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Table 2 P-values of log-rank test and Hazard ratio for pathways, which were associated with PFS in three datasets investigated (experimental, TCGA, and Syn2623706)

From: Personalized targeted therapy prescription in colorectal cancer using algorithmic analysis of RNA sequencing data

Dataset

experimental

TCGA

Syn2623706

experimental

TCGA

Syn2623706

Pathway

Hazard ratio

p-value of log-rank test

KEGG Bladder cancer Pathway

6.21

1.47

0.72

1.84E-02

4.80E-02

1.84E-02

NCI Signaling events mediated by HDAC Class II Pathway

0.16

0.63

0.56

6.11E-05

1.68E-02

6.11E-05

KEGG cGMP PKG signaling Pathway

6.21

1.46

1.56

1.54E-03

4.30E-02

1.54E-03

NCI E cadherin signaling in keratinocytes Pathway

6.21

1.71

1.56

1.64E-03

5.92E-03

1.64E-03

KEGG Aldosterone regulated sodium reabsorption Pathway

5.38

1.50

1.54

2.52E-03

3.11E-02

2.52E-03