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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

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  1. The dysregulation of gene expression in the TNF-TNFR superfamily has been involved in various human cancers including non-small cell lung cancer (NSCLC). Furthermore, functional polymorphisms in TNF-α and TNFRSF1...

    Authors: Xiaoxiang Guan, Zhongxin Liao, Hongxia Ma, Ji Qian, Zhensheng Liu, Xianglin Yuan, Daniel Gomez, Ritsuko Komaki, Li-E Wang and Qingyi Wei
    Citation: BMC Cancer 2011 11:447
  2. To compare survival of patients with non-small cell lung cancer (NSCLC) who underwent surgical resection and lymph node sampling based on guidelines proposed by the American College of Surgeons Oncology Group ...

    Authors: Dongsheng Yue, Liqun Gong, Jian You, Yanjun Su, Zhenfa Zhang, Zhen Zhang, Feng Gu, Meng Wang and Changli Wang
    Citation: BMC Cancer 2014 14:422
  3. The roles of carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA21-1) and neuron-specific enolase (NSE) in metastases occurrence and poor diagnosis in specific histological classifications of lung ...

    Authors: Li Zhang, Dan Liu, Lei Li, Dan Pu, Ping Zhou, Yuting Jing, He Yu, Yanwen Wang, Yihan Zhu, Yanqi He, Yalun Li, Shuang Zhao, Zhixin Qiu and Weimin Li
    Citation: BMC Cancer 2017 17:96
  4. Lactate dehydrogenase (LDHs) is an enzyme involved in anaerobic glycolysis, including LDHA, LDHB, LDHC and LDHD. Given the regulatory role in the biological progression of certain tumors, we analyzed the role ...

    Authors: Shengnan Wang, Xingwei Wu, Xiaoming Wu, Jin Cheng, Qianyi Chen and Zhilin Qi
    Citation: BMC Cancer 2024 24:156
  5. Sphingosine-1-phosphate receptor (S1PR1) is involved in vascular development, a key process in tumorigenesis. This study aimed to evaluate its roles in tumor development and prognosis.

    Authors: Limei Zhong, Linling Xie, Zhiyong Yang, Lijuan Li, Shaohua Song, Donglin Cao and Yufeng Liu
    Citation: BMC Cancer 2020 20:766
  6. The intratumoral infiltration of T cells, especially memory T cells, is associated with a favorable prognosis in early colorectal cancers. However, the mechanism underlying this process remains elusive. This s...

    Authors: Rui-Qing Peng, Xiao-Jun Wu, Ya Ding, Chun-Yan Li, Xing-Juan Yu, Xing Zhang, Zhi-Zhong Pan, De-Sen Wan, Li-Ming Zheng, Yi-Xin Zeng and Xiao-Shi Zhang
    Citation: BMC Cancer 2010 10:496
  7. The expression of novel oncogenic kinase (NOK), a member of the protein tyrosine kinase (PTK) family, has been observed in several human malignancies including non-small cell lung cancer (NSCLC). However, the ...

    Authors: Peng Chen, Wei-Miao Li, Qiang Lu, Jian Wang, Xiao-Long Yan, Zhi-Pei Zhang and Xiao-Fei Li
    Citation: BMC Cancer 2014 14:402
  8. A secondary malignancy is the most serious complication in lung cancer (LC) survivors. This study aimed to evaluate the clinicopathological features, predictable risk factors and survival of patients with LC w...

    Authors: Huabin Wang, Yin Yin, Ru Wang, Junbin Huang, Hongman Xue, Yucai Cheng, Lidan Zhang and Chun Chen
    Citation: BMC Cancer 2020 20:1081
  9. The aim of this study was to investigate the effects of different thoracic radiotherapy doses on OS and incidence of radiation pneumonia which may provide some basis for optimizing the comprehensive treatment ...

    Authors: Hongyue Qin, Jiaojiao Ke, Shuai Dong, Huani Li, Kunli Zhu, Shuai Fu, Qian Shao and Zhenxiang Li
    Citation: BMC Cancer 2022 22:1012
  10. G-protein inwardly rectifying potassium channel 1 (GIRK1) is thought to play a role in cell proliferation in cancer, and GIRK1 gene expression level may define a more aggressive phenotype. We detected GIRK1 ex...

    Authors: Iwao Takanami, Yoshimasa Inoue and Masatoshi Gika
    Citation: BMC Cancer 2004 4:79
  11. Age is an independent prognostic factor for small cell lung cancer (SCLC). We aimed to construct a nomogram survival prediction for elderly SCLC patients based on the Surveillance, Epidemiology, and End Result...

    Authors: Guangrong Lu, Jiajia Li, Yejiao Ruan, Yuning Shi, Xuchao Zhang, Yushan Xia, Zheng Zhu, Jiafeng Lin and Lili Li
    Citation: BMC Cancer 2022 22:1271
  12. The centromere protein O (CENPO) is an important member of the centromere protein family. However, the role of CENPO in pan–cancer and immune infiltration has not been reported. Here, we investigated the role ...

    Authors: Yuanbiao Wang, Daowen Ye, Ying Li, Fenghong Lv, Wanbo Shen, Hui Li, Linghan Tian, Zongling Fan, Yanling Li, Yan wang, Feng Li and Yan Chen
    Citation: BMC Cancer 2023 23:735
  13. We aimed to examine whether patients with de novo and relapsed/progressed stage IIIB–IV non-small cell lung cancer (NSCLC) without epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK) mutat...

    Authors: Byeong-Chan Oh, Ae-Ryeo Cho, Jin Hyun Nam, So-Young Yang, Min Ji Kim, Sun-Hong Kwon and Eui-Kyung Lee
    Citation: BMC Cancer 2023 23:482
  14. Nomogram is a graphic representation containing the expressed factor of the mathematical formula used to define a particular phenomenon. We aim to build and internally validate a nomogram to predict overall su...

    Authors: Hassan Abdelilah Tafenzi, Farah Choulli, Ganiou Adjade, Anas Baladi, Leila Afani, Mohammed El Fadli, Ismail Essaadi and Rhizlane Belbaraka
    Citation: BMC Cancer 2023 23:1016
  15. Tumour perineural invasion (PNI) is a predictor of poor prognosis, but its effect on the prognosis of patients with colorectal cancer (CRC) has not yet been elucidated.

    Authors: Le Qin, Yixin Heng, Shenghe Deng, Junnan Gu, Fuwei Mao, Yifan Xue, Zhenxing Jiang, Jun Wang, Denglong Cheng, Ke Wu, Yinghao Cao and Kailin Cai
    Citation: BMC Cancer 2023 23:452
  16. Lung cancer is the leading cause of cancer-related deaths worldwide. Early detection is considered critical for lung cancer treatment. MicroRNAs (miRNAs) have shown promise as diagnostic and prognostic indicat...

    Authors: Wangyu Zhu, XiaoGuang Liu, JianYing He, DongDong Chen, YanYan Hunag and Yong Kui Zhang
    Citation: BMC Cancer 2011 11:393
  17. Platinum-based chemoradiotherapy is the standard treatment for unresectable stage III non-small-cell lung cancer (NSCLC). However, few studies have evaluated the efficacy of subsequent chemotherapy for relapse...

    Authors: Eriko Miyawaki, Hirotsugu Kenmotsu, Yasushi Shintani, Ikuo Sekine, Takehito Shukuya, Koichi Takayama, Akira Inoue, Isamu Okamoto, Katsuyuki Kiura, Kazuhisa Takahashi, Nobuyuki Yamamoto, Tomoya Kawaguchi, Etsuo Miyaoka, Ichiro Yoshino and Hiroshi Date
    Citation: BMC Cancer 2022 22:342
  18. The skeletal muscle index (SMI), which is calculated as the ratio of skeletal muscle area at the third lumbar vertebral level divided by height squared, has been considered a prognostic factor in patients with...

    Authors: Masatsugu Amitani, Takaaki Oba, Nami Kiyosawa, Hiroki Morikawa, Tatsunori Chino, Ai Soma, Tadafumi Shimizu, Koichi Ohno, Mayu Ono, Tokiko Ito, Toshiharu Kanai, Kazuma Maeno and Ken-ichi Ito
    Citation: BMC Cancer 2022 22:327
  19. A major obstacle in treating colorectal cancer (CRC) is the acquired resistance to chemotherapeutic agents. An important protein in the regulation of cancer cell death and clinical outcome is Raf kinase inhibi...

    Authors: Sam Cross-Knorr, Shaolei Lu, Kimberly Perez, Sara Guevara, Kate Brilliant, Claudio Pisano, Peter J Quesenberry, Murray B Resnick and Devasis Chatterjee
    Citation: BMC Cancer 2013 13:463
  20. Pleural invasion (PL) has been regarded as an unfavorable prognostic factor for non-small cell lung cancer (NSCLC). But there was no agreement on the optimal surgical extent in NSCLC patients with PL. We aimed...

    Authors: Xue Song, Yangyang Xie, Yurou Zhu and Yafang Lou
    Citation: BMC Cancer 2022 22:541
  21. There is a paucity of data regarding the prognostic influence of peripheral blood CD4+ T lymphopenia in non-small cell lung cancer (NSCLC). Therefore, we investigated the prognostic value of T lymphopenia in N...

    Authors: Guillaume Eberst, Dewi Vernerey, Caroline Laheurte, Aurélia Meurisse, Vincent Kaulek, Laurie Cuche, Pascale Jacoulet, Hamadi Almotlak, Jean Lahourcade, Marie Gainet-Brun, Elizabeth Fabre, Françoise Le Pimpec-Barthes, Olivier Adotevi and Virginie Westeel
    Citation: BMC Cancer 2022 22:529
  22. Lung cancer incidence and prevalence is increasing worldwide and there is a focus on prevention, early detection, and development of new treatments which will impact the epidemiological patterns of lung cancer...

    Authors: Erik Jakobsen, Karen Ege Olsen, Mette Bliddal, Malene Hornbak, Gitte F. Persson and Anders Green
    Citation: BMC Cancer 2021 21:985
  23. Circulating baseline levels of the plasma-protein osteopontin (OPN) have been suggested as a prognostic indicator in chemotherapy and surgery for lung cancer. However, the role of this hypoxia-related protein ...

    Authors: Christian Ostheimer, Matthias Bache, Antje Güttler, Thomas Reese and Dirk Vordermark
    Citation: BMC Cancer 2014 14:858
  24. The CSC (cancer stem cell) markers often indicate poor prognosis and more cell invasion or migration of cancer patients. Podoplanin was assumed as a candidate CSC marker and predict poor prognosis among squamo...

    Authors: Liya Hu, Peng Zhang, Qi Mei, Wei Sun, Lei Zhou and Tiejun Yin
    Citation: BMC Cancer 2020 20:424
  25. To assess the clinical characteristics and the risk factors related to the unfavorable prognosis of endometrioid ovarian carcinoma (EOVC) based on data from the Surveillance, Epidemiology, and End Results (SEE...

    Authors: Shuangfeng Chen, Huaiwu Lu, Shan Jiang, Min Li, Haiyan Weng, Jing Zhu, Tianjiao Zhang, Yingying Wang, Weidong Zhao, Dabao Wu, Zhen Shen, Zhenye Yang and Ying Zhou
    Citation: BMC Cancer 2023 23:608
  26. Survival rates of lung cancer remains poor and the impact of comorbidities on the prognosis is discussed. The objective of this study was to assess if the Charlson Comorbidity Index (CCI) was associated with 8...

    Authors: A. Seigneurin, P. Delafosse, B. Trétarre, A. S. Woronoff, M. Velten, P. Grosclaude, A. V. Guizard, B. Lapôtre-Ledoux, S. Bara, F. Molinié and M. Colonna
    Citation: BMC Cancer 2018 18:1091
  27. The purpose of this study was to explore clinicalpathology features, molecular features and outcome of male breast cancer patients who expressed ER, PR as well as HER-2, namely triple-positive male breast canc...

    Authors: Biyuan Wang, Hui Wang, Andi Zhao, Mi Zhang and Jin Yang
    Citation: BMC Cancer 2021 21:523
  28. The neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) are associated with poor prognoses in patients with gastric cancer; however, few studies have focused on the dynamic changes ...

    Authors: Mikito Mori, Kiyohiko Shuto, Chihiro Kosugi, Kazuo Narushima, Hideki Hayashi, Hisahiro Matsubara and Keiji Koda
    Citation: BMC Cancer 2018 18:1261
  29. The expression and activation of eukaryotic translation initiation factor 4E (eIF4E) is associated with cell transformation and tumor initiation, but the functional role and the mechanism whereby it drives imm...

    Authors: Fan Li, Huizhi Sun, Yue Li, Xiaoyu Bai, Xueyi Dong, Nan Zhao, Jie Meng, Baocun Sun and Danfang Zhang
    Citation: BMC Cancer 2021 21:1305
  30. The current standard postoperative treatment for stage II-IIIA non-small cell lung cancer (NSCLC) is a regimen of platinum doublet adjuvant chemotherapy. These regimens, which are the same as for solid NSCLC t...

    Authors: Tomoshi Tsuchiya, Keitaro Matsumoto, Takuro Miyazaki, Ryoichiro Doi, Shoji Tokunaga, Hiroyuki Yamaguchi, Koichi Tomoshige, Hironosuke Watanabe, Takeshi Nagayasu and Kenji Sugio
    Citation: BMC Cancer 2021 21:249
  31. Lung cancer is the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. In traditional anti-cancer therapy, epidermal growth factor recep...

    Authors: Hao Gong, Yongwen Li, Yin Yuan, Weiting Li, Hongbing Zhang, Zihe Zhang, Ruifeng Shi, Minghui Liu, Chao Liu, Chen Chen, Hongyu Liu and Jun Chen
    Citation: BMC Cancer 2020 20:1189
  32. Human epidermal growth factor receptor-2 (HER2) is a transmembrane tyrosine kinase receptor that is overexpressed in 25 to 30 % of human breast cancers and is preferentially localized in lipid rafts. Stomatin ...

    Authors: Chin-Yau Chen, Chih-Yung Yang, Yen-Chung Chen, Chia-Wen Shih, Su-Shun Lo and Chi-Hung Lin
    Citation: BMC Cancer 2016 16:697
  33. Although many studies have explored the correlation between quality of life and survival, none have reported this relationship for specific cancers assessed at distinct time points. This meta-analysis aimed to...

    Authors: Taro Okayama, Katsuyoshi Suzuki, Shinichiro Morishita, Junichiro Inoue, Takashi Tanaka, Jiro Nakano and Takuya Fukushima
    Citation: BMC Cancer 2024 24:495

    The Correction to this article has been published in BMC Cancer 2024 24:529

  34. Bladder cancer (BLCA) is one of the most common genitourinary malignancies in the world, but its pathogenic genes have not been fully identified and the treatment outcomes are still unsatisfactory. Although th...

    Authors: Lijuan Gao, Ruimin Ren, Jing Shen, Jiayi Hou, Junya Ning, Yanlin Feng, Meiyue Wang, Lifei Wu, Yaojun Sun, Huang Wang, Deping Wang and Jimin Cao
    Citation: BMC Cancer 2022 22:1016
  35. The recurrence site that influences post-recurrence survival (PRS) in patients with non-small cell lung cancer (NSCLC) undergoing surgery and the preoperative predictors of recurrence remain unclear.

    Authors: Tetsuya Isaka, Hiroyuki Adachi, Kotaro Murakami, Jun Miura, Noritake Kikunishi, Naoko Shigeta, Yujin Kudo, Yoshihiro Miyata, Morihito Okada, Norihiko Ikeda and Hiroyuki Ito
    Citation: BMC Cancer 2023 23:1064
  36. Identification of patient-related factors associated with Health-Related Quality of Life (HRQoL) and Quality of Life (QoL) at the start of treatment may identify patients who are prone to a decrease in HRQoL a...

    Authors: Mark de Mol, Sabine Visser, Joachim Aerts, Paul Lodder, Nico van Walree, Huub Belderbos and Brenda den Oudsten
    Citation: BMC Cancer 2020 20:431
  37. Psoriasin (S100A7) is a member of the S100 gene family. Alteration of Psoriasin expression has previously been reported to play an important role in cancer aggressive behaviour. The current study sought to inv...

    Authors: Mu Hu, Lin Ye, Fiona Ruge, Xiuyi Zhi, Lijian Zhang and Wen G Jiang
    Citation: BMC Cancer 2012 12:588
  38. Cancer-testis antigens (CTAs) have emerged as potential clinical biomarkers targeting immunotherapy. KK-LC-1 is a member of CTAs, which has been demonstrated in a variety of tumors tissues and been found to el...

    Authors: Yanli Kang, Yuhan Gan, Yingfeng Jiang, Jianbin You, Chen Huang, Qianshun Chen, Xunyu Xu, Falin Chen and Liangyuan Chen
    Citation: BMC Cancer 2022 22:834
  39. Cancer of unknown primary site(CUPs) is a metastatic syndrome with an unidentifiable primary tumor, even after extensive workup to seek the primary site. CUPs accounts for about 3%-5% of the total number of al...

    Authors: HongLiang Yang, Feng He, Wen Xu and Zeng Cao
    Citation: BMC Cancer 2022 22:1372
  40. Tumor recurrence and metastasis are the most common reason for treatment failure. Metastasis-associate in colon cancer-1 (MACC1) has been identified as a metastatic and prognostic biomarker for colorectal canc...

    Authors: Lei Zhou, Lan Yu, Bo Zhu, Shiwu Wu, Wenqing Song, Xiaomeng Gong and Danna Wang
    Citation: BMC Cancer 2016 16:876
  41. This study aimed to establish a novel nomogram prognostic model to predict death probability for non-small cell lung cancer (NSCLC) patients who received surgery..

    Authors: Bo Jia, Qiwen Zheng, Jingjing Wang, Hongyan Sun, Jun Zhao, Meina Wu, Tongtong An, Yuyan Wang, Minglei Zhuo, Jianjie Li, Xue Yang, Jia Zhong, Hanxiao Chen, Yujia Chi, Xiaoyu Zhai and Ziping Wang
    Citation: BMC Cancer 2020 20:666
  42. This study systematically reviewed the evidence on the influence of stigma and nihilism on lung cancer patterns of care; patients’ psychosocial and quality of life (QOL) outcomes; and how this may link to publ...

    Authors: Suzanne K Chambers, Jeffrey Dunn, Stefano Occhipinti, Suzanne Hughes, Peter Baade, Sue Sinclair, Joanne Aitken, Pip Youl and Dianne L O’Connell
    Citation: BMC Cancer 2012 12:184
  43. For the first-line treatment of KRAS mutant non-small cell lung cancer (NSCLC) patients, immunotherapy or platinum-based chemotherapy are the main treatment method. Here, we investigated the clinical efficacy ...

    Authors: Yanxia Liu, Yuan Gao, Ying Wang, Cong Zhao, Zhiyun Zhang, Baolan Li and Tongmei Zhang
    Citation: BMC Cancer 2022 22:1175
  44. Uncontrolled proliferation and increased motility are hallmarks of neoplastic cells, therefore markers of proliferation and motility may be valuable in assessing tumor progression and prognosis. MCM2 is a memb...

    Authors: Jun Yang, Nithya Ramnath, Kirsten B Moysich, Harold L Asch, Helen Swede, Sadir J Alrawi, Joel Huberman, Joseph Geradts, John SJ Brooks and Dongfeng Tan
    Citation: BMC Cancer 2006 6:203
  45. Radical resection plus lymph node dissection is a common treatment for patients with T1-3N0M0 non-small cell lung cancer (NSCLC). Few models predicted the survival outcomes of these patients. This study aimed to ...

    Authors: Weijian Mei, Wang Yao, Zhengbo Song, Wenjie Jiao, Lianxin Zhu, Qinghua Huang, Chaolun An, Jianguang Shi, Guiping Yu, Pingli Sun, Yinbin Zhang, Jianfei Shen, Chunwei Xu, Han Yang, Qian Wang and Zhihua Zhu
    Citation: BMC Cancer 2023 23:715
  46. In 1997, the Radiation Therapy Oncology Group (RTOG) put forward the recursive partitioning analysis classification for the prognosis of brain metastases (BMs), but this system does not take into account the epid...

    Authors: Jing Wang, Zhiyan Liu, Qingsong Pang, Tian Zhang, Xi Chen, Puchun Er, Yuwen Wang, Ping Wang and Jun Wang
    Citation: BMC Cancer 2020 20:837
  47. CD44s is a cell adhesion molecule known to mediate cellular adhesion to the extracellular matrix, a prerequisite for tumor cell migration. CD44s plays an important role in invasion and metastasis of various ca...

    Authors: Yoon Ho Ko, Hye Sung Won, Eun Kyoung Jeon, Sook Hee Hong, Sang Young Roh, Young Seon Hong, Jae Ho Byun, Chan-Kwon Jung and Jin Hyoung Kang
    Citation: BMC Cancer 2011 11:340

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