Table 2 Meta-analyses of up-regulated TRIM expressions and clinicopathological parameters
Clinicopathological parameter | Studies (n) | OR (95% CI) | P-value | Heterogeneity | ||
|---|---|---|---|---|---|---|
I2 (%) | PQ | Model | ||||
Gender (male vs. female) | 10 | 1.04 (0.82-1.33) | 0.725 | 0.0 | 0.642 | fixed |
Tumor depth (T3-4 vs. T1-2) | 7 | 2.01 (1.04-3.88) | 0.039 | 71.2 | 0.002 | random |
Lymph node metastasis (+ vs. -) | 7 | 2.99 (2.19-4.09) | <0.0001 | 0.0 | 0.798 | fixed |
Distant metastasis (+ vs. -) | 9 | 0.92 (0.39-2.19) | 0.855 | 66.2 | 0.003 | random |
TNM stage (III-IV vs. I-II) | 9 | 2.26 (1.25-4.10) | 0.007 | 77.2 | 0.0005 | random |
Poorly/undifferentiated vs. Well/moderately | 7 | 0.63 (0.44-0.90) | 0.01 | 38.4 | 0.136 | fixed |
Location (colon vs. rectum) | 5 | 0.93 (0.65-1.33) | 0.673 | 0.0 | 0.416 | fixed |
Perineural invasion (+ vs. -) | 3 | 1.95 (1.18-3.23) | 0.009 | 0.0 | 0.442 | fixed |