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3909 result(s) for 'lung cancer prognosis stage 4' within BMC Cancer

Page 17 of 79

  1. Precision medicine highlights the importance of incorporating molecular genetic testing into standard clinical care. Next-generation sequencing can detect cancer-specific gene mutations, and molecular-targeted...

    Authors: Huita Wu, Haonan Ji, Wenhui Yang, Min Zhang, Yifang Guo, Bangkai Li, Jiayin Wang, Rongrong Chen, Yuan Chen and Xin Wang
    Citation: BMC Cancer 2022 22:1020
    Content type: Research Published on:

  2. Local ablative therapy (LAT) may be beneficial for patients with epidermal growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) with oligo-residual disease after treatment with EGFR tyrosine k...

    Authors: Taichi Miyawaki, Hirotsugu Kenmotsu, Hiroaki Kodama, Naoya Nishioka, Eriko Miyawaki, Nobuaki Mamesaya, Haruki Kobayashi, Shota Omori, Ryo Ko, Kazushige Wakuda, Akira Ono, Tateaki Naito, Haruyasu Murakami, Keita Mori, Hideyuki Harada, Masahiro Endo…
    Citation: BMC Cancer 2021 21:1247
    Content type: Research Published on:

  3. Nonerythrocytic spectrin beta 1 (SPTBN1) is an important cytoskeletal protein that involves in normal cell growth and development via regulating TGFβ/Smad signaling pathway, and is aberrantly expressed in vari...

    Authors: Wenting Tang, Qiong Shao, Zhanwen He, Xu Zhang, Xiaojuan Li and Ruohao Wu
    Citation: BMC Cancer 2023 23:303
    Content type: Research Published on:

  4. Immune-related genes is closely related to the occurrence and prognosis of head and neck squamous cell carcinoma (HNSCC). At the same time, immune-related genes have great potential as prognostic markers in ma...

    Authors: Fujun Zhang, Yu Liu, Yixin Yang and Kai Yang
    Citation: BMC Cancer 2020 20:1015
    Content type: Research article Published on:

  5. Na+/H+ exchanger regulatory factor 1 (NHERF1) is an important scaffold protein participates in the modulation of a variety of intracellular signal pathways. NHERF1 was able to enhance the effects of chemo-drugs i...

    Authors: Fenglian Yang, Mu Hu, Siyuan Chang, Jing Huang, Yang Si, Jinghui Wang, Shan Cheng and Wen G. Jiang
    Citation: BMC Cancer 2020 20:202
    Content type: Research article Published on:

  6. The effective treatment and prognosis prediction of bladder cancer (BLCA) remains a medical problem. Ferroptosis is an iron-dependent form of programmed cell death. Ferroptosis is closely related to tumour occ...

    Authors: Yingchun Liang, Fangdie Ye, Chenyang Xu, Lujia Zou, Yun Hu, Jimeng Hu and Haowen Jiang
    Citation: BMC Cancer 2021 21:943
    Content type: Research Published on:

  7. The combined application of immune cells and specific biomarkers related to the tumor immune microenvironment has a better predictive value for the prognosis of HCC. The purpose of this study is to construct a...

    Authors: Youpeng Wang, Yeni Yang, Ziyin Zhao, Hongfa Sun, Dingan Luo, Lakshmi Huttad, Bingyuan Zhang and Bing Han
    Citation: BMC Cancer 2022 22:379
    Content type: Research Published on:

  8. There is strong evidence demonstrating that activation of epidermal growth factor receptors (EGFRs) leads to tumor growth, progression, invasion and metastasis. Erlotinib and gefitinib, two EGFR-targeted agent...

    Authors: Roque Diaz, Paul A Nguewa, Ricardo Parrondo, Carlos Perez-Stable, Irene Manrique, Miriam Redrado, Raul Catena, Maria Collantes, Ivan Peñuelas, Juan Antonio Díaz-González and Alfonso Calvo
    Citation: BMC Cancer 2010 10:188
    Content type: Research article Published on:

  9. Advanced lung cancer patients face significant physical and psychological burden leading to reduced physical function and quality of life. Separately, physical activity, nutrition, and palliative symptom manag...

    Authors: Manuel Ester, S. Nicole Culos-Reed, Amane Abdul-Razzak, Julia T. Daun, Delaney Duchek, George Francis, Gwyn Bebb, Jennifer Black, Audra Arlain, Chelsia Gillis, Lyle Galloway and Lauren C. Capozzi
    Citation: BMC Cancer 2021 21:159
    Content type: Research article Published on:

  10. Lung cancer significantly impairs exercise capacity and health-related quality of life (HRQL). Pulmonary rehabilitation (PR) has demonstrated positive effects on exercise capacity and HRQL in lung cancer patie...

    Authors: Chun-Yao Huang, Min-Shiau Hsieh, Po-Chun Hsieh, Yao-Kuang Wu, Mei-Chen Yang, Shiang-Yu Huang, I-Shiang Tzeng and Chou-Chin Lan
    Citation: BMC Cancer 2024 24:211
    Content type: Research Published on:

  11. Despite significant advances in staging and therapies, lung cancer remains a major cause of cancer-related lethality due to its high incidence and recurrence. Clearly, a novel approach is required to develop n...

    Authors: Norashikin Zakaria, Narazah Mohd Yusoff, Zubaidah Zakaria, Moon Nian Lim, Puteri J Noor Baharuddin, Kamal Shaik Fakiruddin and Badrul Yahaya
    Citation: BMC Cancer 2015 15:84
    Content type: Research article Published on:

  13. The VeriStrat test is a serum proteomic signature originally discovered in non-responders to second line gefitinib treatment and subsequently used to predict differential benefit from erlotinib versus chemothe...

    Authors: Mary Jo Fidler, Cristina L. Fhied, Joanna Roder, Sanjib Basu, Selina Sayidine, Ibtihaj Fughhi, Mark Pool, Marta Batus, Philip Bonomi and Jeffrey A. Borgia
    Citation: BMC Cancer 2018 18:310
    Content type: Research article Published on:

  14. Axitinib is an orally active and potent tyrosine kinase inhibitor of vascular endothelial growth factor receptors 1, 2 and 3. This phase II study assessed the efficacy and safety of axitinib combined with cisp...

    Authors: Igor M Bondarenko, Antonella Ingrosso, Paul Bycott, Sinil Kim and Cristina L Cebotaru
    Citation: BMC Cancer 2015 15:339
    Content type: Research article Published on:

  15. Behind breast, colorectal, and lung cancers, cervical cancer is the fourth most common cancer affecting females. Despite, it is a preventable form of cancer both the incidence and mortality figures reflect it ...

    Authors: Amare Zewdie, Solomon Shitu, Natnael Kebede, Anteneh Gashaw, Habitu Birhan Eshetu, Tenagnework Eseyneh and Abebaw Wasie Kasahun
    Citation: BMC Cancer 2023 23:1228
    Content type: Research Published on:

  16. Immune checkpoint inhibitors (ICI) either alone or in combination with chemotherapy have expanded our choice of agents for the palliative treatment of non-small cell lung cancer (NSCLC) patients. Unfortunately...

    Authors: Wolfgang M. Brueckl, Joachim H. Ficker and Gloria Zeitler
    Citation: BMC Cancer 2020 20:1185
    Content type: Review Published on:

  17. Current guidelines only propose the importance of perineural invasion(PNI) on prognosis in stage II colon cancer. However, the prognostic value of PNI in other stages of colorectal cancer (CRC) is ambiguous.

    Authors: Bin Zhang, Yanyun Lin, Chao Wang, Zexian Chen, Tianze Huang, Hao Chen, Guannan Wang, Ping Lan, Xiaowen He and Xiaosheng He
    Citation: BMC Cancer 2023 23:675
    Content type: Research Published on:

  18. The treatment of choice for advanced non–small cell lung cancer is selected according to the presence of specific alterations. Patients should undergo molecular testing for relevant modifications and the mutat...

    Authors: Luciene Schluckebier, Rosangela Caetano, Osvaldo Ulises Garay, Giuliana T. Montenegro, Marcelo Custodio, Veronica Aran and Carlos Gil Ferreira
    Citation: BMC Cancer 2020 20:875
    Content type: Research article Published on:

  19. Little is known on the relationship between the expression of pyroptosis related genes (PRGs) and prognosis of hepatocellular carcinoma (HCC). In this study, a specific PRGs prognostic model was developed with...

    Authors: Guoxu Fang, Qinghua Zhang, Jianhui Fan, Haitao Li, Zongren Ding, Jun Fu, Yijun Wu, Yongyi Zeng and Jingfeng Liu
    Citation: BMC Cancer 2022 22:999
    Content type: Research Published on:

  20. The prognosis of non-small-cell lung cancer (NSCLC) with brain metastases is very poor. Currently, therapeutic methods for this patient population include whole-brain radiation therapy (WBRT), surgery, radiosu...

    Authors: Kejun Liu, Guanming Jiang, Ailing Zhang, Zhuanghua Li and Jun Jia
    Citation: BMC Cancer 2020 20:76
    Content type: Research article Published on:

  21. Regorafenib has shown promising results as a second-line therapy for patients with hepatocellular carcinoma (HCC) who progressed on sorafenib. Although there have been several data regarding the efficacy of se...

    Authors: Young Mi Hong, K. T. Yoon and Mong Cho
    Citation: BMC Cancer 2021 21:569
    Content type: Research article Published on:

  22. The system L amino acid transporter (LAT) has an important role in the transport of various amino acids, and there have been reports about the relation of this system to cancer. Although LATs are highly expres...

    Authors: Hironori Betsunoh, Takehiko Fukuda, Naohiko Anzai, Daisaku Nishihara, Tomoya Mizuno, Hideo Yuki, Akinori Masuda, Yoshiyuki Yamaguchi, Hideyuki Abe, Masahiro Yashi, Yoshitatsu Fukabori, Ken-Ichiro Yoshida and Takao Kamai
    Citation: BMC Cancer 2013 13:509
    Content type: Research article Published on:

  23. The screening of ROS proto-oncogene 1, receptor tyrosine kinase(ROS1) fusion rearrangement might be potentially beneficial for an effective therapy against non-small cell lung cancer (NSCLC). However, the thre...

    Authors: Jieyu Wu, Yunen Lin, Xinming He, Haihong Yang, Ping He, Xinge Fu, Guangqiu Li and Xia Gu
    Citation: BMC Cancer 2016 16:599
    Content type: Research article Published on:

  24. In nasopharyngeal cancer (NPC), women have a lower incidence and mortality rate than men. Whether sex influences the prognosis of NPC patients remains debatable. We retrospectively examined the influence of se...

    Authors: Linchong Cui, Zilu Chen, Fangfang Zeng, Xiaolan Jiang, Xiaoyan Han, Xiaofei Yuan, Shuting Wu, Huiru Feng, Danfan Lin, Wenxuan Lu, Xiong Liu, Xiaohong Peng and Bolong Yu
    Citation: BMC Cancer 2023 23:1146
    Content type: Research Published on:

  25. Cholangiocarcinoma (CCA) is an aggressive solid tumour with a 5-year survival rate ranging from 7% to 20%. It is, therefore, urgent to identify novel biomarkers and therapeutic targets to improve the outcomes ...

    Authors: Zuyi Ma, Tiange Xie, Jia Sun, Jianchun Yu, Shanzhou Huang, Qi Zhou and Binglu Li
    Citation: BMC Cancer 2023 23:404
    Content type: Research Published on:

  26. Lung squamous cell carcinoma (LSCC) remains a challenging disease to treat, and further improvements in prognosis are dependent upon the identification of LSCC-specific therapeutic biomarkers and/or targets. W...

    Authors: Erkhem-Ochir Bilguun, Kyoichi Kaira, Reika Kawabata-Iwakawa, Susumu Rokudai, Kimihiro Shimizu, Takehiko Yokobori, Tetsunari Oyama, Ken Shirabe and Masahiko Nishiyama
    Citation: BMC Cancer 2020 20:935
    Content type: Research article Published on:

  27. Human epidermal growth factor receptor (HER)-2 is a driver gene in non-small cell lung cancer (NSCLC). The present study evaluated the mutation rate of HER-2 within the wild-type epidermal growth factor receptor ...

    Authors: Xuefei Li, Chao Zhao, Chunxia Su, Shengxiang Ren, Xiaoxia Chen and Caicun Zhou
    Citation: BMC Cancer 2016 16:828
    Content type: Research article Published on:

  28. Recurrences are the main reasons for unfavorable outcomes for patients with stage II colorectal cancer (CRC). To obtain a clear understanding of the high-risk factors, further investigation is warranted. The p...

    Authors: Zhi-Zhong Xiong, Ming-Hao Xie, Xian-Zhe Li, Long-Yang Jin, Feng-Xiang Zhang, Shi Yin, Hua-Xian Chen and Lei Lian
    Citation: BMC Cancer 2023 23:658
    Content type: Research article Published on:

  29. The need for novel biomarkers that could aid in non-small cell lung cancer (NSCLC) detection, together with the relevance of Matrix Metalloproteases (MMPs) -1, -2, -7, -9 and -10 in lung tumorigenesis, prompte...

    Authors: Sonia Blanco-Prieto, Leticia Barcia-Castro, María Páez de la Cadena, Francisco Javier Rodríguez-Berrocal, Lorena Vázquez-Iglesias, María Isabel Botana-Rial, Alberto Fernández-Villar and Loretta De Chiara
    Citation: BMC Cancer 2017 17:823
    Content type: Research article Published on:

  30. Clear cell renal cell carcinoma (ccRCC) is one of the most lethal urological malignancies, but the pathogenesis and prognosis of ccRCC remain obscure, which need to be better understand.

    Authors: Yang Dong, Wei-ming Ma, Wen Yang, Lin Hao, Shao-qi Zhang, Kun Fang, Chun-hui Hu, Qian-jin Zhang, Zhen-duo Shi, Wen-da Zhang, Tao Fan, Tian Xia and Cong-hui Han
    Citation: BMC Cancer 2021 21:1135
    Content type: Research Published on:

  31. Cancer serum protein profiling by mass spectrometry has uncovered mass profiles that are potentially diagnostic for several common types of cancer. However, direct mass spectrometric profiling has a limited dy...

    Authors: Wei-Min Gao, Rork Kuick, Randal P Orchekowski, David E Misek, Ji Qiu, Alissa K Greenberg, William N Rom, Dean E Brenner, Gilbert S Omenn, Brian B Haab and Samir M Hanash
    Citation: BMC Cancer 2005 5:110
    Content type: Research article Published on:

  32. Lung cancer is one of the leading causes of death in Europe and the western world. At present, diagnosis of lung cancer very often happens late in the course of the disease since inexpensive, non-invasive and ...

    Authors: Amel Bajtarevic, Clemens Ager, Martin Pienz, Martin Klieber, Konrad Schwarz, Magdalena Ligor, Tomasz Ligor, Wojciech Filipiak, Hubert Denz, Michael Fiegl, Wolfgang Hilbe, Wolfgang Weiss, Peter Lukas, Herbert Jamnig, Martin Hackl, Alfred Haidenberger…
    Citation: BMC Cancer 2009 9:348
    Content type: Research article Published on:

  33. Osteosarcoma is an aggressive malignant bone sarcoma worldwide. A causal gene network with specific functions underlying both the development and progression of OS was still unclear. Here we firstly identified...

    Authors: Jiahua Li, Hui Shi, Zhanyuan Yuan, Zhiheng Wu, Haohao Li, Yuelong Liu, Ming Lu and Ming Lu
    Citation: BMC Cancer 2022 22:108
    Content type: Research Published on:

  34. The prognostic value of cytokeratin 19 fragment (CYFRA 21 − 1) and Ki67 in advanced non-small cell lung cancer (NSCLC) patients with wild-type epidermal growth factor receptor (EGFR) remains to be explored.

    Authors: Tao Li, Qi Xie, Yang-Yang Fang, Yi Sun, Xiao Ming Wang, Zhu Luo, Gui-Ling Yan, Jian-Bo He and Xiao-Qun Zheng
    Citation: BMC Cancer 2023 23:295
    Content type: Research Published on:

  35. Tumor microenvironment (TME) is of great importance to regulate the initiation and advance of cancer. The immune infiltration patterns of TME have been considered to impact the prognosis and immunotherapy sens...

    Authors: Yinghe Ding, Ling Chu, Qingtai Cao, Hanyu Lei, Xinyu Li and Quan Zhuang
    Citation: BMC Cancer 2023 23:45
    Content type: Research Published on:

  36. Various studies have reported that the neutrophil-to-lymphocyte ratio in the serum (sNLR) may serve as a cost-effective and useful prognostic factor in patients with various cancer types. However, no study has...

    Authors: Yong Seok Lee, Hae-Seong Nam, Jun Hyeok Lim, Jung Soo Kim, Yeonsook Moon, Jae Hwa Cho, Jeong-Seon Ryu, Seung Min Kwak and Hong Lyeol Lee
    Citation: BMC Cancer 2017 17:557
    Content type: Research article Published on:

  37. Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and in China. We know miRNAs influence gene expression in tumorigenesis, but it is unclear how miRNAs affect gene expressi...

    Authors: Howard Yang, Hua Su, Nan Hu, Chaoyu Wang, Lemin Wang, Carol Giffen, Alisa M. Goldstein, Maxwell P. Lee and Philip R. Taylor
    Citation: BMC Cancer 2020 20:388
    Content type: Research article Published on:

  38. An increasing amount of research has speculated that necroptosis could be a therapeutic strategy for treating cancer. However, understanding the prognostic value of the necroptosis-related long non-coding RNAs...

    Authors: Jianlan Liu, Binlin Luo, Pengpeng Zhang, Keyu Jiang, Zuoqiong Hou, Xiaojian Cao and Jian Tang
    Citation: BMC Cancer 2023 23:752
    Content type: Research Published on:

  39. Several studies have demonstrated that the preoperative Glasgow prognostic score (GPS) and modified GPS (mGPS) reflected the prognosis in patients undergoing curative surgery for colorectal cancer. However, th...

    Authors: Kenta Kasahara, Masanobu Enomoto, Ryutaro Udo, Tomoya Tago, Junichi Mazaki, Tetsuo Ishizaki, Tesshi Yamada, Yuichi Nagakawa, Kenji Katsumata and Akihiko Tsuchida
    Citation: BMC Cancer 2022 22:20
    Content type: Research Published on:

  40. Transmembrane protein 180 (TMEM180) is a newly identified colorectal cancer (CRC)-specific molecule that is expressed very rarely in normal tissue and up-regulated under hypoxic conditions. We developed a mono...

    Authors: Takuya Shiraishi, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa, Takeshi Sasaki, Masaaki Ito, Motohiro Kojima, Genichiro Ishii, Ryo Tsumura, Sinji Saijou, Yoshikatsu Koga, Masahiro Yasunaga and Yasuhiro Matsumura
    Citation: BMC Cancer 2021 21:302
    Content type: Research article Published on:

  41. Recent studies have suggested the important roles of CD47 and tumor-associated macrophages in the prognosis and immunotherapy of various human malignancies. However, the clinical significance of CD47 expressio...

    Authors: Rami Imam, Qing Chang, Margaret Black, Caroline Yu and Wenqing Cao
    Citation: BMC Cancer 2021 21:320
    Content type: Research article Published on:

  42. To analyze the expression of karyopherin alpha 2 (KPNA2) in upper tract urothelial carcinoma (UTUC) and to investigate whether the KPNA2 expression provides additional prognostic information following radical ...

    Authors: Bentao Shi, Boxing Su, Dong Fang, Yuan Tang, Gengyan Xiong, Zhongqiang Guo, Qun He, Xinyu Yang, Wei Zhao, Yinglu Guo, Xuesong Li and Liqun Zhou
    Citation: BMC Cancer 2015 15:380
    Content type: Research article Published on:

  43. This study aims to evaluate the clinical efficacy and side effects of setting up a high-risk clinical target volume (CTV-hr) alongside simultaneous integrated boost intensity-modulated radiotherapy (IMRT-SIB) ...

    Authors: Yuqi Jiang, Jing Wang, Peng Jiang, Xiang Wang, Lei Zhang and Yongchun Zhang
    Citation: BMC Cancer 2023 23:481
    Content type: Research Published on:

  44. Response Evaluation Criteria in Solid Tumors (RECIST) are widely used to assess the effect of chemotherapy in patients with cancer. We hypothesised that the change in unidimensional tumour size handled as a co...

    Authors: Anne-Claire Toffart, Denis Moro-Sibilot, Sébastien Couraud, Patrick Merle, Maurice Perol, Nicolas Girard, Pierre-Jean Souquet, Bénédicte Mastroianni, Gilbert R Ferretti, Philippe Romand, Patrick Chatellain, Aurélien Vesin, Elisabeth Brambilla, Christian Brambilla and Jean-François Timsit
    Citation: BMC Cancer 2014 14:989
    Content type: Research article Published on:

  45. In Non-small cell lung cancer (NSCLC), an overactive epidermal growth factor receptor (EGFR) pathway is a component of the malignant phenotype. Two tyrosine kinase inhibitors (TKIs) of EGFR, gefinitib and erlo...

    Authors: Ivette F Emery, Chiara Battelli, Paul L Auclair, Kathleen Carrier and Daniel M Hayes
    Citation: BMC Cancer 2009 9:333
    Content type: Research article Published on:

  46. Lung cancer is a leading cause of cancer-related mortality worldwide, and effective therapies are limited. Lung cancer is a leading cause of cancer-related mortality worldwide with limited effective therapy. S...

    Authors: Huang-Chi Chen, Chia-Yu Kuo, Yu Chang, Dong-Lin Tsai, Mei-Hsuan Lee, Jui-Ying Lee, Hui-Ming Lee and Yu-Chieh Su
    Citation: BMC Cancer 2024 24:248
    Content type: Research Published on:

  47. In 2017, the New South Wales Cancer Registry (NSWCR) participated in a project, supported by Cancer Australia, aiming to provide national stage data for melanoma, prostate, colorectal, breast, and lung cancers...

    Authors: Sheena Lawrance, Chau Bui, Vidur Mahindra, Maria Arcorace and Claire Cooke-Yarborough
    Citation: BMC Cancer 2019 19:850
    Content type: Research article Published on:

  48. Lung cancer is the leading cause of malignancy-related mortality and lung adenocarcinoma accounts for about 40% of lung malignancies. The aim of this study was to investigate the associations of intraflagellar...

    Authors: Lianfeng Li, Yaobing Chen, Wei Liao, Qimei Yu, Hui Lin, Yuqin Shi, Ling Zhang, Guoqing Fu, Zhenyu Wang, Xi Li, Xianrong Kong, Ting Zhou and Lingzhi Qin
    Citation: BMC Cancer 2022 22:809
    Content type: Research Published on:

  49. The systemic inflammatory response resulting from the complex interactions between cancer and the host plays an important role in cancer development. Recently, the lymphocyte-C-reactive protein ratio (LCR), wh...

    Authors: Kozo Miyatani, Shohei Sawata, Masahiro Makinoya, Wataru Miyauchi, Shota Shimizu, Yuji Shishido, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Shuichi Takano, Teruhisa Sakamoto, Toshimichi Hasegawa, Hiroaki Saito and Yoshiyuki Fujiwara
    Citation: BMC Cancer 2022 22:641
    Content type: Research Published on:

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