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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 36 of 79

  1. Pancreatic cancer remains one of the most difficult cancers to treat with the poorest prognosis. The key to improving survival rates in this disease is early detection and monitoring of disseminated and residu...

    Authors: Julie Earl, Sandra Garcia-Nieto, Jose Carlos Martinez-Avila, José Montans, Alfonso Sanjuanbenito, Mercedes Rodríguez-Garrote, Eduardo Lisa, Elena Mendía, Eduardo Lobo, Núria Malats, Alfredo Carrato and Carmen Guillen-Ponce
    Citation: BMC Cancer 2015 15:797
    Content type: Research article Published on:

  2. The clinical significance of tertiary lymphoid structures (TLSs) is not well-documented in early oral tongue squamous cell carcinoma (OTSCC).

    Authors: Alhadi Almangush, Ibrahim O. Bello, Amr Elseragy, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Pentti Nieminen, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo and Ilmo Leivo
    Citation: BMC Cancer 2022 22:1108
    Content type: Research Published on:

  3. The majority of people with cancer have at least one other chronic health condition. With each additional chronic disease, the complexity of their care increases, as does the potential for negative outcomes in...

    Authors: Anna Péfoyo Koné and Deborah Scharf
    Citation: BMC Cancer 2021 21:406
    Content type: Research article Published on:

  4. The present commonly used five-year survival rates are not adequate to represent the statistical cure. In the present study, we established the minimum number of years required for follow-up to estimate statis...

    Authors: Patricia Tai, Edward Yu, Gábor Cserni, Georges Vlastos, Melanie Royce, Ian Kunkler and Vincent Vinh-Hung
    Citation: BMC Cancer 2005 5:48
    Content type: Research article Published on:

  5. Androgen deprivation therapy is the primary strategy for the treatment of advanced prostate cancer; however, after an initial regression, most patients will inevitably develop a fatal androgen-independent tumo...

    Authors: Xiaolu Wang, Haitao Gao, Lixin Ren, Junfei Gu, Yanping Zhang and Yong Zhang
    Citation: BMC Cancer 2014 14:308
    Content type: Research article Published on:

  6. Bone metastases commonly occur in conjunction with solid tumors, and are associated with serious bone complications. Population-based estimates of bone metastasis incidence are limited, often based on autopsy ...

    Authors: Rohini K. Hernandez, Sally W. Wade, Adam Reich, Melissa Pirolli, Alexander Liede and Gary H. Lyman
    Citation: BMC Cancer 2018 18:44
    Content type: Research article Published on:

  8. Neuroendocrine carcinoma of the cervix (NECC) is a rare variant of cervical cancer. The prognosis of women with NECC is poor and there is no standardized therapy for this type of malignancy based on controlled...

    Authors: Clemens B. Tempfer, Iris Tischoff, Askin Dogan, Ziad Hilal, Beate Schultheis, Peter Kern and Günther A. Rezniczek
    Citation: BMC Cancer 2018 18:530
    Content type: Research article Published on:

  9. In recent years, there has been growing evidence indicating a relationship between liquid–liquid phase separation (LLPS) and cancer development. However, to date, the clinical significance of LLPS in skin cuta...

    Authors: Jianlan Liu, Shengbin Pei, Pengpeng Zhang, Keyu Jiang, Binlin Luo, Zuoqiong Hou, Gang Yao and Jian Tang
    Citation: BMC Cancer 2023 23:388
    Content type: Research Published on:

  10. Secreted Wnt signaling antagonists have recently been described as frequent targets of epigenetic inactivation in human tumor entities. Since gene silencing of certain Wnt antagonists was found to be correlate...

    Authors: Jürgen Veeck, Peter J Wild, Thomas Fuchs, Peter J Schüffler, Arndt Hartmann, Ruth Knüchel and Edgar Dahl
    Citation: BMC Cancer 2009 9:217
    Content type: Research article Published on:

  11. Costimulatory signaling has been implicated as a potential regulator of antitumor immunity in various human cancers. In contrast to the negative prognostic value of aberrant B7-H1 expression by pancreatic canc...

    Authors: Martin Loos, Dennis M Hedderich, Malte Ottenhausen, Nathalia A Giese, Melanie Laschinger, Irene Esposito, Jörg Kleeff and Helmut Friess
    Citation: BMC Cancer 2009 9:463
    Content type: Research article Published on:

  12. The prognoses of head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC) are poor, especially when both tumors occur at the same time. We examined the clonal relatedness of ...

    Authors: Somkiat Sunpaweravong, Sacarin Bunbanjerdsuk, Tanjitti Pongrujikorn, Chaiwat Naktang, Patrapim Sunpaweravong, Anupong Nitiruangjaras, Tanadech Dechaphankul and Natini Jinawath
    Citation: BMC Cancer 2019 19:1174
    Content type: Research article Published on:

  14. Osteosarcoma (OS) is the most common primary bone tumor, with a propensity to metastasize to the lungs. Five-year survival for metastatic OS is below 30%, and has not improved for several decades despite the i...

    Authors: Shibing Yu, Mitchell Stephen Fourman, Adel Mahjoub, Jonathan Brendan Mandell, Jared Anthony Crasto, Nicholas Giuseppe Greco and Kurt Richard Weiss
    Citation: BMC Cancer 2017 17:78
    Content type: Research article Published on:

  15. Heparan sulfate proteoglycans (HSPGs) are complex molecules involved in the growth, invasion and metastatic properties of cancerous cells. This study analyses the alterations in the expression patterns of thes...

    Authors: Iván Fernández-Vega, Olivia García-Suárez, Beatriz García, Ainara Crespo, Aurora Astudillo and Luis M. Quirós
    Citation: BMC Cancer 2015 15:742
    Content type: Research article Published on:

  16. TUBA1C is an α-tubulin isoform involved in mitosis, and its dysregulation has been implicated in tumor progression. There is still no clear understanding of its role in bladder urothelial carcinoma (BLCA).

    Authors: Yi Jiang, Chao Zhu, Haoxuan Huang, Gaomin Huang, Bin Fu and Xiaoqing Xi
    Citation: BMC Cancer 2023 23:716
    Content type: Research Published on:

  17. Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread occurrence in cancer genome could inactivate many cellular pathways including DNA repair, cell cycle control, apoptosis, c...

    Authors: Hui-Juan Yang, Vincent WS Liu, Yue Wang, Percy CK Tsang and Hextan YS Ngan
    Citation: BMC Cancer 2006 6:212
    Content type: Research article Published on:

  19. Prognostic markers specific to a particular cancer type can assist in the evaluation of survival probability of patients and help clinicians to assess the available treatment modalities.

    Authors: Deepankar Chakroborty, Maheswara Reddy Emani, Riku Klén, Camilla Böckelman, Jaana Hagström, Caj Haglund, Ari Ristimäki, Riitta Lahesmaa and Laura L. Elo
    Citation: BMC Cancer 2019 19:727
    Content type: Research article Published on:

  20. The clinical significance between particularly interesting new cysteine-histidine rich protein (PINCH) expression and radiotherapy (RT) in tumours is not known. In this study, the expression of PINCH and its r...

    Authors: Annica Holmqvist, Jingfang Gao, Birgitta Holmlund, Gunnar Adell, John Carstensen, Dianne Langford and Xiao-Feng Sun
    Citation: BMC Cancer 2012 12:65
    Content type: Research article Published on:

  21. The circadian clock and cell cycle are two global regulatory systems that have pervasive behavioral and physiological effects on eukaryotic cells, and both play a role in cancer development. Recent studies hav...

    Authors: Yingying Mao, Alan Fu, Derek Leaderer, Tongzhang Zheng, Kun Chen and Yong Zhu
    Citation: BMC Cancer 2013 13:498
    Content type: Research article Published on:

  22. Much attention has been recently focused on the role of cancer stem cells (CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to proliferate and self-renew extensively, thus sus...

    Authors: Gabriella Ferrandina, Enrica Martinelli, Marco Petrillo, Maria Grazia Prisco, Gianfranco Zannoni, Stefano Sioletic and Giovanni Scambia
    Citation: BMC Cancer 2009 9:221
    Content type: Research article Published on:

  23. PD-L1 was an important biomarker in lung adenocarcinoma. The study was to confirm the most important factor affecting the expression of PD-L1 remains undetermined.

    Authors: Fang Lu, Ernuo Wang and Haiquan Liu
    Citation: BMC Cancer 2024 24:642
    Content type: Research Published on:

  25. Platelet to Lymphocyte ratio (PLR) is thought to be associated with a worse outcome in multiple types of cancer. However, the prognostic significance of PLR has not been investigated in the prostate cancer (PC...

    Authors: Yanqing Wang, Fan Xu, Jiahua Pan, Yinjie Zhu, Xiaoguang Shao, Jianjun Sha, Zezhou Wang, Yong Cai, Qiang Liu, Baijun Dong, Wei Xue and Yiran Huang
    Citation: BMC Cancer 2016 16:329
    Content type: Research article Published on:

  26. In metastatic breast cancer, the status of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), as well as the Ki-67 index sometimes change between prima...

    Authors: Hitoshi Inari, Nobuyasu Suganuma, Kae Kawachi, Tatsuya Yoshida, Takashi Yamanaka, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Hirotaka Nakayama, Ayumi Yamanaka, Katsuhiko Masudo, Takashi Oshima, Tomoyuki Yokose, Yasushi Rino, Satoru Shimizu, Yohei Miyagi and Munetaka Masuda
    Citation: BMC Cancer 2017 17:160
    Content type: Research article Published on:

  27. We aimed to validate prognostic scores for survival in patients undergoing chemotherapy for advanced or metastatic cancer after first-line treatment.

    Authors: Olivier Trédan, Isabelle Ray-Coquard, Gisèle Chvetzoff, Paul Rebattu, Agathe Bajard, Sylvie Chabaud, David Pérol, Chadi Saba, Florent Quiblier, Jean-Yves Blay and Thomas Bachelot
    Citation: BMC Cancer 2011 11:95
    Content type: Research article Published on:

  28. Diagnosis and treatment of diffuse malignant peritoneal mesothelioma (DMPM) are still challenging. The aim of the present study was to explore the correlation between CD74, CD10, Ki-67 and clinicopathological ...

    Authors: Yufei Liang, Chunying Li, Yingying Liu, Liang Tian and Dongliang Yang
    Citation: BMC Cancer 2023 23:406
    Content type: Research Published on:

  29. The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult. Patients eventually presenting with clinically appar...

    Authors: Charlotte E L Klaver, Gijsbert D Musters, Willem A Bemelman, Cornelis J A Punt, Victor J Verwaal, Marcel GW Dijkgraaf, Arend GJ Aalbers, Jarmila DW van der Bilt, Djamila Boerma, Andre JA Bremers, Jacobus WA Burger, Christianne J Buskens, Pauline Evers, Robert J van Ginkel, Wilhelmina MU van Grevenstein, Patrick HJ Hemmer…
    Citation: BMC Cancer 2015 15:428
    Content type: Study protocol Published on:

  30. Ovarian cancer (OC) is a life-threatening gynecological malignancy where dysregulation of microRNAs (miRNAs) is frequently implicated. This study focuses on the function of miR-545 on OC development and the mo...

    Authors: Hailing Zhang, Ke Zhang, Zhen Xu, Zhilong Chen, Qian Wang, Chenyang Wang and Jinquan Cui
    Citation: BMC Cancer 2021 21:163
    Content type: Research article Published on:

  31. Growth differentiation factor 15 (GDF15) has attracted much interest as a novel biomarker for epithelial ovarian carcinoma (EOC). Research focus has been directed at GDF15 as a diagnostic detection, while the ...

    Authors: Dan Zhao, Xiaobing Wang and Wei Zhang
    Citation: BMC Cancer 2018 18:328
    Content type: Research article Published on:

  32. Parathyroid hormone-related peptide (PTHrP) overexpression and poor patient outcome have been reported for many human tumors, but no studies are available in laryngeal cancer. Therefore, we studied the express...

    Authors: Giovanni Almadori, Antonella Coli, Eugenio De Corso, Dario Antonio Mele, Stefano Settimi, Giovanni Di Cintio, Francesca Brigato, Domenico Scannone, Libero Lauriola and Franco Oreste Ranelletti
    Citation: BMC Cancer 2022 22:704
    Content type: Research Published on:

  33. Budding is a complementary prognostic factor for colorectal cancer. In this study, we aimed to clarify the role of tumor budding in rectal cancer patients after preoperative chemoradiotherapy.

    Authors: Iryna Trotsyuk, Halina Sparschuh, Alice Josephine Müller, Konrad Neumann, Martin Kruschewski, David Horst and Sefer Elezkurtaj
    Citation: BMC Cancer 2019 19:1033
    Content type: Research article Published on:

  34. Breast cancer (BC) is the most common malignant tumor among women worldwide. Tissue transglutaminase 2 (TG2) has been reported as a major player across several types of cancer. However, the effects of TG2 in brea...

    Authors: Dahai Xu, Ning Xu, Liang Sun, Zhaoying Yang, Miao He and Youjun Li
    Citation: BMC Cancer 2022 22:1267
    Content type: Research Published on:

  35. Research shows disparities in cancer outcomes by ethnicity or socio-economic status. Therefore, it is the aim of our study to perform a matched-pair analysis which compares the outcome of German and non-German...

    Authors: Marie K. Budde, Walther Kuhn, Mignon-Denise Keyver-Paik, Friedrich Bootz, Jörg C. Kalff, Stefan C. Müller, Thomas Bieber, Peter Brossart, Hartmut Vatter, Ulrich Herrlinger, Dieter C. Wirtz, Hans H. Schild, Glen Kristiansen, Thorsten Pietsch, Stefan Aretz, Franziska Geiser…
    Citation: BMC Cancer 2019 19:1024
    Content type: Research article Published on:

  36. Cancer is a major public health issue and represents a significant economic burden to health care systems worldwide. The objective of this analysis was to estimate phase-specific, 5-year and lifetime net costs...

    Authors: Claire de Oliveira, Reka Pataky, Karen E. Bremner, Jagadish Rangrej, Kelvin K. W. Chan, Winson Y. Cheung, Jeffrey S. Hoch, Stuart Peacock and Murray D. Krahn
    Citation: BMC Cancer 2016 16:809
    Content type: Research article Published on:

  37. Recent studies have shown that breast cancer subtype can change from the primary tumour to the recurrence. Discordance between primary and recurrent breast cancer has implications for further treatment and ult...

    Authors: Peter F. McAnena, Andrew McGuire, A. Ramli, C. Curran, C. Malone, R. McLaughlin, K. Barry, James A.L. Brown and M. J. Kerin
    Citation: BMC Cancer 2018 18:203
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Cancer 2018 18:282

  38. Even clearly resectable pancreatic cancer still has an unfavorable prognosis. Neoadjuvant or perioperative therapies might improve the prognosis of these patients. Thus, evaluation of perioperative chemotherap...

    Authors: Thomas J. Ettrich, Andreas W. Berger, Lukas Perkhofer, Severin Daum, Alexander König, Andreas Dickhut, Uwe Wittel, Kai Wille, Michael Geissler, Hana Algül, Eike Gallmeier, Jens Atzpodien, Marko Kornmann, Rainer Muche, Nicole Prasnikar, Andrea Tannapfel…
    Citation: BMC Cancer 2018 18:1298
    Content type: Study protocol Published on:

  39. Breast cancer is a global health problem – it is the most common malignancy among women. Triple negative breast cancers (TNBC) account for 10–20% of female breast cancer. Most TNBC cases confer poor prognosis....

    Authors: Tamás Mezei, Melinda Hajdu, Gábor Czigléczki, Gábor Lotz, Judit Kocsis, Janina Kulka and Anna Horváth
    Citation: BMC Cancer 2020 20:615
    Content type: Case report Published on:

  40. Adjuvant therapy improves the prognosis of stage II & III colon cancer patients. Unfortunately, most patients do not benefit from this treatment. PePITA (NCT00994864) is a prospective, multicenter, non-randomi...

    Authors: Françoise Rothé, Marion Maetens, Ghizlane Rouas, Marianne Paesmans, Marc Van den Eynde, Jean-Luc Van Laethem, Philippe Vergauwe, Guido Deboever, Yacine Bareche, Caroline Vandeputte, Michail Ignatiadis and Alain Hendlisz
    Citation: BMC Cancer 2019 19:304
    Content type: Research article Published on:

  41. Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of a...

    Authors: Nadejda Valtcheva, Franziska M. Lang, Aurelia Noske, Eleftherios P. Samartzis, Anna-Maria Schmidt, Elisa Bellini, Daniel Fink, Holger Moch, Markus Rechsteiner, Konstantin J. Dedes and Peter J. Wild
    Citation: BMC Cancer 2017 17:66
    Content type: Case report Published on:

  43. Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) and mitochondria...

    Authors: Xiaoli Li, Yasai Ji, Gaoyang Han, Xiaoran Li, Zhirui Fan, Yaqing Li, Yali Zhong, Jing Cao, Jing Zhao, Mingzhi Zhang, Jianguo Wen, Mariusz Adam Goscinski, Jahn M. Nesland and Zhenhe Suo
    Citation: BMC Cancer 2016 16:894
    Content type: Research article Published on:

  44. Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approa...

    Authors: Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio and Fiona E. Yull
    Citation: BMC Cancer 2022 22:497
    Content type: Research Published on:

  45. There is increasing evidence that the presence of an ongoing systemic inflammatory response is associated with poor prognosis in patients with advanced cancers. We evaluated the relationships between clinical ...

    Authors: Jun-Eul Hwang, Ha-Na Kim, Dae-Eun Kim, Hyun-Jung Choi, Sung-Hoon Jung, Hyun-Jeong Shim, Woo-Kyun Bae, Eu-Chang Hwang, Sang-Hee Cho and Ik-Joo Chung
    Citation: BMC Cancer 2011 11:489
    Content type: Research article Published on:

  46. Inflammatory breast cancer (IBC) had been perceived to have a poor prognosis. Oncologists were not enthusiastic in the past to give aggressive treatment. Single institution studies tend to have small patient n...

    Authors: Patricia Tai, Edward Yu, Ross Shiels, Juan Pacella, Kurian Jones, Evgeny Sadikov and Shazia Mahmood
    Citation: BMC Cancer 2005 5:137
    Content type: Research article Published on:

  47. Intrinsic to "Patient-Centered Care" is being respectful and responsive to individual patient preferences, expressed needs, and personal values. Establishing a patient's preferences for active and aggressive i...

    Authors: Vincent Maida, Jonathan Peck, Marguerite Ennis, Navjot Brar and Alexandria R Maida
    Citation: BMC Cancer 2010 10:592
    Content type: Research article Published on:

  49. For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before su...

    Authors: Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma, Muyasha Abulimiti, Yutong Tan, Feiyan Deng, Wenting Huang, Shuangmei Zou, Wenyan Kang, Liming Jiang, Ying Wang, Chen Hu, Yinggang Chen, Haitao Zhou…
    Citation: BMC Cancer 2024 24:501
    Content type: Study Protocol Published on:

  50. Metastatic breast cancer is a major cause of death among women worldwide; therefore efficient therapeutic strategies are extremely needed. In this work we have developed a gene therapy- and bacteria-based comb...

    Authors: M. Gabriela Kramer, Martín Masner, Erkuden Casales, María Moreno, Cristian Smerdou and José A. Chabalgoity
    Citation: BMC Cancer 2015 15:620
    Content type: Research article Published on:

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