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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. Tumor-infiltrating lymphocytes (TILs) by routine hematoxylin and eosin staining (H&E-TILs) are a robust prognostic biomarker in various cancers. However, the role of H&E-TILs in esophageal squamous cell carcin...

    Authors: Jifang Zheng, Hejun Zhang, Siya Li, Zhaoxin Kang, Fei Zheng, Qiwei Yao, Xueqing Zhang, Ziyi Wu, Jiezhong Wang, Weimin Fang, Jiancheng Li, Gang Chen, Yuangui Chen and Mingqiu Chen
    Citation: BMC Cancer 2023 23:1193
    Content type: Research Published on:

  2. Patients with primary multifocal hepatocellular carcinoma (HCC) have a poor prognosis and often experience a high rate of treatment failure. Multifocal HCC is mainly caused by intrahepatic metastasis (IM), and...

    Authors: Weilong Zou, Zhanjie Fang, Yu Feng, Shangjin Gong, Ziqiang Li, Meng Li, Yong Sun, Xiuyan Ruan, Xiangdong Fang, Hongzhu Qu and Haiyang Li
    Citation: BMC Cancer 2024 24:672
    Content type: Research Published on:

  3. The long-term dynamic recurrence hazard of locally advanced gastric cancer (LAGC) in the clinical setting of adjuvant chemotherapy (ACT) remains unclear.

    Authors: Dong Wu, Jun Lu, Zhen Xue, Qing Zhong, Bin-bin Xu, Hua-Long Zheng, Guo-sheng Lin, Li-li Shen, Jia Lin, Jiao-bao Huang, Davit Hakobyan, Ping Li, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Long-Long Cao…
    Citation: BMC Cancer 2023 23:964
    Content type: Research Published on:

  4. Clinical relevance of tumor infiltrating lymphocytes (TILs) in breast cancer is controversial. Here, we used a tumor microarray including a large series of ductal and lobular breast cancers with long term foll...

    Authors: Raoul Droeser, Inti Zlobec, Ergin Kilic, Uwe Güth, Michael Heberer, Giulio Spagnoli, Daniel Oertli and Coya Tapia
    Citation: BMC Cancer 2012 12:134
    Content type: Research article Published on:

  5. Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase that utilizes collagen as a ligand, is a key molecule in the progression of solid tumors as it regulates the interaction of cancer cells with the ...

    Authors: Hoon Hur, In-Hye Ham, Dakeun Lee, Hyejin Jin, Kristina Y. Aguilera, Hye Jeong Oh, Sang-Uk Han, Ji Eun Kwon, Young-Bae Kim, Ke Ding and Rolf A. Brekken
    Citation: BMC Cancer 2017 17:87
    Content type: Research article Published on:

  6. The VEGF family of ligands and receptors are intimately involved in tumor angiogenesis, lymphangiogenesis and metastasis. The evaluation of VEGF ligand/receptor ratios may provide a more profound understanding...

    Authors: Manuela Eppenberger, Inti Zlobec, Daniel Baumhoer, Luigi Terracciano and Alessandro Lugli
    Citation: BMC Cancer 2010 10:93
    Content type: Research article Published on:

  7. Male breast cancer (MBC) is rare. Given the paucity of randomized trials, treatment is generally extrapolated from female breast cancer guidelines.

    Authors: Piera Gargiulo, Matilde Pensabene, Monica Milano, Grazia Arpino, Mario Giuliano, Valeria Forestieri, Caterina Condello, Rossella Lauria and Sabino De Placido
    Citation: BMC Cancer 2016 16:375
    Content type: Research article Published on:

  8. Merkel cell carcinoma (MCC) is a rare neuroendocrine malignancy of the skin characterized by high aggressiveness. Four main factors are implicated in its development: immunosuppression, ultraviolet radiation, ...

    Authors: Daniele Lavacchi, Stefania Nobili, Marco Brugia, Agnese Paderi, Sara Fancelli, Enrico Caliman, Federica Vergoni and Enrico Mini
    Citation: BMC Cancer 2018 18:1024
    Content type: Case report Published on:

  9. Nuclear factor erythroid 2–related factor 2 (Nrf2) is involved in cell proliferation by promotion of metabolic activity. It is also the major regulator of antioxidants and has a pivotal role in tumor cell prol...

    Authors: Yoshiyuki Yamaguchi, Takao Kamai, Satoru Higashi, Satoshi Murakami, Kyoko Arai, Hiromichi Shirataki and Ken-Ichiro Yoshida
    Citation: BMC Cancer 2019 19:1137
    Content type: Research article Published on:

  10. Although the prognosis of locally advanced cervical cancer has improved dramatically, survival for those with stage IIIB-IVA disease or lymph nodes metastasis remains poor. It is believed that the incorporatio...

    Authors: Gong-yi Zhang, Rong Zhang, Ping Bai, Shu-min Li, Yuan-yuan Zhang, Yi-ran Chen, Man-ni Huang and Ling-ying Wu
    Citation: BMC Cancer 2022 22:1331
    Content type: Research Published on:

  11. Cancer development is mediated by oxidative stress and inflammation, which may correlate with metabolic disorders. The aim of this study was to evaluate antioxidant vitamins status and metabolic parameters in ...

    Authors: Man-Yee Chan, Bor-Jen Lee, Po-Sheng Chang, Han-Yu Hsiao, Li-Ping Hsu, Chia-Hua Chang and Ping-Ting Lin
    Citation: BMC Cancer 2020 20:310
    Content type: Research article Published on:

  12. Platelet distribution width (PDW) and red cell distribution width (RDW) are readily obtainable data, and are reportedly useful as prognostic indicators in some cancers. However, their prognostic significance i...

    Authors: Hiroaki Saito, Shota Shimizu, Yuji Shishido, Kozo Miyatani, Tomoyuki Matsunaga and Yoshiyuki Fujiwara
    Citation: BMC Cancer 2021 21:1317
    Content type: Research Published on:

  14. The chemotherapy resistance and toxicity of chemotherapy are major problems in breast cancer treatment. However, candidate biomarkers for predicting clinical outcomes and better prognosis remain lacking.

    Authors: Lu Chen, Huijie Qi, Liudi Zhang, Haixia Li, Jie Shao, Haifei Chen, Mingkang Zhong, Xiaojin Shi, Ting Ye and Qunyi Li
    Citation: BMC Cancer 2018 18:1038
    Content type: Research article Published on:

  15. Prostate cancer is one of the most commonly diagnosed cancers among men. African Americans (AA) are at an increased risk of developing prostate cancer compared to European Americans (EA). miRNAs play a critica...

    Authors: Marisa Shiina, Yutaka Hashimoto, Priyanka Kulkarni, Pritha Dasgupta, Varahram Shahryari, Soichiro Yamamura, Yuichiro Tanaka and Rajvir Dahiya
    Citation: BMC Cancer 2021 21:1028
    Content type: Research Published on:

  16. An understanding of the nature and magnitude of the impact of cancer is critical to planning how best to deliver supportive care to the growing population of cancer survivors whose need for care may span many ...

    Authors: Allison W Boyes, Afaf Girgis, Catherine D’Este and Alison C Zucca
    Citation: BMC Cancer 2012 12:150
    Content type: Research article Published on:

  19. The incidence of prostate cancer (PCa), the most prevalent malignancy, is currently at the forefront. RNA modification is a subfield of the booming field of epigenetics. To date, more than 170 types of RNA mod...

    Authors: Xuming Zhou, Keqiang Chai, Hezhen Zhu, Cong Luo, Xiaofeng Zou, Junrong Zou and Guoxi Zhang
    Citation: BMC Cancer 2024 24:8
    Content type: Review Published on:

  21. Whether the emotional distress around cancer diagnosis is associated with the long-term outcomes and care utilization is unknown. We aimed to examine the association of mental disorders around cancer diagnosis...

    Authors: Jianwei Zhu, Arvid Sjölander, Katja Fall, Unnur Valdimarsdottir and Fang Fang
    Citation: BMC Cancer 2018 18:322
    Content type: Research article Published on:

  22. Previous researches have reported that tripartite motif-containing 44 (TRIM44) is related to the prognosis of multiple human tumors. This study was designed to systematically assess the prognostic value of TRI...

    Authors: Guoliang Xiao, Qiuxi Yang, Ziwei Bao, Haixia Mao, Yi Zhang and Shibu Lin
    Citation: BMC Cancer 2020 20:525
    Content type: Research article Published on:

  23. Dynapenia is defined as an age-related loss of muscle strength. There is little information on dynapenia in cancer patients and on how it relates to anthropometric variables. The aim of this study was to analy...

    Authors: Ana Beatriz Rechinelli, Isabele Lessa Marques, Eduarda Cristina Rodrigues de Morais Viana, Isadora da Silva Oliveira, Vanusa Felício de Souza, Glenda Blaser Petarli, Jose Luiz Marques Rocha and Valdete Regina Guandalini
    Citation: BMC Cancer 2020 20:1010
    Content type: Research article Published on:

  25. High level of reactive oxygen species (ROS) has been detected in almost all cancers, which make it become one of the best-characterized phenotypes in cancers. Though ROS plays an important role in tumors, the ...

    Authors: Xiangcheng Qing, Deyao Shi, Xiao Lv, Baichuan Wang, Songfeng Chen and Zengwu Shao
    Citation: BMC Cancer 2019 19:997
    Content type: Research article Published on:

  26. MicroRNAs(miRNAs) are small non-coding RNAs that participate in a variety of biologic processes, and dysregulation of miRNA is always associated with cancer development and progression. Aberrant expression of ...

    Authors: Guang-jun Zhang, He Zhou, Hua-xu Xiao, Yu Li and Tong Zhou
    Citation: BMC Cancer 2014 14:109
    Content type: Research article Published on:

  27. Bladder cancer (BLCA) is a common malignant tumor of urinary system with high morbidity and mortality. In recent years, immunotherapy has played a significant role in the treatment of BLCA. Tumor mutation burd...

    Authors: Zhao Zhang, Yongbo Yu, Pengfei Zhang, Guofeng Ma, Mingxin Zhang, Ye Liang, Wei Jiao and Haitao Niu
    Citation: BMC Cancer 2021 21:458
    Content type: Research Published on:

  29. Unresectable esophageal cancer harbors high mortality despite chemoradiotherapy. Better patient selection for more personalized management may result in better treatment outcomes. We presume the ratio of maxim...

    Authors: Po-Jui Chen, Wing-Keen Yap, Yu-Chuan Chang, Chen-Kan Tseng, Yin-Kai Chao, Jason Chia-Hsun Hsieh, Ping-Ching Pai, Ching-Hsin Lee, Chan-Keng Yang, Albert Tsung-Ying Ho and Tsung-Min Hung
    Citation: BMC Cancer 2020 20:545
    Content type: Research article Published on:

  30. Treatment options for pretreated triple-negative breast cancer (TNBC) are limited. This study aimed to evaluate the efficacy and safety of apatinib, an antiangiogenic agent, in combination of etoposide for pre...

    Authors: Mengru Cao, Hailing Lu, Shi Yan, Hui Pang, Lichun Sun, Chunhong Li, Xuesong Chen, Wei Liu, Jing Hu, Jian Huang, Ying Xing, Ningzhi Zhang, Yingqi Chen, Ting He, Danni Zhao, Yuanyuan Sun…
    Citation: BMC Cancer 2023 23:463
    Content type: Research Published on:

  31. Cancer stem cells (CSCs) are implicated in carcinogenesis, cancer progression, and recurrence. Several biomarkers have been described for pancreatic ductal adenocarcinoma (PDAC) CSCs; however, their function a...

    Authors: Jung Hyun Jo, Sun A Kim, Jeong Hoon Lee, Yu Rang Park, Chanyang Kim, Soo Been Park, Dawoon E. Jung, Hee Seung Lee, Moon Jae Chung and Si Young Song
    Citation: BMC Cancer 2021 21:1241
    Content type: Research Published on:

  33. Using a cross-database integrative approach, we performed an epidemiological analysis in a representative region of central Poland to evaluate the availability of radiotherapy (RTx) and overall survival of adu...

    Authors: Justyna Chalubinska-Fendler, Wojciech Fendler, Michal Spych, Jolanta Luniewska-Bury, Wojciech Mlynarski and Jacek Fijuth
    Citation: BMC Cancer 2015 15:214
    Content type: Research article Published on:

  34. The purpose of this study was to determine prognostic factors influencing outcomes of surgical treatment in patients with T4a hypopharyngeal cancer.

    Authors: Sang-Yeon Kim, Young-Soo Rho, Eun-Chang Choi, Min-Sik Kim, Joo-Hyun Woo, Dong Hoon Lee, Eun Jae Chung, Min Woo Park, Da-Hee Kim and Young-Hoon Joo
    Citation: BMC Cancer 2017 17:904
    Content type: Research article Published on:

  35. We aimed to identify tumor-associated antigen (TAA) biomarkers through bioinformatic analysis and experimental verification, and to evaluate a panel of autoantibodies against tumor-associated antigens (TAAbs) ...

    Authors: Weihong Xie, Guiying Sun, Junfen Xia, Huili Chen, Chen Wang, Juan Lin and Peng Wang
    Citation: BMC Cancer 2023 23:802
    Content type: Research Published on:

  36. Stomach cancer is one the most common neoplasms with high mortality. However, fear of cancer recurrence (FCR) in stomach cancer survivors has been scarcely evaluated. Thus, the aim of this study was to evaluat...

    Authors: Jinyoung Shin, Dong Wook Shin, Jungkwon Lee, JiHye Hwang, Ji Eun Lee, BeLong Cho and Yun–Mi Song
    Citation: BMC Cancer 2022 22:414
    Content type: Research article Published on:

  37. Patients with oligometastatic disease can potentially be cured by using an ablative therapy for all active lesions. Stereotactic body radiotherapy (SBRT) is a non-invasive treatment option that lately proved t...

    Authors: Goda G. Kalinauskaite, Ingeborg I. Tinhofer, Markus M. Kufeld, Anne A. Kluge, Arne A. Grün, Volker V. Budach, Carolin C. Senger and Carmen C. Stromberger
    Citation: BMC Cancer 2020 20:404
    Content type: Research article Published on:

  38. Comorbidity has a well documented detrimental effect on cancer survival. However it is difficult to disentangle the direct effects of comorbidity on survival from indirect effects via the influence of comorbid...

    Authors: Diana Sarfati, Sarah Hill, Tony Blakely, Bridget Robson, Gordon Purdie, Elizabeth Dennett, Donna Cormack and Kevin Dew
    Citation: BMC Cancer 2009 9:116
    Content type: Research article Published on:

  39. Gastric cancer is one of the most common tumors worldwide, and most patients are deprived of treatment options when diagnosed at advanced stages. PRDM14 has carcinogenic potential in breast and non-small cell ...

    Authors: Xiao Li, Cong Wang, Youcai Wang, Xiaobing Chen, Zhi Li, Jianwei Wang and Yingjun Liu
    Citation: BMC Cancer 2024 24:685
    Content type: Research Published on:

  40. Since Immune response, nutritional status and Epstein–Barr Virus (EBV) DNA status have been confirmed to be relevant to the prognosis of patients with nasopharyngeal carcinoma (NPC), we believe that the combin...

    Authors: Shuting Wu, Xiaofei Yuan, Haoran Huang, Yanfei Li, Linchong Cui, Danfan Lin, Wenxuan Lu, Huiru Feng, Zilu Chen, Xiong Liu, Jiajie Tan and Fan Wang
    Citation: BMC Cancer 2023 23:1217
    Content type: Research Published on:

  41. Colorectal cancer (CRC) is one of the most common cancers worldwide; it is the fourth leading cause of death in the world and the third in Brazil. Mutations in the APC, DCC, KRAS and TP53 genes have been associat...

    Authors: Aline Simoneti Fonseca, Anelisa Ramão, Matheus Carvalho Bürger, Jorge Estefano Santana de Souza, Dalila Lucíola Zanette, Greice Andreotti de Molfetta, Luiza Ferreira de Araújo, Rafaela de Barros e Lima Bueno, Graziela Moura Aguiar, Jessica Rodrigues Plaça, Cleidson de Pádua Alves, Anemari Ramos Dinarte dos Santos, Daniel Onofre Vidal, Gyl Eanes Barros Silva, Rodrigo Alexandre Panepucci, Fernanda Maris Peria…
    Citation: BMC Cancer 2021 21:207
    Content type: Research article Published on:

  42. Based on the quantitative and qualitative features of CT imaging, a model for predicting the invasiveness of ground-glass nodules (GGNs) was constructed, which could provide a reference value for preoperative ...

    Authors: Yantao Yang, Jing Xu, Wei Wang, Mingsheng Ma, Qiubo Huang, Chen Zhou, Jie Zhao, Yaowu Duan, Jia Luo, Jiezhi Jiang and Lianhua Ye
    Citation: BMC Cancer 2024 24:438
    Content type: Research Published on:

  43. Most clinical trials on colorectal cancer (CRC) exclude cases who have history of a prior malignancy. However, no prior research studied this history’s actual impact on the survival of CRC. In the paper, we st...

    Authors: Muneer J. Al-Husseini, Anas M. Saad, Hadeer H. Mohamed, Mohamad A. Alkhayat, Mohamad Bassam Sonbol and Omar Abdel-Rahman
    Citation: BMC Cancer 2019 19:863
    Content type: Research article Published on:

  44. Higher standardized uptake value (SUV) detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) correlates with proliferation of primary breast cancer. The purpose of th...

    Authors: Shigeto Ueda, Nobuo Kondoh, Hitoshi Tsuda, Souhei Yamamoto, Hideki Asakawa, Kazuhiko Fukatsu, Takayuki Kobayashi, Junji Yamamoto, Katsumi Tamura, Jiro Ishida, Yoshiyuki Abe, Mikio Yamamoto and Hidetaka Mochizuki
    Citation: BMC Cancer 2008 8:384
    Content type: Research article Published on:

  45. Colorectal cancer (CRC) is one of the most common malignances worldwide. Metastasis is responsible for the rapid recurrence and poor prognosis of CRC. However, the underlying molecular mechanism of CRC metasta...

    Authors: Xuehu Xu, Rong Chen, Zhifa Li, Nanqi Huang, Xiaobing Wu, Shuling Li, Yong Li and Shangbiao Wu
    Citation: BMC Cancer 2015 15:1023
    Content type: Research article Published on:

  46. In this era of molecular targeting therapy when various systematic treatments can be selected, prognostic biomarkers are required for the purpose of risk-directed therapy selection. Numerous reports of various...

    Authors: Kazuhiro Namura, Ryogo Minamimoto, Masahiro Yao, Kazuhide Makiyama, Takayuki Murakami, Futoshi Sano, Narihiko Hayashi, Ukihide Tateishi, Hanako Ishigaki, Takeshi Kishida, Takeshi Miura, Kazuki Kobayashi, Sumio Noguchi, Tomio Inoue, Yoshinobu Kubota and Noboru Nakaigawa
    Citation: BMC Cancer 2010 10:667
    Content type: Research article Published on:

  47. Since 1999, patients presenting with brain metastases (BM) from breast cancer (BC) are treated in our institution with a carmustine (BCNU) - methotrexate (MTX) combination. We report here our clinical experien...

    Authors: William Jacot, Marie-Cécile Gerlotto-Borne, Simon Thezenas, Stéphane Pouderoux, Sylvain Poujol, Mahdi About and Gilles Romieu
    Citation: BMC Cancer 2010 10:257
    Content type: Research article Published on:

  48. Several studies have shown that NDRG2 mRNA is down-regulated or undetectable in various human cancers and cancer cell-lines. Although the function of NDRG2 is currently unknown, high NDRG2 expression correlates w...

    Authors: Anders Lorentzen, Rikke H Lewinsky, Jette Bornholdt, Lotte K Vogel and Cathy Mitchelmore
    Citation: BMC Cancer 2011 11:14
    Content type: Research article Published on:

  49. p53R2 is a target of p53 gene, which is essential for DNA repair, mitochondrial DNA synthesis, protection against oxidative stress, chromosomal instability, chronic inflammation and tumorigenesis. This study i...

    Authors: Jiewei Chen, Shuman Li, Yongbo Xiao, Xuan Zou, Xinke Zhang, Mingshu Zhu, Muyan Cai and Dan Xie
    Citation: BMC Cancer 2017 17:846
    Content type: Research article Published on:

  50. Selenium metabolism has been implicated in human health. This study aimed to identify a selenium metabolism regulator-based prognostic signature for hepatocellular carcinoma (HCC) and validate the role of INMT...

    Authors: Huishan Sun, Junyu Long, Bangyou Zuo, Yiran Li, Yu Song, Minghang Yu, Ziyu Xun, Yanyu Wang, Xi Wang, Xinting Sang and Haitao Zhao
    Citation: BMC Cancer 2023 23:451
    Content type: Research Published on:

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