Comprehensive analysis of the expression and prognosis for IQ motif-containing GTPase-activating proteins in hepatocellular carcinoma

Table 1 Correlation between the clinicopathologic variables and IQGAP1/2/3 expression in HCC patients

Variables	N	IQGAP1		P value	IQGAP2		P value	IQGAP3		P value
Variables	N	Positive	Negative	P value	Positive	Negative	P value	Positive	Negative	P value
Age				0.332			0.073			0.561
>55	165	124	41		37	128		109	56
≤55	85	59	26		28	57		53	32
Sex				0.764			0.198			0.242
Male	219	161	58		54	165		139	80
Female	31	22	9		11	20		23	8
HBV infection				0.378			0.963			0.638
Present	189	141	48		49	140		124	65
Absent	61	42	19		16	45		38	23
Liver cirrhosis				0.793			0.435			0.643
Present	160	118	42		39	121		102	58
Absent	90	65	25		26	64		60	30
AFP level				0.864			0.951			0.276
>400 ng/mL	80	58	22		21	59		48	32
≤ 400 ng/mL	170	125	45		44	126		114	56
Tumor size				0.031			0.486			0.848
>5 cm	140	110	30		34	106		90	50
≤ 5 cm	110	73	37		31	79		72	38
Tumor number				0.766			0.039			0.599
Multiple	44	33	11		6	38		27	17
Solitary	206	150	56		59	147		135	71
Microvascular invasion				0.345			0.011			0.838
Present	55	43	12		7	48		35	20
Absent	195	140	55		58	137		127	68
Differentiation degree				0.613			0.352			< 0.001
Poor and moderate	173	125	48		42	131		126	47
Well	77	58	19		23	54		36	41
TNM stage				0.016			0.935			0.622
I and II	203	142	61		53	150		133	70
III and IV	47	41	6		12	35		29	18

ISSN: 1471-2407