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Table 1 Baseline characteristics of German Chronic Kidney Disease (GCKD) study patients stratified by cancer statusa

From: Apolipoprotein A-IV concentrations and cancer in a large cohort of chronic kidney disease patients: results from the GCKD study

 

Non-cancer (n = 4056)b

Prevalent cancer (n = 615)b

Incident cancer (n = 368)b

ApoA-IV (mg/dL)

29.0 ± 9.9 [22.0; 27.9; 34.4]

28.1 ± 9.1 [21.6; 26.4; 33.0]

28.7 ± 10.1 [22.0; 27.1; 33.9]

Age (years)

59 ± 12 [51; 62; 69]

65 ± 9 [60; 68; 71]

65 ± 9 [62; 68; 71]

Female sex, n (%)

1653 (40.8%)

246 (40.0%)

106 (28.8%)

eGFR (mL/min/1.73m2)c

51 ± 20 [36; 47; 61]

48 ± 18 [35; 46; 59]

45 ± 17 [33; 42; 54]

UACR (mg/g)d

448 ± 962 [10; 55; 422]

365 ± 1035 [7; 30; 210]

343 ± 782 [10; 49; 286]

Body mass index, (kg/m2)

29.7 ± 6.0 [25.6;28.8;33.1]

29.9 ± 5.7 [25.8;29.1;33.2]

30.5 ± 5.5 [27.2;29.6;33.8]

Hs-CRP, (mg/L)

4.6 ± 8.0 [1.0; 2.2; 4.9]

5.3 ± 8.8 [1.2; 2.5; 5.7]

5.4 ± 10.1 [1.4; 2.7; 5.7]

LDL cholesterol, (mg/dL)

119 ± 44 [90; 115; 143]

116 ± 43 [86; 112; 139]

113 ± 41 [84; 109; 142]

HDL cholesterol, (mg/dL)

52 ± 18 [40; 49; 62]

51 ± 19 [38; 47; 61]

50 ± 18 [38; 45; 59]

Triglycerides, (mg/dL)

199 ± 129 [118; 168; 239]

202 ± 120 [116; 169; 245]

202 ± 133 [120; 170; 246]

Smoker and ex-smoker, n (%)

2354 (58.0%)

373 (60.7%)

239 (65.0%)

Diabetes, n (%)

1383 (34.1%)

241 (39.2%)

162 (44.0%)

Statin use, n (%)

1918 (47.3%)

273 (44.4%)

204 (55.4%)

  1. Data are provided as mean ± SD [25th, 50th (median) and 75th percentile or number (%), (percentage considering missing values). Hs-CRP and urine-albumin values that were below the lower detection limit (LOD) were replaced by LOD/√2. BMI was corrected for amputation
  2. aStudy participants are stratified by non-cancer patients (did not have cancer before enrolment and also not during follow-up), prevalent cancer patients (those with a history of cancer before enrolment), and incident cancer patients (those who developed a new cancer event during follow-up which has not been experienced before enrolment)
  3. bNumber of patients based on those with available data on age, sex, eGFRcys, urine albumin-creatinine ratio (UACR), apolipoprotein A-IV measurements, cancer information and censoring date
  4. ceGFR denotes glomerular filtration rate calculated according to the CKD-EPI equation based on cystatin C [38]
  5. dUACR was calculated according to the following equation: albumin in urine (mg/l) × 100 / creatinine in urine (mg/dl) and is given in mg/g