-ying Mei, Bin Zeng, Si-en Zhang, Le Yang, Xiao-mei Lao and Gui-qing Liao
    Citation: BMC Cancer 2021 21:122
    Content type: Research article Published on:

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