Table 7 Univariate analysis of clinicopathological characteristics associated with overall survival

BCLC (B-C)

(2.659–5.327)

 < 0.001

PVTT (positive)

(3.985–13.664)

 < 0.001

Tumor cap (complete)

(0.163–0.409)

 < 0.001

Tumor number (multiple)

(1.083–3.040)

 < 0.001

M-CTC (positive)

(2.015–5.037)

 < 0.001

MVI (positive)

(1.704–4.496)

 < 0.001

AFP (≥ 400 ng/mL)

(1.499–3.730)

 < 0.001

VCE (positive)

(1.383–3.401)

 < 0.001

Ki67 (≥ 50%)

(1.438–3.525)

 < 0.001

Tumor size (≥ 5)

(1.083–3.040)

0.023

EdmondsIII–IV

(1.018–2.417)

0.041

Liver cirrhosis (positive)

(1.041–10.828)

0.042

M-CTC + Ki67

(3.019–12.024)

 < 0.001

HBsAg (positive)

(0.813–3.539)

0.159

Age (≥ 45)

(0.485–1.160)

0.196

HBV-DNA (≥ 5 × 10² IU/mL)

(0.685–1.786)

0.677

Sex (M/F)

(0.481–1.817)

0.844