Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209–49.
Article
PubMed
Google Scholar
MOPH. National Cancer Registry (NCR). 2016. https://moph.gov.lb/en/DynamicPages/index/8/19526/national-cancer-registry.
Antoine AR, Joyce S, Joanna S, Christine K, Khoury Salem E, Philippe S. Gastrointestinal cancer characteristics in Lebanon. Arab J Gastroenterol. 2022;23:52–7.
Article
PubMed
Google Scholar
Thrift AP, Nguyen TH. Gastric Cancer Epidemiology. Gastrointest Endosc Clin N Am. 2021;31:425–39.
Article
PubMed
Google Scholar
Hu HM, Tsai HJ, Ku HY, Lo SS, Shan YS, Chang HC, et al. Survival outcomes of management in metastatic gastric adenocarcinoma patients. Sci Reports 2021 111. 2021;11:1–9.
Lou L, Wang L, Zhang Y, Chen G, Lin L, Jin X, et al. Sex difference in incidence of gastric cancer: an international comparative study based on the Global Burden of Disease Study 2017. BMJ Open. 2020;10:e033323.
Article
PubMed
PubMed Central
Google Scholar
Sarkar S, Dauer MJ, In H. Socioeconomic Disparities in Gastric Cancer and Identification of a Single SES Variable for Predicting Risk. J Gastrointest Cancer. 2022;53:170–8.
Article
PubMed
Google Scholar
Martimianaki G, Bertuccio P, Alicandro G, Pelucchi C, Bravi F, Carioli G, et al. Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium. Eur J Cancer Prev. 2022;31:117–27.
CAS
PubMed
PubMed Central
Google Scholar
Poorolajal J, Moradi L, Mohammadi Y, Cheraghi Z, Gohari-Ensaf F. Risk factors for stomach cancer: a systematic review and meta-analysis. Epidemiol Health. 2020;42:e2020004.
Article
PubMed
PubMed Central
Google Scholar
Deng W, Jin L, Zhuo H, Vasiliou V, Zhang Y. Alcohol consumption and risk of stomach cancer: a meta-analysis. Chem Biol Interact. 2021;336:109365.
Article
CAS
PubMed
Google Scholar
Zádori N, Szakó L, Váncsa S, Vörhendi N, Oštarijaš E, Kiss S, et al. Six autoimmune disorders are associated with increased incidence of gastric cancer: a systematic review and meta-analysis of half a million patients. Front Immunol. 2021;12:750533.
Article
PubMed
PubMed Central
Google Scholar
Jin G, Lv J, Yang M, Wang M, Zhu M, Wang T, et al. Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. Lancet Oncol. 2020;21:1378–86.
Article
CAS
PubMed
Google Scholar
Yusefi AR, Lankarani KB, Bastani P, Radinmanesh M, Kavosi Z. Risk factors for gastric cancer: a systematic review. Asian Pac J Cancer Prev. 2018;19:591.
CAS
PubMed
PubMed Central
Google Scholar
Plummer M, Franceschi S, Vignat J, Forman D, De Martel C. Global burden of gastric cancer attributable to Helicobacter pylori. Int J cancer. 2015;136:487–90.
Article
CAS
PubMed
Google Scholar
Yang L, Kartsonaki C, Yao P, de Martel C, Plummer M, Chapman D, et al. The relative and attributable risks of cardia and non-cardia gastric cancer associated with Helicobacter pylori infection in China: a case-cohort study. Lancet Public Heal. 2021;6:e888–96.
Article
Google Scholar
Castagneto-Gissey L, Casella-Mariolo J, Casella G, Mingrone G. Obesity surgery and cancer: what are the unanswered questions? Front Endocrinol (Lausanne). 2020;11:213.
Article
Google Scholar
Alshehri A, Alanezi H, Kim BS. Prognosis factors of advanced gastric cancer according to sex and age. World J Clin Cases. 2020;8:1608.
Article
PubMed
PubMed Central
Google Scholar
Van Cutsem E, Bang YJ, Feng-yi F, Xu JM, Lee KW, Jiao SC, et al. HER2 screening data from ToGA: targeting HER2 in gastric and gastroesophageal junction cancer. Gastric Cancer. 2015;18:476.
Article
PubMed
Google Scholar
Lei YY, Huang JY, Zhao QR, Jiang N, Xu HM, Wang ZN, et al. The clinicopathological parameters and prognostic significance of HER2 expression in gastric cancer patients: a meta-analysis of literature. World J Surg Oncol. 2017;15:68.
Article
PubMed
PubMed Central
Google Scholar
Wang Y, He L, Cheng Y. An independent survival prognostic role for human epidermal growth factor receptor 2 in gastric cancer: evidence from a meta-analysis. Clin Transl Oncol. 2018;20:212–20.
Article
PubMed
Google Scholar
Li H, Li L, Zhang N, Wang Z, Xu N, Linghu E, et al. Relationship between HER2 overexpression and long-term outcomes of early gastric cancer: a prospective observational study with a 6-year follow-up. BMC Gastroenterol. 2022;22:1–7.
Article
Google Scholar
Kim TH, Do Cho H, Choi YW, Lee HW, Kang SY, Jeong GS, et al. Trastuzumab-based palliative chemotherapy for HER2-positive gastric cancer: a single-center real-world data. BMC Cancer. 2021;21:1–8.
Article
CAS
Google Scholar
Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet (London, England). 2010;376:687–97.
Article
CAS
Google Scholar
Nicole McMillian N, Lenora Pluchino MA, Ajani JA, D TA, Chair V, Bentrem DJ, et al. NCCN Guidelines Version 2.2022 Gastric Cancer. 2022.
Xie SD, Xu CY, Shen JG, Jiang ZN, Shen JY, Wang LB. HER 2/neu protein expression in gastric cancer is associated with poor survival. Mol Med Rep. 2009;2:943–6.
CAS
PubMed
Google Scholar
Viera AJ, Garrett JM. Understanding interobserver agreement: the kappa statistic. Fam Med. 2005;37:360–3.
PubMed
Google Scholar
Mukherji D, Salim Hammoud M, Charafeddine M, Temraz S, Shamseddine A. Evaluation of morphology, HER2 status and its clinical and prognostic correlation in advanced gastric cancer: a prospective study at a tertiary referral center in Lebanon. Ann Oncol. 2017;28:iii35.
Article
Google Scholar
Kim W-H, Gomez-Izquierdo L, Vilardell F, Chu K-M, Soucy G, dos Santos LV, et al. HER2 Status in Gastric and Gastroesophageal Junction Cancer: Results of the Large, Multinational HER-EAGLE Study. Appl Immunohistochem Mol Morphol. 2018;26:239–45.
Article
CAS
PubMed
Google Scholar
Chua TC, Merrett ND. Clinicopathologic factors associated with HER2-positive gastric cancer and its impact on survival outcomes–a systematic review. Int J cancer. 2012;130:2845–56.
Article
CAS
PubMed
Google Scholar
Assi T, El Rassy E, Khazzaka A, Moussa T, Ibrahim T, Kattan C, et al. Characteristics of gastric cancer in Lebanon: a descriptive study from a single institutional experience. J Gastrointest Cancer 2016 491. 2016;49:21–4.
Aoude M, Mousallem M, Abdo M, Youssef B, Kourie HR, Al-Shamsi HO. Gastric cancer in the Arab World: a systematic review. Rev EMHJ (WHO EMRO). 2022;28:521–31.
Ramazani Y, Mardani E, Najafi F, Moradinazar M, Amini M. Epidemiology of Gastric Cancer in North Africa and the Middle East from 1990 to 2017. J Gastrointest Cancer. 2021;52:1046–53.
Article
PubMed
Google Scholar
Charafeddine MA, Olson SH, Mukherji D, Temraz SN, Abou-Alfa GK, Shamseddine AI. Proportion of cancer in a Middle eastern country attributable to established risk factors. BMC Cancer. 2017;17:1–11.
Article
Google Scholar
Dogan I, Karabulut S, Tastekin D, Ferhatoglu F, Paksoy N, Sakar B. Evaluation of Prognostic Factors and Trastuzumab-based Treatments in HER2/Neu-positive Metastatic Gastric Cancer. J Coll Physicians Surg Pak. 2022;32:1014–9.
Article
PubMed
Google Scholar
Topcu A, Atci MM, Secmeler S, Besiroglu M, Ayhan M, Ozkan M, et al. Efficacy of trastuzumab and potential risk factors on survival in patients with HER2-positive metastatic gastric cancer. Future Oncol. 2021;17:4157–69.
CAS
PubMed
Google Scholar
Waskito LA, Rezkitha YAA, Vilaichone R, Sugihartono T, Mustika S, Dewa Nyoman Wibawa I, et al. The role of non-Helicobacter pylori bacteria in the pathogenesis of gastroduodenal diseases. Gut Pathog. 2022;14:19.
Pop R, Tăbăran A-F, Ungur AP, Negoescu A, Cătoi C. Helicobacter Pylori-induced gastric infections: from pathogenesis to novel therapeutic approaches using silver nanoparticles. Pharmaceutics. 2022;14:1463.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhu L, Huang Y, Li H, Shao S. Helicobacter pylori promotes gastric cancer progression through the tumor microenvironment. Appl Microbiol Biotechnol. 2022;106:4375.
Article
CAS
PubMed
Google Scholar
Oster P, Vaillant L, McMillan B, Velin D. The Efficacy of Cancer Immunotherapies Is Compromised by Helicobacter pylori Infection. Front Immunol. 2022;13:899161.
Article
CAS
PubMed
PubMed Central
Google Scholar
Satala CB, Jung I, Stefan-Van Staden RI, Kovacs Z, Molnar C, Bara TB, et al. HER2 heterogeneity in gastric cancer: a comparative study ,using two commercial antibodies. J Oncol. 2020;2020:8860174.
Article
PubMed
PubMed Central
Google Scholar
Pyo JS, Sohn JH, Kim WH. Concordance rate between HER2 immunohistochemistry and in situ hybridization in gastric carcinoma: systematic review and meta-analysis. Int J Biol Markers. 2016;31:e1-10.
Article
PubMed
Google Scholar
Fox SB, Kumarasinghe MP, Armes JE, Bilous M, Cummings MC, Farshid G, et al. Gastric HER2 Testing Study (GaTHER): an evaluation of gastric/gastroesophageal junction cancer testing accuracy in Australia. Am J Surg Pathol. 2012;36:577–82.
Article
PubMed
Google Scholar